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34841
Effects of community family doctors-led intervention for self-management and medication adherence in type 2 diabetes mellitus patients: study protocol of a cluster randomised contr...
Published 2022-07-01“…This protocol describes a planned randomised controlled trial to evaluate the effectiveness of a family doctor-led intervention model for diabetes self-management and medication adherence in type 2 diabetes mellitus patients.Methods and analysis This is a Standard Protocol Items: Recommendations for Interventional Trials-compliant cluster randomised controlled trial. The study will be conducted at four CHCs (community health centers). …”
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34842
Did the resurgence of childhood lower respiratory infections offset the initial benefit of COVID-19-related non-pharmaceutical interventions in children? A time-series analysis
Published 2025-02-01“…Whether this recent upsurge overwhelms the initial benefit of NPI remains unknown. Methods We conducted an interrupted time-series analysis based on exhaustive national surveillance systems. …”
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34843
Enhanced sulfate formation in mixed biomass burning and sea-salt interactions mediated by photosensitization: effects of chloride, nitrogen-containing compounds, and atmospheric ag...
Published 2025-01-01“…However, there has been a notable dearth of research conducted on the interactions between sea-salt aerosol and biomass burning plumes, impeding a comprehensive understanding of sulfate formation. …”
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34844
An Educational Web-Based Expert System for Novice Highway Technology in Flexible Pavement Maintenance
Published 2021-01-01“…Experts were interviewed, and a questionnaire survey was conducted to construct the knowledge base of the system. …”
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34845
Involvement of HLADQA1*05 in Patients with Inflammatory Bowel Disease Treated with Anti-TNF Drugs
Published 2025-01-01“…<i>Methods</i>: Sixty-five paediatric IBD patients were enrolled, with therapeutic drug monitoring (TDM) of IFX and ADA, conducted using immunoenzymatic assays. The presence of the HLA-DQA1*05 T>C allele variant was also tested using a Biomole HLA-DQA1 Real-time PCR kit. …”
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34846
Characterization of the Phosphotransferase from <i>Bacillus subtilis</i> 1101 That Is Responsible for the Biotransformation of Zearalenone
Published 2025-01-01“…The product transformed by ZPH1101 was identified as phosphorylated ZEA (ZEA-P) through LC-TOF-MS/MS analysis. The experiments conducted on MCF-7 cells demonstrated that ZEA-P exhibited a lower level of estrogenic toxicity than ZEA. …”
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34847
Screening and identification of host signaling pathways for alleviating influenza-induced production of pro-inflammatory cytokines, IP-10, IL-8, and MCP-1, using a U937 cell-based...
Published 2025-01-01“…This model has been previously validated in our laboratory as an appropriate system for screening anti-inflammatory agents and potential drug targets. We conducted a screening assay employing an inhibitor library consisting of 2,138 compounds that target various known pathways and host factors. …”
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34848
Single-cell sequencing reveals cell heterogeneity and aberrantly activated pathways associated with microvascular invasion in hepatocellular carcinoma
Published 2025-01-01“…This study aims to explore these aspects using single-cell transcriptomic analysis.MethodsThe present study utilized single-cell transcriptomic data from public databases to conduct an in-depth transcriptome analysis of tumour tissues and adjacent nontumor tissues from five patients with hepatocellular carcinoma, with a particular focus on samples from three patients exhibiting microvascular invasion. …”
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34849
Assimilating FY-4B AGRI Three Water Vapor Channels in Operational Shanghai Typhoon Model (SHTM) Using GSI-Based 3-DVar Approach
Published 2025-01-01“…This study conducts a one-month parallel experiment to compare the results of the operational Shanghai Typhoon Model with (WV123) and without (CTL) the assimilation of clear-sky brightness temperature from three Fengyun-4B (FY-4B) Advanced Geostationary Radiation Imager (AGRI) water-vapor (WV) channels. …”
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34850
Polydatin retards the progression of osteoarthritis by maintaining bone metabolicbalance and inhibiting macrophage polarization
Published 2025-01-01“…MicroCT analysis was conducted to assess changes in the microstructure of subchondral bone trabeculae, and Western blot was performed to measure the expression of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway and markers of M1 polarization in macrophages.ResultsPD significantly delays the progression of osteoarthritis induced by ACLT, effectively inhibits IL-1β-induced joint inflammation, bone metabolic remodeling and extracellular matrix degradation. …”
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34851
Nicotine is associated with smoking dependence and vascular inflammation through cotinine: A mediation analysis
Published 2024-01-01“…Methods A cross-sectional study was conducted with 200 participants grouped into two groups based on their smoking status: 100 smokers and 100 non-smokers. …”
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34852
Phenotypic age mediates the associations between platelet-to-lymphocyte ratio and all-cause and cause-specific mortality: A prospective cohort study
Published 2025-01-01“…Mediation analyses were conducted to investigate the mediated effects of PhenoAge on the associations of PLR with mortality. …”
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34853
Different nitrogen uptake patterns of plant and soil microorganisms in the forest-grassland transition zone on the Loess Plateau
Published 2025-01-01“…IntroductionIt is unclear whether plants and microorganisms achieve niche complementarity by taking up different inorganic nitrogen (N) forms to alleviate N competition, particularly in N–limited regions.MethodsThis paper conducted a 15-day 15N tracer study (15NH4NO3 or 15NH4NO3) in situ to quantitatively calculate the uptake rates of plants and microorganisms in four stands (pure Hippophae rhamnoides L, pure Pinus tabuliformis Carrière, mixed H. rhamnoides–P. tabuliformis, and Artemisia gmelinii Weber ex Stechm grassland) in the forest–grassland transition zone on the Loess Plateau during the growing season. …”
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34854
Gut health-promoting foods intake in Argentine adults: The impact of knowledge, socio-demographic factors, and clinical-nutritional health
Published 2025-03-01“…Methods: A cross-sectional study was conducted on 2128 Argentine adults aged 18-82 years-old. …”
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34855
External particle mixing influences hygroscopicity in a sub-urban area
Published 2025-01-01“…During the ACROSS campaign (Atmospheric ChemistRy Of the Suburban foreSt, conducted in Paris in summer 2022), particles' hygroscopic growth rates at 90 % relative humidity (RH) and chemical composition were measured at the sub-urban site using a Hygroscopicity Tandem Differential Mobility Analyser (HTDMA, scanning at 100, 150, 200, and 250 nm) and an Aerodyne High-Resolution Time-of-Flight Aerosol Mass Spectrometer (HR-ToF-AMS). …”
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34856
The impact of the COVID-19 pandemic on HIV testing in Peru: an interrupted time series analysis from 2014 to 2022
Published 2025-01-01“…Methods Utilizing data from the National Demographic and Health Survey of Peru from 2014 to 2022, we conducted an interrupted time series analysis. The proportion of past-year HIV testing per quarter of each year was considered our unit of analysis. …”
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34857
Electrodermal activity and skin temperature characteristics related to stress and depression: A 4-week observational study of office workers
Published 2025-04-01“…Results: Participants with PHQ-9 scores ≥5 showed higher median skin conductance and median tonic signal, although these differences lost statistical significance after Bonferroni correction. …”
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34858
Nutrient Formulation—A Sustainable Approach to Combat PRSV and Enhance Productivity in Papaya
Published 2025-01-01“…To combat PRSV and enhance productivity, a nutrient formulation was developed by combining organic, inorganic nutrient sources with biocontrol agents to improve the health and vigor of the plants. Experiments were conducted to standardize the application time and evaluate the efficacy of nutrient formulation in enhancing yield, and to combat papaya ring spot virus (PRSV) incidence in papaya from January 2021 to December 2023 at Tamil Nadu Agricultural University, Coimbatore, Tamil Nadu, India. …”
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34859
Evaluating the use of Uromune® autovaccine in recurrent urinary tract infections: a pilot unicenter retrospective study in Reus, Spain
Published 2025-01-01“…Methods This pilot retrospective study, conducted at Hospital Universitari de Sant Joan de Reus from January 2018 to August 2022, assessed the association between Uromune® administration and changes in recurrent UTIs. …”
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34860
Recovery trajectories of mental health symptoms among Chinese adolescents following the end of COVID-19
Published 2024-12-01“…This study aims to examine the recovery trajectories of ten mental health problems and suicidal ideation among Chinese adolescents post-pandemic, with a focus on identifying factors that influence different recovery patterns.MethodsA total of 2,534 adolescents participated in a three-wave survey, conducted in June 2022, November 2022, and March 2023, using the Mental Health Scale for Chinese Middle School Students. …”
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