Hepatocellular Carcinoma: Current Management and Future Development—Improved Outcomes with Surgical Resection by Yoji Kishi, Kiyoshi Hasegawa, Yasuhiko Sugawara, Norihiro Kokudo

“…A major problem is the high recurrence rate even after curative resection, especially in the remnant liver. …”
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Basal Cell Carcinoma of the Penis: A Case Report and Review of the Literature by R. J. Roewe, Matthew A. Uhlman, Nathan A. Bockholt, Amit Gupta

“…Fortunately, wide local excision of such lesions is generally curative. Fewer than 25 cases have been reported in the literature describing penile basal cell carcinoma. …”
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A Case of Stage I Vulvar Squamous Cell Carcinoma with Early Relapse and Rapid Disease Progression by Marta Peri, Antonino Grassadonia, Laura Iezzi, Patrizia Vici, Michele De Tursi, Clara Natoli, Nicola Tinari, Marinella Zilli

“…Locoregional surgery is often curative when the tumor is diagnosed at an early stage. …”
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Pneumoperitoneum, Retropneumoperitoneum, Pneumomediastinum, and Diffuse Subcutaneous Emphysema following Diagnostic Colonoscopy by Evangelos Falidas, Georgios Anyfantakis, Konstantinos Vlachos, Christina Goudeli, Boutzouvis Stavros, Constantinos Villias

“…Colonoscopy is a widely used diagnostic and curative procedure. Extraperitoneal perforation with pneumoretroperitoneum, pneumomediastinum and subcutaneous emphysema combined with intraperitoneal perforation is an extremely rare complication. …”
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Reframing the filter bubble through diverse scale effects in online music consumption by Dougal Shakespeare, Victor Chareyron, Camille Roth

“…Abstract The impact of platforms’ algorithmic curation devices on users’ consumption diversity has long since been the subject of debate in popular culture and academia alike. …”
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Late Endocrine Effects after Stem Cell Transplant in a Young Girl with Griscelli Syndrome by Shana R. Mencher, William V. Tamborlane, Anisha D. Patel

“…Type 2 GS is fatal due to severe immunodeficiency without curative stem cell transplant (SCT). Late endocrinopathies are quite common in other disorders after SCT. …”
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CAR T cells for treating autoimmune diseases by Dimitrios Mougiakakos, Ulrike Koehl, Stephan Fricke, Ulrich Blache, Sandy Tretbar

“…Currently, autoimmune disorders are largely treated by broad immunosuppressive agents and blocking antibodies, which can manage the diseases but often are not curative. Thus, there is an urgent need for advanced therapies for patients suffering from severe and refractory autoimmune diseases, and researchers have considered cell therapy as potentially curative approach for several decades. …”
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Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta. by Jennifer McIntyre, Alison Morrison, Kirsty Maitland, Duncan Berger, Daniel R G Price, Sam Dougan, Dionysis Grigoriadis, Alan Tracey, Nancy Holroyd, Katie Bull, Hannah Rose Vineer, Mike J Glover, Eric R Morgan, Alasdair J Nisbet, Tom N McNeilly, Yvonne Bartley, Neil Sargison, Dave Bartley, Matt Berriman, James A Cotton, Eileen Devaney, Roz Laing, Stephen R Doyle

“…Assembly using PacBio long-reads and Hi-C long-molecule scaffolding together with manual curation resulted in a 573 Mb assembly (N50 = 84 Mb, total scaffolds = 1,286) with five autosomal and one sex-linked chromosomal-scale scaffolds consistent with its karyotype. …”
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Preliminary Results of Hyperthermic Intraperitoneal Intraoperative Chemotherapy as an Adjuvant in Resectable Pancreatic Cancer by Antonios-Apostolos K. Tentes, Dimitrios Kyziridis, Stylianos Kakolyris, Nicolaos Pallas, Georgios Zorbas, Odysseas Korakianitis, Christos Mavroudis, Nicolaos Courcoutsakis, Panos Prasopoulos

“…Patients with pancreatic cancer undergoing potentially curative resection in combination with HIPEC may be offered a survival benefit. …”
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Clinical Presentation, Risk Factors, and Treatment Modalities of Hepatocellular Carcinoma: A Single Tertiary Care Center Experience by Abdulrahman A. Aljumah, Hadi Kuriry, Mohammed AlZunaitan, Mohammed Al Ghobain, Mohamed Al Muaikeel, Ashwaq Al Olayan, Fahad Azzumeea, Bader Almutairi, Abduljaleel AlAlwan, Hamdan AlGhamdi

“…HCC in Saudi Arabia is associated with high prevalence of HCV. Potentially curative therapies were underutilized in our patients. …”
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Colorectal Carcinoma with Extremely Low CA19-9 by Yutaka J. Kawamura, Aika Tokumitsu, Junichi Sasaki, Shingo Tsujinaka, Takafumi Maeda, Ken Mizogami, Fumio Konishi

“…Of these, 86 underwent surgery with curative intent. Serum levels of CA19-9 in patients who did not undergo curative resection (𝑁=12) and who developed recurrence (𝑁=10) were less than 2.0 U/mL in all occasions during followup. …”
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Interrupted time series datasets from studies investigating the impact of interventions or exposures in public health and social science: a data note by Simon L Turner, Elizabeth Korevaar, Amalia Karahalios, Andrew B Forbes, Joanne E McKenzie

“…Data description The repository includes 430 ITS datasets curated from the two empirical studies. The datasets are diverse in the populations, interruptions and outcomes examined, and are methodologically diverse in the outcome types, aggregation time intervals, number of timepoints and segments. …”
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Clinical Characteristics and Surgical Prognosis of Hepatocellular Carcinoma with Bile Duct Invasion by Ke-Wei Meng, Mei Dong, Wei-Guo Zhang, Qing-Xian Huang

“…Methods. 413 patients with HCC undergoing curative surgery were divided into two groups with (B+) and without BDI (B−). …”
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In Vivo Antiplasmodial Activity and Toxicological Analyses of the Ethanolic Leaf and Twig Extract of Faurea speciosa Welw. (Proteaceae) by Felix Ayisi, Caleb Nketia Mensah, Lawrence Sheringham Borquaye

“…The antiplasmodial effect against early infection, curative effect against established infection, and prophylactic effect against residual infection were studied in vivo in Plasmodium berghei-infected mice while the carrageenan-induced edema model in chicks was used for anti-inflammatory tests. …”
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Clinical Outcomes of Ileostomy Closure before Adjuvant Chemotherapy after Rectal Cancer Surgery: An Observational Study from a Chinese Center by Zhen Sun, Yufeng Zhao, Lu Liu, Jichao Qin

“…Temporary ileostomy closure before adjuvant chemotherapy following curative rectal cancer resection can achieve a clinical and oncological safety level equal to stoma closure during or after chemotherapy in selected patients.…”
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Cyclooxygenase-2 Expression Is a Predictive Marker for Late Recurrence in Colorectal Cancer by Sung Hoo Kim, Byung Kyu Ahn, Seung Sam Paik, Kang Hong Lee

“…Ninety-eight patients with recurrence in 376 CRC patients, who underwent curative surgery between January 1991 and August 2001, were retrospectively assessed. …”
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SURGICAL TECHNIQUES TO INCREASE RESECTABILITY IN LIVER METASTASIS by Orlando Jorge Martins Torres, Guido Torzilli, Marcelo Enne, Rinaldo Gonçalves, Eduardo de Santibanes, Timothy Pawlik, Rene Adam, Olivier Soubrane, Paulo Herman, Ricardo Lemos Cotta-Pereira

“…Many strategies have been developed to allow patients for surgical resection (percutaneous portal vein embolization, liver venous deprivation, parenchyma-sparing liver surgery, reverse strategy, associating liver partition and portal vein ligation for staged hepatectomy, and liver transplantation), the only form of disease control and curative treatment.…”
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Endoscopic Treatment of Early-stage Large Gastric Cancer and Closure with Hand-suturing Technique by Fatih Aslan, Serhat Özer, Orhun Çığ Taşkın

“…Endoscopic submucosal dissection (ESD), when indicated based on tumor size, stage, and histological characteristics, is a highly successful curative, minimally invasive, non-surgical endoscopic treatment option. …”
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Great Excavations: Methodological considerations arising after a major archaeological infrastructure project for the A14 Cambridge to Huntingdon Road Improvement Scheme by Alex Smith, Emma West, Stephen Sherlock, Kasia Gdaniec, David Bowsher

“…To deliver a more balanced methodological evaluation, perspectives from different project stakeholders are captured here: those of the client (National Highways and A14 IDT), principal archaeological contractor (MHI) and curator (Cambridgeshire Historic Environment Team; CHET).…”
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La conservation-restauration en spectacle : les dessous des chefs-d’œuvre révélés dans les expositions by Claire Casedas

“…These exhibitions allow to interest and explain to visitors the curators-restorators’ part in laboratories, when they are restoring and studying the cultural works. …”
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