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  1. 1301

    核苷(酸)类似物治疗慢性HBV感染者至HBV DNA阴转后ALT异常的因素分析

    Published 2014-01-01
    “…【目的】 探明慢性乙型肝炎病毒(HBV)感染者接受核苷(酸)类似物(NA)治疗至HBV DNA降至不可检测水平后,丙氨酸氨基转移酶(ALT)仍然异常的高危因素。【方法】2006年1月至2014年2月期间,回顾加前瞻性随访核苷(酸)类似物初始治疗至HBV DNA阴转(<20 IU/mL)后的慢性HBV感染者(n = 388),对比ALT复常者(n= 298)及异常者[n = 90;定义为在每1 ~ 3个月的随访间隔中,连续2次以上ALT > 40 U/L(男)或 > 35 U/L(女)]的临床特征,使用logistic多因素回归分析ALT异常的高危因素。…”
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  2. 1302

    Does hydrogen-rich water mitigate MP toxicity in rainbow trout (Oncorhyncus mykiss)? Monitoring with hematology, DNA damage, and apoptosis via ROS/GSH/MDA pathway by Atamanalp Muhammed, Kırıcı Muammer, Köktürk Mine, Kırıcı Mahinur, Alwazeer Duried, Kocaman Esat Mahmut, Ucar Arzu, Parlak Veysel, Özcan Sinan, Alak Gonca

    Published 2023-06-01
    “…In this direction, the following were determined: PP+PE chronic toxicity in aquatic organisms, the toxicity mechanism and the effect of HRW as a possible treatment method in blood tissue; with hematological indices ([RBC count [RBC], leukocyte count [WBC], hemoglobin value [Hb], hematocrit ratio [Hct], platelet count [PLT], hemoglobin count per erythrocyte [MCHC], mean hemoglobin amount per erythrocyte [MCH] and mean erythrocyte volume [MCV]) in other tissues (liver, gill and brain tissue) oxidative stress response (catalase [CAT]), glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), glutathione (GSH), reactive oxygen products (ROS), malondialdehyde ([MDA] levels), DNA damage (8-OHdG: 8-Hydroxy-2-Deoxyguanosine), and the apoptosis (caspase 3) levels were investigated. …”
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  3. 1303

    Plant Compounds Inhibit the Growth of W12 Cervical Precancer Cells Containing Episomal or Integrant HPV DNA; Tanshinone IIA Synergizes with Curcumin in Cervical Cancer Cells by Linda Saxe Einbond, Jing Zhou, Kunhui Huang, Mario R. Castellanos, Emeka Mbazor, Michael Balick, Hongbao Ma, James A. DeVoti, Stephen Redenti, Hsan-au Wu

    Published 2024-12-01
    “…W12 cells, derived from a cervical precancerous lesion, contain either episomal or integrated HPV16 DNA. Several compounds, including digoxin, tanshinone IIA, dihydromethysticin and carrageenan, as well as fractions of turmeric, ginger and pomegranate inhibited the growth of W12 precancer and cervical cancer cells. …”
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  4. 1304
  5. 1305

    Cancer Stem Cells from Tumor Cell Lines Activate the DNA Damage Response Pathway after Ionizing Radiation More Efficiently Than Noncancer Stem Cells by Heriberto Abraham Valencia-González, Graciela Ruíz, Elizabeth Ortiz-Sánchez, Alejandro García-Carrancá

    Published 2019-01-01
    “…CSC are proposed to repair DNA damage more efficiently than the rest of tumor cells, resisting chemotherapy or radiotherapy and causing clinical recurrence and metastasis. …”
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    Debatten i debatten by Jenny Eklöf

    Published 2024-12-01
    Subjects: “…hybrid-DNA-teknik…”
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  16. 1316

    Genetic Evidence for Geographic Structure within the  Neanderthal Population by Rogers, Alan R.

    Published 2024-07-01
    Subjects: “…Neanderthals; ancient DNA; geographic population structure; extinction; population history…”
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