A Case of Waterhouse-Friderichsen Syndrome Resulting from an Invasive Pneumococcal Infection in a Patient with a Hypoplastic Spleen by Kazumasa Emori, Nobuhiro Takeuchi, Junichi Soneda

“…The following day, blood cultures revealed the presence of Streptococcus pneumoniae. …”
Get full text

Periductal Mastitis: An Inflammatory Disease Related to Bacterial Infection and Consequent Immune Responses? by Lu Liu, Fei Zhou, Pin Wang, Lixiang Yu, Zhongbing Ma, Yuyang Li, Dezong Gao, Qiang Zhang, Liang Li, Zhigang Yu

“…To investigate the roles of bacterial infection and critical cytokines expression, 16S rRNA gene sequencing and bacterial culturing were conducted. We also measured the levels of interferon-γ, interleukin-12A, and interleukin-17A by semiquantitative immunohistochemistry method. …”
Get full text

Governing the boundary: between socio-environmental vulnerability and state capacity in Temajuk Village, Indonesia by Alfath Bagus Panuntun El Nur Indonesia, Defila Priana Falarima, Said Khaidir, Ari Surida, Nur Muliasari MS, Tara Charissa Oktavia S

“…Furthermore, unsustainable exploitation of sea turtles for cultural and economic purposes also threatens biodiversity. …”
Get full text

Distinct Molecular Effects of Angiotensin II and Angiotensin III in Rat Astrocytes by Michelle A. Clark, Chinh Nguyen, Hieu Tran

“…Previously, we showed that Ang II and Ang III induced mitogen-activated protein (MAP) kinases ERK1/2 and stress-activated protein kinase/Jun-terminal kinases (SAPK/JNK) phosphorylation in cultured rat astrocytes. Most importantly, both peptides were equipotent in causing phosphorylation of these MAP kinases. …”
Get full text

The E3 ubiquitin ligase MARCH1 mediates downregulation of plasma membrane GABAB receptors under ischemic conditions by inhibiting fast receptor recycling by Musadiq A. Bhat, Mohammad Hleihil, Irene Mondéjar, Thomas Grampp, Dietmar Benke

“…We developed an interfering peptide that inhibits the MARCH1/GABAB receptor interaction. Treatment of cultured neurons subjected to ischemic stress with this peptide restored receptor expression and as a consequence stopped progressive neuronal death. …”
Get full text

Exploring drivers and prevention strategies for sexual violence among adolescent girls and young women in Kicukiro, Rwanda by Wongani Patricia Kawonga, Sam M. Livingstone, Augustine Ndaimani, Jean Pierre Sibomana, Tsion Yohannes Waka, Maxwell Mhlanga, Andrew Mclellan

“…Key drivers of sexual violence included substance use, transactional sexual relationships, inadequate family protection, entrenched gender stereotypes, and limited legal literacy.ConclusionFindings underscore the need for multifaceted interventions that address systemic and cultural barriers, strengthen legal frameworks, and expand community-based programs. …”
Get full text

Shifting from Burden Sharing to Task Sharing: Advancing Community-Initiated Care in MHPSS for Refugee Resettlement by Hyojin Im

“…Thematic analysis revealed that peer support models play a critical role as bridges between cultures, service sectors, and formal and informal networks. …”
Get full text

An Emerging Pulmonary Haemorrhagic Syndrome in Dogs: Similar to the Human Leptospiral Pulmonary Haemorrhagic Syndrome? by R. Klopfleisch, B. Kohn, S. Plog, C. Weingart, K. Nöckler, A. Mayer-Scholl, A. D. Gruber

“…Leptospira could not be cultured post mortem from the lungs or kidneys. However, Leptospira-specific PCR was positive in lung, liver or kidneys of three dogs. …”
Get full text

Integration of Rabbit Adipose Derived Mesenchymal Stem Cells to Hydroxyapatite Burr Hole Button Device for Bone Interface Regeneration by Viswanathan Gayathri, Varma Harikrishnan, Parayanthala Valappil Mohanan

“…The results of the MTT (3-(4,5-dimethylthiazol)-2,5-diphenyl tetrazolium bromide) assay indicated that powdered device material was noncytotoxic up to 0.5 g/mL on cultured cells. It was also observed that oxidative stress related reactive oxygen species production and apoptosis on cell seeded device were similar to those of control (cells alone) except in 3-day period which showed increased reactive oxygen species generation. …”
Get full text

AI for chemistry teaching: responsible AI and ethical considerations by Blonder Ron, Feldman-Maggor Yael

“…The UNESCO framework on GenAI in education provides a comprehensive guide to controversies around generative AI and ethical educational considerations, emphasizing human agency, inclusion, equity, and cultural diversity. Ethical issues include digital poverty, lack of national regulatory adaptation, use of content without consent, unexplainable models used to generate outputs, AI-generated content polluting the internet, lack of understanding of the real world, reducing diversity of opinions, and further marginalizing already marginalized voices and generating deep fakes. …”
Get full text

Fas/FasL Pathway Participates in Regulation of Antiviral and Inflammatory Response during Mousepox Infection of Lungs by Karolina Bień, Justyna Sokołowska, Piotr Bąska, Zuzanna Nowak, Wanda Stankiewicz, Malgorzata Krzyzowska

“…Experiments in vitro demonstrated that ECTV-infected cultures of epithelial cells, but not macrophages, upregulate Fas and FasL and are susceptible to Fas-induced apoptosis. …”
Get full text

Artemisinin Stimulates Neuronal Cell Viability and Possess a Neuroprotective Effect In Vitro by Sergey A. Pukhov, Alexey V. Semakov, Nadezhda E. Pukaeva, Olga A. Kukharskaya, Tatyana V. Ivanova, Viktoriya S. Kryshkova, Sergey O. Bachurin, Michail S. Kukharsky

“…In this study, we evaluated the effects of artemisinin on the viability of neuronal-like cells, including primary hippocampal neuronal cultures. Artemisinin exhibited a stimulating effect on SH-SY5Y and HEK-293 cells and enhanced the survival of primary neurons at low concentrations (1 µM). …”
Get full text

Systematic Review into Diagnostics for Post-Kala-Azar Dermal Leishmaniasis (PKDL) by Emily R. Adams, Inge Versteeg, Mariska M. G. Leeflang

“…Twenty-seven studies evaluated serological tests (rK39 dipstick, ELISA, DAT, and leishmanin tests), six studies molecular tests, eight microscopy, and two cultures. Only a few of these studies reported a valid estimate of diagnostic accuracy, as most were case-control designs or used a reference standard with low sensitivity. …”
Get full text

Residual Nitrite, Nitrate, and Volatile N-Nitrosamines in Organic and Conventional Ham and Salami Products by Kathrine H. Bak, Susanne Bauer, Christoph Eisenreich, Peter Paulsen

“…The microbial load in salami products was dominated by bacteria from starter cultures. In ham, a slight increase in total aerobic count and lactic acid bacteria during storage was noted. …”
Get full text

Data Mining Models in Prediction of Vancomycin-Intermediate <i>Staphylococcus aureus</i> in Methicillin-Resistant <i>S. aureus</i> (MRSA) Bacteremia Patients in a Clinical Care Set... by Wei-Chuan Chen, Jiun-Ling Wang, Chi-Chuan Chang, Yusen Eason Lin

“…The resulting models demonstrated high predictive accuracy, with 82.0–86.6% accuracy for 7-day VISA persistence in blood cultures and 53.4–69.2% accuracy for 30-day mortality. …”
Get full text

Study on fungal contaminants in aborted calves of cattle herds in Iran by Samaneh Eidi, Hesam A. Seifi, Soheil Sadr, Hamideh Zeinali

“…The fungi present in the cultures were analysed microscopically and morphologically. …”
Get full text

Candida tropicalis spondylitis in a non-tropical immunocompetent patient: a case report and review of the literature by Hong Yang, Xin Wang, Weijian Zhu, Bei Zhou

“…Postoperatively, disc tissue cultures and next-generation sequencing (NGS) identified Candida tropicalis. …”
Get full text

Explaining the Integrated Approach to Border Management and Control: A Case Study of Iranian Land Borders by reyhane salehabadi, syrus ahmadi, afshin motaghi

“…The findings of the study show that we have five main components of border management in economic, cultural-social, civil, security-military and integrated management, and each of the seven components. …”
Get full text

Comparing Types of Statistical Data Between Turkey (the Case Study of Istanbul) and Selected Countries for Creating Fire Strategies by Erhan Bakırcı, Buket Karatop, Sümeyye Bayındır

“…In addition to material and moral losses and socio-cultural traumas caused by disasters, especially fire disasters, the effects on the eco-system are felt more and more every day. …”
Get full text

Study of the Potential Endocrine-Disrupting Effects of Phenylurea Compounds on Neurohypophysis Cells In Vitro by Krisztián Sepp, Zsolt Molnár, Anna M. László, Tünde Alapi, László Tóth, Andrea Serester, Zsuzsanna Valkusz, Márta Gálfi, Marianna Radács

“…We aimed to examine the potential endocrine-disrupting effects of phenylurea herbicides (phenuron, monuron, and diuron) on the oxytocin (OT) and arginine-vasopressin (AVP) release of neurohypophysis cell cultures (NH). In our experiments, monoamine-activated receptor functions of neurohypophyseal cells were used as a model. …”
Get full text