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39401
Longitudinal associations between air pollution and incident dementia as mediated by MRI-measured brain volumes in the UK Biobank
Published 2025-01-01“…Structural brain MRI was conducted from 2014 to 2022, with brain volumes relevant to dementia identified a priori. …”
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39402
Distribution and environmental drivers of macrofaunal nematode communities across gradients of methane seepage at cold seeps on Hikurangi Margin (New Zealand) and potential implica...
Published 2025-01-01“…Cold seeps are areas characterised by specialized biological communities that rely on chemosynthesis for their nutrition. To date, research conducted on New Zealand’s Hikurangi Margin seep communities has focused on communities at 650-1200 m water depth. …”
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39403
Global insights into MRSA bacteremia: a bibliometric analysis and future outlook
Published 2025-01-01“…Therefore, reviewing research on MRSA BSIs is crucial.MethodsThis study conducted a bibliometric analysis, retrieving and analyzing 1,621 publications related to MRSA BSIs from 2006 to 2024. …”
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39404
Bone metastasis in differentiated thyroid cancer: Spanish multicenter study of clinical characteristics, survival and prognostic factors
Published 2024-11-01“…ObjectiveThis study describes the characteristics, survival and prognostic factors in a cohort of patients with bone metastases (BM) from differentiated thyroid carcinoma (DTC).MethodsThis was a multicenter retrospective observational study conducted in Spain, including patients diagnosed with DTC and BM between 1980 and 2022. …”
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39405
The Minimum Dietary Diversity For Women Indicator Can Be Extended To Children And Adolescents aged 4-15 Years As A Proxy Population Indicator For Good Micronutrient Adequacy Of Die...
Published 2025-01-01“…Objectives: This study aims to validate FGS-10 and its related cutoffs against micronutrient intake adequacy in 4–15-y-old children/adolescents in LMICs. Methods: We conducted a secondary data analysis of 9 datasets of repeated 24-h recalls or weighed records including 11,524 children/adolescents aged 4–15 y, collected in 7 countries (Burkina Faso, Ghana, Ecuador, India, Malawi, Uganda, and Zambia) between 2007 and 2022. …”
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39406
Exploring the pivotal variables of tongue diagnosis between patients with chronic kidney disease and health participants
Published 2025-01-01“…This study examines the relationship between tongue characteristics and CKD severity using an automatic tongue diagnosis system (ATDS), which captures tongue images non-invasively to provide objective diagnostic information.MethodsThis cross-sectional, case-control study was conducted from July 1, 2019, to December 31, 2021. …”
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39407
Annotation and characterization of immunoglobulin loci and CDR3 polymorphism in water buffalo (Bubalus bubalis)
Published 2025-01-01“…The Igκ locus, located on chromosome 12, encompasses 24 Vκ genes, 5 Jκ genes, and 1 Cκ gene, while the Igλ locus on chromosome 17 includes 71 Vλ genes, 3 Jλ genes, and 3 Cλ genes. We also conducted a detailed examination of the buffalo IgH CDR3 repertoire, revealing the presence of ultra-long CDR3 sequences, a biased usage of certain V genes, and a high-frequency usage of IgHJ1-4 genes. …”
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39408
Low transthyretin is associated with the poor prognosis of colorectal cancer
Published 2025-02-01“…Cox proportional hazard regression analysis was conducted to evaluate the correlation between the TTR and the cumulative incidence of cancer-specific survival (CSS). …”
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39409
Lymphocyte-C-reactive protein ratio upon admission to predict disease progression and ICU admission in adult patients with diabetic ketoacidosis
Published 2025-01-01“…A single-center retrospective study was conducted, including adult DKA patients admitted to the First Affiliated Hospital of Harbin Medical University between March 2018 and March 2023. …”
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39410
Safety and Efficacy of Subcutaneous Rituximab in Previously Untreated Patients with CD20+ Diffuse Large B-Cell Lymphoma or Follicular Lymphoma: Results from an Italian Phase IIIb S...
Published 2022-01-01“…This report presents the results of a phase IIIb study conducted in Italy. The study included adult patients with CD20+ DLBCL or FL having received at least one full dose of IV RTX 375 mg/m2 during induction or maintenance. …”
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39411
Differences in carbon and nitrogen metabolism of soft japonica rice in southern China during grain filling stage under different light and nitrogen fertilizer conditions and their...
Published 2025-01-01“…To address this gap, field experiments were conducted under varying light intensities and nitrogen fertilizer levels to investigate the changes in carbon and nitrogen metabolism during grain filling, the eating quality of rice at maturity, and the relationship between them. …”
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39412
Single-cell transcriptome-wide Mendelian randomization and colocalization reveals immune-mediated regulatory mechanisms and drug targets for COVID-19Research in context
Published 2025-03-01“…Limited effective immune-mediated antiviral drugs have been launched. Methods: We conducted a Mendelian randomization (MR) and colocalization analysis using 26,597 single-cell expression quantitative trait loci (sc-eQTL) to proxy effects of expressions of 16,597 genes in 14 peripheral blood immune cells and tested them against four COVID-19 outcomes from COVID-19 Genetic Housing Initiative GWAS meta-analysis Round 7. …”
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39413
ESAT-6 protein suppresses allograft rejection by inducing CD4+Foxp3+ regulatory T cells through IκBα/cRel pathway
Published 2025-01-01“…Flow cytometric analyses were conducted to quantify CD4+Foxp3+ Tregs, while immunohistochemistry was carried out to observe allograft immunopathology. …”
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39414
Overview of systematic reviews on strategies to improve treatment initiation, adherence to antiretroviral therapy and retention in care for people living with HIV: part 1
Published 2020-09-01“…Objectives We sought to map the evidence and identify interventions that increase initiation of antiretroviral therapy, adherence to antiretroviral therapy and retention in care for people living with HIV at high risk for poor engagement in care.Methods We conducted an overview of systematic reviews and sought for evidence on vulnerable populations (men who have sex with men (MSM), African, Caribbean and Black (ACB) people, sex workers (SWs), people who inject drugs (PWID) and indigenous people). …”
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39415
Automatic vessel segmentation and reformation of non-contrast coronary magnetic resonance angiography using transfer learning-based three-dimensional U-net with attention mechanism
Published 2025-01-01“…Furthermore, an independent clinical evaluation was conducted on an additional cohort of 70 patients. The AI model's performance in segmenting coronary arteries was assessed using the Dice similarity coefficient (DSC) and recall. …”
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39416
Association of ambient temperature with social isolation among the community-dwelling Chinese older adults: A cross-sectional study in Hong Kong
Published 2025-01-01“…Methods: We took advantage of a cross-sectional survey conducted between January 2017 and November 2018 from a community service program special for older adults aged ≥60 who lived in a central community of Hong Kong. …”
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39417
Interaction between 24 h Urinary Free Cortisol and Obesity in Hypertension-Mediated Organ Damage in Patients with Untreated Hypertension
Published 2025-01-01“…Multivariate logistic regression was conducted to evaluate the associations of HMOD indicators with 24 h UFC and obesity. …”
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39418
Association of exposure to second-hand smoke during childhood with blood DNA methylation
Published 2025-01-01“…To address this gap, we conducted epigenome-wide meta-analyses to identify associations of postnatal SHS and child blood DNAm. …”
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39419
Oral human papillomavirus (HPV) prevalence and genotyping among healthy adult populations in the United States and Europe: results from the PROGRESS (PRevalence of Oral hpv infecti...
Published 2025-01-01“…Methods: The cross-sectional study was conducted between November 2020 and July 2023 in 105 dental offices in France, Germany, Spain, the United Kingdom (UK) and US. …”
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39420
Transition metal-based MOFs for Fenton-like photocatalytic degradation of organic pollutants: Performance, stability, and biocompatibility
Published 2025-01-01“…The proposed mechanism involves ligand-to-metal charge transfer (LMCT) and Fe-driven generation of reactive oxygen species (ROS) such as hydroxyl radicals. In vitro studies conducted on human monocytes (THP-1), murine embryonic fibroblasts (MEF-NF), breast cancer cells (4T1), melanoma cells (B16-F10), and colorectal cancer cells (CT26) demonstrated high biocompatibility of the developed MOFs. …”
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