DNA 末端标记法检测番荔枝内酯诱导人乳癌细胞凋亡

“…目的: 用 DNA 末端标记法( TUNEL 法)研究番荔枝内酯凋亡诱导作用,以及 TUNEL 法用于凋亡检测和抗癌药 所致凋亡的探讨。…”
Get full text

畸型精子症患者精子DNA 完整性与年龄及常规精液参数的关系 by 郭丽媛, 周华, 王晓蔓, 刘敏

Subjects: Get full text

Methylated H3K4, a transcription-associated histone modification, is involved in the DNA damage response pathway. by David Faucher, Raymund J Wellinger

“…Post-translational histone modifications are associated with regulatory aspects executed by chromatin and all transactions on genomic DNA are dependent on them. Thus, it will be relevant to understand how histone modifications affect genome functions. …”
Get full text

The role of the microbiota and metabolites in the treatment of pulmonary fibrosis with UC-MSCs: Integrating fecal metabolomics and 16S rDNA analysis. by Yukai Luo, Shuang Zhou, Xiaojing Zhang, Yijian Lin, Jun Liu, Wenzhao Cheng, Yiming Zeng

“…Fecal samples from six mice in each of the Control group, Model group, and UC-MSCs-M groups were collected randomly for 16S rDNA sequencing to analyze the gut microbiota and nontargeted metabolomics.…”
Get full text

Combined biochemical profiling and DNA sequencing in the expanded newborn screening for inherited metabolic diseases: the experience in an Italian reference center by Simona Fecarotta, Lorenzo Vaccaro, Alessandra Verde, Marianna Alagia, Alessandro Rossi, Chiara Colantuono, Maria Teresa Cacciapuoti, Patrizia Annunziata, Sara Riccardo, Antonio Grimaldi, Tonya Fusco, Rosa De Santis, Fernando Barretta, Lucia Albano, Daniela Crisci, Fabiana Vallone, Antonietta Tarallo, Marcella Cesana, Nicola Brunetti-Pierri, Giulia Frisso, Margherita Ruoppolo, Davide Cacchiarelli, Giancarlo Parenti

Get full text

~3H—TdR体外参入法测定癌组织DNA合成水平的研究 by 焦晓蓉

“…六十年代至今,组织DNA合成水平的研究多用放射性自显影法。但此法程序繁杂,需时长,细胞计数工作量大。因此,我们将组织放射自显影法加以改进,用液体闪烁计数的方法测定癌组织的同位素参入量,从而得知组织的DNA合成水。…”
Get full text

Development of a cell-penetrating peptide-based nanocomplex for long-term delivery of intact mitochondrial DNA into epithelial cells by Kyrie Wilson, Charles Holjencin, Hwaran Lee, Balasubramaniam Annamalai, Masaaki Ishii, Jeremy L. Gilbert, Andrew Jakymiw, Bärbel Rohrer

Subjects: Get full text

Abnormal Expression of DNA Double-Strand Breaks Related Genes, ATM and GammaH2AX, in Thyroid Carcinoma by Jin-lin Hu, Si-si Hu, Xiu-xiu Hou, Xin Zhu, Jun Cao, Lie-hao Jiang, Ming-hua Ge

“…ATM and γH2AX play a vital role in the detection of DNA double-strand breaks (DSB) and DNA damage response (DDR). …”
Get full text

Correction: A prospective cohort study of dynamic cell-free DNA elevation during cardiac surgery with cardiopulmonary bypass. by Shlomo Yaron Ishay, Muhammad Abu-Tailakh, Lior Raichel, Tal F Hershenhoren, Menahem Matsa, Oren Lev-Ran, Sahar Gideon, Amos Douvdevani

Get full text

ParSite is a multicolor DNA labeling system that allows for simultaneous imaging of triple genomic loci in living cells. by Xiaohui He, Yadong Sun, Hanhui Ma

“…Here, we developed a multicolor DNA labeling system, ParSite, to simultaneously track triple genomic loci in the U2OS cells. …”
Get full text

Sir2 and Fun30 regulate ribosomal DNA replication timing via MCM helicase positioning and nucleosome occupancy by Carmina Lichauco, Eric J Foss, Tonibelle Gatbonton-Schwager, Nelson F Athow, Brandon Lofts, Robin Acob, Erin Taylor, James J Marquez, Uyen Lao, Shawna Miles, Antonio Bedalov

Subjects: Get full text

Identification and Quality Evaluation of Raw and Processed Asarum Species Using Microscopy, DNA Barcoding, and Gas Chromatography-Mass Spectrometry by Guangzhe Yao, Wenjuan Ma, Xuhua Huang, Qi Jia, Jiayuan Shen, Yanxu Chang, Huizi Ouyang, Jun He

“…In this study, 16 batches of Asarum herbs were collected, and their species were identified using DNA barcoding, which is a method for distinguishing plant species, coupled with microscopy. …”
Get full text

Probe into Application of DNA03 Digital Level to Detection of Deformation of Earth-rock Dam in Small Medium Sized Reservo by TANG Ying-gui, CHEN Si-qi, LI Ai-jun

Get full text

电泳印迹和分子杂交技术在肝内HBV DNA研究中的应用

Subjects: Get full text

Using DNA metabarcoding and direct behavioural observations to identify the diet of proboscis monkeys (Nasalis larvatus) in the Kinabatangan Floodplain, Sabah. by Valentine Thiry, Arthur F Boom, Danica J Stark, Olivier J Hardy, Roseline C Beudels-Jamar, Regine Vercauteren Drubbel, Sylvia Alsisto, Martine Vercauteren, Benoit Goossens

“…In addition, we built a DNA reference database with the local plants available in the LKWS. …”
Get full text

Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts by Muataz S. Lafta, Aleksandr V. Sokolov, Gull Rukh, Helgi B. Schiöth

Get full text

SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA by Eri Inoue, Keizo Tano, Hanako Yoshii, Jun Nakamura, Shusuke Tada, Masami Watanabe, Masayuki Seki, Takemi Enomoto

“…Reactive oxygen species (ROSs) are produced during normal cellular metabolism, particularly by respiration in mitochondria, and these ROSs are considered to cause oxidative damage to macromolecules, including DNA. In our previous paper, we found no indication that depletion of mitochondrial superoxide dismutase, SOD2, resulted in an increase in DNA damage. …”
Get full text

Synthesis, Spectroscopic Characterisation, and Biopotential and DNA Cleavage Applications of Mixed Ligand 4-N,N-Dimethylaminopyridine Metal Complexes by C. Surendra Dilip, K. Manikandan, D. Rajalaxmi (a) Subahashini, R. Thiruneelakandan

“…The antimicrobial studies against various pathogenic bacterial and fungal serums insist on that the enhanced potential of the complexes over their ligand and their biopotential properties increases with concentration. The DNA interaction of the synthesized complexes on CT-DNA was investigated by UV-Vis spectroscopy, viscosity, thermal denaturation, and electroanalytical experiments and their binding constants () were also calculated.…”
Get full text

Identification of Factors Influencing Donor-Derived Cell-Free DNA Levels up to One Year After Kidney Transplant by Ahmad Mirza, Imran Gani, Imran Parvez, Cari Weaver, Laura Mulloy, Rajan Kapoor

“…Conclusion: This study provides further insight into donor and recipient variables’ effects on dd-cfDNA in the early posttransplant phase by analyzing a more diverse cohort of patients and adds to the knowledge around interpreting dd-cfDNA scores with clinical correlation for posttransplant management.…”
Get full text

Advancements in functional tetrahedral DNA nanostructures for multi-biomarker biosensing: Applications in disease diagnosis, food safety, and environmental monitoring by Yun Qiu, Yixing Qiu, Wenchao Zhou, Dai Lu, Huizhen Wang, Bin Li, Bin Liu, Wei Wang

Subjects: “…Functional tetrahedral DNA nanostructure…”
Get full text