Effects of Stromal Cell-Derived Factor-1α Secreted in Degenerative Intervertebral Disc on Activation and Recruitment of Nucleus Pulposus-Derived Stem Cells by Jinwei Ying, Zhihua Han, Shishen Pei, Linghao Su, Dike Ruan

“…We found SDF-1α was highly expressed and secreted by the native disc cells when cultured in the proinflammatory mediators in vitro mimicking the degenerative settings. …”
Get full text

Against all odds: women's motivation to become STEM entrepreneurs in Sri Lanka by Arosha Adikaram, Ruwaiha Razik

“…Purpose – This paper aims to explore the motivations behind women in a developing South Asian country – Sri Lanka – to embark on entrepreneurship in science, technology, engineering and mathematics (STEM) fields, which is a doubly masculine hegemony operating within a culturally nuanced gendered context. Design/methodology/approach – The study employs a qualitative research approach, conducting in-depth semi-structured interviews with 15 STEM women entrepreneurs, following the theoretical lenses of push and pull motivation theory and gender role theory. …”
Get full text

Cold Plasma Activity Against Biofilm Formation of Prosthetic Joint Infection Pathogens by Christopher Spiegel, Débora C. Coraça-Huber, Michael Nogler, Rohit Arora, David Putzer

“…Methods: Biofilm was formed with <i>Staphylococcus aureus</i> ATCC 29213 and <i>Staphylococcus epidermidis</i> ATCC 12228 cultures on TMZF discs. Plasma treatments using air plasma and argon plasma were conducted on discs containing the established biofilm while the temperature was measured. …”
Get full text

Selected Parameters of Nutritional and Pro-Health Value in the Common Carp (Cyprinus carpio L.) Muscle Tissue by J. Kłobukowski, K. Skibniewska, K. Janowicz, F. Kłobukowski, E. Siemianowska, E. Terech-Majewska, J. Szarek

“…The muscle tissue of fish cultured in farms with a semiextensive technological level was characterised by the highest content of unsaturated fatty acids. …”
Get full text

Factors contributing to helminth prevalence after repeated mass administration of medicines in Anambra State, Nigeria by Ogechukwu B. Aribodor, Christopher Okaka, Sammy Sam-Wobo, Annick Bikoumou, Emmanuel Obikwelu

“…The persistence of open defecation highlights critical gaps in WASH that undermine sustainable Neglected Tropical Diseases (NTD) control. Addressing cultural and economic challenges, alongside improving WASH infrastructure, is essential to sustain MAM’s impact.…”
Get full text

Pronerve Growth Factor Induces Angiogenesis via Activation of TrkA: Possible Role in Proliferative Diabetic Retinopathy by Sally L. Elshaer, Mohammed A. Abdelsaid, Ahmad Al-Azayzih, Parag Kumar, Suraporn Matragoon, Julian J. Nussbaum, Azza B. El-Remessy

“…The angiogenic response of aqueous humor samples from PDR patients was examined in human retinal endothelial cells in the presence or absence of anti-proNGF antibody. Additional cultures were treated with mutant-proNGF in the presence of specific pharmacological inhibitors of TrkA and p75NTR receptors. …”
Get full text

Differential Proliferative Characteristics of Alveolar Fibroblasts in Interstitial Lung Diseases: Regulative Role of IL-1 and PGE2 by Elizabeth Fireman, Shlomo Ben Efraim, Joel Greif, Hava Peretz, Shmuel Kivity, Marcel Topilsky, Yosef Rodrig, A. Yellin, Ron N. Apte

“…Steady levels of IL-1α and βmRNA were expressed in unstimulated and stimulated cultures. Fb from SA and HP patients could be stimulated by LPS to secrete significantly higher levels of PGE2 than those detected in supernatants from LPS stimulated Fb of DIF patients. …”
Get full text

Occurrence of macrolides resistance in Legionella pneumophila ST188: Results of the Belgian epidemiology and resistome investigation of clinical isolates by Charlotte Michel, Fedoua Echahidi, Geraldine De Muylder, Max Sewell, Ian Boostrom, Olivier Denis, Owen B. Spiller, Denis Pierard

“…Routine typing by cgMLST allows good discrimination and the first clinical isolate reported as resistant for macrolides was cultured, underscoring the need to define resistance breakpoints and incorporate antimicrobial susceptibility testing as routine clinical investigation practice.…”
Get full text

Strains of a virtuoso: pacemaker infection and ventricular tachycardia in a violinist by Yuanguo Chen, Haibo Zhang, Qi Qiao, Lian Ma

“…Despite initial antibiotic treatment, the infection persisted with slightly elevated C-reactive protein (CRP) and negative cultures. The VT originated from the right ventricular outflow tract (RVOT), as confirmed by echocardiography and ECG findings. …”
Get full text

Protocolo de investigação e manejo do AVC isquêmico neonatal by Nicolas Ramos, Gustavo Barbosa David, Simone Cristina Stadnick, Stephanie Ribeiro Raitez

“…Laboratory tests did not clarify the situation, therefore blood cultures and cerebrospinal fluid samples were requested. …”
Get full text

The use of Spirulina platensis as tilapiaOreochromis niloticusdiet supplementation by Nur Bambang Priyo Utomo, Firsty Rahmatia, Mia Setiawati

“…Tilapia rearedin aquarium sized 50×40×35 cm3 filledwith 30 cm waterand provided altrecirculation system. Fish were cultured for 40 days and fed at satiation with three times feeding frequency. …”
Get full text

Type and physical intensity of occupations at pulmonary TB diagnosis by M. Saroufim, C. Geric, A. Majidulla, A. Abjani, G. Tavaziva, S. Saeed, A.J. Khan, F. Ahmad Khan

“…DESIGN/METHODS: We did a secondary analysis of data from a study evaluating the diagnostic accuracy of artificial intelligence-based chest X-ray (CXR) analysis software, where individuals had been evaluated for active PTB using sputum cultures and had provided information on occupation. …”
Get full text

Assessing in-vitro models for microglial development and fetal programming: a critical review by Steven Schepanski, Steven Schepanski, Gonza B. Ngoumou, Gonza B. Ngoumou, Claudia Buss, Claudia Buss, Claudia Buss, Claudia Buss, Georg Seifert, Georg Seifert

“…The models examined include primary microglia cultures, microglia cell lines, iPSC-derived microglia, PBMC-induced microglia-like cells, 3D brain organoids derived from iPSCs, and Hofbauer cells. …”
Get full text

An investigation of factors associated with antenatal care attendance in Gauteng in 2015 by E M Webb, B Girdler-Brown, J Mostert, S Ngcobo

“…There are several studies on the social and cultural reasons for late booking. However, understanding the factors in a woman’s choice to initiate antenatal care is important in informing healthcare strategies and policies. …”
Get full text

Machine Learning-Based Classification of Turkish Music for Mood-Driven Selection by Nazime Tokgöz, Ali Değirmenci, Ömer Karal

“…The act of selecting music based on emotional states is important on both a universal and cultural level. This study seeks to employ machine learning-based methods to classify four different music genres using a minimal set of features. …”
Get full text

The most comprehensive history of fire activity in the Pur-Taz interfluve over the last 11,000 years (Western Siberia, Russia) by Nikita V. Shefer, Sergey V. Loiko, Ivan V. Kriсkov, Artem G. Lim

“…For the third period, a temporal relationship between fire frequency and archaeological cultures is noted. It was also established that in the second half of the Holocene in the southern tundra peat accumulation was not interrupted in fens permafrost polygonal peat plateaus. …”
Get full text

Multisite Infection with Mycobacterium abscessus after Replacement of Breast Implants and Gluteal Lipofilling by Eva Rüegg, Alexandre Cheretakis, Ali Modarressi, Stephan Harbarth, Brigitte Pittet-Cuénod

“…Bacterial analysis of periprosthetic and gluteal liquids included Gram-stain plus acid-fast stain, and aerobic, anaerobic and mycobacterial cultures.  Results. In periprosthetic fluid, Mycobacterium abscessus, Propionibacterium, and Staphylococcus epidermidis were identified. …”
Get full text

Isolation and Characterization of Multipotent Turkey Tendon-Derived Stem Cells by Qian Liu, Yaxi Zhu, Peter C. Amadio, Steven L. Moran, Anne Gingery, Chunfeng Zhao

“…Approximately 4% of the nucleated cells demonstrated clonogenicity, high proliferation rate, and trilineage differentiation potential after induction culturing. These cells expressed surface antigens CD90, CD105, and CD44, but did not express CD45. …”
Get full text

Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy by Xuwei Hou, Zhaohui Li, Yusuke Higashi, Patrice Delafontaine, Sergiy Sukhanov

“…We found that IGF-1 decreased cell senescence, prevented DNA telomere shortening, increased mitochondrial membrane potential, activated cytochrome C oxidase, and reduced mitochondrial DNA damage in long-term cultured (aged) aortic SMC, suggesting an antiaging effect. …”
Get full text

CCL5 Induces a Sarcopenic-like Phenotype via the CCR5 Receptor by Francisco Aguirre, Franco Tacchi, Mayalen Valero-Breton, Josué Orozco-Aguilar, Sabrina Conejeros-Lillo, Josefa Bonicioli, Renata Iturriaga-Jofré, Daniel Cabrera, Jorge A. Soto, Mauricio Castro-Sepúlveda, Marianny Portal-Rodríguez, Álvaro A. Elorza, Andrea Matamoros, Felipe Simon, Claudio Cabello-Verrugio

“…Therefore, we evaluated whether CCL5 and CCR5 induce a sarcopenic-like effect on skeletal muscle tissue and cultured muscle cells. Electroporation in the tibialis anterior (TA) muscle of mice was used to overexpress CCL5. …”
Get full text