Showing 5,021 - 5,040 results of 5,516 for search '"DNA"', query time: 0.06s Refine Results
  1. 5021

    An association between type A porcine endogenous retrovirus copy number and hematological parameters and gender in miniature pigs by R. B. Aitnazarov, S. V. Nikitin, G. V. Kontsevaya, M. I. Voevoda, N. S. Yudin

    Published 2017-12-01
    “…Porcine endogenous retroviruses (PERV) are capable of incorporating copies of DNA into the genome of a host cell. Based on the nucleotide sequence of the envelope gene (env), three main types of pig retrovirus, PERV-A, PERV-B and PERV-C, have been recognized, with PERV-A and PERV-B having the capability of infecting human cell lines in vitro. …”
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  2. 5022

    Nanopore-based random genomic sampling for intraoperative molecular diagnosis by Francesco E. Emiliani, Abdol Aziz Ould Ismail, Edward G. Hughes, Gregory J. Tsongalis, George J. Zanazzi, Chun-Chieh Lin

    Published 2025-01-01
    “…Methods We develop iSCORED, a one-step random genomic DNA reconstruction method that enables efficient, unbiased quantification of genome-wide CNVs. …”
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  3. 5023
  4. 5024

    A meta-analysis of MHC diversity in Pan troglodytes verus by Christelle Vangenot, Alicia Sanchez‑Mazas

    Published 2014-01-01
    “…We performed a meta-analysis of the Major Histocompatibility Complex (MHC) diversity for locus A, B, C, DQB1, DPB1 and DRB1 in Chimpanzees by selecting cohorts of animals for which MHC genotypes were available in publications and by extracting DNA sequences available on the IPD-MHC database. …”
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  5. 5025

    Genetic variation reveals the therapeutic potential of BRSK2 in idiopathic pulmonary fibrosis by Zhe Chen, Mingyang Tang, Nan Wang, Jiangjiang Liu, Xiaoyan Tan, Haitao Ma, Jing Luo, Kai Xie

    Published 2025-01-01
    “…Additionally, we conducted a comprehensive evaluation of therapeutic value, pathogenic mechanisms, and safety through phenome-wide association study (PheWAS), mediation analysis, transcriptomic analyses, shared causal variant exploration, DNA methylation MR, and protein interactions. Results Multiple MR results revealed that BRSK2 has a significant pathogenic impact on IPF at both transcriptional and translational levels, with a lung tissue-specific association (OR = 1.596; CI, 1.300–1.961; Pval = 8.290 × 10 − 6). …”
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  6. 5026

    Reproductive problems in water buffalo cows associated with non-diagnosed genital lepto- spirosis. Preliminary results by Rosaura Pérez-Gil

    Published 2023-11-01
    “…PCR using the marker G1-G2 revealed the presence of Leptospira DNA in 55.5% of uterus, ovary, and oviduct samples, and 44.4% of kidneys; and using the primer Internal 1 and 2 identified pathogenic Leptospira spp, in 55.5% of the uterus and kidney samples, 33.3% in ovaries and 66.6% oviduct. …”
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  7. 5027
  8. 5028
  9. 5029

    TMBocelot: an omnibus statistical control model optimizing the TMB thresholds with systematic measurement errors by Xin Lai, Shaoliang Wang, Xuanping Zhang, Xiaoyan Zhu, Yuqian Liu, Zhili Chang, Zhili Chang, Xiaonan Wang, Xiaonan Wang, Yang Shao, Yang Shao, Jiayin Wang, Yixuan Wang

    Published 2025-01-01
    “…Tumor mutation burden (TMB), defined as the number of somatic mutations of tumor DNA, is a well-recognized immunotherapy biomarker endorsed by regulatory agencies and pivotal in stratifying patients for clinical decision-making. …”
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  10. 5030

    Preclinical evaluation of the potential PARP-imaging probe [carbonyl-11C]DPQ by Katarína Benčurová, Theresa Balber, Victoria Weissenböck, Lukas Kogler, Joachim Friske, Verena Pichler, Markus Mitterhauser, Marcus Hacker, Cécile Philippe, Marius Ozenil

    Published 2025-01-01
    “…Abstract Background Poly (ADP-ribose) polymerase (PARP) enzymes are crucial for the repair of DNA single-strand breaks and have become key therapeutic targets in homologous recombination-deficient cancers, including prostate cancer. …”
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  11. 5031
  12. 5032
  13. 5033

    基于RNA-Seq技术的野生和圈养塔里木马鹿皮肤组织转录组比较分析 by 布威海丽且姆·阿巴拜科日, 单文娟, 马合木提·哈力克, 钟林强

    Published 2023-02-01
    “…相比于圈养塔里木马鹿,皮肤和表皮发育相关基因、DNA损伤修复相关基因、转谷氨酰胺酶编码基因和热休克蛋白家族基因在野生塔里木马鹿皮肤组织中上调表达,表明这些基因可能直接或间接参与塔里木马鹿在极端干旱炎热环境中的皮肤保护策略,通过最大限度地减少水分流失和调节体温来保护机体免受外界刺激的损伤。…”
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  14. 5034
  15. 5035

    基于生物信息学途径评估 UBE2 家族及 UBE2T 基因在肺腺癌中的表达及临床意义 by 杨豪帅, 赖慧娜, 饶怡茹, 林晓平

    Published 2020-01-01
    “…基因富集结果显示高表达的UBE2T与细胞周期(FDR=0),剪接体(FDR=0),DNA修复(FDR=0)及糖代谢等36个信号通路密切相关(FDR<0.05)。UBE2家族的UBE2C、UBE2M、UBE2S、UBE2T、UBE2V2 mRNA均与肺腺癌的临床病理特征存在相关关系,其中UBE2T的表达水平与临床分期及预后的关系最为密切,且与肿瘤细胞糖酵解通路密切相关。…”
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  16. 5036

    Thyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration by Shouhong Wang, Liezhen Fu, Bin Wang, Yanmei Cai, Jianping Jiang, Yun-Bo Shi

    Published 2024-12-01
    “…Interestingly, our findings indicate that amputation-induced changes in DNA replication-related pathways can occur during this nonregenerative period. …”
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  17. 5037

    Using Recombinase-Aid Amplification Combined with <i>Pyrococcus furiosus</i> Argonaute for Rapid Sex Identification in Flamingo (<i>Phoenicopteridae</i>) by Shenluan Tan, Fanwen Zeng, Wanhuan Zhong, Tanzipeng Chen, Xuanjiao Chen, Li Li, Hengxi Wei, Shouquan Zhang

    Published 2024-12-01
    “…The results showed that optimal RAA-<i>Pf</i>Ago conditions could detect 0.6 ng of genomic DNA and effectively differentiate between males and females. …”
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  18. 5038

    SEGS-1 episomes generated during cassava mosaic disease enhance disease severity by Evangelista Chiunga, Evangelista Chiunga, Evangelista Chiunga, Catherine D. Aimone, Cyprian Rajabu, Mary M. Dallas, Joseph Ndunguru, José T. Ascencio-Ibáñez, Elijah M. Ateka, Linda Hanley-Bowdoin

    Published 2025-01-01
    “…In this report, we examined the effects of exogenously applied SEGS-1 on the incidence of CMB infection, symptom severity, and viral DNA copy number in five cassava cultivars that ranged from highly susceptible to highly resistant to CMD. …”
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  19. 5039

    Development of SacB-based counterselection for efficient allelic exchange in Fusobacterium nucleatum by Peng Zhou, Bibek G C, Bo Hu, Chenggang Wu

    Published 2025-01-01
    “…Our molecular comprehension of its role in oral biofilm formation and its interactions with the host under various pathological circumstances has seen considerable advancements in recent years, primarily due to the development of various genetic tools for DNA manipulation in this bacterium. Of these, counterselection-based unmarked in-frame mutation methods have proved notably effective. …”
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  20. 5040