Long non-coding RNA MIR4435-2HG modulates pancreatic cancer stem cells and chemosensitivity to gemcitabine by targeting the miR-1252-5p/STAT1 by Baocheng Xie, Peishan Wu, Hongyu Liu, XiangDi Yang, Linxuan Huang

“…Functional assays were conducted to evaluate CSC self-renewal, tumorigenic potential, and chemoresistance in pancreatic cancer cells with altered expression of MIR4435-2HG. …”
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Biomimetic bioreactor for potentiated uricase replacement therapy in hyperuricemia and gout by Bin Yang, Bin Yang, Guihu Luo, Tailei Nie, Zhenglan Ban, Quanxin Ning, Jialin Zhang, Xiangru Liu, Yanhua Lin, Xiaochun Xie, Qianyun Chen, Han Zhong, Ying Huang, Pan Liao, Yan Liu, Chenyang Guo, Chuanxu Cheng, Erwei Sun, Erwei Sun

“…In vitro assays were conducted to evaluate biocompatibility, anti-inflammatory effects, and oxidative stress protection. …”
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Thermal ablation included in multimodality treatment predicts enhanced survival in advanced non-small cell lung cancer: a propensity score-matched outcome study by Stella Chin-Shaw Tsai, Yi-Min Chen, Yueh-Han Ku, Chia-Hsuan Hsu, Tzu-Hsuan Hsiao, Pin-Hsu Liao, Tzu-Chin Wu, Frank Cheau-Feng Lin

“…This study aimed to evaluate the impact of adding thermal ablation (TA) in treatment regimens for advanced NSCLC to improve survival outcomes.Methods A retrospective cohort study was conducted at a medical center in Taiwan, analyzing data from 1,083 patients diagnosed with stage IIIB or IV NSCLC between 2008 and 2020. …”
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Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin-Induced Cardiotoxicity in Rats by Olufunke Esan Olorundare, Adejuwon Adewale Adeneye, Akinyele Olubiyi Akinsola, Daniel Ayodele Sanni, Mamoru Koketsu, Hasan Mukhtar

“…Preliminary qualitative and quantitative assays of CVE’s secondary metabolites were also conducted. Phytochemical analyses revealed the presence of flavonoids (34.79 ± 0.37 mg/100 mg dry extract), alkaloids (36.73 ± 0.27 mg/100 mg dry extract), reducing sugars (07.78 ± 0.09 mg/100 mg dry extract), and cardiac glycosides (24.55 ± 0.12 mg/100 mg dry extract). 50–400 mg/kg/day CVE significantly attenuated increases in the serum LDH and troponin I levels. …”
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Current trends in e-mental health interventions: Health care providers' attitudes and usage patterns by Elena Caroline Weitzel, Katja Schladitz, Maria Schwenke, Franziska Dinah Welzel, Georg Schomerus, Peter Schönknecht, Markus Bleckwenn, Anja Mehnert-Theuerkauf, Steffi G. Riedel-Heller, Margrit Löbner

“…Methods: Data for this explorative analysis derive from a longitudinal study of N = 335 health care providers from four professional groups in German mental health care (GPs, specialist doctors, psychotherapists, and clinicians). In two surveys conducted one year apart, usage as well as advantages of and barriers to e-mental health interventions were assessed. …”
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Investigating the Agreement of Hypomagnesemia Diagnosis in Three Perimeter of Serum, Urine, and Red Blood Cell in Intensive Care Unit: Pilot Study by Nastaran Nazarzade, Mojtaba Mojtahedzadeh, Farshid Gholami, Amirmahdi Mojtahedzadeh, Maryam Shiehmorteza, Amirhossein Ghanbarzamani

“…Methods: Diagnosis of hypomagnesemia is done by measuring serum magnesium, urine magnesium, and magnesium in RBCs. We conducted a prospective study on 30 critically ill patients (14 male, and 16 female) who were admitted to the ICU to examine the prevalence of magnesium deficiency. …”
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Phytochemical Screening and Cytotoxic Properties of Ethanolic Extract of Young and Mature Khat Leaves by Rashad Alsanosy, Hassan A. Alhazmi, Shahnaz Sultana, Ashraf N. Abdalla, Yassin Ibrahim, Mohammed Al Bratty, David Banji, Ibrahim Khardali, Asaad Khalid

“…Cytotoxicity investigations were also conducted on both types of leaves using three cancer cell lines, human breast adenocarcinoma, human ovary adenocarcinoma, and human colon adenocarcinoma and also normal human fetal lung fibroblast cell line was used. …”
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Increased indexed proximal aortic diameter is a predictor of poor prognosis in maintenance hemodialysis patients by Junwei Xu, Wenyi Tang, Lizheng Song, Yuxi Huang, Li Xiao, Fangyuan Cheng, Qianglin Guan, Mei Xu, Chuoxin Ma, Jian Chen, Jianting Ke

“…Cox proportional hazards models were conducted to evaluate the association between baseline ARD/BSA and clinical outcomes.Results A total of 391 patients were included in this study. …”
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Effect of preoperative hair removal vs. no removal on surgical site infections: a systematic review and meta-analysis [version 1; peer review: 2 approved] by Abdulsalam Aleid, Zainab Aleid, Abdulmajeed Aljabr, Abdulrahman Almoslem, Lama AlOraini, Mutlaq Alsubaie, Abdulaziz Alharthi, Hasan Ali Abdullah Alaidarous, Saud Nayef Aldanyowi, Abbas Al Mutair

“…Methods A systematic review and meta-analysis were conducted according to PRISMA guidelines. Three databases—PubMed, Web of Science, and Cochrane Library—were searched for relevant studies comparing preoperative hair removal to no hair removal. …”
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PDIA3 rs2788: An Independent Risk Factor for Hypertension and Its Interaction With Antihypertensive Medications by Hongtao Lan, Yingbin Xi, Baoxu Kang, Zhoujie Tong, Jie Peng, Wei Zhang, Ming Zhong, Huiping Gong, Zhihao Wang

“…Finally, stratified analyses were conducted to further assess interactions between PDIA3 rs2788 and antihypertensive medications. …”
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Formation Pathways and Emission Characteristics of PCDD/Fs during Co-combustion Tests of Sewage Sludge in Coal-fired Power Plants by Xiangbo Zou, Ji Ye, Chuangting Chen, Hui Huang, Wenxin Yu, Yuxuan Ying, Tieying Mao, Yunfeng Ma, Bingjian Zhu, Xiaoqing Lin

“…Abstract This study was conducted in a full-scale coal-fired power plant (350 MW), mainly investigating the co-combustion influence of sewage sludge (SS) on the formation and emission characteristics of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs). …”
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Unsteady ground: understanding the problem of BPPV in the world of sports by Wojciech Nowak, Mirosław Sawicki, Jagoda Mikołajczyk, Paulina Krzemińska, Maciej Gołębski, Zuzanna Kukla, Sebastian Musialik, Stella Mieruszyńska, Jakub Włosiański, Izabela Sadowska

“…Material and methods: This article is based on a comprehensive review of the literature, conducted using PubMed and Google Scholar. The research focused on studies concerning the prevalence, etiology and risk factors of BPPV, particularly in sports practitioners. …”
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Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer by Abhishek Chauhan, Hemant Joshi, Divya Kandari, Diwakar Aggarwal, Ritu Chauhan, Hardeep Singh Tuli, Arpit Mehrotra, Abhilasha Sood, Ujjawal Sharma, Darin Mansor Mathkor, Shafiul Haque, Naveen Chandra Joshi, Laurent Dufossé

“…Methods: A systematic literature search was conducted using Scopus, PubMed, SpringerLink, ScienceDirect, Wiley Online, and Web of Science databases, covering the period from 2007 to 2024. …”
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Adverse events in the nervous system associated with blinatumomab: a real-world study by Wen Gao, Jingwei Yu, Yifei Sun, Zheng Song, Xia Liu, Xue Han, Lanfan Li, Lihua Qiu, Shiyong Zhou, Zhengzi Qian, Xianhuo Wang, Huilai Zhang

“…Thorough medication evaluation should be conducted before administering blinatumomab, especially for high-risk patients with preexisting neurological conditions.…”
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Safety and efficacy of intraoperative radiation therapy using a low-energy X-ray source for resectable pancreatic cancer: an interim evaluation of an ongoing prospective phase II s... by Xingyun Chen, Shuo Li, Chuntao Gao, Wei Wang, Haorui Li, Yuxiao Liu, Rui Liu, Jihui Hao

“…Therefore, this study was conducted to evaluate the safety and efficacy of IORT using a 50 kV X-ray source in treating RPC. …”
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Experimental Study on Impermeability Law of Aquiclude Reconstructed by Mudstone of External Dump in Arid Zone by Li Ma, Chendong Liu, Yinli Bi, Suping Peng, Kaisheng Jiang, Hui Zhang, Qiang Luo, Fei Xue, Tianxin Xu, Tianxiang Li, Jing Wu, Jiahao Tian, Dongxu Zhang

“…And the particle size of 0.5 mm, 1 mm, and 2 mm and the thickness of 5 cm, 10 cm, and 20 cm rock samples were selected to conduct the indoor soil column experiment. Three indicators of initial infiltration rate, stable infiltration rate, and average infiltration rate were obtained according to the analysis and calculation of the water column drop rate, wet peak drop rate, and cumulative infiltration rate so that the permeability law and coefficient of each group of tests can be known. …”
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Primary small cell carcinoma of the esophagus: Comparison between a Chinese cohort and Surveillance, Epidemiology, and End Results (SEER) data by Qin Xiao, Haifan Xiao, Shuyu Ouyang, Jinming Tang, Baihua Zhang, Hui Wang

“…Abstract Background The optimal standard treatment for primary small cell carcinoma of the esophagus (SCCE) remains undetermined. In this study, we conducted two areas of research on SCCE. First, we analyzed differences in SCCE characteristics between Chinese and U.S. patients. …”
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Xen 63 versus Preserflo MicroShunt implant in patients with primary open-angle glaucoma by José María Martínez-de-la-Casa, Antonio Pascual-Santiago, Laura Morales-Fernandez, Federico Saez-Frances, Sofia Garcia-Saenz, Noemi Guemes-Villahoz, Ruben Sanchez-Jean, Carmen Mendez, Julian Garcia-Feijoo

“…It is a retrospective and single-center study conducted on consecutive on patients with medically uncontrolled POAG who underwent either a standalone Xen 63 or a standalone Preserflo and had a 12-month follow-up visit. …”
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OMERACT GCA phantom project: validation of a 3D-printed ultrasound training phantom for diagnosis of giant cell arteritis by Annamaria Iagnocco, Christian Dejaco, Richard J Wakefield, Stavros Chrysidis, Sara Monti, Thomas Daikeler, Esperanza Naredo, Lene Terslev, Wolfgang A Schmidt, Alojzija Hočevar, Christina Duftner, Chetan Mukhtyar, Valentin Sebastian Schäfer, Kate Smith, Eugenio De Miguel, Marcin Milchert, Andreas P Diamantopoulos, Pierluigi Macchioni, Uffe Møller Døhn, George A Bruyn, Verena Tischler, Wolfgang Hartung, Markus Aschwanden, Giuseppe Germanò, Aaron Juche, Rositsa Karalilova, Dennis Boumans, Kresten Krarup Keller, Luca Seitz, Berit Nielsen, Tobias Schremmer, Florian Recker, Cees Haagsma, Pantelis Karakostas, Borsha Sarker

“…Due to difficulties with the delineation of the intima-media complex, the parietal branch of the phantoms was modified, and a second round was conducted. The IMT was measured, and phantoms were classified as normal or vasculitic.Results In both rounds, the phantoms were correctly classified as normal/abnormal in >81% of cases yielding a Fleiss’ kappa of 0.80 (95% CI 0.78 to 0.81) in round 1 and 0.74 (95% CI 0.72 to 0.75) in round 2. …”
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Haemodynamic changes of interatrial shunting devices for heart failure: a systematic review and meta‐analysis by Tieci Yi, Min Li, Fangfang Fan, Lin Qiu, Zhi Wang, Haoyu Weng, Xiaoke Shang, Changdong Zhang, Wei Ma, Yan Zhang, Yong Huo

“…Abstract Aims To assess the efficacy and safety, primarily in relation to the haemodynamic effects, of interatrial shunting devices (ISD) for the treatment of heart failure (HF), we conducted a systematic review and a meta‐analysis. …”
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