Fluticasone Propionate in Inflammatory Bowel Disease by Marta Carpani de Kaski, Humphery JF Hodgson

“…In particular, fluitcasone propionate is a fluorinated glucocorticoid, in which systemic side effects are absent or minimal due to its relatively low absorption and rapid first pass metabolism In an open trial in 12 patients with mild and moderately active Crohn's disease, administration of 20 mg fluitcasone propionate orally was associated with a significant fall in the Crohn's disease activity index and improvement in other parameters of inflammation, without change in either plasma cortisol levels or responsiveness to adrenocorticotropic hormone, suggesting that this drug is a promising therapy for Crohn's disease meriting evaluation against conventional corticosteroids.…”
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Prospective Evaluation of Neutrophil Autoantibodies in 500 Consecutive Patients with Inflammatory Bowel Disease by Hugh Freeman, Brenda Roeck, Dana Devine, Cedric Carter

“…Five hundred patients were evaluated, including 247 patients with ulcerative colitis and 253 with Crohn's disease involving the small and/or large intestine. …”
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Long-Term Clinical Behavior of Jejunoileal Involvement in Crohn’s Disease by Hugh J Freeman

“…Diffuse and extensive jejunoileal Crohn's disease is an uncommon entity. In 39 patients, including 21 males and 18 females, followed for a mean duration of over 16 years between 1979 and 2004, the extent of disease was defined and disease behaviour characterized. …”
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Combination Ciprofloxacin and Metronidazole for Active Crohn’s Disease by Susan L Greenbloom, A Hillary Steinhart, Gordon R Greenberg

“…Recent experimental evidence underscores the contribution of intestinal bacteria to the inflammatory process of Crohn's disease. This open study examined the efficacy and safety of combination ciprofloxacin and metronidazole for patients with active Crohn's disease of the ileum and/or colon. …”
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Cancer Risk in Inflammatory Bowel Disease by Anders M Ekbom

“…There is an increased risk of cancer in both ulcerative colitis and Crohn's disease. In 3121 patients with ulcerative colitis, 225 cases of cancer were diagnosed compared with 142.1 expected (standardized incidence ratio [SIR] 1.6, 95% CI 1.4 to 1.8), and in 1655 patients with Crohn's disease, 58 cases of cancer were detected compared with 47.1 expected (SIR 1.2, 95% CI 0.9 to 1.6). …”
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Colonic Tuberculosis Clinically Misdiagnosed as Anorexia Nervosa and Radiologically and Histopathologically as Crohn’s Disease by Tariq A Madani

“…The radiologist believed that these findings were due to Crohn's disease. Colonoscopic biopsies from the involved area revealed histopathological changes typical of Crohn's disease and not tuberculosis. …”
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Extraintestinal manifestations of inflammatory bowel diseases: arthropathy and arthritis by Gulustan Hamid Sadygova

“…Ulcerative colitis and Crohn's disease represent the group of the diseases with unknown etiology encompassed by the term «inflammatory bowel diseases». …”
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Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer by Yao Mao, Jian'an Ren, Jieshou Li

“…We aimed to clarify the role of different arachidonic pathways and the interrelationships between them in Crohn's disease. Methods. Seventeen specimens of Crohn's disease dated between 2003/1/1 and 2005/1/1 were collected and underwent immunohistochemical analyses with cylcooxygenase 1, cyclooxygenase 2, 5-lipoxygenase, and 15-lipoxygenase-1 antibodies. …”
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Keeping an Eye on Crohn’s Disease: Orbital Myositis as the Presenting Symptom by Carol A Durno, Robert Ehrlich, Robert Taylor, J Raymond Buncic, Peter Hughes, Anne Marie Griffiths

“…It is important to recognize that orbital myositis may be an extraintestinal manifestation of Crohn's disease so that the diagnosis can be made and appropriate therapy commenced.…”
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Osteomyelitis and Osteonecrosis in Inflammatory Bowel Disease by Hugh J Freeman

“…Osteomyelitis usually occurs in the pelvic bones, especially in complicated Crohn's disease, presumably by direct extension from a pelvic inflammatory mass, abscess or fistulous tract. …”
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Budesonide in the Management of Patients with Crohn’s Disease by ABR Thomson, Daniel Sadowski, Robert Jenkins, Gary Wild

“…Thus, budesonide is the safer, more effective steroid of choice to treat patients with Crohn's disease.…”
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Population features of prevalence and clinical-diagnostic role of NOD2 gene polymorphisms associated with Crohn’s disease by D. A. Kuznetsova, M. V. Merzlyakov, G. V. Vavin, A. S. Razumov, V. L. Emanue

“…To discuss features of prevalence and the clinicodiagnostic role of R702W, G908R and 3020insC NOD2 gene polymorphisms associated to Crohn's disease (CD) in various populations and regions of the world. …”
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Immune-Mediated Cytotoxicity in Inflammatory Bowel Disease by Stephan R Targan, Richard L Deem, Fergus Shanahan

“…This same change is seen near aphthous ulcers in patients with Crohn's disease. Soluble cytokines produced by T cells might be responsible for the mucosa! …”
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Inflammatory Bowel Disease Incidence and Prevalence in Southern Alberta by Faith G Davis, Michael G Grace, Noel Hershfield

“…A bimodal age distribution and female predominance in the younger age groups was apparent for Crohn's disease.…”
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Potential Human Models of Infammatory Bowel Disease by Stephen B Hanauer

“…Similar to animal models of inflammatory bowel disease (IBD), there is no single human model representative of ulcerative colitis or Crohn's disease. An optimal human model awaits etiopathogenetic definitions and further reclassification or depiction of clinicopathological scenarios. …”
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Validation of a Model Estimating the Budget Impact of Video Capsule Endoscopy for Surveillance of Crohn’s Disease in an Italian Center by Rhodri Saunders, Carlo Calabrese, Dania Gelli, Jason Davis, Rafael Torrejon Torres

“…**Background:** Crohn's disease is a chronic ailment affecting the gastrointestinal tract. …”
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Regulated Spatial Distribution of Cyclooxygenases and Lipoxygenases in Crohn's Ulcer

“…Seventeen specimens of Crohn's disease dated between 2003/1/1 and 2005/1/1 were collected and underwent immunohistochemical analyses with cylcooxygenase 1, cyclooxygenase 2, 5-lipoxygenase, and 15-lipoxygenase-1 antibodies. …”
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Genetic Counselling and Family in IBD: 30 years' Experience at the Cleveland Clinic by WM Michener, M Caulfield, RG Farmer, R Wyllie, K Cotman, J Hertzer

“…ulcerative colitis and 851 with Crohn's disease) from 1955 through 1984. Of the 437 patients with mucosal ulcerative colitis, the index patient had one or more family members develop IBD. …”
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Practice affairs committee by Dan Sadowski

“…A major activity in 2003 was participation in the drafting of several new clinical practice guidelines: Infliximab and the management of Crohn's disease;Screening for colorectal cancer; andManagement of gastroesophageal reflux disease.…”
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Oral Contraceptives, Sex, Pregnancy and Breast Feeding in Inflammatory Bowel Disease by RN Allan

“…The information should be reinforced by simple, concise, clear information booklets, such as those produced by the National, Association for Colitis and Crohn's Disease.…”
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