Protocol for the DisCoVeRy trial: multicentre, adaptive, randomised trial of the safety and efficacy of treatments for COVID-19 in hospitalised adults by Florence Ader, Jean-François Timsit, Yazdan Yazdanpanah, François-Xavier Lescure, Laetitia Moinot, Christelle Delmas, Hélène Espérou, Laurent Abel, Benjamin Leveau, Vinca Icard, Toni Alfaiate, Linda Wittkop, Charles Burdet, France Mentré, Marion Schneider, Nathan Peiffer-Smadja, Julien Poissy, Lila Bouadma, Bruno Lina, Florence Morfin-Sherpa, Maude Bouscambert, Alexandre Gaymard, Gilles Peytavin, Jeremie Guedj, Claire Andrejak, Cedric Laouenan, Drifa Belhadi, Axelle Dupont, Basma Basli, Anissa Chair, Samira Laribi, Julie Level, Marie-Capucine Tellier, Aline Dechanet, Dominique Costagliola, Sandrine Couffin-Cadiergues, Juliette Saillard, Claire Fougerou, Carole Cagnot, Soizic Le Mestre, Delphine Lebrasseur-Longuet, Ventzislava Petrov-Sanchez, Alpha Diallo, NoéMie Mercier, Sarah Tubiana, Benjamin Hamze, Ambre Gelley, Marion Noret, Eric D’Ortenzio, Oriane Puechal, Caroline Semaille

“…Since 5 April 2020, DisCoVeRy has been an add-on trial of the Solidarity consortium of trials conducted by the WHO in Europe and worldwide. On 8 June 2020, 754 patients have been included.Ethics and dissemination Inserm is the sponsor of DisCoVeRy. …”
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Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts by Arbi Guetat, Slimen Selmi, Abdelrhman T. Abdelwahab, Marwa A. Abdelfattah, Abd Ealrhman M. Elhaj, Roaa T. Mogharbel, M. J. A. Abualreish, Abdullah F. Alanazi, Karim Hosni, Naceur Mejri, Abdennacer Boulila

“…The identity of phenolic compounds of the hydroethanolic extract of S. deserti was conducted through HPLC-Electrospray Ionization-Mass Spectrometry (LC-ESI-MS) analyses.ResultsOral administration of hydroethanolic extract of S. deserti at 200 and 400 mg/kg for 14 days significantly decreased blood glucose and restored the hepatic and renal function by reducing the levels of ALT, AST, ALP, GGT, LDH, urea and creatinine. …”
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Preparation Methods and Perceived Risk of Foodborne Illness Among Consumers of Prepackaged Frozen Vegetables – United States, September 2022 by Michelle Canning, Michael Ablan, Tamara N. Crawford, Amanda Conrad, Alexandra Busbee, Misha Robyn, Katherine E. Marshall

“…During September 1–24, 2022, Porter Novelli Public Services conducted the FallStyles survey using the Ipsos KnowledgePanel. …”
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Exploring the Role of Radiosurgery for Atypical Meningiomas: Addressing Suboptimal Local Control in High-Risk Patients by Sanjeev Sreenivasan, MD, MCh, Salem Najjar, BA, Daniel Ma, MD, Sabrina L. Begley, BS, Yen-Ruh Wuu, MD, Zaker Rana, MD, Emile Gogineni, DO, Michael Schulder, MD, Anuj Goenka, MD

“…However, available data are limited. We aimed to conduct a comprehensive review of a consecutive cohort of patients diagnosed with high-risk atypical meningioma who underwent SRS, either as a single-fraction SRS or in the hypofractionated SRS (hf-SRS), and evaluate the LC rates (LCR) with a specific emphasis on patterns of treatment failure. …”
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Wealth-based inequalities in tuberculosis prevalence among households having children and young adults in India: insights from Indian demographic and health surveys (2015–2021) by Saurabh Singh, Quazi Syed Zahiruddin, Sorabh Lakhanpal, Suhas Ballal, Sanjay Kumar, Mahakshit Bhat, Shilpa Sharma, M Ravi Kumar, Yogesh Kumar Dhandh, Sarvesh Rustagi, Mohammed Alissa, Muhammad A. Halwani, Mohammed Garout, Hayam A Alrasheed, Maha F. Al-Subaie, Nawal A. Al Kaabi, Ali A. Rabaan, Sanjit Sah, Muhammed Shabil, Mahalaqua Nazli Khatib, Prakasini Satapathy

“…Data and methods Utilizing data from the National Family Health Survey (NFHS) 4th and 5th round (2015-16 and 2019-21), this study conducted a comprehensive cross-sectional analysis. …”
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Modulation of local immunity by the vaginal microbiome is associated with triggering spontaneous preterm birth by Yijia Liang, Yijia Liang, Yijia Liang, Changying Zhao, Yan Wen, Dashuang Sheng, Tiantian Wei, Tianqi Hu, Junhui Dai, Guoping Zhao, Guoping Zhao, Guoping Zhao, Sijie Yang, Sijie Yang, Qinghua Wang, Lei Zhang, Lei Zhang

“…Additionally, it sought to uncover the microbial composition and functional characteristics of immune states linked to preterm birth, and to evaluate the impact of bacterial interactions on the initiation of preterm birth.MethodsUtilizing 16S rRNA sequencing data and local immune factor expression data from a publicly available longitudinal pregnancy cohort, we conducted immunophenotyping through unsupervised clustering of the immune factors. …”
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Current data on the circulation of the Q fever pathogen in the Republic of Guinea by Ekaterina V. Naidenova, Kirill S. Zakharov, Dmitry A. Agafonov, Mikhail Yu. Kartashov, Aislu M. Senichkina, Erik S. Khalilov, Abdoul B. Ibrahim, Mamadou B. Bah, Ibrahim Nourdine, Nikolai K. Tokarevich, Sanaba Boumbaly, Yusuf Sidime, Svetlana A. Shcherbakova, Vladimir V. Kutyrev

“…In 1980–1990, the Soviet-Guinean Research Virology and Microbiology Laboratory conducted studies to estimate the distribution of the Q fever pathogen, assess the herd immunity in humans and identify specific antibodies in the sera of livestock. …”
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Associations of Retinal Microvascular Density and Fractal Dimension with Glaucoma: A Prospective Study from UK Biobank by Qi Chen, MD, Suyu Miao, MD, Yuzhe Jiang, MD, Danli Shi, MD, PhD, Weiyun You, MD, Lin Liu, MD, PhD, Mayinuer Yusufu, MTI, Yufan Chen, MD, Ruobing Wang, MD, PhD

“…Propensity score matching was implemented via a logistic regression model with a caliper of 0.1 and a matching ratio of 1:4 no replacements. We conducted univariable Cox regression analyses to study the association between retinal microvascular parameters and incident glaucoma, in both continuous and quartile forms. …”
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Emergency volunteering willingness and participation: a cross-sectional survey of residents in northern China by Hong Sun, Chaojie Liu, Wei Xu, Ye Li, Qunhong Wu, Lijun Gao, Zheng Kang, Yanhua Hao, Ning Ning, Mingli Jiao, Libo Liang, Yu Cui, Mengli Shi, Chao Liang, Xiaowen Zhao, Jie Fei, Qiuyu Wei, Ming Yi

“…Objectives This study aimed to identify factors that influence people’s willingness to volunteer and participation in emergency volunteering in northern China.Design/Setting This study was conducted in Heilongjiang province in September and October 2014 using a mixed methods approach, which included a cross-sectional questionnaire survey on community residents and in–depth interviews with community residents and relevant organisational managers and officials in relation to emergency responses. …”
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Oncological outcomes following extreme oncoplastic breast conserving surgery (eOPBCS) for locally advanced breast cancer (LABC): A systematic review and meta-analysis by Megan Chua Wern Ee, Ashley Lee Shi Hui, Wong Hung Chew, Emmeline Elaine Cua-Delos Santos, Sean Li Siwei, Sng Ming Xian, Qin Xiang Ng, Serene Goh Si Ning

“…Methods: A systematic review and meta-analysis were conducted following PRISMA guidelines (PROSPERO: CRD42024535182). …”
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Safety and feasibility of En‐bloc holmium laser enucleation for very large prostates (> 200 cc) with trainee involvement by Feres C. Maluf, Ansh Bhatia, Archan Khandekar, Diana M. Lopategui, Joao G. Porto, Ryan R. Chen, Jean C. Daher, Mohamadhusni Zarli, Robert Marcovich, Hemendra N. Shah

“…Patients and Methods A retrospective analysis was conducted on patients undergoing HoLEP using the “en‐bloc” technique for prostate sizes > 200 cc between July‐2017 and December‐2023 at an academic teaching hospital. …”
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Urban environment during pregnancy, cognitive abilities, motor function, and externalizing and internalizing symptoms at 2–5 years old in 3 Canadian birth cohorts by Anne-Claire Binter, Dany Doiron, Martine Shareck, Tona Pitt, Sheila W. McDonald, Padmaja Subbarao, Wiliam D. Fraser, Suzanne C. Tough, Jeffrey Brook, Mònica Guxens

“…We assessed associations of each environmental exposure indicator with each of the 6 outcomes, using multivariate linear regression models. We conducted analyses separately by city of recruitment and combined estimates in meta-analyses. …”
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Patterns and factors associated with healthcare utilisation in Cambodia: a cross-sectional study based on the World Health Survey Plus 2023 by Kerstin Klipstein-Grobusch, Por Ir, Paul Kowal, Nawi Ng, Srean Chhim, Chhorvann Chhea, Chamnab Ngor, Sereyraksmey Long, Poppy Walton, Khin Thiri Maung, Grace Marie Ku, Heng Sopheab

“…This study aims to describe patterns of public and private outpatient and inpatient healthcare use and investigate the factors associated with public healthcare usage in Cambodia.Method A cross-sectional study was conducted in all provinces in Cambodia, including the capital, Phnom Penh. …”
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Gut microbiota and inflammasome-mediated pyroptosis: a bibliometric analysis from 2014 to 2023 by Hang Zhang, Hang Zhang, Hang Zhang, Tian Zhao, Tian Zhao, Tian Zhao, Juan Gu, Juan Gu, Fushan Tang, Fushan Tang, Fushan Tang, Lei Zhu, Lei Zhu, Lei Zhu

“…Bibliometric analysis provides a comprehensive understanding of this relationship, offering valuable insights into emerging research trends.Materials and methodsLeveraging data spanning from 2014 to 2023 sourced from the Web of Science Core Collection, our analysis was conducted using advanced tools such as SCImago Graphica, VOSviewer, and CiteSpace software. …”
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Trends in stroke-related mortality in atrial fibrillation patients in the United States: Insights from the CDC WONDER database by Muhammad Abdullah Naveed, Sivaram Neppala, Himaja Dutt Chigurupati, Muhammad Omer Rehan, Ahila Ali, Hamza Naveed, Bazil Azeem, Rabia Iqbal, Manahil Mubeen, Mashood Ahmed, Ayman R. Fath, Timir Paul, Bilal Munir

“…Methods: A retrospective analysis was conducted to acquire death data using the Centers for Disease Control and Prevention database from 1999 to 2020. …”
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Appetite Suppression and Antiobesity Effect of a Botanical Composition Composed of Morus alba, Yerba mate, and Magnolia officinalis by Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Eu-Jin Hyun, Hyun-Jin Kim, Tae-Woo Kim, Jeong-Bum Nam, Mi-Ran Kim, Qi Jia

“…Nonalcoholic steatohepatitis (NASH) scoring was conducted. Results. Marked acute hypophagia with 81.8, 75.3, 43.9, and 30.9% reductions in food intake at 2, 4, 6, and 24 hours were observed for UP601. …”
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Prevalence and factors associated with neonatal sepsis in Mali: a cross-sectional study by Bienvenu Salim Camara, Alexandre Delamou, Haoua Dembele, Hamadoun Sangho, Birama Apho Ly, Sidikiba Sidibé, Alioune Camara, Cheick Sidya Sidibé, Alhassane Diallo, Abdoulaye Touré, Fatoumata Bintou Traoré, Elhadj Marouf Diallo, Fatimata Yaro, Mariam Traoré

“…Data were analyses using bivariate and multivariate logistic regression.Setting This facility-based study was conducted in four health facilities consisting of two hospitals and two reference health centres in Mali.Participants The study participants comprised 795 randomly selected neonates and their indexed mother.Outcome measures The primary outcome of the study was the prevalence of sepsis in the considered health facilities. …”
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Time-varying intensity of ventilatory inefficiency and mortality in patients with acute respiratory distress syndrome by Lianlian Jiang, Hui Chen, Wei Chang, Qin Sun, Xueyan Yuan, Zongsheng Wu, Jianfeng Xie, Ling Liu, Yi Yang

“…This study aims to investigate the relationship between 28-day mortality in ARDS patients and their longitudinal exposure to ventilatory inefficiency, as reflected by serial measurements of PaCO2 and VR. Methods We conducted a secondary analysis of four randomized controlled trials (FACTT, ALTA, EDEN, and SAILS) from the ARDS Network. …”
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Passive exposure and perceptions of smoke-free policies in hospital and university campuses among nursing students: A cross-sectional multicenter study by Marcela Fu, Yolanda Castellano, Kenza Laroussy, Antoni Baena, Mercè Margalef, Ariadna Feliu, Jordi Galimany-Masclans, Montse Puig-Llobet, Carmen Moreno-Arroyo, Raül Sancho, Albert Bueno, Antonio López, Joseph Guydish, Esteve Fernández, Cristina Martínez

“…Methods This was a cross-sectional multicenter study conducted in 2015–2016 in all 15 university nursing schools in Catalonia, Spain. …”
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Comparison of the adequacies of the OSCE and vOSCE to assess the competencies required under Brazilian medical curriculum guidelines: a multicenter study by Hervaldo Sampaio Carvalho, Maria do Carmo Barros Melo, Fabiana Maria Kakehasi, Priscila Menezes Ferri Liu, Fernanda Gontijo Minafra Silveira Santos, Ricardo Luiz de Melo Martins, Marilene Vale de Castro Monteiro, Marcelo Esteves Chaves Campos, Roberto Zonato Esteves, Matheus Belloni Torsani, Iolanda de Fátima Lopes Calvo Tiberio, Akihito Inca Atahualpa Urdiales, Andrea Mora De Marco Novellino, Rosiane Viana Zuza Diniz, Helena Ferreira Moura, Maria Alice de Vilhena Toledo, Célia Regina Machado Saldanha, Andrea Pedrosa Ribeiro Alves Oliveira, Patricia Zen Tempski, Itamar de Souza Santos, Milton de Arruda Martins

“…It is necessary to invest in the creation of instruments that can be used to apply the vOSCE and to conduct cost‒benefit analysis of its broader application in health education institutions. …”
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