The management and clinical outcome of paracetamol poisoning in South African adults: A single-centre retrospective review by C Kotze, J Swanepoel, E C Kruger, E Decloedt

“…A retrospective medical record review was conducted of all adult patients (≥18 years old) admitted between August 2013 and August 2018 to a tertiary referral centre in Cape Town, SA, with paracetamol poisoning and biochemical evidence of liver impairment. …”
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Knowledge, attitude and practice regarding screening and managing diabetic microvascular complications among general practitioners of community health centres: a cross-sectional st... by Hua Yang, Jian Gao, Ying Yu, Cuiling Huang, Chengdian Lan, Zhangyan Chen

“…Objective To evaluate the knowledge, attitude and practice (KAP) regarding screening and managing diabetic microvascular complications, encompassing diabetic retinopathy (DR), diabetic kidney disease (DKD) and diabetic neuropathy (DN), among general practitioners (GPs).Design Cross-sectional study.Setting The online questionnaire survey was conducted between April and July 2023.Participants GPs from community health centres (CHCs) in all 16 districts of Shanghai were recruited.Primary and secondary outcome measures The data of sociodemographic characteristics, KAP scales, training experience and screening instruments for community screening and managing diabetic microvascular complications were collected. …”
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Short-term and long-term effect of non-pharmacotherapy for adults with ADHD: a systematic review and network meta-analysis by Xinyue Yang, Lin Zhang, Jing Yu, Meng Wang

“…Nevertheless, the comparative efficacy of these interventions, particularly with respect to diverse ADHD-related outcomes and their long-term impacts, remains insufficiently investigated.ObjectiveThis study aims to evaluate and compare the short-term and long-term effects of various non-pharmacological therapies on core ADHD symptoms (inattention, hyperactivity, and impulsivity) and emotional disorders (depression and anxiety) in adults with ADHD and to rank these therapies accordingly.MethodsA systematic search was conducted for relevant randomized controlled trials (RCTs) in the Web of Science, PubMed, Cochrane Library, and EMBASE databases from inception to Sep 2024. …”
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Pengaruh Media Promosi Kesehatan tentang ASI Eksklusif terhadap Peningkatan Pengetahuan Ibu di Wilayah Kerja Puskesmas Lubuk Begalung Padang Tahun 2014 by Binarni Suhertusi, Desmiwarti ., Emi Nurjasmi

“…This was a quasi-experimental study with pretest-posttest group design. This study was conducted in the area of Lubuk Begalung health center Padang in 2014. …”
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Taenia solium taeniosis and cysticercosis literature in Tanzania provides research evidence justification for control: A systematic scoping review. by Helena Aminiel Ngowi, Andrea Sylvia Winkler, Uffe Christian Braae, Robinson Hammerthon Mdegela, Ernatus Martin Mkupasi, Mwemezi Lutakyawa Kabululu, Faustin Peter Lekule, Maria Vang Johansen

“…<h4>Methodology/principal findings</h4>A scoping review of all TSTC studies undertaken in Tanzania and published up to December 2018 was conducted. The articles were searched from PUBMED, AJOL, Google Scholar and Google in general. …”
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Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development by Baranasic Jurica, Niazi Yasmeen, Chattopadhyay Subhayan, Rumora Lada, Ćorak Lorna, Dugac Andrea Vukić, Jakopović Marko, Samaržija Miroslav, Försti Asta, Knežević Jelena

“…We also identified two SNPs located in the IL2RA gene associated with LC (rs2386841; p = 1.86 × 10−4) and COPD (rs11256442; p = 9.79 × 10−3) but with lower significance. Functional studies conducted on COPD patients showed that RNA expression of IL2RA, IFNγ and related proinflammatory cytokines in blood serum did not correlate with a specific genotype. …”
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Perinatal outcomes and predictors of placental abruption: a retrospective study in an Ethiopian tertiary care center by Mesfin Tadese, Gebresenbet Getachew, Tirusew Nigussie Kebede, Toyba Ebrahim Yesuf, Saba Desta Tessema, Wogene Asefa Damesa, Gebeyehu Shumet Solomon

“…Thus, the study aimed to investigate the adverse perinatal outcomes of placental abruption and the factors associated with these outcomes among pregnant women admitted to the University of Gondar Comprehensive Specialized Hospital in Ethiopia.MethodAn institution-based retrospective cross-sectional study was conducted among 367 pregnant women who were admitted and managed for placental abruption from January 1, 2021, to January 1, 2023, at the University of Gondar Comprehensive Specialized Hospital. …”
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Poor sleep quality remains a major challenge among tertiary education students in Ghana: A cross-sectional study in a Ghanaian University by David Larbi Simpong, Ansumana Bockarie, Akosua Bema Kumah, Alex Bismark Atta-Owusu, Mordecai Eshun, Bernice Akua Frimpong, Beatrice Bachella, George Nkrumah Osei

“…Methodology: A cross-sectional study was conducted to assess sleep quality using the validated Pittsburgh Sleep Quality Index among 295 undergraduate students at the University of Cape Coast, Ghana. …”
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Factors Affecting Nonadherence to WHO’s Recommended Antenatal Care Visits among Women in Pastoral Community, Northeastern Ethiopia: A Community-Based Cross-Sectional Study by Kusse Urmale Mare, Abel Gebre Wuneh, Mubarek Shemsu Awol, Mohammed Ahmed Ibrahim, Molla Kahsay Hiluf, Setognal Birara Aychiluhm, Osman Ahmed Mohammed, Kebede Gemeda Sabo

“…A community-based cross-sectional study was conducted from 04 February to 22 March 2020 among randomly selected 703 women who gave birth within 24 months preceding the survey in the Transform HDR districts of the Afar region. …”
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Mechanism of <italic>Coptis chinensis</italic> in Treatment of Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking by LIU Huiling, TAN Dingying, HUANG Min, CHEN Pingping, ZHANG Wang

“…In addition, molecular docking was conducted between the core targets and the active ingredients of <italic>Coptis chinensis</italic> to verify the binding ability between the active ingredients and the core targets.Results① A total of 14 active ingredients of <italic>Coptis chinensis</italic>, 189 targets for the treatment of type 2 diabetes mellitus were screened out, among which 136 potential targets were identified, including 20 core targets (degree≥12), 137 signaling pathways with significant significance. ② Gene Ontology (GO) functional enrichment analysis showed that, the biological processes (BP) involved in the predicted target of <italic>Coptis chinensis</italic> in the treatment of type 2 diabetes mellitus involved gland development, epithelial cell proliferation, regulation of DNA-binding transcription factor activity, oxidative stress and apoptosis response to lipopolysaccharide, etc. …”
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Forecasting stroke and stroke-driven dementia in a rapidly ageing population: a model-based analysis of alternative projection scenarios for Ireland by Anne Hickey, Eithne Sexton, Frances Horgan, Kathleen E Bennett, Ronan Collins, Martin O'Flaherty, Suzanne Timmons, Chris Macey, David J. Williams

“…We also examined nonlinear trends involving decelerating decline over time and varying trends by age.Setting/participants The study is conducted on the Irish population aged 40–89 years in the period 2022–2046. …”
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The combined evaluation of preoperative serum CEA and postoperative tissue CEA as a prognostic factor in stages 0–IV colorectal cancer: a retrospective cohort study by Guojun Tong, Guojun Tong, Hui Li, Yan Shen, Zhenhua Tan, Hai Qian

“…Univariate and multivariate analyses were conducted using Cox regression. All data were analysed using SPSS 27 and R 4.3.1.ResultsSome clinicopathologic features differed significantly among the combined CEA test groups (all p &lt; 0.05). …”
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Association between early dietary patterns and cardiometabolic health at age 8: a confirmatory analysis of the European Childhood Obesity Project by Mariona Gispert-Llauradó, Joaquin Escribano, Natalia Ferré, Veit Grote, Berthold Koletzko, Gina Ambrosini, Elvira Verduci, Dariusz Gruszfeld, Annick Xhonneux, Veronica Luque

“…A cross-sectional and prospective analysis was conducted to evaluate the associations between these DPs and cardiometabolic outcomes, including body mass index (BMI), blood pressure (BP), and biochemical markers. …”
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Human Factors Studies to Assess the Usability of the Faricimab Prefilled Syringe by Barakat MR, Kwong Jr HM, Marcon G, O'Leary OE, Paris LP, Schneider P, Tang Y, Graff JM

“…Here, we report the usability of a novel faricimab 6 mg pre-filled syringe (PFS) configuration that has been designed specifically for intravitreal use.Patients and Methods: A simulated-use human factors validation study enrolling 15 retina specialists and 15 ophthalmic assistants was conducted in a market research facility configured to represent an ophthalmology clinic. …”
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Exploring SLEEPINESS through home monitoring with ultra-long-term subcutaneous EEG and ecological momentary assessment in sleepy treatment naïve obstructive sleep apnea patients st... by Mathias Sarkez-Knudsen, Martin Ballegaard, Martin Ballegaard, Henning Piilgaard, Esben Ahrens, Martin Christian Hemmsen, Tobias Søren Andersen, Jakob Eyvind Bradram, Preben Homøe, Preben Homøe

“…Ethical approval from the Region Zealand Ethics Committee on 13/09/2021 (SJ939, EMN-2021-06803). The study will be conducted in accordance with local legislation and institutional requirements and comply with the Declaration of Helsinki and the General Data Protection Regulation (GDPR).…”
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Comparison between traditional logistic regression and machine learning for predicting mortality in adult sepsis patients by Hongsheng Wu, Biling Liao, Tengfei Ji, Keqiang Ma, Yumei Luo, Shengmin Zhang

“…This study compared the performance of traditional logistic regression and machine learning models in predicting adult sepsis mortality.ObjectiveTo develop an optimum model for predicting the mortality of adult sepsis patients based on comparing traditional logistic regression and machine learning methodology.MethodsRetrospective analysis was conducted on 606 adult sepsis inpatients at our medical center between January 2020 and December 2022, who were randomly divided into training and validation sets in a 7:3 ratio. …”
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Hubungan Pemakaian Fenobarbital Rutin dan Tidak Rutin Pada Anak Kejang Demam dengan Attention Deficit Hyperactivity Disorder (ADHD) by Sara Fadila, Nadjmir ., Rahmatini .

“…This study is based on interviews conducted with questionnaires SPPAHI and processed with statistical chi-square test with a confidence level of 95%.The results showed (1)Children of febrile seizures residing in the city of Padang who taking phenobarbital in Dr. …”
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Apoptosis induction and tumor growth suppression by hydroxyapatite nanoparticles–cisplatin combined treatment in Ehrlich solid carcinoma-bearing mice by Shaymaa M. Eissa, Asmaa M. Mahfouz, Saad M. El-Gendy, Al-shimaa Zakaria, Heba Effat, Hanan R. H. Mohamed

“…ESC group was administrated distilled water, the HAP-NPs group was treated orally with 100 mg/kg of hydroxyapatite nanoparticles, the CDDP group was administrated intraperitoneally with 5 mg/kg of Cisplatin, the HAP-NPs + CDDP group was treated with both doses of hydroxyapatite and cisplatin, the animal treatment was conducted for 20 days. Antitumor activity was assessed for two durations after 10 and 20 days. …”
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Socio-economic inequalities in access to COVID-19 tests in France in 2020: evidence from the EPICOV socio-epidemiological cohort by Pierre-Yves Geoffard, Pierre-Yves Geoffard, Florence Jusot, Antoine Sireyjol, Josiane Warszawski, Nathalie Bajos

“…Our main objective was to investigate whether access to COVID-19 testing in France was associated with socio-economic conditions, considering gender and ethno-racial status.MethodsA random population-based cohort survey was conducted in France in May 2020 and November 2020, including 95,388 participants aged 18 and over. …”
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Is longer really better? Results of a retrospective real-life cohort study evaluating the benefit of adding a weekly educational session to a traditional 8-week home-based pulmonar... by Cécile Chenivesse, Olivier Le Rouzic, Jean-Marie Grosbois, Sarah Gephine, Sophie Peres

“…Primary hypothesis was that 8 home-based supervised sessions will be equivalent to 16 home-based supervised sessions at both short- and long-term after PR.Design Retrospective cohort study conducted on prospectively collected real-life data, from January 2010 to December 2021.Setting FormAction Santé, Pérenchies France.Participants Eligible individuals were aged &gt;18 years with a diagnosis of COPD and referred to the home-based PR programme by their respiratory physician. …”
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