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4381
Ecotope-Based Entomological Surveillance and Molecular Xenomonitoring of Multidrug Resistant Malaria Parasites in Anopheles Vectors
Published 2014-01-01“…This enables the EES to encompass mosquito collection and identification, salivary gland DNA extraction, Plasmodium- and species-specific identification, molecular marker-based PCR detection methods for putative drug resistance genes, and data management. …”
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4382
SSR-based evaluation of genetic diversity in populations of Agriophyllum squarrosum L. and Agriophyllum minus Fisch. & Mey. collected in South-East Kazakhstan
Published 2020-12-01“…The development of informative polymorphic DNA markers for poorly studied genera is an important step in population analyses of living organisms, including those that play very important ecological roles in harsh environments, such as desert and semi-desert area. …”
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4383
Multidisciplinary approach to functional somatic syndromes: study protocol for a population-based prospective cohort study
Published 2022-07-01“…Questionnaire-based diagnosis of FSSs are validated in a medical interview. Human DNA genotyping, microbial amplicon sequencing and urine analysis is under progress for genomics, microbiota and metabolomics profiling, respectively. …”
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4384
The SpxA1-TenA toxin-antitoxin system regulates epigenetic variations of Streptococcus pneumoniae by targeting protein synthesis.
Published 2024-12-01“…Human pathogen Streptococcus pneumoniae forms multiple epigenetically and phenotypically distinct intra-populations by invertase PsrA-driven inversions of DNA methyltransferase hsdS genes in the colony opacity-determinant (cod) locus. …”
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4385
Occurrence of the <i>FBF</i>7 fire blight resistance locus in accessions of apple wild species (<i>Malus</i> Mill.)
Published 2024-01-01“…Inter- and intraspecific polymorphism of the Malus genus was revealed for the analyzed resistance locus, as well as for individual DNA markers linked to the FBF7 QTL. The GE-8019 and AE10-375 markers flanking the FBF7 QTL were found in 42.0% of the studied genotypes. …”
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4386
Characterization of Integrons and Antimicrobial Resistance in Escherichia coli Sequence Type 131 Isolates
Published 2020-01-01“…The presence and characterization of class 1, 2, and 3 integrons, as well as promotor of gene cassettes and other antimicrobial resistance genes, were detected by PCR and DNA sequencing. Transfer of integrons was carried out using a broth culture mating method. …”
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4387
Elimination of Reactive Oxygen Species Formed by Chemotherapeutic Agent in Imatinib Resistant K562r Cell Line by Sweetgum Oil
Published 2024-07-01“…Cytotoxicity, ROS formation, DNA damage due to ROS, autophagy, and the expression of Atg4A, Atg5, LC3α/β proteins in cell lines were investigated. …”
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4388
Identification of Candidate Genes Associated with Meat Production of Aberdeen Angus Cattle
Published 2025-01-01“…This study investigated the relationships among a number of economically useful carcass traits (slaughter weight, meat yield, and meat marbling) with a group of SNPs that can act as DNA markers. Blood samples from Aberdeen Angus bulls (n = 260) were used as material for SNP genotyping. …”
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4389
Enhanced Engraftment of a Very Low-Dose Cord Blood Unit in an Adult Haemopoietic Transplant by Addition of Six Mismatched Viable Cord Units
Published 2010-01-01“…Early molecular remission of ALL was demonstrated using a novel PCR for a mitochondrial DNA mutation in the leukaemic clone. The cell dose of the matched cord was well below that recommended to engraft a 70 kg recipient. …”
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4390
A Nonsynonymous Single-nucleotide Polymorphism in SLC24A5 Regulates Feather Pigment Deposition in Chinese Yellow Quail
Published 2025-02-01“…The main objective of this study was to detect polymorphisms in the SLC24A5 gene of the Chinese yellow quail (Coturnix japonica) and analyze their effect on tyrosinase activity in skin tissue and melanin content in down feathers. The cDNA of the SLC24A5 gene was cloned by RT-PCR and subjected to Sanger sequencing. …”
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4391
<i>Triticum durum</i> Desf. is a valuable source for spring bread wheat genetic diversity enhancement
Published 2023-10-01“…Evaluation of these introgressive lines included phytopathological, phenological, genetic, and breadmaking analyses carried out with conventional methods both under open-air and laboratory conditions. Seventeen DNA markers were used to identify genes for resistance to Puccinia triticina Erikss. f. sp. tritici in the lines. …”
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4392
Silver single atoms and nanoparticles on floatable monolithic photocatalysts for synergistic solar water disinfection
Published 2025-01-01“…The photothermal effect of the plasmonic Ag nanoparticles reduces the bacterial resistance to ROS and impairs DNA repair capabilities. Under sunlight irradiation, the synergistic effect of Ag single atoms and nanoparticles enables 4.0 cm2 AgSA+NP/ZIF to achieve over 6.0 log inactivation (99.9999%) for the stress-resistant Escherichia coli (E. coli) in oligotrophic surface water within 30 min. …”
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4393
慢性HBV感染者经长期核苷(酸)类似物治疗获HBsAg 阴转停药后的疗效
Published 2016-01-01“…77.8%?87.5%?84.6%?100%;HBV DNA不可测率?HBeAg阴转率?HBeAg/HBeAb转换率及HBsAg阴转率各时间点全部为100%;HBsAg/HBsAb转换率各时间点分别为:42.9%?…”
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4394
Hypermethylation of the PRKCZ Gene in Type 2 Diabetes Mellitus
Published 2013-01-01“…The subjects were first divided into two groups: the T2DM group and the normal control (NC) group. Next, methylated DNA immunoprecipitation chip (MeDIP-chip) was used for detection. …”
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4395
Study on Seroprevalence and Leptospiral Antibody Distribution Among Livestock Breeders and Farmers in Golestan Province
Published 2024-11-01“…Methods Seventy samples of serum collected from farmers and ranchers suspected of leptospirosis were examined using an ELISA method for surveying Immunoglobulin M (IgM) anti‐leptospiria. Also from samples, DNA was extracted and PCR was performed using by primers for 16s rRNA. …”
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4396
The Role of NF-κB/MIR155HG in Regulating the Stemness and Radioresistance in Breast Cancer Stem Cells
Published 2025-01-01“…MIR155HG expression was manipulated in cells, followed by an assessment of stemness, DNA damage repair, apoptosis, cell cycle, and the Wnt signaling pathway under radiation conditions. …”
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4397
Review of the potential of bioactive compounds in seaweed to reduce histamine formation in fish and fish products
Published 2025-01-01“…The bioactive compounds considered, such as flavonoids, alkaloids, terpenes, and phenolic acids, exhibit their antibacterial effects through various mechanisms, including the inhibition of DNA and RNA synthesis, disruption of cytoplasmic and cell membranes, and inhibition of enzymes by reacting with sulfhydryl groups on proteins. …”
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4398
Characterization of Pathogenic Bacteria Isolated from Sudanese Banknotes and Determination of Their Resistance Profile
Published 2018-01-01“…Genotypic identification was carried out using PCR and 16S rDNA sequencing. Antibiotic resistance genes of some isolates were detected using PCR technique. …”
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4399
Synthesis of Novel VO(II)-Perimidine Complexes: Spectral, Computational, and Antitumor Studies
Published 2018-01-01“…The binding efficiency of ligands towards CT-DNA was tested. Binding constant (Kb) values are in agreement with the electron-drawing character of the p-substituent which offers high Kb values. …”
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4400
Antibacterial and Antioxidant Activities of Triterpenoids and Cyclic 1,7-Diarylheptanoids from the Stem Bark of Myrica salicifolia: A Combined Experimental and Computational Study
Published 2024-01-01“…The lowest binding affinity for compound 7 was found to be −7.26 to −10.35 kcal/mol against PqsA protein of P. aeruginosa, pyruvate kinase (PK) enzyme of S. aureus, LuxS protein of S. pyogenes, and DNA gyrase B of E. coli, which showed better binding affinity compared to the standard drug ampicillin (−7.36 to −8.03 kcal/mol) and ciprofloxacin (−6.19 to −6.83 kcal/mol). …”
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