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4501
Spatiotemporal distribution patterns and assembly mechanisms of eukaryotic plankton communities in Liujiaxia Reservoir at the northeastern edge of the Tibetan Plateau
Published 2025-02-01“…This study provides valuable insight into the eukaryotic plankton community structure in the Liujiaxia Reservoir and reveals the complex relationships between plankton communities, environmental factors, and water quality.IMPORTANCEBased on 18S rDNA high-throughput sequencing, the spatiotemporal distribution patterns and assembly mechanisms of eukaryotic plankton communities were investigated. …”
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4502
Assessment of genetic diversity and phylogenetic relationships in Black Pied cattle in the Novosibirsk Region using microsatellite markers
Published 2022-01-01“…The goal of the present study was to analyze the genetic diversity in Black Pied cattle populations in the Novosibirsk Region and compare them with other Russian populations; to identify significantly divergent populations with a view to preserving them under the programs aimed at maintaining the genetic diversity of the domestic Black Pied breed. DNA samples from 4788 animals of the Black Pied breed from six breeding enterprises in the Novosibirsk Region have been studied using 11 microsatellite markers. …”
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4503
二代测序在子宫内膜癌分子分型的临床应用
Published 2023-03-01“…方法收集中山大学附属肿瘤医院经病理确诊的子宫内膜癌112例,均进行基于1 021个基因panel的杂交捕获二代测序检测,分析各分子亚型的分子变异谱及与临床病理特征之间的关系。结果DNA聚合酶<italic>ε</italic>(<italic>POLE</italic>)突变型8例(7.1%),错配修复功能缺陷型34例(30.4%),<italic>TP53</italic>突变型26例(23.2%),非特异性分子谱型44例(39.3%),4个亚型肿瘤突变负荷中位数分别为252.0、38.4、5.8及5.4 Muts/Mb。…”
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4504
Cecropin AD ameliorates pneumonia and intestinal injury in mice with mycoplasma pneumoniae by mediating gut microbiota
Published 2025-01-01“…Additionally, there was a notable upsurge in inflammatory factors within the affected tissues. 16 S rDNA sequencing revealed alterations in the colonic microbiota, including a decrease in the abundance of beneficial bacteria such as Corynebacterium_glutamicum and Candidatus_Saccharimonas, and an increase in the abundance of potential pathogens like Lachnospiraceae_NK4A136_group and Escherichia-Shigella. …”
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4505
DISCUSSIONS REGARDING A POSSIBLE GOVERNMENT GUARDIANSHIP CONTROL OVER ADMINISTRATIVE ACTS
Published 2024-05-01“…Considering this prestigious DNA inherited by the Government, combined with the fundamental role played by this essential administrative authority in executing and organising the activities of all public institutions in Romania, it follows that it assumes a responsibility for coordination and administrative patronage over all state authorities, regardless of the level at which they operate, whether at the central or local level, and regardless of their intrinsic functionality. …”
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4506
AMPD1 and MTHFR genes are not associated with calcium levels in rheumatoid arthritis patients with methotrexate therapy in Indonesia
Published 2025-01-01“…The inclusion criteria were patients diagnosed with RA, aged 18–59 years, and receiving MTX therapy for ≥ 6 months. DNA was isolated and then amplified using Polymerase Chain Reaction (PCR), and genotyping was performed with Sanger sequencing. …”
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4507
APOBEC3C‐mediated NF‐κB activation enhances clear cell renal cell carcinoma progression
Published 2025-01-01“…Here, we unveil that the enhanced expression of the RNA‐binding protein DNA dC → dU‐editing enzyme APOBEC‐3C (APOBEC3C; also known as A3C) in ccRCC tissue and ccRCC‐derived cell lines serves as a catalyst for tumor growth by amplifying nuclear factor‐kappa B (NF‐κB) activity. …”
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4508
Atypical conjunctival sporotrichosis secondary to Mooren’s ulcer: a case report
Published 2025-01-01“…Microbiological testing (DNA) confirmed Sporothrix schenckii as the pathogen. …”
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4509
Gas chromatography-mass spectrometry in the taxonomy of Miscanthus
Published 2020-01-01“…The results of chemotaxonomic analysis mostly matched those of DNA sequencing of a fragment of the plastid genome, which, moreover, allowed us to identify the species nature of the maternal plants used to obtain these hybrids. …”
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4510
Relationship of smokeless tobacco uses in the perspective of oral cancer: A global burden
Published 2024-06-01“…These substances exert genotoxic effects, inducing DNA damage, and disrupting cellular homeostasis within the oral mucosa. …”
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4511
In the Plots of Neoliberalism: the Impact of AirBnb on Hotel Industry and the Real Estate Market in São Paulo and Rio de Janeiro, Brazil
Published 2024-12-01“…The data about AirBnb was obtained from the AirDna Platform including the whole years of 2021, 2022, 2023 and January 2024, and concerning the real estate market in both cities, the main data source was SECOVI, a private entity that represents the economic category of real estate purchase, sale, rental and management companies. …”
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4512
Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives
Published 2024-12-01“…<i>Fn</i> engages in pancreatic tumorigenesis and metastasis through multifaceted mechanisms, including immune response modulation, virulence factors, control of cell proliferation, intestinal metabolite interactions, DNA damage, and epithelial–mesenchymal transition. …”
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4513
Adiponectin Gene Polymorphisms and Possible Susceptibility to Metabolic Syndrome among the Sudanese Population: A Case-Control Study
Published 2023-01-01“…The guanidine extraction procedure was used to extract genomic DNA from EDTA whole blood by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP); samples were genotyped for the polymorphisms (rs266729), (rs2241766), and (rs1501299). …”
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4514
Tumor-derived exosomal lncRNA-MIR193BHG promotes bone metastasis of breast cancer by targeting the miR-489-3p/DNMT3A signaling axis in osteoclasts
Published 2025-01-01“…LncRNA-MIR193BHG was delivered to osteoclasts via exosomes and promoted osteoclast formation and activity by targeting the miR-489-3p/DNA methyltransferase 3A (DNMT3A) signaling axis, thereby accelerating breast cancer-induced osteolysis. …”
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4515
Polymorphism of <i>Sdr</i> genes regulating seed dormancy in <i>Triticum persicum</i> Vav. and <i>Triticum aethiopicum</i> Jakubz.
Published 2020-01-01“…A deletion of 16 nucleotides was detected in the 3’-terminal region of the TraesCS2B02G215200 gene, located on the complementary DNA chain close to the 3’-end of the Sdr-B1 gene. …”
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4516
The Clinicopathological Characteristics and Prognoses of dMMR Gastric Adenocarcinoma Patients
Published 2021-01-01“…Few studies on the clinicopathological features and prognosis of DNA mismatch repair deficiency (dMMR) gastric cancer (GC) have been reported, and no clear conclusions have been drawn about the factors affecting the prognosis of dMMR GC. …”
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4517
Intermediate MCAD Deficiency Associated with a Novel Mutation of the ACADM Gene: c.1052C>T
Published 2015-01-01“…In this study, we report a Caucasian family with multiple MCADD individuals. DNA sequence analysis of the ACADM gene performed in this family revealed that two family members showing mild MCADD symptoms share the same novel change in exon 11, c.1052C>T, resulting in a threonine-to-isoleucine change. …”
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4518
L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer
Published 2025-01-01“…STAT3 upregulates the transcription of the key epithelial–mesenchymal transition transcription factor SNAIL in a DNA binding-independent manner. However, the mechanism by which STAT3 is recruited to the SNAIL promoter to upregulate its expression is still elusive. …”
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4519
Comparative Transcriptional Profiling of Two Contrasting Barley Genotypes under Salinity Stress during the Seedling Stage
Published 2013-01-01“…We compared changes in transcriptome between Hua 11 (a salt-tolerant genotype) and Hua 30 (a salt sensitive genotype) in response to salt stress at the seedling stage using barley cDNA microarrays. In total, 557 and 247 salt-responsive genes were expressed exclusively in the shoot and root tissue of the salt-tolerant genotype, respectively. …”
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4520
Fast and sensitive multivalent spatial pattern-recognition for circular RNA detection
Published 2024-12-01“…Here, we engineer an intelligent tetrahedral DNA framework (TDF) possessing precise spatial pattern-recognition properties with exceptional sensing speed and sensitivity for circRNAs. …”
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