Small extracellular vesicles derived from sequential stimulation of canine adipose-derived mesenchymal stem cells enhance anti-inflammatory activity by Saranyou Oontawee, Parkpoom Siriarchavatana, Watchareewan Rodprasert, Irma Padeta, Yudith Violetta Pamulang, Poorichaya Somparn, Trairak Pisitkun, Boondarika Nambooppha, Nattawooti Sthitmatee, Daneeya Na Nan, Thanaphum Osathanon, Hiroshi Egusa, Chenphop Sawangmake

“…To validate the efficacy of IVES for sEV production, various analyses were conducted, including microscopic examination, surface marker assessment, zeta-potential measurement, protein quantification, nanoparticle tracking analysis, and determination of anti-inflammatory activity. …”
Get full text

Aetiology of chronic liver disease is a valuable factor for stratifying adverse outcomes of acute decompensation: prospective observational study by Jung Hee Kim, Sung-Eun Kim, Do Seon Song, Hee Yeon Kim, Eileen L. Yoon, Ji Won Park, Tae Hyung Kim, Young-Kul Jung, Ki Tae Suk, Hyung Joon Yim, Jung Hyun Kwon, Sung Won Lee, Seong Hee Kang, Moon Young Kim, Soung Won Jeong, Jae-Young Jang, Jeong Ju Yoo, Sang Gyune Kim, Young-Joo Jin, Gab Jin Cheon, Byung Seok Kim, Yeon Seok Seo, Hyoungsu Kim, Dong Hyun Sinn, Woo Jin Chung, Hwi Young Kim, Han Ah Lee, Seung Woo Nam, In Hee Kim, Ji Hoon Kim, Hee Bok Chae, Joo Hyun Sohn, Ju Yeon Cho, Yoon Jun Kim, Jin Mo Yang, Jung Gil Park, Won Kim, Hyun Chin Cho, Dong Joon Kim

“…However, limited research has been conducted to analyse these discrepancies across aetiologies.Methods The prospective Korean Acute-on-Chronic Liver Failure (KACLiF) cohort consisted of 1,501 patients who were hospitalized with AD of CLD from July 2015 to August 2018. …”
Get full text

Mesenchymal stem cell-mediated adipogenic transformation: a key driver of oral squamous cell carcinoma progression by Yiting Shao, Yu Du, Zheng Chen, Lei Xiang, Shaoqin Tu, Yi Feng, Yuluan Hou, Xiaoxing Kou, Hong Ai

“…Subcutaneous xenograft experiments were conducted in BALB/c-nu mice to further investigate the effects in vivo. …”
Get full text

The use of patient-generated health data in the management of low anterior resection syndrome: a qualitative study by Olivia Monton, Olivia Monton, Allister Smith, Sarah Sabboobeh, Marie Demian, Julie Cornish, Steven D. Wexner, Peter Christensen, Peter Christensen, Amandeep Ghuman, Liliana G. Bordeianou, Liliana G. Bordeianou, Liliana G. Bordeianou, Celia Keane, Celia Keane, Syed Husain, Alessandra Gasior, Alessandra Gasior, Natalie Leon, Julie Savard, Lieba R. Savitt, Margit Majgaard, Gitte Kjær Sørensen, Melanie Mills, Fateme Rajabiyazdi, Marylise Boutros, Marylise Boutros

“…The objective of this study was to explore the perspectives and experiences of LARS experts regarding the use of PGHD in the management of LARS.MethodsWe utilized purposive snowball sampling to identify international LARS experts, including surgeons, nurses, and LARS researchers with knowledge and expertise in LARS. We conducted individual semi-structured interviews with these experts between August 2022 and February 2024. …”
Get full text

Investigation of the Prevalence of Infectious Myonecrosis Virus (IMNV) from 2022 to 2023 by Ruidong XU, Jitao XIA, Ping LI, Xingtong YU, Liang YAO, Wenqiang LI, Tianchang JIA, Qingli ZHANG

“…To understand the prevalence of Chinese IMNV in recent years, an epidemiological survey of IMNV was conducted in major Chinese shrimp farming areas between 2022–2023. …”
Get full text

Social disconnectedness, subsequent medical conditions, and, the role of pre-existing mental disorders: a population-based cohort study by L. M. Laustsen, M. Lasgaard, N. C. Momen, D. Chen, J. L. Gradus, M. S. Grønkjær, M. M. Jensen, O. Plana-Ripoll

“…However, evidence is limited by a disease-specific focus and no systematic examination of sex differences or the role of pre-existing mental disorders. Methods We conducted a cohort study using data on social disconnectedness (loneliness, social isolation, low social support and a composite measure) from the 2013 and 2017 Danish National Health Survey linked with register data on 11 broad categories of medical conditions through 2021. …”
Get full text

The relationship between impostor phenomenon and emotional exhaustion among Chinese nurses: the mediating role of bi-directional work-family conflict by Yuan Li, Yuan Li, Yuan Li, Fangxinrui Qiu, Biru Luo, Biru Luo, Yanling Hu, Yanling Hu, Yanling Hu, Jie Li, Ying Xin Li, Ying Xin Li, Ying Xin Li, Ping He, Jinbo Fang

“…AimsThe study aims to explore the relationship between impostor phenomenon and emotional exhaustion among nurses and to examine the potential mediating role of bi-directional work–family conflict.MethodsA cross-sectional survey using convenience sampling was conducted from January to April 2023, involving 4,088 Chinese nurses. …”
Get full text

Clinical characteristics, outcomes, and costs of COVID-19 patients in Thai hospitels: a comparative analysis based on chest X-ray findings by Naruemit Sayabovorn, Pochamana Phisalprapa, Weerachai Srivanichakorn, Thanet Chaisathaphol, Chaiwat Washirasaksiri, Tullaya Sitasuwan, Chonticha Auesomwang, Chayanis Kositamongkol, Pongpol Nimitpunya, Teerapat Attachitwatin, Methee Chayakulkeeree, Pakpoom Phoompoung, Cherdchai Nopmaneejumruslers, Tawatchai Taweemonkongsap, Visit Vamvanij, Rungsima Tinmanee

“…This study evaluated the clinical characteristics, outcomes, and admission costs of asymptomatic and mild-to-moderate COVID-19 patients treated in these facilities. Methods We conducted a retrospective analysis of adult COVID-19 patients who were admitted between July and October 2021 to two hospitels in Bangkok that were affiliated with Siriraj Hospital. …”
Get full text

Treatment outcomes and its associated factors among neonates admitted with sepsis in Hiwot Fana Comprehensive Specialized University Hospital, Harar, Ethiopia by Betelhem Gezahegn, Ahmed Abdella, Fentahun Meseret, Ahmed Mohammed, Mulualem Keneni, Tesfaye Asfaw, Diribsa Tizazu, Assefa Desalew

“…Hence, the study aimed to assess outcomes and prognostic factors of sepsis among neonatal patients admitted to the neonatal intensive care unit in Hiwot Fana Comprehensive Specialized University Hospital in Ethiopia.MethodsA facility-based cross-sectional study was conducted among 311 neonates with sepsis admitted from 1 January 2021 to 30 December 2023. …”
Get full text

First-Line Chemo-Immunotherapy in SCLC: Outcomes of a Binational Real-World Study by Laura Moliner, MD, Núria Zellweger, MSc, Sabine Schmid, MD, Martina Bertschinger, MD, Christine Waibel, MD, Ferdinando Cerciello, MD, PhD, Patrizia Froesch, MD, Michael Mark, MD, Adrienne Bettini, MD, Pirmin Häuptle, MD, Veronika Blum, MD, Lisa Holer, MSc, Stefanie Hayoz, PhD, Martin Früh, MD, Samreen Ahmed, FRCP, MD, MBBS, MSc, Shradha Bhagani, MD, Nicola Steele, MD, Hannah-Leigh Gray, BSc, Stephen D. Robinson, MD, Michael Davidson, MD (Res), Samantha Cox, MD, MSc, MBBCh, Taha Khalid, MD, Tom R. Geldart, MD, Luke Nolan, FRCS, PhD, Deborah C. Scott, MBChB (MRCP), Lindsay Hennah, MD, Tom Newsom-Davis, MD, PhD, Emma Rathbone, MD, PhD, Catherine Handforth, MD, Arshi Denton, MD, Shairoz Merchant, PhD, Fiona Blackhall, MD, PhD, Laetitia A. Mauti, MD, Raffaele Califano, MD, Sacha I. Rothschild, MD, PhD

“…Methods: A retrospective binational multicenter study was conducted, involving consecutive patients with ES-SCLC from 10 British and 10 Swiss institutions. …”
Get full text

Effectiveness of an online food shopping intervention to reduce salt purchases among individuals with hypertension – findings of the SaltSwitch Online Grocery Shopping (OGS) random... by Jason HY Wu, Damian Maganja, Liping Huang, Kathy Trieu, Fraser Taylor, Eden M. Barrett, Clare Arnott, Xiaoqi Feng, Aletta E. Schutte, Gian Luca Di Tanna, Cliona Ni Mhurchu, Adrian J. Cameron, Mark D. Huffman, Bruce Neal

“…Methods This trial was conducted among individuals with hypertension who shopped for their groceries online in Australia. …”
Get full text

Comparison of demographic, clinical and laboratory characteristics between first and second COVID-19 waves in a secondary care hospital in Qatar: a retrospective study by Prem Chandra, Vamanjore A Naushad, Nishan K Purayil, Abazar Ahmad M Saeed, Pradeep Radhakrishnan, Irfan Varikkodan, Joe V Mathew, Jaseem Sirajudeen, Riyadh A Hammamy, Ahmad M Badi, Aasir M Suliman, Mohamed N Badawi, Saket Arya, Maryam AlMotawa, Aisha Al-Baker, Rania Alatom, Anand Kartha

“…Objective To compare the patient profile and outcomes in Qatar during the first and second waves of the COVID-19 pandemic.Setting A retrospective observational study was conducted comparing the demographic, clinical and laboratory characteristics of patients with COVID-19 infection admitted to a secondary care hospital, during the first and second waves of the pandemic.Participants 1039 patients from the first wave and 991 from the second wave who had pneumonia on chest X-ray and had a confirmed SARS-CoV-2 infection by a real-time PCR test of a nasopharyngeal swab were included. …”
Get full text

Percutaneous coronary intervention vs. medical therapy in patients on dialysis with coronary artery disease in China by Enmin Xie, Yaxin Wu, Zixiang Ye, Yong He, Hesong Zeng, Jianfang Luo, Mulei Chen, Wenyue Pang, Yanmin Xu, Chuanyu Gao, Xiaogang Guo, Lin Cai, Qingwei Ji, Yining Yang, Di Wu, Yiqiang Yuan, Jing Wan, Yuliang Ma, Jun Zhang, Zhimin Du, Qing Yang, Jinsong Cheng, Chunhua Ding, Xiang Ma, Chunlin Yin, Zeyuan Fan, Qiang Tang, Yue Li, Lihua Sun, Chengzhi Lu, Jufang Chi, Zhuhua Yao, Yanxiang Gao, Changan Yu, Jingyi Ren, Jingang Zheng, Rongman Jia

“…This multicenter, retrospective study was conducted in 30 tertiary medical centers across 12 provinces in China from January 2015 to June 2021 to include patients on dialysis with CAD. …”
Get full text

Active and Passive Smoking as Catalysts for Cognitive Impairment in Rural Indonesia: A Population-based Study by Faizal Muhammad, Afifah Syifaul Ummah, Farida Aisyah, Rivan Danuaji, Diah Kurnia Mirawati, Subandi Subandi, Baarid Luqman Hamidi, Ervina Arta Jayanti Hutabarat, Reviono Reviono, Yulie Erida Nur Rahmawati, Isa Ridwan

“…Methods: This population-based two-year survey was conducted in four rural public health centers from 2021 to 2023 in Central Java, Indonesia, each center caters to approximately 30 000 people. …”
Get full text

A new approach for evaluating regional permafrost changes: A case study in the Hoh Xil on the interior Qinghai‒Tibet Plateau by Yu-Xin Zhang, Lin Zhao, Chang-Wei Xie, Guo-Jie Hu, Shu-Hua Yang, De-Fu Zou, Yong-Ping Qiao, Xiang-Fei Li, Jia-Jie Peng

“…Centred on a transient heat conduction permafrost model, this approach was applied to the Qinghai Hoh Xil National Nature Reserve (referred to as Hoh Xil) within the QTP from 1960 to 2015, using the rate of air temperature change provided by the Wudaoliang Meteorological Station, the only national station in Hoh Xil. …”
Get full text

Predictive markers of rapid disease progression and chemotherapy resistance in triple-negative breast cancer patients following postoperative adjuvant therapy by Tao Ma, Xiao-meng Hao, Hong-dan Chen, Min-hui Zheng, Xiao-geng Chen, Shuang-Long Cai, Jin Zhang

“…A retrospective evaluation was conducted on 2294 TNBC patients who underwent surgery at Tianjin Medical University Cancer Hospital. …”
Get full text

Screened of long non-coding RNA related to wool development and fineness in Gansu alpine fine-wool sheep by Zhaohua He, Fangfang Zhao, Hongxian Sun, Jiang Hu, Jiqing Wang, Xiu Liu, Mingna Li, Zhiyun Hao, Zhidong Zhao, Bingang Shi, Feiyan Liu, Shaobin Li

“…In this research, we conducted a thorough analysis and characterization of the microstructure of wool, along with long non-coding RNAs (lncRNAs), their target genes, associated pathways, and Gene Ontology terms pertinent to the wool fineness development. …”
Get full text

Genome-wide association study of the antibody response to <i>Corynebacterium pseudotuberculosis</i> in sheep by J. Kyselová, L. Tichý, J. Marková, A. Gurgul, Z. Sztankóová, K. Vališ, S. Šlosárková, K. Kavanová, M. Beinhauerová, T. Szmatola, T. Szmatola

“…A case–control GWAS including 143 seropositive and 178 seronegative sheep was conducted to assess the relationship between the sheep genome and the antibody response to a phospholipase D antigen of <i>C. pseudotuberculosis</i> using GCTA software. …”
Get full text

Real-world outcomes of prophylactic cranial irradiation utilization and efficacy for patients with extensive-stage small cell lung cancer treated with consolidative thoracic radiot... by Abdul H. Lone, Rohan Salunkhe, Vijithan Sugumar, Luna J. Zhan, Xiang Y. Ye, Andrea Bezjak, John Cho, Meredith E. Giuliani, Andrew J. Hope, Alexander Sun, Srinivas Raman, Penelope A. Bradbury, Lawson Eng, Natasha B. Leighl, Frances A. Shepherd, Adrian Sacher, Geoffrey Liu, Benjamin H. Lok

“…Methods: A retrospective analysis of ES-SCLC patients without brain metastases who were all treated with CTRT between 2013–2021 at our institution was conducted. Overall survival (OS) and incidence of brain failure (BFR) were estimated using Kaplan-Meier estimation and cumulative incidence function. …”
Get full text

Characterization of three novel Helicobacter species infecting stomachs of dogs and cats: Helicobacter gastrocanis sp. nov., Helicobacter gastrofelis sp. nov., and Helicobacter fel... by Emiko Rimbara, Sae Aoki, Masato Suzuki, Hirotaka Kobayashi, Taisuke Nakagawa, Yuko Goto-Koshino, Sachiyo Nomura, Sachiyo Nomura, Wan-Ying Du, Hidenori Matsui, Shigetarou Mori, Keigo Shibayama, Tsuyoshi Kenri, Koichi Ohno

“…In the present study conducted in Japan, among the nine Helicobacter strains that we isolated from dogs and cats, NHP19-003T from a dog, and strains NHP19-012T and NHP21-005T from cats were identified to be the strains most closely related to Helicobacter heilmannii ASB1T based on a 16S rRNA comparison (98.7–99.2% similarity with H. heilmannii ASB1T). …”
Get full text