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4081
Association of Androgen-Receptor Gene Mutations with the Copy Number of Androgen-Receptor Silk Protein A Complex and Glutathione-S-Transferases T1 and M1 in Prostate Cancer Patient...
Published 2023-01-01“…Fasting peripheral venous blood was collected, whole blood genomic DNA was extracted, and AR gene-receptor genotype was detected by a high-resolution melting curve analysis detection technology. …”
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4082
Biological Characteristics and Whole Genome Analysis of vB_VpP_3, a Bacteriophage against Multi-drug Resistant Vibrio parahaemolyticus
Published 2024-12-01“…Its genome was double-stranded linear DNA with a total length of 42 459 bp and a total GC content of 46.87% without any virulence or drug resistance genes. …”
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4083
Earthworm (Oligochaeta, Lumbricidae) intraspecific genetic variation and polyploidy
Published 2024-09-01“…In some cases, a single species may exhibit significant morphological variation, contain several races of different ploidy, and harbor multiple genetic lineages that display significant divergence in both nuclear and mitochondrial DNA. However, the relationship between ploidy races and genetic lineages in earthworms remains largely unexplored. …”
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4084
Synergism of d-limonene and temozolomide on migratory and apoptotic behaviors of human glioblastoma cell lines
Published 2024-09-01“…Methods: The effects of the combined treatment of DL and TMZ were assessed on various cellular aspects, including cell viability, anchorage-independent cell growth, and DNA damage. Furthermore, the influence of this combination on cell cycle progression, cell migration, and cell death was also investigated. …”
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4085
Molecular basis and genetics of hypohidrotic ectodermal dysplasias
Published 2023-11-01“…The overall prevalence of ectodermal dysplasia remains precisely unknown not only in Russia, but also in the world, nor is known the contribution of individual genes to its structure. This complicates the DNA diagnosis establishment of this disease due to the lack of an accurate diagnostic algorithm and a universal cost-effective method of analysis. …”
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4086
Effects of Colchicine and <sup>60</sup>Co-γ Radiation Treatments on the Leaf Size and Fruit Quality of Kiwifruit ‘Donghong’
Published 2025-01-01“…And, except for the 0.4c mutant, all other mutant materials exhibited significant genetic changes at the DNA level.…”
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4087
The Alpaca Melanocortin 1 Receptor: Gene Mutations, Transcripts, and Relative Levels of Expression in Ventral Skin Biopsies
Published 2015-01-01“…The objectives of the present study were to characterize the MC1R gene, its transcripts and the single nucleotide polymorphisms (SNPs) associated with coat color in alpaca. Full length cDNA amplification revealed the presence of two transcripts, named as F1 and F2, differing only in the length of their 5′-terminal untranslated region (UTR) sequences and presenting a color specific expression. …”
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4088
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4089
Viroids and Retrozymes: Plant Circular RNAs Capable of Autonomous Replication
Published 2024-12-01“…The most studied regulatory mechanisms involving circRNAs are acting as miRNA sponges, forming R-loops with genomic DNA, and encoding functional proteins. In addition to circRNAs generated by back-splicing, two types of circRNAs capable of autonomous RNA-RNA replication and systemic transport have been described in plants: viroids, which are infectious RNAs that cause a number of plant diseases, and retrozymes, which are transcripts of retrotransposon genomic loci that are capable of circularization due to ribozymes. …”
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4090
Efficacy of CLT4A variants as immunoregulatory molecules among Vitiligo patients in Saudi Arabia
Published 2025-02-01“…The recruitment was based on the sample size calculation and based on it, we have recruited 300 Saudi individuals who were evenly divided into vitiligo cases and controls. Extracted genomic DNA was utilized to amplify rs231775 and rs3087243 SNPs in the CTLA4 gene, which were subsequently digested and verified using Sanger sequencing. …”
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4091
Inhibitory Substances Produced by Native Lactobacillus plantarum UTNCys5-4 Control Microbial Population Growth in Meat
Published 2019-01-01“…The Cys5-4 peptides exerted their bacteriolytic mode of action inducing damage in the cell membrane of the target bacteria, allowing the leaching of DNA/RNA content. The results indicate that coating meat with CFS containing Cys5-4 is a promising approach to protect against further contamination by microorganism spoilage, as well as an alternative for increasing the shelf life of raw meat.…”
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4092
Epidemiology of Liver Cancer in Europe
Published 2000-01-01“…New laboratory techniques and biological markers such as polymerase chain reaction detection of HBV DNA and HCV RNA, as well as specific mutations related to LC, may help to provide quantitative estimates of the risk related to each these factors.…”
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4093
Comparison of baseline global gene expression profiles of prostate cancer cell lines LNCaP and DU145
Published 2024-12-01“…Methods LNCaP and DU145 cell lines were cultured under normal conditions, followed by RNA extraction, cDNA conversion, library preparation, and RNA sequencing using the Illumina NovaSeq platform. …”
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4094
Serological and Molecular Evidence of Q Fever in Domestic Ruminants in Bangladesh
Published 2016-01-01“…Randomly collected 111 bulk milk and 94 sera samples of cattle, sheep, and goats were tested by indirect ELISA (iELISA). DNA extracted from 23 aborted fetal membranes was analyzed by real time (rt) PCR. …”
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4095
Characterization of Malignant Melanoma Using Vibrational Spectroscopy
Published 2005-01-01“…The comparative analysis of various parameters calculated from the spectral data of the normal epidermis and the abnormal regions showed that the changes in the nucleic acids was a significant indicator of the abnormal nature of the tissues. The RNA/DNA ratio was decreased in case of both melanoma and nevus compared to the epidermis. …”
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4096
Antibody Levels in Ethiopian Children Five Years after Vaccination with Two Different Doses of Hepatitis B Vaccine: Is There a Need for Booster Vaccine?
Published 1998-01-01“…Both 10 and 20 µg doses of hepatitis B rDNA yeast vaccine were equally immunogenic and protective against HBV infection for at least five years despite marked reduction of mean antibody levels and geometric mean titres, with 11% of the vaccinees showing antibodies below the protective level. …”
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4097
Posttransplantation Lymphoproliferative Disease Treated by Retransplantation
Published 2020-01-01“…The conditioning used was thiotepa/busulfan/fludarabin with a single dose of cyclophosphamide after transplant as graft-versus-host disease (GVHD) prophylaxis. The EBV DNA levels fell when conditioning was started, and have been undetectable since day +15 and remained so till 18 months after transplantation. …”
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4098
lncRNA PAPPA-AS1 Induces the Development of Hypertrophic Scar by Upregulating TLR4 through Interacting with TAF15
Published 2021-01-01“…It was accompanied by the alleviated pathological state in the HTS tissues, which were significantly reversed by cotransfecting with the pcDNA3.1-TLR4 vector. Positive correlation and interaction were observed between PAPPA-AS1 and TAF15 and between TAF15 and the promoter of TLR4, respectively. …”
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4099
Field study on the suitability of oral fluid samples for monitoring of Lawsonia intracellularis and Brachyspira hyodysenteriae by multiplex qPCR under field conditions
Published 2025-01-01“…Results Cohen´s Kappa analysis revealed a substantial agreement between oral fluids and pooled fecal samples on pen level (Cohen´s Kappa: 0.745; p < 0.001). DNA-loads of L. intracellularis were tendentially higher (p = 0.053) in pooled fecal samples than in the corresponding OFs. …”
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4100
Correlating disordered activation domain ensembles with gene expression levels
Published 2025-03-01“…Transcription factor proteins bind to specific DNA promoter sequences and initiate gene transcription. …”
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