乙肝病毒携带者孕妇胎盘病理学 by 刘颖琳, 刘新质

“…对其中61 例HBV 携带者孕妇胎盘进行详细的组织病理学观察(包括胎儿感染组28 例及对照组33 例), 分级诊断分析, 用PCR、ELISA 法检测胎儿血HBV DNA 和HBsAg 。【结果】①胎儿感染组平均胎盘体积为(638 ±179) cm3 , 小于对照组的(713 ±238)cm3 , 对照组平均胎盘体积小于正常组的(723 ±213)cm3 , P 均小于0.01 ;胎盘厚度、质量、脐长 等在3 组中则无显著性差异;②胎盘大体病理学检查:包括绒毛周围纤维素沉积、胎盘小灶梗死、胎盘边缘血肿、干绒毛动脉 血栓形成、胎盘钙化及胎膜黄染等, 3 组均无显著性差异。…”
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Relatedness of White-Tailed Deer from Culling Efforts Within Chronic Wasting Disease Management Zones in Minnesota by Alberto Fameli, Christopher Jennelle, Jessie Edson, Erik Hildebrand, Michelle Carstensen, W. David Walter

“…We analyzed 11 microsatellites and a mitochondrial DNA fragment to assess: (1) the genetic structure in white-tailed deer in Minnesota, USA and (2) the effectiveness of localized culling to remove related deer. …”
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A novel roseosiphovirus infecting dinoroseobacter shibae DFL12T represents a new genus by Nana Wei, Longfei Lu, Yingying Li, Bo Ding, Lanlan Cai, Yunlan Yang

“…R26L possesses a circular, double-stranded DNA genome of 79,534 bp with a G + C content of 62.6%, encoding a total of 116 open reading frames. …”
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慢性乙肝患者拉米夫定耐药后出现肝功能衰竭的危险因素 by 邓洪, 顾琳, 赵志新, 张晓红, 彭晓谋, 高志良

“…【结果】肝功能衰竭组患者年龄（45±13）岁，大于慢性乙型肝炎组（37±131岁（P〈0．05）；肝功能衰竭组临床耐药时HBV DNA载量高于慢性乙型肝炎组[（2．8×10^8＋4．9×10^8）拷贝／mL vs（3．1×10^6±2．9×10^6）拷贝／mL；P〈0．05]；肝功能衰竭组出现HBeAg／Anti—HBe血清学转换（54．6％）高于慢性乙型肝炎组（18．4％，P〈0．05）。…”
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The implementation and impact of non-invasive prenatal testing (NIPT) for Down's syndrome into antenatal screening programmes: A systematic review and meta-analysis. by Elinor Sebire, Chithramali Hasanthika Rodrigo, Sohinee Bhattacharya, Mairead Black, Rachael Wood, Rute Vieira

“…<h4>Background</h4>Non-invasive prenatal testing (NIPT) is a widely adopted maternal blood test that analyses foetal originating DNA to screen for foetal chromosomal conditions, including Down's syndrome (DS). …”
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Milling degree affects the fermentation properties of rice: perspectives from the composition of nutrients and gut microbiota via in vitro fermentation by Yu Zhang, Fan Li, Shutong Pan, Bing Bai, Kai Huang, Sen Li, Hongwei Cao, Tian Xie, Jian Xie, Xiao Guan

“…Effects of fermentation substrates of rice with different MDs on gut microbiota were evaluated by 16S rDNA sequencing. All the sample groups reduced the pH and produced short-chain fatty acids (SCFAs) and branched-chain fatty acids. …”
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Transplantation of fecal microbiota from low to high residual feed intake chickens: Impacts on RFI, microbial community and metabolites profiles by Chunlin Xie, Qiying Liang, Jiaheng Cheng, Yushan Yuan, Lu Xie, Jian Ji

“…Microbiota composition and functional profiles in LRFI and HFMT chickens formed a distinct cluster compared to HRFI chickens. Using 16S rDNA sequencing and RandomForest analysis, Slackia, Peptococcus, Blautia, and Dorea were identified as key microbial markers associated with feed efficiency. …”
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The Effect of Taxifolin on Cisplatin-Induced Pulmonary Damage in Rats: A Biochemical and Histopathological Evaluation by Edhem Unver, Mustafa Tosun, Hasan Olmez, Mehmet Kuzucu, Ferda Keskin Cimen, Zeynep Suleyman

“…Cisplatin increased the levels of MDA, myeloperoxidase, and 8-OHdG, a marker of oxidative DNA damage, and reduced the amount of tGSH in the lung tissue. …”
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Genomic analysis and replication kinetics of the closely related EHV-1 neuropathogenic 21P40 and abortigenic 97P70 strains by Eslam Mohamed, Ines Zarak, Nick Vereecke, Sebastiaan Theuns, Kathlyn Laval, Hans Nauwynck

“…Isoleucine and asparagine at loci 291 and 207 of ORF30 (DNA polymerase) and ORF65 (ICP22), respectively, were unique to isolates from the Valencia outbreak. …”
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Heterogeneous graph convolutional neural network for protein-ligand scoring by Kevin Crampon, Alexis Giorkallos, Xavier Vigouroux, Stephanie Baud, Luiz Angelo Steffenel

“…Using a representation that involves classical graph neural networks (GNNs) and splitting the learning process regarding the edge type makes the proposed model to be the best adapted for future transfer learning on other (protein-DNA, protein-sugar, protein-protein, etc.) biological complexes.…”
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Performance of the Illumina GGP Bovine 100K SNP array for buffalo populations genotyping in Colombia by William Burgos-Paz, Yolanda Gómez-Vargas, Edison J. Ramírez-Toro

“…Therefore, we conducted an evaluation of single nucleotide polymorphism (SNP) arrays originally designed for cattle to determine their potential applicability in genetic evaluation of Colombian buffalo populations. Eight DNA samples from buffalo individuals belonging to the Murrah, Mediterranean, and crossbred genetic groups were genotyped using the Illumina Bovine HD770K Array. …”
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The frequency of distribution of the genotypes of the IL4 polymorphism (rs 2243250) in psoriasis and psoriatic arthritis by A. A. Barilo, M. V. Smolnikova, S. V. Smirnova

“…The study included patients with psoriasis (n = 49) and psoriatic arthritis (n = 48), which, taking into account the carriage of certain genotypes, are divided into groups: 1, PS, carriers of the C/С genotype (n = 31); 2, PS, carriers of the C/T and T/T genotype (n = 18); 3, PsA, carriers of the C/С genotype (n = 30); and 4, PsA, carriers of the C/T and T/T genotype (n = 18). DNA extraction from whole venous blood was performed using a standard kit with a sorbent. …”
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TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms by Nicholas L. Calistri, Tiera A. Liby, Zhi Hu, Hongmei Zhang, Mark A. Dane, Sean M. Gross, Laura M. Heiser

“…We found that escalating doses of paclitaxel resulted in multinucleation, promotion of senescence, and initiation of DNA damage induced apoptosis. Single-cell RNA sequencing (scRNA-seq) of TNBC cells after paclitaxel treatment revealed upregulation of innate immune programs canonically associated with interferon response and downregulation of cell cycle progression programs. …”
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Genetic Comparison of Stemness of Human Umbilical Cord and Dental Pulp by Chung-Min Kang, Hyunok Kim, Je Seon Song, Byung-Jai Choi, Seong-Oh Kim, Han-Sung Jung, Seok-Jun Moon, Hyung-Jun Choi

“…Comparative gene profiles were obtained using cDNA microarray analysis and the expression of tooth development-associated and MSC-related genes was assessed by the quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR). …”
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Blood Trihalomethanes and Human Cancer: A Systematic Review and Meta-Analysis by Miaomiao Fu, Pengyu Xue, Zhuorong Du, Jingsi Chen, Xiaojun Liang, Jiafu Li

“…Additionally, we discussed the carcinogenic mechanisms of THMs, which involve multiple biological pathways such as oxidative stress, DNA adduct formation, and endocrine disruption, with variations in accumulation and target sites potentially leading to different cancer types, for which evidence is currently lacking. …”
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Putative and pretreatment drug resistance mutations in reverse transcriptase gene among untreated chronic hepatitis B patients at Arifin Achmad Regional District Hospital, Riau, In... by Arfianti Arfianti, Fauzia Andrini Djojosugito, Maisaroh Maisaroh, Hendra Asputra, Dita Kartika Sari, Tubagus Odih Rhomdani Wahid

“…Methods: A total of 26 HBV DNA was extracted from the blood plasma of CHB patients. …”
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In vitro propagation of Codonopsis pilosula (Franch.) Nannf. using apical shoot segments and phytochemical assessments of the maternal and regenerated plants by Roggers, Gang, Richard, Komakech, Yuseong, Chung, Denis, Okello, Wook, Jin Kim, Byeong, Cheol Moon, Nam, Hui Yim, Youngmin, Kang

“…Randomly amplified polymorphic DNA (RAPD) test confirmed the genetic fidelity of regenerated C. pilosula plants. …”
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No microorganism was detected in amniotic fluid of healthy pregnancies from the second trimester to the delivery by Yu Liu, Jingmei Ma, Xiang Li, Haijuan Zhao, Qubo Ai, Lanying Zhang, Yulong Tong, Lingzhen Meng, Huixia Yang

“…Although marginally higher bacterial loads and different bacterial communities were observed in the delivery AF samples compared to negative controls, these bacterial DNA were not considered biologically functional due to the absence of maternal inflammatory responses. …”
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Retrospective evaluation of multiplex PCR panel results from CSF samples in a university hospital by Funda Şahin, Nida Özcan, Erdal Özbek, Selahattin Atmaca, Hakan Temiz

“…The Biospeedy viral nucleic acid isolation kit (Bioeksen, Türkiye) was used for the isolation of genetic material. Genetic materials (DNA/RNA) related to Herpes simplex virus 1-2, Humman herpesvirus 6-7-8, Varicella zoster virus, Enterovirus, Cytomegalovirus, Human Parechoviruses, Haemophilus influenzae, Listeria monocytogenes, Streptococcus pneumoniae, Neisseria meningitidis, Streptococcus agalactiae, Escherichia coli K1, Cryptococcus gattii/neoformans in cerebrospinal fluid samples were investigated using the Meningitis/Encephalitis RT-qPCR MX-17 Panel (RT-qPCR MX-17S Panel, Bio-Speedy®, Bioeksen, Türkiye) multiplex PCR kit. …”
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宁夏野生岩羊PPRV全基因组测定与系统进化分析 by 阚龙飞, 孟宪踊, 闫飞虎, 李元果, 王铁成, 徐钰, 初冬, 王卫东, 李岳城, 赵永坤, 高玉伟, 冯娜, 夏咸柱

“…为探究宁夏野生岩羊（<italic>Pseudois nayaur</italic>）小反刍兽疫病毒（Peste des petits ruminants virus，PPRV）的分子遗传特征，根据GenBank公布的PPRV基因组序列设计并合成13对全基因组扩增引物，通过RT-PCR和DNA测序及拼接获取毒株（wild-bharal/China-NXYH/2021株）全基因组序列，借助DNASTAR和MEGA 7.0软件进行序列分析。…”
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