日本血吸虫(大陆株)成虫基因表达谱的研究 by 吴忠道, 余新炳, 徐　劲, 李　焱, 李晖婷, 周俊梅, 包俊英, 卞国武, 郑亦男, 邵　筱, 彭寨玉

“…已克隆日本血吸虫精氨酸酶基因、Y-盒结合蛋白基因和抗凋亡-1 因子3 个新基因的 全长cDNA, 其GenBank 的登录号分别为AF402615 、AF367371 和AF333765 。…”
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TMEM101 expression and its impact on immune cell infiltration and prognosis in hepatocellular carcinoma by Lingyun Kuang, Yilin Pang, Quangang Fang

“…Gene set enrichment analysis (GSEA) revealed a correlation between TMEM101 and the cell cycle, DNA replication, and repair signaling pathways, which were differentially enriched in the TMEM101 high expression phenotype. …”
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Metatranscriptomic time series insight into antibiotic resistance genes and mobile genetic elements in wastewater systems under antibiotic selective pressure by An-Dong Li, Yuanfang Chen, Lei Han, Ye Li, Ming Xu, Baoli Zhu

“…The phylogenetic composition and ARG profiles at the DNA level remained stable. At the transcriptional level, significant upregulation of a class A beta-lactamase (P14171 gene) was observed. …”
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Exploration of different quantitative polymerase chain reaction-based genotyping methods to distinguish Apcmin/+ mice from wildtype mice. by Yuting Sun, Tingyu Zhou, Silin Ye, Effie Yin Tung Lau, Yao Zeng, Jessie Qiaoyi Liang

“…Dye-based qPCR and melting curve assays exhibited distinct dissociation patterns that differentiated between synthesised wildtype (TT) and heterozygous mutant (TA) DNA and between TT and TA genotype mice based on analysis of tissue samples. …”
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Association of Prehypertension with Renin Angiotensin System: A Cross-Sectional Study on Tribal Population of Northern India by Vani Kandpal, Mohinder Pal Sachdeva, Kallur Nava Saraswathy

“…The blood sample was collected for lipid and genetic analysis. DNA extraction and genotyping of five genetic markers of RAS-related pathway were performed. …”
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Detection of Hg2+ Using a Dual-Mode Biosensing Probe Constructed Using Ratiometric Fluorescent Copper Nanoclusters@Zirconia Metal-Organic Framework/N-Methyl Mesoporphyrin IX and Co... by Shikha Jain, Monika Nehra, Neeraj Dilbaghi, Ganga Ram Chaudhary, Sandeep Kumar

“…In the presence of Hg2+, dabcyl conjugated complementary DNA with T–T mismatches form the stable duplex with the CuNCs@Zr-MOF@G-quadruplex structure through T–Hg2+–T base pairing. …”
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小反刍兽疫LAMP反应结果可视化检测方法比较研究 by 索婧媛, 郑茜之, 王博, 刘学东

“…根据目前已经存在的判定LAMP结果的可视化方法，以可能对野生小反刍动物造成威胁的小反刍兽疫病毒（Peste des petits ruminants virus，PPRV）cDNA为检测对象，选择合适的引物组，比较评估均可在日光或紫外光下区分阴阳性结果的SYBR Green I、SYBR Safe Stain和羟基萘酚蓝（hydroxy naphthol blue，HNB）3种指示剂方法的适用性与灵敏度。…”
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蛋白酪氨酸磷酸酯酶4A2基因的克隆、表达及活性鉴定 by 程超, 郭爱林, 巫国勇, 吴伟康, 罗红鹤, 钟佛添

“…【方法】用RT-PCR技术,从肝癌细胞系HepG2的总RNA中,获得编码PTP4A2基因功能片段的DNA。测序后,通过酶切亚克隆至表达载体pGEX-4T-2,构建重组表达载体,并导入大肠杆菌E.coliBL21中,IPTG诱导表达重组的GST融合蛋白。…”
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The knowledge mapping of traditional Chinese medicine for hepatocellular carcinoma: A bibliometric study by Wenya Pei, Boyu Jiao, Zexiong Chen, Jingchun Zeng, Yancheng Fu, Zhanmou Liang, Baoguo Sun, Jingwen Ruan, Shijun Zhang

“…The analysis indicated that traditional Chinese medicine may enhance immunity and regulate the local tumor microenvironment through mechanisms involving DNA damage, cell cycle arrest, and apoptosis by signaling pathways. …”
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Mitochondrial genome insights into the phylogenetics and biogeographic evolution of snow trout (Cyprinidae, Schizothorax) in the Tien Shan Mountains by Akbarjon Rozimov, Yufan Wang, Min Wang, Ming Zou, Jobir Sobirov, Erkin Karimov, Bakhtiyor Kholmatov, Jörg Freyhof, Sirojiddin Namozov, Chongnv Wang, Xinxin Li, Baocheng Guo

“…We classified Schizothorax sp. as a valid independent species based on comprehensive phylogenetic trees and DNA barcode genetic distance. The dramatic uplift of the Tien Shan Mountains during the Late Miocene to the Pliocene, followed by periods of isolation on its eastern and western flanks, has driven extensive speciation, contributing to the rich diversity observed today. …”
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Safety, Immunogenicity, and Efficacy of Cytomegalovirus Vaccines: A Systematic Review of Randomized Controlled Trials by Manuela Chiavarini, Anita Genga, Giorgia Maria Ricciotti, Marcello Mario D’Errico, Pamela Barbadoro

“…<b>Results</b>: Several vaccine candidates have shown encouraging results in terms of safety and specific immune responses, notably adjuvanted gB vaccines and DNA vaccines targeting gB and pp65. The results were divided into RCTs on healthy individuals and those on transplant recipients, because the CMV-specific immune response to a vaccine is complex and varies depending not only on the type of vaccine, but also on the immunological status of the individual. …”
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Integrating multiomics analysis and machine learning to refine the molecular subtyping and prognostic analysis of stomach adenocarcinoma by Miaodong Wang, Qin He, Zeshan Chen, Yijue Qin

“…We downloaded the multiomics data of STAD patients in The Cancer Genome Atlas (TCGA)-STAD cohort, which included mRNA, microRNA, long non-coding RNA, somatic mutation, and DNA methylation data, from the sxdyc website. We synthesized the multiomics data of patients with STAD using 10 clustering methods, construct a consensus machine learning-driven signature (CMLS)-related prognostic models by combining 10 machine learning methods, and evaluated the prognosis models using the C-index. …”
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Genetic diversity of kaffir sorghum accessions from the VIR collection in kafirin-encoding loci by N. V. Alpatieva, I. N. Anisimova, M. K. Ryazanova, V. V. Vasipov, R. A. Abdullaev, O. I. Romanova, E. E. Radchenko

“…Due to the unique structure of endosperm storage proteins, kafirins, adding sorghum flour to dough is promising for producing dietetic nutrition components. Employing polymorphic DNA markers to study the diversity of kaffir sorghum accessions from the VIR collection as potential donors of biological and morphological traits in their grain is relevant for the development of sterile lines and sterility maintainers.Materials and methods. …”
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The Inhibitory Effects of Alpha 1 Antitrypsin on Endosomal TLR Signaling Pathways by Ahmed S. Elshikha, Georges Abboud, Rigena Avdiaj, Laurence Morel, Sihong Song

“…The proteolytic processing of these receptors in the endolysosome is required for signaling in response to DNA and single-stranded RNA, respectively. Targeting this proteolytic processing may represent a novel strategy to inhibit TLR-mediated pathogenesis. …”
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Toxicologic Assessment of a Commercial Decolorized Whole Leaf Aloe Vera Juice, Lily of the Desert Filtered Whole Leaf Juice with Aloesorb by Inder Sehgal, Wallace D. Winters, Michael Scott, Andrew David, Glenn Gillis, Thaya Stoufflet, Anand Nair, Konstantine Kousoulas

“…We found this DCWL aloe vera juice to be nongenotoxic in histidine reversion and DNA repair assays. Following acute administration, mice exhibited no adverse signs at 3- or 14-day evaluation periods. …”
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中国南方地区人群ＦＣＧＲ２Ａ基因多态性与强直性脊柱炎的相关性

“…【方法】 共纳入３５０例ＡＳ患者及２９５例健康志愿者，采用盐析法全血中抽提样本基因组ＤＮＡ，分别在患者及健康志愿者中随机抽取５８例病人和９０例对照者，采用外显子测序法筛选ＦＣＧＲ２Ａ基因单核苷酸多态性（ＳＮＰ），然后针对筛选出来的ＳＮＰ 在剩余的２９２例患者及２０５例健康志愿者中采用飞行质谱方法进行验证。…”
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Improvement of Post‐Thaw Quality and In Vivo Fertility of Simmental Bull Spermatozoa Using Ferulic Acid by Mobin Afsar, Ali Soleimanzadeh, Amir Khaki, Esmail Ayen

“…It also increased GPx and TAC levels, reducing MDA and DNA damage after freezing. The addition of FA did not affect SOD values. …”
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The Possible Role of TLR2 in Chronic Hepatitis B Patients with Precore Mutation by Malihe Moradzadeh, Sirous Tayebi, Hossein Poustchi, Kourosh Sayehmiri, Parisa Shahnazari, Elnaz Naderi, Ghodratollah Montazeri, Ashraf Mohamadkhani

“…Fifty-one patients with chronic hepatitis B, negative for HBeAg and detectable HBV DNA, were examined for the presence of mutations in pre-core region of HBV genome by direct sequencing. …”
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Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum by Han Zhao, Xia Zhou, Yu Song, Wenming Zhao, Zhongwu Sun, Jiajia Zhu, Yongqiang Yu

“…Abstract Background Gut microbiota dysbiosis is linked to Alzheimer’s disease (AD), but our understanding of the molecular and neuropathological bases underlying such association remains fragmentary. Methods Using 16S rDNA amplicon sequencing, untargeted metabolomics, and multi-modal magnetic resonance imaging, we examined group differences in gut microbiome, fecal metabolome, neuroimaging measures, and cognitive variables across 30 patients with AD, 75 individuals with mild cognitive impairment (MCI), and 61 healthy controls (HC). …”
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Association of polymorphism <i>TP53</i> Arg72Pro with radon-induced lung cancer in the Kazakh population by O. Bulgakova, A. Kussainova, A. Kakabayev, А. Kausbekova, R. Bersimbaev

“…The tumor suppressor gene TP53 is a key mediator of the DNA damage response cascade following cell exposure to ionizing radiation. …”
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