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  1. 40101
  2. 40102

    Anlotinib in combination with metronomic chemotherapy in HER2-negative metastatic breast cancer: an observational and retrospective study by Jiaxuan Liu, Jiayang Zhang, Huiping Li, Guohong Song, Lijun Di, Hanfang Jiang, Ying Yan, Huan Wang, Jing Wang, Xiaoran Liu, Bin Shao, Qiao Li

    Published 2025-01-01
    “…Metronomic chemotherapy (MCT) provides antiangiogenic effects without increased toxicities, making it good partner for antiangiogenic therapy. We conducted the present retrospective study to evaluate the efficacy and safety of anlotinib plus MCT for HER2 negative MBC. …”
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  3. 40103

    Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit by Maitee Rosende-Roca, Fernando García-Gutiérrez, Yahveth Cantero-Fortiz, Montserrat Alegret, Vanesa Pytel, Pilar Cañabate, Antonio González-Pérez, Itziar de Rojas, Liliana Vargas, Juan Pablo Tartari, Ana Espinosa, Gemma Ortega, Alba Pérez-Cordón, Mariola Moreno, Sílvia Preckler, Susanna Seguer, Miren Jone Gurruchaga, Lluís Tárraga, Agustín Ruiz, Sergi Valero, Mercè Boada, Marta Marquié

    Published 2025-01-01
    “…To enhance our understanding of how sex influences the characteristics of AD patients and its potential impact on the disease trajectory, we conducted a comprehensive analysis of demographic, clinical, cognitive, and genetic data from a sizable and well-characterized cohort of AD dementia patients at a memory clinic in Barcelona, Spain. …”
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  4. 40104

    Tracheostomy Practice in the Italian Intensive Care Units: A Point-Prevalence Survey by Raffaele Merola, Maria Vargas, Filippo Sanfilippo, Marco Vergano, Giovanni Mistraletti, Luigi Vetrugno, Gennaro De Pascale, Elena Giovanna Bignami, Giuseppe Servillo, Denise Battaglini

    Published 2025-01-01
    “…<i>Materials and Methods</i>: We conducted an observational, cross-sectional, point-prevalence survey across eight ICUs in Italy. …”
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  5. 40105
  6. 40106

    Novel loci for triglyceride/HDL-C ratio longitudinal change among subjects without T2D by Lihua Wang, Siyu Wang, Jason A. Anema, Vaha A. Moghaddam, Yanli Lu, Shiow Lin, E. Warwick Daw, Allison L. Kuipers, Iva Miljkovic, Michael Brent, Gary J. Patti, Bharat Thygarajan, Joseph M. Zmuda, Michael A. Province, Ping An

    Published 2025-01-01
    “…To identify novel genetic loci for THR change over time (ΔTHR), we conducted genome-wide association study (GWAS) and genome-wide linkage scan (GWLS) among nondiabetic Europeans from the Long Life Family Study (n = 1,384). …”
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  7. 40107
  8. 40108
  9. 40109
  10. 40110

    Shedding light on the existence of Furan fatty acids in latex lipids across a wide diversity of Hevea brasiliensis genotypes by Chaisiri Kitpaosong, Siriluck Liengprayoon, Erwann Durand, Tucksin Lerksamran, Aurélie Daval, Eric Gohet, Lim Khan Tiva, Phean Chetha, Kong Mengchheang, Phen Phearun, Ung Rattana, Kim Chandy, Pol Sokea, Un Kim Eng, Kittipong Rattanaporn, Bruno Barea, Laurent Vaysse

    Published 2025-02-01
    “…Based on knowledge of the parentage of the studied clones, a trait heritability study was conducted and genotype PB5/51 was identified as a very worthwhile genitor for improving furan fatty acid contents in a breeding population.…”
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  11. 40111

    Potential Mechanisms and Effects of Dai Bai Jie Ethanol Extract in Preventing Acute Alcoholic Liver Injury by Niantong Xia, Hongwei Xue, Yihang Li, Jia Liu, Yang Lou, Shuyang Li, Yutian Wang, Juan Lu, Xi Chen

    Published 2024-12-01
    “…Mechanistic investigations were conducted using RT-qPCR assays and immunohistochemical analysis to determine the protective effects of DBJ. …”
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  12. 40112

    Loop33 × 123 CAR-T targeting CD33 and CD123 against immune escape in acute myeloid leukemia by Haotian Ma, Zhifeng Yan, Runxia Gu, Yingxi Xu, Shaowei Qiu, Haiyan Xing, Kejing Tang, Zheng Tian, Qing Rao, Min Wang, Jianxiang Wang

    Published 2024-11-01
    “…Coculture killing assays were conducted using various AML cell lines and primary AML cells. …”
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  13. 40113

    Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up by He Yin, Xin Chen, Zhiwei Liu, Zhiwei Liu, Bo Xu, Zhefeng Jin, Yan Liu, Baoyu Qi, Bin Tang, Ping Wang, Fanping Xu, Xu Wei, Jie Yu, Liguo Zhu, Liguo Zhu

    Published 2025-01-01
    “…ObjectiveThis randomized controlled trial aims to evaluate the efficacy and safety of Yishenyangsui granule for treating Degenerative Cervical Myelopathy.Materials and methodsA randomized, double-blind, placebo-controlled clinical trial was conducted with 152 participants recruited from three centers and randomly assigned to receive either Yishenyangsui granule or placebo. …”
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  14. 40114

    Deployment and uptake of COVID-19 vaccines for refugees and migrants in regular and irregular situations: a mixed-method multicountry study by Biraj Man Karmacharya, Karl Blanchet, Jai K Das, Laetitia Nyirazinyoye, Maria Midea M Kabamalan, Nguyen Toan Tran, Zahra A Padhani, Anjali Joshi, Seyed-Moeen Hosseinalipour, Enrique Teran, Pierina Benavente, Vinay N Kampalath, Moussa Lonkila Zan, Elżbieta Anna Czapka, Cheryl Martens, Vicente B Jurlano

    Published 2025-02-01
    “…This study aimed to identify barriers and facilitators and estimate vaccination coverage among refugees and migrants in low- and middle-income countries, emphasising inclusive policies for effective rollout.Methods A mixed-method study was conducted in two phases in Ecuador, Nepal, Pakistan, the Philippines and Rwanda. …”
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  15. 40115
  16. 40116

    Clinical and microbiological analyses of colistin-resistant strains among carbapenem-resistant Enterobacter cloacae complex clinical isolates by Jinyoung Yang, Jin Yang Baek, Jae-Hoon Ko, Kyungmin Huh, Sun Young Cho, Doo Ryeon Chung, Kyong Ran Peck, Hee Jae Huh, Kwan Soo Ko, Cheol-In Kang

    Published 2025-02-01
    “…Species identification was performed using hsp60 gene analysis, and antibiotic susceptibility tests were conducted by broth microdilution. The clinical characteristics of patients with CR-ECC isolates were retrospectively analyzed. …”
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  17. 40117
  18. 40118

    Genome-Wide Identification and Expression Analysis of bHLH-MYC Family Genes from Mustard That May Be Important in Trichome Formation by Jianzhong Li, Guoliang Li, Caishuo Zhu, Shaoxing Wang, Shifan Zhang, Fei Li, Hui Zhang, Rifei Sun, Lingyun Yuan, Guohu Chen, Xiaoyan Tang, Chenggang Wang, Shujiang Zhang

    Published 2025-01-01
    “…In this study, a total of 45 bHLH-MYC transcription factors were identified within the <i>Brassica juncea</i> genome, and a comprehensive series of bioinformatic analyses were conducted on their structures and properties: an examination of protein physicochemical properties, an exploration of conserved structural domains, an assessment of chromosomal positional distributions, an analysis of the conserved motifs, an evaluation of the gene structures, microsynteny analyses, three-dimensional structure prediction, and an analysis of sequence signatures. …”
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  19. 40119

    Balancing environmental impact: A sustainability index analysis of sorghum production for food and feed by A. Prabowo, R.N. Hayati, S. Minarsih, B. Haryanto, D.D. Ludfiani, A. Supriyo, S. Subiharta, E. Nurwahyuni, Y. Hindarwati, M.N. Setiapermas, S. Sudarto, S. Samijan, B. Utomo, E. Winarn, N.D. Suretno, W. Wibawa, S. Agustini, A. Prasetyo, F.R.P. Hantoro, W. Hariyanto, V.E. Aristya

    Published 2024-01-01
    “…Therefore, this study aimed to determine sustainability index and potential of sorghum for food and feed by identifying dimensions and attributes that influence sustainability.METHODS: This study was conducted at Raji, Demak, Central Java, Indonesia in 2023. …”
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  20. 40120

    Positive end-expiratory pressure increases intracranial pressure but not pressure reactivity index in supine and prone positions: a porcine model study by Rønnaug Hammervold, Rønnaug Hammervold, Rønnaug Hammervold, Erta Beqiri, Peter Smielewski, Benjamin S. Storm, Benjamin S. Storm, Benjamin S. Storm, Benjamin S. Storm, Erik W. Nielsen, Erik W. Nielsen, Erik W. Nielsen, Erik W. Nielsen, Erik W. Nielsen, Claude Guérin, Shirin K. Frisvold, Shirin K. Frisvold

    Published 2025-01-01
    “…An exploratory correlation analysis was conducted on baseline variables potentially related to the ICP increase.ResultsMean ICP increase was 1.0 mmHg ± 0.9 at 10 cmH2O PEEP, 2.0 mmHg ± 1.7 at 15 cmH2O PEEP, and 3.1 mmHg ± 1.6 at 20 cmH2O PEEP compared to a baseline PEEP of 5 cmH2O (p &lt; 0.001). …”
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