Lacticaseibacillus paracasei K56 inhibits lipid accumulation in adipocytes by promoting lipolysis by Silu Wang, Jinxing Li, Wei-Hsien Liu, Niya Li, Huijing Liang, Weilian Hung, Qiuyue Jiang, Ruyue Cheng, Xi Shen, Fang He

“…This study aimed to explore the functions of Lacticaseibacillus paracasei K56 (K56), in regulating the lipid metabolism of adipocytes and its immune regulation mechanisms. We co-cultured RAW264.7 macrophages with K56, and the K56-stimulated RAW264.7-conditioned medium (K56-CM) was collected and treated with 3T3-L1 pre-adipocytes. …”
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Beneficial arthropods threatened by synthetic agricultural pesticides around the southeast slopes of Mount Cameroon by Daniel Brice Nkontcheu Kenko, Agathe Lambou Fotio, Kenfack Donhachi Aimerance, Derick Atemlefac Acha, Miranda Egbe Awo, Eric Bertrand Fokam

“…Pesticides active ingredients such as abamectin, fipronil, imidacloprid, thiamethoxam, emamectin-benzoate, cypermethrin and lambda-cyhalothrin that were predicted to pose “Risk” both to bees and others NTAs require serious mitigation strategies (biological control, improve cultural practices, target application, farmer's education).…”
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Sustained Interleukin-1β Exposure Modulates Multiple Steps in Glucocorticoid Receptor Signaling, Promoting Split-Resistance to the Transactivation of Prominent Anti-Inflammatory Ge... by Pedro Escoll, Ismael Ranz, Norman Muñoz-Antón, Ana van-den-Rym, Melchor Alvarez-Mon, Carlos Martínez-Alonso, Eva Sanz, Antonio de-la-Hera

“…As sustained IL-1β exposure is key in the pathogenesis of several major diseases with prevalent GCR, we examined GR signaling and the mRNA expression of six GR-driven genes in cells cultured in IL-1β and afterwards challenged with GC. …”
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Presenting a Model for Training Reflective Managers for Farhangian University by Mohammad Ahmadi beni, Masoumeh Oladian, Mahmoud Safari

“…Furthermore, the proposed model encompasses strategies for the advancement of reflective managers influenced by causal factors (such as educational influences, development opportunities, critical reflective thinking, and the personality traits and skills of managers), contextual factors (which include access to university infrastructure, the cultural milieu of the university, and support from higher-level organizations), as well as various intervening variables. …”
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Trust as a key element in family mediation during divorce: strategies, practices (supervision experience with the use of neural networks) by V. V. Krivopuskov, I. V. Mkrtumova, O. E. Gracheva

“…The research presents arguments proving that the first outreach meeting is a successful strategy of trust building and the first step to mediation and to preservation of family, family identity, spiritual values for their further transmission to the next generation in the continuous chain of socio-cultural identity…”
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Exploring oral candidiasis among cancer patients undergoing chemotherapy in eastern Iran by Abdol Sattar Pagheh, Fatemeh Kardan, Aynaz Ghojoghi, Ahmad Reza Sebzari, Maryam Erfaninejad, Parvin Askari, Seyed Reza Aghili, Eisa Nazar, Masood Ziaee

“…Materials and Methods: The samples were obtained from the oral cavity of 140 patients and the initial identification of Candida species was carried out through fungal cultures. Subsequently, Candida isolates were molecularly identified using the PCR-RFLP method with the restriction enzyme Msp1. …”
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Determinants of Malaria Prevention and Treatment Seeking Behaviours of Pregnant Undergraduates Resident in University Hostels, South-East Nigeria by Anthonia Ukamaka Chinweuba, Noreen Ebelechukwu Agbapuonwu, JaneLovena Enuma Onyiapat, Chidimma Egbichi Israel, Clementine Ifeyinwa Ilo, Joyce Chinenye Arinze

“…Knowledge, academic schedule, cultural influence on perception and decision-making, and accessibility of health facility were key determinants of the women’s preventive and treatment seeking behaviours. …”
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Enhancing Thermal Comfort in Historic Buildings by Wind-Driven Ventilation Systems—A Case Study of the Praterateliers in Vienna by Aida Shayegani, Viera Joklova, Katarina Kristianova, Juraj Illes

“…By addressing the unique challenges posed by cultural heritage buildings, such as the Praterateliers’ Pavilions, this research highlights the role of sustainable ventilation strategies in mitigating urban overheating, which is exacerbated by climate change. …”
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Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration by Lewis E. Fry, Lauren Major, Ahmed Salman, Lucy A. McDermott, Jun Yang, Andrew J. King, Michelle E. McClements, Robert E. MacLaren

“…We compare the Cas13 effectors PspCas13b and Cas13bt3 for the repair of the gene USH2A, a common cause of inherited retinal disease and Usher syndrome. In cultured cells, we demonstrate up to 80% efficiency for the repair of the common c.11864 G > A and its murine equivalent c.11840 G > A, across different gRNAs and promoters. …”
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Improved production strain maintenance technique for Burkholderia mallei 5584 (Master seed) used for glander diagnostic agent production by E. A. Artemeva, L. A. Melnikova, L. I. Zaynullin, N. K. Bukova

“…This technique allows for the strain sub-culturing on sensitive models once every 5 years, which is more expedient and safe from an economic and biological point of view. …”
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Interaction of drivers and barriers of sustainable property management practice in shopping malls in Lagos, Nigeria by Lumbani B. Nyirenda, Caleb A. Ayedun, Innocent Musonda, Chukwuemeka O. Iroham, David O. Olukanni, Hilary I. Okagbue, Olugbemisola W. Samuel, Sunday E. Nto

“…Financial and economic barrier (4.2/5) were top while cultural factors (3.97/5) were the least. The interactions of the latent barrier factors were exposed by the CFA and mediated regression models. …”
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Validation of the Arabic Version of Medication Regimen Complexity Index Among Older Patients - Validation of the “MRCI-Arabic” by Nilay Aksoy, Nur Ozturk, Betul Okuyan, Mesut Sancar

“…After the translation and cultural adaptation process finished, medication regimens of 30 patients were evaluated for test-retest reliability three weeks apart by the rater who was a native Arabic speaker. …”
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Effect of Compression Loading on Human Nucleus Pulposus-Derived Mesenchymal Stem Cells by Hang Liang, Sheng Chen, Donghua Huang, Xiangyu Deng, Kaige Ma, Zengwu Shao

“…Human NP-MSCs were isolated from patients undergoing lumbar discectomy for IVD degeneration and were identified by immunophenotypes and multilineage differentiation. Then, cells were cultured in the compression apparatus at 1.0 MPa for different times (0 h, 24 h, 36 h, and 48 h). …”
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Establishment of a Virus-Induced Gene Silencing System in <i>Abelmoschus manihot</i> L. by Ting Zhang, Jiaqi Hou, Hongtao Chu, Pengyu Guo, Qianzi Sang, Zhongxu Liu, Li Cao

“…The results demonstrated that administering two injections—the first on the day of complete cotyledon expansion and the second 14 days later—using pTRV1 and pTRV2–<i>AmPDS</i> cultures resuspended to an OD₆₀₀ of 1.0 and via the backside of the blade—led to significant photobleaching in the cotyledons 2 days after the second injection. …”
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Understanding the drivers of a pro-environmental attitude in higher education institutions: the interplay between knowledge, consciousness, and social influence by Aqsa Sehar, Orangzab, Minhas Akbar, Minhas Akbar, Petra Poulova, Asokan Vasudevan, Tianjiao Huang

“…Overall, this study contributes original insights into the factors influencing pro-environmental attitudes among faculty in a specific cultural and educational context. Its findings can inform targeted strategies to enhance environmental education and engagement in higher education, making it a valuable addition to the literature on education for sustainable development. …”
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The Mediating Role of Trust in Shaping Customer Loyalty of Bank: Insighths from a developing country perspective by Husne Jahan, Chowdhury, G. M. Azmal Ali, Quaosar, Nazifa Anbar, Saba, Md Abidur, Rahman

“…By focusing on a specific geographic region and industry, this study provides insights that are tailored to the nuances of the cultural, economic, and regulatory environment, thereby filling a gap in the literature on trust and loyalty in emerging market economies. …”
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Prenatal Identification and Molecular Characterization of Two Simultaneous De Novo Interstitial Duplications of Chromosomal Regions 7p22.1p21.1 and 15q24.1 by Sabrina C. Burn, Kali Swift, Maria Palmquist

“…Cytogenetic analysis of cultured amniocytes by conventional chromosome analysis, comparative genomic hybridization, and fluorescence in situ hybridization revealed two interstitial duplications of the chromosomal regions 7p22.1p21.1 and 15q24.1, leading to partial trisomy of 7p and 15q and karyotype 46,XY,dup(7)(p22.1-p21.1),dup (15)(q24.1). …”
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Protocol for the development and multisite validation of the Quality of Dying and Death-Revised Global Version scale by Camilla Zimmermann, Ekaterina An, Sarah Hales, Gary Rodin, Eve Namisango, Kenneth Mah, Lameck Thambo, Christian Ntizimira, Alyssa Tilly, Warren Lewin, Mano Chandrakumar, Arnell Baguio, Nazira Jaffer, Maria Chikasema, Kayla Wolofsky, Mary Goombs

“…The aim of this multisite cross-sectional study is to develop and validate the QODD-Revised Global Version (QODD-RGV), to enhance ease of completion and relevance in higher-resource and lower-resource settings.Methods and analysis This study will be a two-arm, multisite evaluation of the cultural relevance, reliability and validity of the QODD-RGV across four participating North American hospices and a palliative care site in Malawi, Africa. …”
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Adiponectin regulates proliferation and differentiation of chicken skeletal muscle satellite cells via ERK1/2 and p38 signaling pathways by Liping Guo, Kaiming Jin, Qi Sun, Chenchao Zhang, Xiongyong Chen, Zhaoyu Geng

“…In this study, we investigated the effects of adiponectin on the proliferation and differentiation of in vitro cultured chicken SMSCs. Our results demonstrated that adiponectin promoted SMSCs proliferation while inhibiting myogenic differentiation and inducing adipogenic differentiation. …”
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Acceptability of Children Road Safety Education in Pakistan: A Mixed-Method Approach to Exploring Parents’ and Teachers’ Perspectives by Imran Nawaz, Ariane Cuenen, Geert Wets, Davy Janssens

“…Key barriers to RSE implementation include cultural norms, inadequate infrastructure, and limited teacher training. …”
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