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41001
Risk factors associated with in-hospital mortality during yellow fever outbreak in Brazil
Published 2025-01-01“…ObjectiveTo characterize the clinical manifestations of yellow fever disease and identify risk factors for mortality.MethodsA retrospective study was conducted in the referral center for infectious diseases (Hospital Eduardo de Menezes-HEM) in Belo Horizonte, Minas Gerais, Brazil. …”
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41002
Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya
Published 2025-02-01“…A thematic analysis was conducted using five dimensions of acceptability: content, complexity, comfort, delivery, and credibility.ResultsThe mean age was 43.9 years (SD 4.4), and seven (58%) had primary education or less. …”
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41003
Six months of hybrid closed-loop therapy improves diabetes-specific positive well-being, and reduces diabetes distress and fear of hypoglycemia: secondary analysis of a randomized...
Published 2024-12-01“…Linear mixed models were conducted, using restricted maximum likelihood estimation, unadjusted and adjusted (for covariates: age, sex, diabetes duration, glycated hemoglobin, recent severe hypoglycemia, pre-trial insulin delivery modality, enrollment and mid-study scores).Results 120 participants (mean age 44±12 years) were randomized to intervention (n=61) or standard therapy (n=59). …”
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41004
Sex-specific associations between body composition and depression among U.S. adults: a cross-sectional study
Published 2025-01-01“…After accounting for confounding variables, the associations between fat mass index (FMI), appendicular skeletal muscle mass index (ASMI), body fat percentage (BFP), body composition phenotypes, and depression risk were assessed using restricted cubic spline (RCS) curves and multivariable logistic regression models. We further conducted interaction analyses for ASMI and FMI in females. …”
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41005
Social vulnerability and genetic service utilization among unaffected BRIDGE trial patients with inherited cancer susceptibility
Published 2025-01-01“…Abstract Background Research on social determinants of genetic testing uptake is limited, particularly among unaffected patients with inherited cancer susceptibility. Methods We conducted a secondary analysis of the Broadening the Reach, Impact, and Delivery of Genetic Services (BRIDGE) trial at University of Utah Health and NYU Langone Health, involving 2,760 unaffected patients meeting genetic testing criteria for inherited cancer susceptibility and who were initially randomized to either an automated chatbot or an enhanced standard of care (SOC) genetic services delivery model. …”
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41006
Efficacy of PARPi re-maintenance therapy for recurrent ovarian cancer
Published 2025-01-01“…A propensity-score matching (PSM) analysis was conducted between re-maintenance therapy group (Re-PARPi-P) and chemotherapy alone group(Chem-A-P)to adjust for imbalanced risk factors. …”
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41007
Association of genetic variations in the NOS1 gene with insomnia, sleep duration and obstructive sleep apnea-related clinical quantitative traits
Published 2024-12-01“…Regression analysis was conducted to assess the associations between rs7305526 and rs11615756 with insomnia and sleep duration based on the United Kingdom Biobank (UKB) Genome-Wide Association Study (GWAS) dataset. …”
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41008
Ethnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from...
Published 2025-02-01“…Our objectives were to assess whether the risk of respiratory and neurologic PASC differs by race/ethnicity and social drivers of health. Methods: We conducted a retrospective cohort study of individuals <21 years seeking care at 24 health systems across the U.S, using electronic health record (EHR) data. …”
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41009
Determinants of Uterine Rupture and Its Management Outcomes among Mothers Who Gave Birth at Public Hospitals of Tigrai, North Ethiopia: An Unmatched Case Control Study
Published 2020-01-01“…Although risk factors of uterine rupture are context specific, there is lack of clarity in our context towards the contributing factors and untoward outcomes of uterine rupture. This study was conducted to identify the risk factors of uterine rupture and its impacts in public hospitals of Tigrai. …”
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41010
Optimizing fodder yield and quality through integrated organic nutrient amendments in multi-crop system
Published 2025-02-01“…This study aims to investigate the effects of integrated organic nutrient amendments on the yield and quality of multi-crop system. Conducted during the period 2018 to 2021 using a randomized complete block design, the experiment encompassed seven treatments, each replicated three times. …”
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41011
The Influence of Edaphic and Climatic Factors on the Morphophysiological Behavior of Young Argan Plants Cultivated in Orchards: A Comparative Analysis of Three Regions in Southwest...
Published 2025-01-01“…The soil was analyzed for the pH, electrical conductivity (EC), water content, limestone (CaCO<sub>3</sub>), Kjeldahl nitrogen (N), available phosphorus (P<sub>2</sub>O<sub>5</sub>), organic matter (OM), and carbon/nitrogen ratio (C/N). …”
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41012
Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals
Published 2025-01-01“…These findings suggest that IN delivery of rAd5-SARS2-S1 could be a promising approach for inducing mucosal and systemic immunity, offering enhanced protection against SARS-CoV-2 and emerging variants.IMPORTANCEThis publication presents an assessment of the immune response and effectiveness of a vaccine containing genetically modified non-replicating recombinant that expresses the S1 subunit protein of SARS-CoV-2. We conducted a comparative analysis of the immune response potency, durability, and protective effectiveness of this vaccine using intramuscular (IM) and intranasal (IN) inoculation in mice and Syrian hamsters. …”
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41013
Overview: quasi-Lagrangian observations of Arctic air mass transformations – introduction and initial results of the HALO–(𝒜 𝒞)<sup>3</sup> aircraft campaign
Published 2024-08-01“…To collect data that help to constrain the models, the HALO–(<span class="inline-formula">𝒜𝒞</span>)<span class="inline-formula"><sup>3</sup></span> aircraft campaign was conducted over the Norwegian and Greenland seas, the Fram Strait, and the central Arctic Ocean in March and April 2022. …”
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41014
Newborn Screening Program for Cystic Fibrosis in Türkiye: Experiences from False-Negative Tests and Requirement for Optimization
Published 2025-01-01“…Methods: Screening for CF was conducted in accordance with the national CF-NBS program within 48-72 hours of birth by collecting a few drops of heel blood on Guthrie paper. …”
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41015
Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract
Published 2025-01-01“…Histopathologic review was conducted by independent pathologists. Relapse event was the time‐to‐event outcome, and relapse probabilities were estimated using a competing risk method with cumulative incidence functions (CIFs). …”
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41016
Post-acute sequelae of hospitalised COVID-19 re-infection compared with hospitalised first-time infection: a population-based retrospective cohort study in Hong Kong
Published 2025-01-01“…Subgroup analyses were conducted by age (<65 and ≥65 years), sex, Charlson Comorbidity Index (0–4, ≥5), COVID-19 vaccination (0–1, 2+doses) and hospitalisation status of previous infection.Results 2244 patients with hospitalised COVID-19 re-infection and 58 894 patients with hospitalised first-time COVID-19 infection were included. …”
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41017
HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals
Published 2024-10-01“…Methods This protocol describes a cluster randomized controlled trial (RCT) conducted among ESICM-affiliated ICUs, consisting of at least 73 clusters with in average of 50 respondents per cluster, totaling approximately 7300 participants. …”
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41018
Effects of nitrogen fertilizer basal-to-top-dressing ratios on maize straw decomposition, soil carbon and nitrogen, and bacterial community structure in different soil textures on...
Published 2025-02-01“…In a wheat–maize rotation system, field experiments were conducted over 2 years in loam and clay loam soils with five fertilizer (N) application treatments (i.e., no N fertilizer (N0) and N fertilizer basal-to-top-dressing ratios of 3:7 (N3:7), 4:6 (N4:6), 5:5 (N5:5), and 6:4 (N6:4)) to investigate the dynamics of maize straw decomposition, changes in soil organic carbon (SOC) and total nitrogen (TN) concentrations, soil bacterial diversity and abundance, and their interactions. …”
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41019
Enhanced fibrotic potential of COL1A1hiNR4A1low fibroblasts in ischemic heart revealed by transcriptional dynamics heterogeneity analysis at both bulk and single-cell levels
Published 2025-01-01“…The effectiveness and robustness of the gene-derived diagnostic tool were validated using two independent IHD cohorts.Subsequently, we validated the signature genes using a rat post-myocardial infarction heart failure model.ResultsWe conducted an analysis on high-quality snRNA-seq data obtained from 3 IHD and 4 cardiac sarcoidosis heart samples, resulting in the identification of 16 FB clusters. …”
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41020
Trends and Outcomes in Sarcomatoid Renal Cell Carcinoma: Analysis of the National Cancer Data Base
Published 2025-01-01“…Trend analyses were conducted using the Cochran-Armitage test. Multivariable analyses were used to assess factors associated with sRCC diagnosis and clinicopathologic characteristics associated with all-cause mortality (ACM). …”
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