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  1. 1761

    Sarcopenia is not associated with hypertension, but sarcopenic obesity increases risk of hypertension: a 7-year cohort study by Runfen Du, Junchao Yuan, Yunda Huang, Guihua Jiang, Zhiping Duan, Hong Yang, Wei Huang

    Published 2025-01-01
    “…BackgroundSarcopenia, sarcopenic obesity, and hypertension are all widespread public health problems in middle-aged and older populations, and their association is controversial. The purpose of this study is to analyze the relationship between obesity, sarcopenia, and sarcopenic obesity with hypertension in a middle-aged and older community population in China through a large-scale longitudinal design.MethodsIn this cohort study with 7 years of follow-up, the study population was drawn from participants in the China Health and Retirement Longitudinal Study (CHARLS) in 2011 and followed up in 2013, 2015, and 2018. …”
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  2. 1762

    AGENTS USED FOR ENAMEL REMINERALISATION AND REDUCING DENTIN HYPERSENSITIVITY: A COMPREHENSIVE REVIEW by N.V. Yanko

    Published 2020-04-01
    “…Simultaneously, the data about calcium phosphate and deep penetration fluoridation efficacy over such desensitisers as dentin sealants and nerve sensitivity inhibitors are controversial and indicate that additional studies are required to deepen our knowledge of the insufficiently explored area of reducing dentin hypesensitivity. …”
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  3. 1763

    Separating the Effects of Early-Life and Adult Body Size on Chronic Kidney Disease Risk: A Mendelian Randomization Study by Xunliang Li, Wenman Zhao, Haifeng Pan, Deguang Wang

    Published 2025-01-01
    “…Background : Whether there is a causal relationship between childhood obesity and increased risk of chronic kidney disease (CKD) remains controversial. This study sought to explore how body size in childhood and adulthood independently affects CKD risk in later life using a Mendelian randomization (MR) approach. …”
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  4. 1764

    Refining MR-guided thermal ablation for HCC within the Milan criteria: a decade of clinical outcomes and predictive modeling at a single institution by Fu-Qun Wei, Pei-Shu Huang, Bing Zhang, Rui Guo, Yan Yuan, Jin Chen, Zheng-Yu Lin

    Published 2025-01-01
    “…Abstract Background The appropriateness of ablation for liver cancer patients meeting the Milan criteria remains controversial. Purpose This study aims to evaluate the long-term outcomes of MR-guided thermal ablation for HCC patients meeting the Milan criteria and develop a nomogram for predicting survival rates. …”
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  5. 1765

    Review on the Injury and Repair Mechanism of Skeletal Muscle Contusions by LIN Jianping, WANG Hao, GUO Mingling, WANG Shizhong, CHEN Shaoqing

    Published 2022-02-01
    “…However, current research on the role of Wnt signal pathway in the regeneration of mature muscle is controversial, and more studies are needed in the future. …”
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  6. 1766

    Ciencismo versus Dialéctica by Paul Lorenzen, Leizi Nuri Capilla Rodríguez, Ánderson Bolívar Miranda

    Published 2017-12-01
    “…Desde entonces la controversia ha sido continuada —claramente, de forma más polémica— por Habermas y Albert. El problema aquí controversial tiene una larga historia previa. No obstante, no necesito regresar a la Antigüedad. …”
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  7. 1767

    Antitumor effect of Bothrops jararaca venom by Reinaldo J. da Silva, Márcia G. da Silva, Lízia C. Vilela, Denise Fecchio

    Published 2002-01-01
    “…Many experimental studies have been carried out using snake venoms for the treatment of animal tumors, with controversial results. While some authors have reported an antitumor effect of treatment with specific snake venom fractions, others have reported no effects after this treatment. …”
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  8. 1768

    Efficacy and safety of anticoagulants on venous thromboembolism: a systematic review and network meta-analysis of randomized controlled trials by Weijie Fu, Maolin Zhao, Sheng Ding, Mei Xin, Ke Yang, Li Jiang, Fan Wu, Xiaochen Wu, Jian Wang, Jie Chen, Feng Gao, Siyi He

    Published 2025-01-01
    “…BackgroundAnticoagulants are the primary means for the treatment and prevention of venous thromboembolism (VTE), but their clinical standardized application still remains controversial. The present study intends to comprehensively compare the efficacy and safety of various anticoagulants in VTE.MethodsMedline, Embase, and Cochrane Library from their inception up to August 2023 were searched to compare the efficacy and safety of various anticoagulants in VTE. …”
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  9. 1769

    “The Founder and Father of his Empire”: Voltaire on the Peace of Nystad and the Imperial Status of Russia by S. A. Mezin

    Published 2022-09-01
    “…The focus of the paper is on the up to the present-day controversial issue, whether Peter I was involved in Gorth–Alberoni conspiracy, aimed at the complete political change in the appearance of Europe. …”
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  10. 1770

    A colheita da floresta: Uma estratégia de desenvolvimento social e economicamente viável ao desmatamento? by Patricia Andrade de Oliveira

    Published 2010-07-01
    “…The fourth part examines the controversies over the “harvest” concept as a socially and economically equitable alternative to deforestation. …”
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  11. 1771

    Systemic Poverty Modelling: Case of Central Asia by F. I. Arzhaev, V. Y. Andriukhin, D. V. Saprynskaya

    Published 2022-12-01
    “…Poverty is one of the most controversial issues in the academic discourse. The numerous theories and their different interpretations make theoretical approaches to poverty applicable to achieve different goals but not the one of its eradication. …”
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  12. 1772

    Embryo Density and Its Neutrality in Day-3 Embryo Development: A Retrospective Cohort Study by Cheng Shi, Tie Cheng Sun, Shi Hui Meng, Ping Wang, Rong Liang, Sheng Nan Duan, Hong Jing Han, Ya Nan Liu, Huan Shen, Xi Chen

    Published 2022-01-01
    “…Many studies have shown that embryo density has an impact on day-3 embryo-developmental outcomes; however, embryo density remains controversial in clinical practice. We aimed to evaluate the association between embryo density and day-3 embryo-developmental outcomes in real world with the largest sample size. …”
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  13. 1773

    High prevalence of p16 staining in malignant tumors. by Noémi De Wispelaere, Sebastian Dwertmann Rico, Marcus Bauer, Andreas M Luebke, Martina Kluth, Franziska Büscheck, Claudia Hube-Magg, Doris Höflmayer, Natalia Gorbokon, Sören Weidemann, Katharina Möller, Christoph Fraune, Christian Bernreuther, Ronald Simon, Christian Kähler, Anne Menz, Andrea Hinsch, Frank Jacobsen, Patrick Lebok, Till Clauditz, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Eike Burandt, Rainer Krech, David Dum, Till Krech, Andreas Marx, Sarah Minner

    Published 2022-01-01
    “…However, the prevalence of p16 expression in different cancer types is controversial. 15,783 samples from 124 different tumor types and 76 different normal tissue types were analyzed by immunohistochemistry in a tissue microarray format. p16 was detectable in 5,292 (45.0%) of 11,759 interpretable tumors. …”
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  14. 1774

    Genetic variations suggests that Takifugu rubripes, T. chinensis, and T. pseudommus are the same species with a shared gene pool by Ji Young Lee, Kun Hee Kim, Hyuk Je Lee, Sun-Goo Hwang, Tae Sun Kang

    Published 2025-01-01
    “…Specifically, T. rubripes, T. pseudommus, and T. chinensis are remarkably similar in appearance and genetics, and their classification remains controversial. Here, we provide comprehensive genetic and genomic evidence regarding their speciation and classification.MethodsWhole genome sequencing was performed on T. pseudommus, leading to the identification and development of 15 novel tandem simple sequence repeats (SSRs) from its genomic data. …”
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  15. 1775

    Hydrocortisone for Preventing Adverse Drug Reactions to Snake Antivenom: A Meta-Analysis by Jihua Feng, Zimeng Wu, Qiao Yu, Hongyuan Li, Pan Ji, Yanli Yang, Xiaoliang Zeng, Xiaowen Zheng, Chunling Zhao, Jianfeng Zhang

    Published 2022-01-01
    “…Pretreatment with hydrocortisone (prehydrocortisone) has been used to protect against adverse drug reactions (ADRs) following antivenom administration after snakebite. However, controversial results have been reported in studies evaluating its efficacy. …”
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  16. 1776

    Peculiarities of determining the circle of recipients of one-time financial assistance in case of death of a serviceman, person liable for military service or reservist under marti... by О. V. Dzhafarova, S. O. Shatrava, О. V. Pohorilets

    Published 2023-09-01
    “…It has been stressed that the issue of determining the list of persons who should be considered family members entitled to this social payment remains controversial. A scientific analysis of the content of the Law of Ukraine “On Amendments to the Law of Ukraine “On Social and Legal Protection of Servicemen and Members of Their Families” regarding the Appointment and Payment of a One-time Financial Allowance” dated 29 July 2022 No. 2489-IX has been carried out. …”
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  17. 1777

    Cardiovascular and Metabolic Adverse Events of Endocrine Therapies in Women with Breast Cancer: A Disproportionality Analysis of Reports in the FDA Adverse Event Reporting System by Shaimaa Elshafie, Lorenzo Villa‐Zapata, Randall L. Tackett, Iman Y. Zaghloul, Henry N. Young

    Published 2025-01-01
    “…Conclusion Our findings provide valuable evidence on common reactions as well as controversial cardiovascular and metabolic abnormalities associated with the real‐world use of ETs for breast cancer. …”
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  18. 1778

    Use of Simultaneous Bilateral Cataract Surgery (SBCS) to Optimize Parameters Affecting the Subjective Perception of the Procedure by P. Studený, J. Vránová, L. Nováček

    Published 2021-01-01
    “…Simultaneous Bilateral Cataract Surgery (SBCS) is still a relatively controversial procedure. The main objection is the risk of bilateral endophthalmitis or bilateral refractive error. …”
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  19. 1779

    Prevalence of metabolic syndrome with different serum vitamin D levels in middle-aged and older adults by Ya Zhao, Danting Su, Lichun Huang, Mengjie He, Dan Han, Dong Zhao, Yan Zou, Ronghua Zhang

    Published 2025-01-01
    “…Abstract Background The relationship between serum vitamin D levels and metabolic syndrome (MetS) has been controversial. This study focused on the relationship between the prevalence of MetS and serum vitamin D levels in middle-aged and elderly people. …”
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  20. 1780

    The efficacy of mindfulness-based interventions for patients with COPD: a systematic review and meta-analysis protocol by Li Li, Ying Wu, Ying Zhang, Lingyun Tian, Yinglan Li

    Published 2019-05-01
    “…Although some studies on the intervention effect of MBIs in patients with COPD have been conducted, the results are controversial, especially on dyspnoea, level of mindfulness and quality of life. …”
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