Gut microbiota, metabolites, and cytokines in relation to the risk of prostate cancer in the Asian population by Zhengshi Wang, Zhengshi Wang, Zhengshi Wang, Zhengshi Wang, Zhengshi Wang, Haotian Chen, Haotian Chen, Yongqiang Liu, Yongqiang Liu, Libin Zou, Libin Zou, Zhijin Zhang, Zhijin Zhang, Zhiqiang Yin, Zhiqiang Yin, Shiyu Mao, Shiyu Mao, Changcheng Guo, Changcheng Guo, Bin Yang, Bin Yang, Pengfei Wu, Pengfei Wu, Pengfei Wu, Xudong Yao, Xudong Yao

“…Sensitivity analyses were conducted to test the reliability of MR results. Furthermore, the FinnGen database was used to assess the generalizability of our findings based on Asians.ResultsThere were a total of 17 bacterial traits, 28 metabolites (including 2 microbiota-associated metabolites), and 9 cytokines to be significantly associated with prostate cancer in Asians (P < 0.05). …”
Get full text

Changes on the Development of Rigor Mortis in Cultured Tilapia (Oreochromis niloticus) Fed with a Mixture of Plant Proteins by Nathaly Montoya Camacho, Enrique Márquez Ríos, Francisco Javier Castillo Yáñez, Saúl Ruíz Cruz, Aldo Alejandro Arvizu Flores, Wilfrido Torres Arreola, Jose Luis Cárdenas López, Santiago Valdéz Hurtado, Víctor Manuel Ocaño Higuera

“…The fish were divided into triplicate groups per dietary treatment. The experiment was conducted in a tank system at 26.8°C water temperature for 67 days. …”
Get full text

Long-term effects of dupilumab on chronic rhinosinusitis with nasal polyps: A step towards clinical remission by Mona Al-Ahmad, MD, FRCPC, Asmaa Ali, MD, PhD, Wafaa Talat, MD, PhD, Haitham A. Dawood, MD, PhD, Osama Imam, MD, PhD

“…Methods: A two-year prospective study was conducted on 109 patients with CRSwNP, with or without asthma, who were eligible for dupilumab as an add-on therapy. …”
Get full text

Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developin... by Akihiko Kawahara, Tetsuro Sasada, Koichi Azuma, Hidenobu Ishii, Norikazu Matsuo, Takaaki Tokito, Tomoaki Hoshino, Yohei Miyagi, Huihui Xiang, Tomoyuki Tagami, Rika Kasajima, Yumiko Kato, Sachise Karakawa, Shinya Kikuchi, Akira Imaizumi, Kenta Murotani

“…However, the clinical significance of free amino acids (plasma-free amino acids (PFAAs)) and tryptophan-related metabolites in plasma has not been fully understood in patients with non-small cell lung cancer (NSCLC) who receive immune checkpoint inhibitors.Methods We conducted a single cohort observational study. Peripheral blood samples were collected from 53 patients with NSCLC before treatment with PD-1 (Programmed cell death-1) inhibitors. …”
Get full text

Clinical utility and predictive value of cerebrospinal fluid cell-free DNA profiling in non-small cell lung cancer patients with leptomeningeal metastasis by Sheng-Kai Liang, Wei-Yu Liao, Jin-Yuan Shih, Chia-Lin Hsu, Ching-Yao Yang, Shang-Gin Wu, Yen-Ting Lin, Yueh-Feng Wen, Lun-Che Chen, Yen-Fu Chen, Ya-Fang Chen, Yen-Heng Lin, Chong-Jen Yu

“…Cerebrospinal fluid (CSF) cell-free DNA (cfDNA) analysis using next-generation sequencing (NGS) offers insights into resistance mechanisms and potential treatment strategies. We conducted a study from February 2022 to April 2023 involving patients from five hospitals in Taiwan who had recurrent or advanced NSCLC with LM. …”
Get full text

Predicting breast cancer prognosis using PR and PIK3CA biomarkers: a comparative analysis of diagnostic groups by Yuting Feng, Qingzhen Song, Lei Yan, Ruoqi Li, Mengqin Yang, Peng Bu, Jing Lian

“…Methods A retrospective analysis was conducted on 152 HR+/HER2 − breast cancer patients stratified by PR expression levels and PIK3CA mutation status. …”
Get full text

Efficacy of personalized feedback in encouraging sustainable washing behavior: evidence from a pilot study in Germany by Laura Höpfl, Laura Höpfl, Laura Höpfl, Ivan Đula, Ivan Đula, Ivan Đula, Francisco Kiss, Rebecca Walter, Maria Wirzberger, Maria Wirzberger, Maria Wirzberger

“…Asynchronous structured interviews were conducted at the end to explore participants' perceptions and washing behaviors.ResultsWhile we found effects for the feedback manipulation, we found no differences between user clusters in individual washing behaviors. …”
Get full text

Larvicidal activity of Bacillus thuringiensis strains against Aedes aegypti and Culex quinquefasciatus mosquitoes by Prakai Rajchanuwong, Sawaporn Peaboon, Ratchadawan Ngoen-Klan, Atsalek Rattanawannee, Atirat Noosidum, Boonhiang Promdonkoy, Jariya Chanpaisaeng, Theeraphap Chareonviriyaphap

“…Preliminary bioassays conducted on 434 strains demonstrated that 41 strains (11.64%) and 14 strains (3.97%) achieved 100% mortality against Ae. aegypti and Cx. quinquefasciatus larvae, respectively. …”
Get full text

The effects of the urotensin-II receptor antagonist palosuran treatment on the corpora cavernosa of streptozotocin-induced diabetic rats by Murat Olukman, Cenk Can, Sibel Ülker, Yiğit Uyanikgil, Türker Çavuşoğlu, Neslihan Düzenli, Deniz Coşkunsever, Fatma G. Kozcu

“…Conclusion: Palosuran treatment did not affect the expression of NOSs or reduce nitrergic conduction induced by EFS stimulation in diabetic CC. …”
Get full text

EGR1 mRNA expression levels and polymorphisms are associated with slaughter performance in chickens by Mao Ye, Xiaohuan Chao, Chutian Ye, Lijin Guo, Zhexia Fan, Xuerong Ma, Aijun Liu, Weiming Liang, Shuya Chen, Cheng Fang, Xiquan Zhang, Qingbin Luo

“…In our previous study, we conducted transcriptome sequencing on chicken breast tissues with high and low breast muscle rates and found higher early growth response protein 1 (EGR1) expression in breast tissues with a low breast muscle ratio, thus hypothesizing that the EGR1 gene is involved in the growth and development process of chicken muscle tissues. …”
Get full text

Sex and race disparities in emergency department patients with chest pain and a detectable or mildly elevated troponin by Lucas M. Boyer, Anna C. Snavely, Jason P. Stopyra, Subha V. Raman, Jeffrey M. Caterino, Carol L. Clark, Alan E. Jones, Michael E. Hall, Carolyn J. Park, Brian C. Hiestand, Sujethra Vasu, Michael A. Kutcher, W. Gregory Hundley, Simon A. Mahler, Chadwick D. Miller

“…The goal of this analysis is to determine whether cardiac testing or outcome disparities exist by race or sex in patients with detectable to mildly elevated serum troponin. Methods: We conducted a secondary analysis of the CMR-IMPACT trial that randomized patients with symptoms suggestive of acute coronary syndrome and a detectable or mildly elevated troponin measure from 4 US hospitals to an early invasive angiography or cardiac MRI strategy. …”
Get full text

Correlations among fatigue, respiratory function, balance and core muscle morphology in multiple sclerosis: a comprehensive observational study by Marta De La Plaza San Frutos, Ismael Sanz-Esteban, Ismael Sanz-Esteban, Federico Salniccia, Federico Salniccia, Alberto Bermejo-Franco, Alberto Bermejo-Franco, Ameyalli García-Corona, María Cristina Palma-Baquedano, Marina Castel-Sánchez, Marina Castel-Sánchez, Cecilia Estrada-Barranco, Cecilia Estrada-Barranco

“…This study examines the relationship between fatigue, respiratory function, balance, and ultrasound variables of abdominal musculature in MS.MethodsA cross-sectional study was conducted involving 27 subjects diagnosed with MS, comprising 17 females and 10 males. …”
Get full text

Economic impact of heart failure with preserved ejection fraction: insights from the ALDO‐DHF trial by Djawid Hashemi, Ludwig Dettmann, Tobias D. Trippel, Volker Holzendorf, Johannes Petutschnigg, Rolf Wachter, Gerd Hasenfuß, Burkert Pieske, Antonia Zapf, Frank Edelmann

“…Methods and results The aldosterone receptor blockade in diastolic HF trial is a multicentre, prospective, randomized, double‐blind, placebo‐controlled trial conducted between March 2007 and April 2011 at 10 sites in Germany and Austria that included 422 ambulatory patients [mean age: 67 years (standard deviation: 8); 52% women]. …”
Get full text

The association of RBP4 with chronic kidney diseases in southern Chinese population by Tong Chen, Tong Chen, Tong Chen, Yu Liu, Yu Liu, Shiquan Wu, Siyu Long, Ling Feng, Wenqian Lu, Wenya Chen, Guoai Hong, Li Zhou, Fang Wang, Yuechan Luo, Hequn Zou, Hequn Zou, Weihua Liu

“…This study was designed to clarify the relationship between RBP4 and CKD and its potential predictive value.MethodsOur team has conducted a large-scale cross-sectional survey that contained 2117 individuals on the southern coast of China. …”
Get full text

Deep Transfer Learning for Classification of Late Gadolinium Enhancement Cardiac MRI Images into Myocardial Infarction, Myocarditis, and Healthy Classes: Comparison with Subjective... by Amani Ben Khalifa, Manel Mili, Mezri Maatouk, Asma Ben Abdallah, Mabrouk Abdellali, Sofiene Gaied, Azza Ben Ali, Yassir Lahouel, Mohamed Hedi Bedoui, Ahmed Zrig

“…The performance of the VGG16-MLP model was compared with a subjective visual analysis conducted by two blinded independent readers. <b>Results:</b> The VGG16-MLP model allowed high-performance differentiation between MI, myocarditis, and healthy LGE cardiac MRI images. …”
Get full text

Desire for labor companionship and its associated factors among pregnant women attending antenatal care at public health facilities in Debre Berhan City: a cross-sectional study by Mulualem Silesh, Tesfanesh Lemma Demisse, Kidist Ayalew Abebe, Birhan Tsegaw Taye, Tebabere Moltot, Moges Sisay Chekole, Fetene Kasahun, Abebayehu Melesew Mekuriyaw, Tirusew Nigussie Kebede, Kibret Hailemeskel

“…Due to the limited studies on women's preferences for labour companionship, this study aimed to assess the desire for labour companionship and its associated factors among pregnant women attending ante-natal care at public health facilities in Debre Berhan City.MethodA facility-based cross-sectional study was conducted from August 1–30, 2022. A face-to-face questionnaire administered was used to collect data. …”
Get full text

Plasma IL-17A is increased in patients with critical MIS-C and associated to in-hospital mortality by Emmerson C. F. de Farias, Luciana M. P. P. do Nascimento, Manoel J. C. Pavão Junior, Dalila C. A. Pavão, Ana P. S. Pinheiro, Andreza H. O. Pinheiro, Marília C. B. Alves, Kíssila M. M. M. Ferraro, Larisse F. Q. Aires, Luana G. Dias, Mayara M. M. Machado, Michaelle J. D. Serrão, Raphaella R. Gomes, Sara M. P. de Moraes, Gabriela C. L. Pontes, Railana D. F. P. Carvalho, Cristiane T. C. Silva, Carla M. A. das Neves, Joyce C. L. dos Santos, Adriana M. B. de Sousa, Leda L. da Silva, Mary L. F. M. F. de Mello, Patricia B. Carvalho, Renata de B. Braga, Kathia de O. Harada, Maria C. A. Justino, Iran B. Costa, Igor Brasil-Costa, Marta C. Monteiro, Gleice Clemente, Maria Teresa Terreri

“…Univariate and multivariate Cox regression analyses were conducted. The ROC (Receiver Operating Characteristic) curve analysis was performed.Results and conclusionsA total of 41 patients out of 109 patients admitted at PICU with suspected MIS-C during the study period were included, of which 33 (80.5%) were male, 9 (22%) were under one year old, and 30 (73.2%) presented comorbidities. …”
Get full text

Cross-cultural adaptation and psychometric evaluation of the Thai version of the Enhancing Recovery in Coronary Heart Disease Social Support Inventory in individuals with chronic i... by Santi Phetrnui, Jom Suwanno, Chantira Chiaranai, Chonchanok Bunsuk, Naruebeth Koson, Wanna Kumanjan, Chennet Phonphet, Ladda Thiamwong

“…Methods: A scale translation and cross-sectional validation study was conducted. The English version was translated for Thai involved nine steps: preparation, forward translation, reconciliation, back-translation, back-translation review, harmonization, cognitive debriefing, review of cognitive debriefing and finalization, and proofreading. …”
Get full text

Nitrogen fertilizer application for improving the biomass, quality, and nitrogen fixation of alfalfa (Medicago sativa L.) at different growth stages in a saline‒alkali soil by Weifan Wan, Qian Liu, Ke Li, Kun Zhao, Fei Qi, Yuanshuo Li, Zhi Sun, Haigang Li

“…A 2-year (2020 and 2021) field experiment with five N fertilizer application rates, namely, 0 (N0), 20 (N20), 60 (N60), 120 (N120) and 180 (N180) kg N ha−1, was conducted in Inner Mongolia. Results The results showed that N fertilizer application of 180 kg ha−1 significantly increased the total alfalfa yield by 29%–32% by improving the stem‒leaf ratio; however, it didn’t lead to a further increase in alfalfa quality. …”
Get full text

Have the COVID-19 pandemic and lockdown affected children’s mental health in the long term? A repeated cross-sectional study by Alan Johnson, Sayan Mukherjee, Sushant Mane, Manas Pustake, Ajit Bhagwat, Mohammad Arfat Ganiyani, Misba Sayed, Varada Mithbavkar, Zaid Memon, Abdus Samad Momin, Krishna Deshmukh, Ayush Chordia, Sabyasachi Parida, Sanket Warghade, Deepankar Varma

“…Objective The study aimed to evaluate the impact of the COVID-19 pandemic on levels of anxiety and depressive symptoms in children and adolescents.Design Cross-sectional surveys were carried out on the mental health of children; one survey was conducted before the COVID-19 pandemic and one into the pandemic, 15 months after the school closures and implementation of lockdown and social distancing. …”
Get full text