Showing 601 - 620 results of 5,516 for search '"DNA', query time: 0.16s Refine Results
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    Low dose DNA methyltransferase inhibitors potentiate PARP inhibitors in homologous recombination repair deficient tumors by Romain Pacaud, Scott Thomas, Sibapriya Chaudhuri, Ann Lazar, Luika A. Timmerman, Pamela N. Munster

    Published 2025-01-01
    “…Conclusions We conclude that low dose DNA methyltransferase inhibition can cooperate with low dose PARP inhibition to increase DNA damage predominantly in cells with HRR deficiencies, ultimately producing more cell death than in HRR proficient tumors. …”
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    R-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania by Jeziel D. Damasceno, Emma M. Briggs, Marija Krasilnikova, Catarina A. Marques, Craig Lapsley, Richard McCulloch

    Published 2025-02-01
    “…Abstract Genomes in eukaryotes normally undergo DNA replication in a choreographed temporal order, resulting in early and late replicating chromosome compartments. …”
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  7. 607

    Detection of Mycobacterium tuberculosis DNA in intraocular fluid of 11 suspected tuberculous uveitis patients by multiplex PCR by Huirong Xu, Min Xu, Fang Chen, Hong Chen, Wei Du, Jing Yu

    Published 2025-01-01
    “…Multiplex PCR was conducted using DNA from the H37Rv strain as well as DNA extracted from fluids of confirmed tuberculosis patients to assess primer specificity and method feasibility. …”
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    Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer by Daniele Calistri, Claudia Rengucci, Chiara Molinari, Enrico Ricci, Elena Cavargini, Emanuela Scarpi, Gian Luigi Milandri, Carla Fabbri, Alberto Ravaioli, Antonio Russo, Dino Amadori, Rosella Silvestrini

    Published 2009-01-01
    “…We aimed to validate the diagnostic accuracy, using the same threshold as in the previous pilot study, of fluorescent long DNA test as a relatively simple and inexpensive tool for colorectal cancer detection.…”
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    Bacteroides expand the functional versatility of a conserved transcription factor and transcribed DNA to program capsule diversity by Jason Saba, Katia Flores, Bailey Marshall, Michael D. Engstrom, Yikai Peng, Atharv S. Garje, Laurie E. Comstock, Robert Landick

    Published 2024-12-01
    “…Here, we use in-vivo nascent-RNA sequencing and promoter-less in-vitro transcription (PIVoT) to show that UpxY recognizes a paused RNA polymerase via sequences in both the exposed non-template DNA and the upstream duplex DNA. UpxY association is aided by ‘pause-then-escape’ nascent RNA hairpins. …”
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    Generation of microdissected DNA probes from metaphase chromosomes when chromosome identification by routine staining is impossible by K. S. Zadesenets, N. B. Rubtsov

    Published 2020-08-01
    “…Application of microdissected DNA libraries and DNA probes in numerous and various modern molecular cytogenetic studies showed them as an efficient and reliable tool in the analysis of chromosome reorganization during karyotypic evolution and in the diagnosis of human chromosome pathology. …”
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  14. 614

    Integrating 16S rDNA and metabolomics to uncover the therapeutic mechanism of electroacupuncture in type 2 diabetic rats by Zhang Yue, Wang Xiang, Deng Duping, Gong Yuanyuan, Chen Xuanyi, Li Juan, Li Juan, Hong Xiaojuan

    Published 2025-01-01
    “…Fecal microbial communities were analyzed by 16S rDNA sequencing, and short-chain fatty acids (SCFAs) were measured using gas chromatography–mass spectrometry (GC–MS). …”
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    Indocarbocyanine–Indodicarbocyanine (sCy3–sCy5) Absorptive Interactions in Conjugates and DNA Duplexes by Evgeny L. Gulyak, Vladimir A. Brylev, Mikhail Y. Zhitlov, Olga A. Komarova, Alexey V. Ustinov, Ksenia A. Sapozhnikova, Vera A. Alferova, Vladimir A. Korshun, Daniil A. Gvozdev

    Published 2024-12-01
    “…However, when the two dyes are separated by long rigid DNA-based spacers, the absorbance ratio becomes consistent with their individual molar absorption coefficients. …”
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  17. 617

    Protocol to Identify Unknown Flanking DNA Using Partially Overlapping Primer-based PCR for Genome Walking by Mengya Jia, Dongqin Ding, Xiaohua Liu, Haixing Li

    Published 2025-02-01
    “…In the subsequent high-temperature (65 °C) cycle, the target single-stranded DNA is converted into double-stranded DNA by the sequence-specific primer, attributed to the presence of this primer complement, while non-target single-stranded DNA cannot become double-stranded because it lacks a binding site for both primers. …”
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  18. 618

    Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro by Rebecca Lotz, Christian Osterburg, Apirat Chaikuad, Sabrina Weber, Masato Akutsu, Anne Christin Machel, Ulrike Beyer, Jakob Gebel, Frank Löhr, Stefan Knapp, Matthias Dobbelstein, Xin Lu, Volker Dötsch

    Published 2025-01-01
    “…Here we characterize the interaction of iASPP with p63 and show that it binds to the linker region between the DNA binding domain and the oligomerization domain. …”
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    A Color-Image Encryption Scheme Using a 2D Chaotic System and DNA Coding by Haidar Raad Shakir

    Published 2019-01-01
    “…Then, the TD-ERCS system is employed to generate three chaotic sequences before encoding the DNA into the three matrices. Thereafter, a DNA exclusive OR (XOR) operation is executed between the DNA sequences of the permuted image and the DNA sequences generated by the TD-ERCS system to produce three encrypted scrambled matrices. …”
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