Chromosome-scale telomere to telomere genome assembly of common crystalwort (Riccia sorocarpa Bisch.) by Katarzyna Krawczyk, Joanna Szablińska-Piernik, Łukasz Paukszto, Mateusz Maździarz, Paweł Sulima, Jerzy Andrzej Przyborowski, Monika Szczecińska, Jakub Sawicki

“…Moreover, collinearity of Marchantiales was analyzed as well as gene family evolution and DNA methylation profile. The availability of this genome, which is the second telomere-to-telomere liverwort assembly, opens up new avenues for in-depth analysis of R. sorocarpa genetic diversity and genomic characteristics.…”
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Influence of leptin administration to pregnant mice on fetal gene expression and adaptation to sweet and fatty food in adult offspring of different sexes by E. I. Denisova, E. N. Makarova

“…The results suggest that the influence of maternal leptin on the expression of genes encoding growth factors and DNA methyltransferases in the fetal liver may mediate its programming effect on offspring metabolic phenotypes.…”
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PHYLOGENETIC RELATIONSHIPS AMONG POPULATIONS OF THE RED VOLE MYODES (= CLETHRIONOMYS) RUTILUS PALLAS, 1779 IN THE NORTHERN PRIOKHOTYE AND KOLYMA REGIONS by V. V. Pereverzeva, A. A. Primak, E. A. Dubinin

“…The goal of the work was the determination of phylogenetic relationships in red vole associations of the Northern Priokhotye and Kolyma regions on the base of analysis of partial mtDNA cytb gene sequence polymorphism in some Myodes (Сlethrionomys) rutilus populations of Northeastern Asia and Alaska. …”
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Free radicals and their impact on health and antioxidant defenses: a review by Nisansala Chandimali, Seon Gyeong Bak, Eun Hyun Park, Hyung-Jin Lim, Yeong-Seon Won, Eun-Kyung Kim, Sang-Ik Park, Seung Jae Lee

“…Oxidative stress results in the damage of critical biomolecules like DNA, proteins, and lipids, contributing to the pathogenesis of various diseases. …”
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Cinnamaldehyde impacts key cellular signaling pathways for induction of programmed cell death in high-grade and low-grade human glioma cells by Yoo Na Kim, Ketki Patil, S. Balakrishna Pai

“…However, TMZ can cause damage to DNA if taken for prolonged period. This warrants the discovery of drugs that would potentially elicit less adverse side effects while maintaining anticancer activity. …”
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The Extracts of Some Marine Invertebrates and Algae Collected off the Coast Waters of Vietnam Induce the Inhibitory Effects on the Activator Protein-1 Transcriptional Activity in J... by S. N. Fedorov, V. B. Krasokhin, L. K. Shubina, S. A. Dyshlovoy, N. H. Nam, C. V. Minh

“…The inhibitory effects of the extracts of Vietnamese marine organisms in relation to the AP-1 transcriptional activity were examined by the luciferase method using JB6 Cl41 cells stably expressing a luciferase reporter gene controlled by AP-1 DNA binding sequence. As was found, 71 species of marine sponges out of 148 species studied contain inhibitors of the AP-1 transcriptional activity. …”
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Application of PS2M Aptamer as Receptor Layer for Electrochemical Detection of Lead Ions by Izabela Zaras, Olga Kujawa, Marcin Olszewski, Marta Jarczewska

“…In most cases, thrombin binding aptamer (TBA) was utilized; however, there are more examples of DNA aptamers which could also serve that purpose. …”
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The Absence of Nrf2 Enhances NF-B-Dependent Inflammation following Scratch Injury in Mouse Primary Cultured Astrocytes by Hao Pan, Handong Wang, Xiaoliang Wang, Lin Zhu, Lei Mao

“…Primary cultured astrocytes were scratched to mimic the traumatic injury in vitro. Then the DNA-binding activity of NF-κB was evaluated by EMSA. …”
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Effect of H2O2 induced oxidative stress on volatile organic compounds in differentiated 3T3-L1 cells by Adebowale Samuel Oyerinde, Vaithinathan Selvaraju, Melissa Boersma, Jeganathan Ramesh Babu, Thangiah Geetha

“…Reactive oxygen species (ROS) can interact with biological components, triggering processes like protein oxidation, lipid peroxidation, or DNA damage, resulting in the generation of several volatile organic compounds (VOCs). …”
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Using Genome-Wide SNP Discovery and Genotyping to Reveal the Main Source of Population Differentiation in Nothofagus dombeyi (Mirb.) Oerst. in Chile by Rodrigo Hasbún, Jorge González, Carolina Iturra, Glenda Fuentes, Diego Alarcón, Eduardo Ruiz

“…Postglacial history has been studied with chloroplast DNA and evolutionary forces shaping genetic variation patterns have been analysed with isozymes but fine-scale genetic diversity studies are needed. …”
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Programmed Cell Death, Proliferating Cell Nuclear Antigen and p53 Expression in Mouse Colon Mucosa during Diet-Induced Tumorigenesis by Mauro Risio, Ivana Sarotto, Francesco Paolo Rossini, Harold Newmark, Kan Yang, Martin Lipkin

“…In order to evaluate the roles both of cell proliferation and programmed cell death (PCD) in WD‐induced tumorigenesis, immunohistochemical detection of proliferating nuclear antigen (PCNA), in situ end labeling (TUNEL) of DNA breaks, and p53 protein were carried out in mouse colonic mucosa during prolonged feeding of two WDs. …”
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Decoding the general role of tRNA queuosine modification in eukaryotes by Jorge Díaz-Rullo, Luis González-Moreno, Araceli Del Arco, José Eduardo González-Pastor

“…Here, through bioinformatics analysis of representative eukaryotic genomes we have predicted: i) the genes enriched in NAU codons, whose translation would be affected by tRNA Q-modification (Q-genes); and ii) the specific biological processes of each organism enriched in Q-genes, which generally in eukaryotes would be related to ubiquitination, phosphatidylinositol metabolism, splicing, DNA repair or cell cycle. These bioinformatics results provide evidence to support for the first time in eukaryotes that the wide diversity of phenotypes associated with tRNA Q-modification previously described in various species would directly depend on the control of Q-genes translation, and would allow prediction of unknown Q-dependent processes, such as Akt activation and p53 expression, which we have tested in human cancer cells. …”
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Diversity and Species Composition of Midgut Symbiotic Bacteria in Culex quinquefasciatus Mosquitoes in Gampaha District, Sri Lanka by Randi Hathnagoda, Pinidi Gunathilake, Thilini Buddhinee, Pabasara Welgama, Hasini Gunarathna, Harshani Perera, Koshila Ranasinghe

“…Subsequently, the most abundant bacterial families were subjected to DNA extraction, PCR amplification, and gene sequencing for species identification. …”
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Mycobacterium tuberculosis Lineage Distribution Using Whole-Genome Sequencing and Bedaquiline, Clofazimine, and Linezolid Phenotypic Profiles among Rifampicin-Resistant Isolates fr... by Andriansjah Rukmana, Cynthia Gozali, Linda Erlina

“…All isolates were tested for M. tuberculosis and rifampicin resistance using Xpert MTB/RIF. The DNA genome of M. tuberculosis was freshly extracted from a Löwenstein–Jensen medium culture and then sequenced. …”
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Synthesis, Spectroscopic Characterization, and Biological Evaluation Studies of 5-Bromo-3-(((hydroxy-2-methylquinolin-7-yl)methylene)hydrazono)indolin-2-one and Its Metal (II) Comp... by Kuruba Siddappa, Nabiya Sultana Mayana

“…The Schiff base (BHMQMHI) and its metal complexes have been screened for their in vitro antibacterial and antifungal activities by minimum inhibitory concentration (MIC) method. The DNA cleavage activities of all the complexes were studied by agarose gel electrophoresis method. …”
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Molecular screening of rare cucurbit accessions for the presence of markers for genes and QTls controlling resistance to powdery mildew by E. N. Markova, F. A. Berensen, I. V. Gashkova, O. Yu. Antonova

“…Marker-assisted molecular breeding techniques make it possible to quickly identify necessary DNA fragments in order to find resistant and susceptible forms of donor plants. …”
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Unveiling promising sepsis biomarkers: a clinical perspective by Hong Zhang, Junpeng Zhao, Zhiping Wang, Mengxiang Huang, Zhonghua Tan, Feng Jiang, Yuhong Zhou, Linhua Wang, Mingbing Xiao

“…In recent years, new biomarkers, such as neutrophil extracellular traps, interleukin-6, histones, cell-free DNA and composite indicators, such as the systemic immune inflammation index,have been identified. …”
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“One Ring to Bind Them All”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles by Anton Granzhan, David Monchaud, Nicolas Saettel, Aurore Guédin, Jean-Louis Mergny, Marie-Paule Teulade-Fichou

“…These compounds are thus likely to create multiple contacts with the target that may be at the origin of their high selectivity, thereby suggesting that this class of macrocycles offers unique advantages for targeting G-quadruplex-DNA.…”
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Aweak phenotype associated with novel ABO*A allele variant c.106delinsGG by Sanmukh Ratilal Joshi, Glenda Millard, Mayuri Vekariya, Priya Radadiya, Manisha Rajapara, Hiren Dhanani, Gaurav Shastri, Prabhat Sharma, Brett Wilson, Yew-Wah Liew

“…The molecular sequencing was performed on DNA with enrichment library prep kit and a custom designed overlapping probe panel. …”
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Assessment of Damage to Nucleic Acids and Repair Machinery in Salmonella typhimurium Exposed to Chlorine by M. H. Phe, M. Hajj Chehade, H. Guilloteau, C. Merlin, J. C. Block

“…In this paper, we hypothesized that a successful disinfection is achieved only when the applied chlorine leads to both intracellular nucleic acid damage and strong alterations of the DNA repair machinery. Monitoring the SOS system responsiveness with a umuC'-‘lacZ reporter fusion, we found that the expression of this important cellular machinery was altered after the beginning of membrane permeabilization but prior to the total decline of both the cell culturability and the nucleic acid integrity as revealed by Sybr-II staining. …”
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