Technical Aspects of Laparoscopic Distal Pancreatectomy for Benign and Malignant Disease: Review of the Literature by T. de Rooij, R. Sitarz, O. R. Busch, M. G. Besselink, M. Abu Hilal

“…Distal pancreatectomy is the standard curative treatment for symptomatic benign, premalignant, and malignant disease of the pancreatic body and tail. …”
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Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa by Nell Hirt, Enzo Manchon, Qian Chen, Clara Delaroque, Aurelien Corneau, Patrice Hemon, Safaa Saker-Delye, Pauline Bataille, Jean-David Bouaziz, Emmanuelle Bourrat, Alain Hovnanian, Helene Le Buanec, Fawzi Aoudjit, Hicham El Costa, Nabila Jabrane-Ferrat, Reem Al-Daccak

“…By characterising the phenotype-endotype association in RDEB adults, our study lays the groundwork for translational interventions that could by lessening inflammation, alleviate the everlasting suffering of RDEB patients, while awaiting curative genetic therapies.…”
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Influential Factors and Synergies for Radiation-Gene Therapy on Cancer by Mei Lin, Junxing Huang, Yujuan Shi, Yanhong Xiao, Ting Guo

“…Based on the problems existing in radiation-gene therapy, many efforts have been devoted to the curative effect improvement of radiation-gene therapy by various means to increase radiation sensitivity or enhance target gene expression and the expression’s controllability. …”
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Faculty Profile Management System Using IRINS for the Analysis of Research Performance in the Field of Science and Technology by S. Thanuskodi, P. Kannan

“…Academic institutes and Research and Development organizations collect, curate, and organize research-related activities from various sources. …”
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Extensive Growth of an Anaplastic Meningioma by Hajrullah Ahmeti, Homajoun Maslehaty, Athanasios K. Petridis, Alexandros Doukas, Mehran Mahvash, Harald Barth, H. M. Mehdorn

“…A surgical procedure with the aim of complete tumor resection in a curative manner was not possible. Six months after the first operation, due to a new tumor progression, most extensive tumor resection was performed. …”
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Frequency of Missing TNM Stage Data for Adults With Intellectual or Developmental Disabilities in a Provincial Cancer Registry—A Brief Report by Kelly Biggs, Helene Ouellette‐Kuntz, Rebecca Griffiths, Rebecca Hansford, Julie Hallet, Christine Kelly, Kathleen Decker, David E. Dawe, Shahin Shooshtari, Marni Brownell, Donna Turner, Virginie Cobigo, Alyson Mahar

“…At the individual level, if stage data are not simply missing from the registry but reflect incomplete or absent diagnostic or staging procedures, this may represent barriers for adults with IDD in receiving curative treatment. At the population level, research using inaccurate or incomplete stage data may lead to unrepresentative health and social system policy decisions. …”
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High frequency CCR5 editing in human hematopoietic stem progenitor cells protects xenograft mice from HIV infection by Daniel T. Claiborne, Zachary Detwiler, Steffen S. Docken, Todd D. Borland, Deborah Cromer, Amanda Simkhovich, Youdiil Ophinni, Ken Okawa, Timothy Bateson, Tao Chen, Wesley Hudson, Radiana Trifonova, Miles P. Davenport, Tony W. Ho, Christian L. Boutwell, Todd M. Allen

“…These results raise the potential of using CRISPR/Cas9 to produce a curative autologous HSCT and bring us closer to the development of a cure for HIV infection.…”
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Clinical entity-aware domain adaptation in low resource setting for inflammatory bowel disease by Sumam Francis, Fernando Crema Garcia, Kanimozhi Uma, Willem Mestdagh, Bart De Moor, Marie-Francine Moens

“…In summary, we developed a comprehensive pipeline for clinical Dutch NER encompassing an efficient domain adaptation strategy with domain-aware masking and model fine-tuning enhancements, and an end-to-end entity extraction tool, significantly advancing medical record curation and clinical workflows.…”
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Slow and diverse: Upslope expansion of tree species since 1854 in the Bavarian Alps (Germany) detected by citizen science by Sabine Rösler, Michelangelo Olleck, Karl H. Mellert, Jörg Ewald

“…For nine of ten species with sufficient numbers of historical and citizen science observations, currently uppermost outpost occurrences were verified after data curation and subsampling. Tree species of montane (Sorbus aucuparia: 342 m, Abies alba: 324 m, Acer pseudoplatanus: 273 m, Fagus sylvatica: 141 m) and of lower subalpine distribution (Betula pubescens: 278 m, Picea abies: 55 m) climbed significantly, whereas species found at the high subalpine tree line ecotone ascended less (Pinus mugo: 21 m, Larix decidua: 13 m, Alnus alnobetula: 6 m) or even appeared to lose elevation (Pinus cembra: −57 m). …”
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Current Treatment Approaches to HCC with a Special Consideration to Transplantation by N. Bhardwaj, M. T. P. R. Perera, M. A. Silva

“…Additionally new techniques for organ preservation have increased the prospect of this potentially curative procedure being available for a greater number of patients.…”
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Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors: A State of the Art Review by Sven-Petter Haugvik, Knut Jørgen Labori, Bjørn Edwin, Øystein Mathisen, Ivar Prydz Gladhaug

“…Surgical resection is the only curative treatment and remains the cornerstone therapy for this patient group, even in patients with advanced disease. …”
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Alpha-Fetoprotein and Novel Tumor Biomarkers as Predictors of Hepatocellular Carcinoma Recurrence after Surgery: A Brilliant Star Raises Again by Quirino Lai, Fabio Melandro, Rafael S. Pinheiro, Andrea Donfrancesco, Bashir A. Fadel, Giovanni B. Levi Sandri, Massimo Rossi, Pasquale B. Berloco, Fabrizio M. Frattaroli

“…Starting from these considerations, these markers have been therefore routinely and successfully used as predictors of survival and HCC recurrence in patients treated with curative intent. All these markers have been largely used as predictors in patients treated with hepatic resection or locoregional therapies, mainly in Eastern countries. …”
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Global Gene Expression Profiling in PPAR-γ Agonist-Treated Kidneys in an Orthologous Rat Model of Human Autosomal Recessive Polycystic Kidney Disease by Daisuke Yoshihara, Masanori Kugita, Tamio Yamaguchi, Harold M. Aukema, Hiroki Kurahashi, Miwa Morita, Yoshiyuki Hiki, James P. Calvet, Darren P. Wallace, Takafumi Toyohara, Takaaki Abe, Shizuko Nagao

“…By Gene Set Enrichment Analysis of 30655 genes, 13 of the top 20 downregulated gene ontology biological process gene sets and six of the top 20 curated gene set canonical pathways identified to be downregulated by PIOtreatment were related to cell cycle and proliferation, including EGF, PDGF and JNK pathways. …”
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Metastatic Non-Small-Cell Lung Cancer in the Setting of Unilateral Agenesis of the Left Pulmonary Artery: A Case Report and Comprehensive Literature Review by John Agzarian, Jakub Kadlec, Lori Whitehead, Yaron Shargall

“…In the majority of these, anatomic lung resection (most commonly with pneumonectomy) was curative. We present the first reported case of ipsilateral metastatic non-small-cell lung cancer- (NSCLC-) associated UAPA in a 47-year-old patient with ventilator-dependent hypoxic respiratory failure and bronchorrhea, who had been lost to follow-up for 8 years. …”
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Phoenix dactylifera L. (date palm) fruit extracts and fractions exhibit anti-proliferative activity against human pancreatic cancer cell lines by Reem A. Al Alawi, Jörg D. Hoheisel, Mohamed Saiel Saeed Alhamdani, Younis Baqi

“…Hence, there is a pivotal need to find new effective preventive and curative treatments. In this study, extracted and fractions obtained from date palm (Phoenix dactylifera L.) fruit using ethyl acetate and n-butanol as solvents. …”
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Aggressive Angiomyxoma in Pregnancy: A Rare Condition, a Common Misdiagnosis by J. Sampaio, I. Sarmento-Gonçalves, D. Ramada, T. Amaro, P. Tiago-Silva

“…Wide surgical excision with tumor free margins is the basis of curative treatment. Adjuvant therapy may be necessary for residual or recurrent tumors. …”
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A Review of Complicated Cataract in Retinitis Pigmentosa: Pathogenesis and Cataract Surgery by Yingying Hong, Hongzhe Li, Yang Sun, Yinghong Ji

“…Despite the absence of curative pharmacologic treatment, phacoemulsification with intraocular lens implantation to deal with opacification in the lens is preferred due to the considerable visual outcomes. …”
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Longitudinal investigation of albumin-to-globulin ratio for human cancers demonstrates benefit in postoperative serial remeasurement by Zhenhui Li, Chunxia Li, Ruimin You, Yanli Li, Lizhu Liu, Hongjiang Pu, Ming Lei, Wenliang Li, Tao Zhang, Dingyun You

“…In this study, 2844 CRC patients, 2267 NSCLC patients and 507 HCC patients who underwent curative resection were included. Postoperative AGR was a prognostic factor independent to preoperative AGR, performing a L shaped relation with OS. …”
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Integrating transcriptomics, metabolomics, and network pharmacology to investigate multi-target effects of sporoderm-broken spores of Ganoderma lucidum on improving HFD-induced dia... by Lidan Hu, Lili Yu, Zhongkai Cao, Yue Wang, Caifeng Zhu, Yayu Li, Jiazhen Yin, Zhichao Ma, Xuelin He, Ying Zhang, Wunan Huang, Yuelin Guan, Yue Chen, Xue Li, Xiangjun Chen

“…Diabetes mellitus (DM) is a major metabolic disease endangering global health, with diabetic nephropathy (DN) as a primary complication lacking curative therapy. Sporoderm-broken spores of Ganoderma lucidum (GLP), an herbal medicine, has been used for the treatment of metabolic disorders. …”
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FusOn-pLM: a fusion oncoprotein-specific language model via adjusted rate masking by Sophia Vincoff, Shrey Goel, Kseniia Kholina, Rishab Pulugurta, Pranay Vure, Pranam Chatterjee

“…We introduce FusOn-pLM, a fine-tuned pLM trained on a newly curated, comprehensive set of fusion oncoprotein sequences, FusOn-DB. …”
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