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38561
Safety and efficacy of dual versus triple antithrombotic therapy (DAT vs TAT) in patients with atrial fibrillation following a PCI: a systematic review and network meta-analysis
Published 2020-09-01“…We aimed to compare the efficacy and safety of DAT regimens using a network meta-analysis (NMA) approach.Design A systematic review and NMA of randomised clinical trials.Methods We conducted a systematic literature review to identify relevant randomised clinical trials and performed a Bayesian NMA for International Society on Thrombosis and Haemostasis (ISTH) major or clinically relevant non-major (CRNM) bleeding, all-cause mortality, stroke, myocardial infarction (MI) and stent thrombosis outcomes. …”
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38562
AI-assisted detection for chest X-rays (AID-CXR): a multi-reader multi-case study protocol
Published 2024-12-01“…There is a paucity of evidence on the impact of AI algorithms in assisting healthcare professionals (other than radiologists) who regularly review CXR images in their daily practice.Aims To assess the utility of an AI-based CXR interpretation tool in assisting the diagnostic accuracy, speed and confidence of a varied group of healthcare professionals.Methods and analysis The study will be conducted using 500 retrospectively collected inpatient and emergency department CXRs from two UK hospital trusts. …”
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38563
Efficacy and safety of anemoside B4 in canine pneumonia treatment: a prospective, randomized controlled trial
Published 2025-02-01“…Therefore, AB4 may offer a valuable alternative treatment option for canine pneumonia in veterinary medicine.MethodsA prospective, randomized controlled trial was conducted at the Veterinary Drug Research and Evaluation Center of South China Agricultural University. …”
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38564
Transfer of Cytoplasmic Male Sterility to the Female Parents of Heat- and Drought-Resilient Maize (<i>Zea mays</i> L.) Hybrids
Published 2025-01-01“…In this direction, the research was conducted to transfer cytoplasmic male sterility (CMS-C) from a CMS donor (VL192114) into the female parents (CAL1514 and ZL153493) of heat- and drought-resilient maize hybrids (RCRMH-2 and RCRMH-3) by a marker-assisted backcross scheme. …”
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38565
Impact of Granulocyte Colony-Stimulating Factor (G-CSF) on Clinical Outcomes in Allogeneic Hematopoietic Cell Transplantation: Does Speeding Up Neutrophil Engraftment Make a Differ...
Published 2025-02-01“…In this retrospective cohort study conducted at the Princess Margaret Cancer Centre, we analyzed the clinical outcomes of 509 patients who underwent allogeneic HCT between May 1, 2019, and May 31, 2022. …”
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38566
Machine learning-based identification and validation of amino acid metabolism related genes as novel biomarkers in chronic kidney disease
Published 2025-01-01“…Also, we mapped the ROC curves.Meanwhile, in order to determine the underlying mechanism and relevant biological features of CKD, we conducted differential analysis between high and low risk subgroups in CKD. …”
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38567
Sources and Health Risks of PM2.5-bound PAHs in a Small City along with the “Clean Heating” Policy
Published 2022-06-01“…A field observation was conducted in Baoding City, a small city within the BTH region, in winter of 2019 covering both the pre-heating season (PHS) and the heating season (HS). …”
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38568
The Impact of Hangeshashinto on Symptoms and Gut Microbiota in Diarrhea-type Irritable Bowel Syndrome: A Retrospective Analysis
Published 2025-01-01“…Methods: This was a multicenter retrospective study with a prospective analysis of microbiota conducted at five affiliated institutions. Patients diagnosed with IBS-D based on the ROME IV criteria between April 2019 and December 2023, who received HST 7.5 g/day for 2-3 weeks were included. …”
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38569
Association of HIV infection and hospitalization among mpox cases: a systematic review and meta-analysis
Published 2025-01-01“…Methods A literature search was conducted through PubMed, Embase, Web of Science, Scopus, and the Cochrane Library up until August 10, 2024. …”
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38570
Effect of intravenous urokinase vs best medicine treatment on functional outcome for patients with acute minor stroke (TRUST): a randomized controlled trial
Published 2025-01-01“…Methods This multicenter, open-label, blinded-endpoint, randomized controlled clinical trial enrolled patients with minor stroke within 6 h of symptom onset, with a NIHSS score ≤ 5. The trial was conducted at 25 hospitals in China between October 2020 and February 2023. …”
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38571
Spatial and temporal epidemiology of SARS-CoV-2 virus lineages in Teesside, UK, in 2020: effects of socio-economic deprivation, weather, and lockdown on lineage dynamics
Published 2024-09-01“…As the outbreak continued, new variants were detected through two national monitoring programmes that conducted genomic sequencing. This study aimed to determine the effects of weather, demographic features, and national and local COVID-19 restrictions on positive PCR tests at a sub-regional scale. …”
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38572
Aqueous extracts of Moringa oleifera and Cinnamomum cassia as promising sources of antibiofilm compounds against mucoid and small colony variants of Pseudomonas aeruginosa and Stap...
Published 2025-06-01“…Recognizing that the antibiofilm properties of moringin, a common compound in both moringa seed and cinnamon bark extracts, remain underexplored, we conducted potential target identification via PharmMapper and molecular docking analyses to provide a foundation for future research. …”
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38573
Molecular cloning and expression dynamics of Atrogin-1 in muscle tissue of Russian sturgeon (Acipenser gueldenstaedtii) under high salt stress
Published 2025-03-01“…To elucidate the regulatory mechanism of Atrogin-1 in response to high salt stress in Russian sturgeon, we conducted cDNA cloning and expression analysis. The cDNA encoding the Russian sturgeon protein Atrogin-1 was successfully cloned, comprising 1472 bp and encoding 353 amino acid residues (with an open reading frame of 1062 bp). …”
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38574
Long-term exposure to PM2.5 and its constituents and visual impairment in schoolchildren: A population-based survey in Guangdong province, China
Published 2025-01-01“…Objectives: To explore the effects of long-term exposure to PM2.5 and its constituents on visual impairment. Methods: We conducted a large cross-sectional population-based study to recruit 59,054 schoolchildren from four cities in Guangdong province, China, and used the ChinaHighAirPollutants (CHAP) dataset to estimate 3-year average concentrations of PM2.5 and its constituents (black carbon (BC), organic matter (OM), nitrate (NO3–), sulfate (SO42−) and ammonium (NH4+)) based on individuals’ home addresses. …”
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38575
Beef cattle performance and hair cortisol accumulation in silvopastoral and pastoral systems: a 2-year assessment
Published 2025-03-01“…Silvopastoral practices, such as integrating trees into pastureland or grazing in woodland areas, are potential mitigation strategies to improve microclimate conditions and reduce heat stress risks. We conducted a 2-year on-farm experiment to compare growth performance, measuring average daily gain (ADG), hair cortisol accumulation, and blood glucose concentration in Maremmana breed steers and heifers reared in either a silvopastoral (SP) or pastoral (PA) system during spring and summer. …”
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38576
Management of CAR-T cell therapy in patients with multiple myeloma: a systematic review and expert consensus in Australia
Published 2025-01-01“…To support the introduction of these therapies, we aimed to establish consensus expert opinion on best practices of all aspects of the management of patients with MM undergoing CAR-T cell therapy in Australia.MethodsWe conducted a modified RAND/UCLA two-round Delphi panel informed by a systematic literature review (SLR). …”
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38577
Barriers and facilitators to implementation of a home-based cardiac rehabilitation programme for patients with heart failure in the NHS: a mixed-methods study
Published 2022-07-01“…In 2020, 5 online REACH-HF training events were attended by 85 healthcare professionals from 45 National Health Service (NHS) teams across the UK and Ireland.Design Our mixed-methods study used in-depth semi-structured interviews and an online survey. Interviews were conducted with staff trained specifically for the Beacon Site project, identified by opportunity and snowball sampling. …”
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38578
Ethiopia hygiene practice during complementary feeding and associated factors; systematic review and meta-analysis
Published 2025-01-01“…The meta-analysis was conducted using STATA 17 software to compute pooled prevalence and odds ratios (OR) for the determinant factors, with a 95% confidence interval (CI). …”
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38579
Disparities in anxiety and related factors among Chinese older adults across different aged-care models: a comparison of two cross-sectional studies
Published 2025-01-01“…However, fewer studies have been conducted on differences in anxiety among older individuals in different aged-care models, and the interactive relationship between the influencing factors on anxiety remains unclear. …”
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38580
Characteristics and contributing factors of adverse drug reactions: an analytical study of patients with tuberculosis receiving treatment under the National TB Program of India [ve...
Published 2024-07-01“…Methods An observational cross-sectional study was conducted in selected districts of Gujarat state. A total of 593 reported TB patients were recruited with an adjusted unified distribution based on the type of cases, site of diseases, and service facility through a simple random sampling method. …”
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