The power of personas: Exploring an innovative model for understanding stakeholder perspectives in an oncology learning health network by Dylan J. Cooper, Jessie Karten, Sarah E. Hoffe, Daniel A. King, Matthew Weiss, Danielle K. DePeralta, Andrew L. Coveler, Sunil R. Hingorani, Tracey Shefter, Cheryl Meguid, Hannah Roberts, Theodore S. Hong, Amol Narang, Amy Hacker‐Prietz, George A. Fisher, Jay Sandler, Laurie Singer, Bobby Korah, William Hoos, Carrie T. Stricker, Joseph M. Herman

“…Methods We partnered with a firm experienced in qualitative research and human‐centered design to conduct interviews with stakeholders of The Canopy Cancer Collective, a newly developed pancreatic cancer LHN. …”
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Interest, uptake, and feasibility trial of a real-life digital health intervention to improve lifestyle in Brazil by Raquel B De Boni, Jurema C Mota, Michael Duncan, Leonardo Linconl, Giovanna Lucieri Alonso Costa, Sofia Pimentel, Kamila P Sales, Fabiana Gaspar, Fernanda Adaes, Felipe B Schuch, Vicent Balanzá-Martinez, Flavio Kapczinski, Renato S Lima

“…Methods A fully online feasibility trial was conducted from April to December 2023. Participants were adults who lived in Rio de Janeiro and reported using the Brazilian Public Health System. …”
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Randomised cross-over trial of vildagliptin and pioglitazone as add-on therapy in patients with type 2 diabetes: predicting Which One is Right Here (WORTH) study protocol by Yannan Jiang, Tony R Merriman, Rui Qian Yeu, Rebecca Brandon, Dale Griffiths, Kate Smallman, Allan Moffitt, Glenn Doherty, Ryan Paul, Jennie Harré Hindmarsh, Kerry Macaskill-Smith, Brandon Orr-Walker, Rinki Murphy

“…The objective of this study was to test whether glycaemic response to representative treatments of dipeptidyl peptidase-4 inhibitors (vildagliptin) and thiazolidinediones (pioglitazone) varies according to ethnicity, gender, baseline obesity, triglyceride level or genetic variation.Methods This is a multicentre, two-period, two-treatment, open-label, randomised cross-over trial of vildagliptin and pioglitazone as second-line or third-line therapy in patients with T2D who have suboptimal glycaemic control on metformin and/or sulfonylurea therapy. It is conducted in New Zealand with a target of 300 patients (40% with Māori or Pacific ancestry) eligible if aged ≥18 and ≤80 years, with T2D for more than 1 year, on stable doses of metformin and/or sulfonylurea for at least 3 months, with HbA1c between 59 and 110 mmol/mol inclusive. …”
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Treatment Efficacy and Compliance in Patients with Diabetic Macular Edema Treated with Ranibizumab in a Real-Life Setting by Anne-Laurence Best, Franck Fajnkuchen, Sylvia Nghiem-Buffet, Typhaine Grenet, Gabriel Quentel, Corinne Delahaye-Mazza, Salomon Y. Cohen, Audrey Giocanti-Aurégan

“…A retrospective study was conducted in DME patients treated with ranibizumab. …”
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Screening for social anxiety disorder in students of Jordan universities after COVID-19 pandemic: a cross-sectional survey study by Abdallah Y Naser, Othman Beni Yonis, Ahlam J Alhemedi, Hadeel Allan, Ghalia abu Mohsen, Ayham Almasri, Haitham Abdulrazzeq, Islam Khasawneh, Osama El-khateeb

“…Objective To examine the prevalence rate of social anxiety disorder (SAD) among university students in Jordan after the COVID-19 pandemic and its associated predictors.Design A cross-sectional online survey study that was conducted in Jordan between January and December 2023.Setting: Universities in Jordan.Participants Healthy university students from any specialty currently enrolled at a Jordanian university.Primary outcome measure The prevalence rate of SAD, which was assessed using the Social Phobia Inventory.Results A total of 851 university students participated in this study. …”
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A comprehensive analysis of the effect of quorum-sensing molecule 3-oxo-C12-homoserine lactone on Candida auris and Candida albicans by Fruzsina Kovács, Ágnes Jakab, Noémi Balla, Zoltán Tóth, Dávid Balázsi, Lajos Forgács, Andrea Harmath, Aliz Bozó, Ágota Ragyák, László Majoros, Renátó Kovács

“…To gain deeper insights into this relationship, phenotypic and transcriptomic analyses were conducted in the presence of the primary P. aeruginosa quorum-sensing molecule, N-(3-oxododecanoyl)-l-homoserine lactone (HSL), against C. auris, with the results compared to those of C. albicans. …”
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Leveraging Non-Covalent Adaptable Networks to Stabilize Drug-Polymer Systems in Supersaturated Solutions: A Computational and Experimental Approach by Arif Budiman, Taufik Muhammad Fakih, Sandra Megantara, Muchtaridi Muchtaridi, Diah Lia Aulifa

“…Simultaneously, wet lab experiments were conducted to measure the nucleation induction times and observe the crystallization behavior of RTV under varying conditions of polymer presence. …”
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The JADES Transient Survey: Discovery and Classification of Supernovae in the JADES Deep Field by Christa DeCoursey, Eiichi Egami, Justin D. R. Pierel, Fengwu Sun, Armin Rest, David A. Coulter, Michael Engesser, Matthew R. Siebert, Kevin N. Hainline, Benjamin D. Johnson, Andrew J. Bunker, Phillip A. Cargile, Stephane Charlot, Wenlei Chen, Mirko Curti, Shea DeFour-Remy, Daniel J. Eisenstein, Ori D. Fox, Suvi Gezari, Sebastian Gomez, Jacob Jencson, Bhavin A. Joshi, Sanvi Khairnar, Jianwei Lyu, Roberto Maiolino, Takashi J. Moriya, Robert M. Quimby, George H. Rieke, Marcia J. Rieke, Brant Robertson, Melissa Shahbandeh, Louis-Gregory Strolger, Sandro Tacchella, Qinan Wang, Christina C. Williams, Christopher N. A. Willmer, Chris Willott, Yossef Zenati

“…At this depth, the detection rate is ∼1–2 arcmin ^–2 yr ^–1 , demonstrating the power of JWST as an SN discovery machine. We also conducted multiband follow-up NIRCam observations of a subset of the SNe to better constrain their light curves and classify their types. …”
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Chaetoceros muelleri sulfated polysaccharides: chain conformation, physical characteristics, and morphology by Valeria Miranda-Arizmendi, Jorge Marquez-Escalante, Agustin Rascon-Chu, Karla Martínez-Robinson, Francisco Brown-Bojorquez, Elizabeth Carvajal-Millan

“…The sample's zeta potential (ζ), conductivity, and diffusion coefficient (D) were −26.43 mV, −2.07 µm cm/s V, 1.25 mS/cm, and 1.8 × 10−8 cm2/s, correspondingly. …”
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Effect of Flowering Shading on Grain Yield and Quality of Durum Wheat in a Mediterranean Environment by Giancarlo Pagnani, Alfredo Lorenzo, Nausicaa Occhipinti, Lisa Antonucci, Sara D’Egidio, Fabio Stagnari, Michele Pisante

“…Field experiments were conducted in Mosciano Sant’Angelo, Italy, over two cropping seasons (2016–2017 and 2017–2018) to evaluate the effects of photosynthetically active radiation (PAR) availability and nitrogen (N) fertilization on durum wheat. …”
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Contemporaneous Emotion Regulation Theoretical Models: A Systematic Review by Camila Florencia Cremades, Cristian Javier Garay, Martín Juan Etchevers, Roberto Muiños, Graciela Mónica Peker, Juan Martín Gómez Penedo

“…It seeks to identify the main processes considered when working with emotional dysregulation. Method: Our team conducted a systematic review in the form of a narrative synthesis following the guidelines of the PRISMA statement. …”
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Collection of SARS-CoV-2 Virus from the Air of a Clinic within a University Student Health Care Center and Analyses of the Viral Genomic Sequence by John A. Lednicky, Sripriya N. Shankar, Maha A. Elbadry, Julia C. Gibson, Md. Mahbubul Alam, Caroline J. Stephenson, Arantzazu Eiguren-Fernandez, J. Glenn Morris, Carla N. Mavian, Marco Salemi, James R. Clugston, Chang-Yu Wu

“…A pilot SARS-CoV-2 air sampling study conducted at a clinic within a university student health care center detected the virus vRNA, with an estimated concentration of 0.87 virus genomes L−1 air. …”
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Temporal and habitat-specific variations in drivers of aboveground biomass dynamics in a Chinese subtropical forest by Yuxuan Bian, Qi Wu, Rong Zheng, Jiaqin Fu, Jianhua Chen, Xiangcheng Mi, Mingjian Yu, Yunquan Wang, Yunquan Wang, Yunquan Wang

“…To address this gap, we evaluated changes in aboveground biomass across a decade and various habitats, disentangling the relative influences of topography and multidimensional diversity on ΔAGB through datasets from forest inventories conducted between 2007 and 2017, along with phylogenetic relatedness, functional traits, and environmental variables from a subtropical forest in China. …”
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Assessing patient risk, benefit and outcomes in drug development: an observational study of regorafenib clinical trials by Matt Vassar, Vinay Prasad, Ryan McIntire, Alyson Haslam, Brody Dennis, Chance Bratten, Griffin K Hughes, Andriana M Peña, Chase Ladd, Brooke Gardner, William Nowlin, Reagan Livingston, Jordan Tuia

“…The amount of non-randomised, single-arm trials in our sample size was concerning, indicating that higher quality research must be conducted. Our results propose that regorafenib’s efficacy and safety may be more impactful in cancers other than its FDA approvals.…”
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HIV Drug Resistance Profile in Clients Experiencing Treatment Failure After the Transition to a Dolutegravir-Based First-Line Antiretroviral Treatment Regimen in Mozambique by Nalia Ismael, Cidia Hussein, Cacildo Magul, Humberto Inguane, Aleny Couto, Amancio Nhangave, Ana Muteerwa, Mahoudo Bonou, Artur Ramos, Peter Wesley Young, Sonia Chilundo, Rhoderick Machekano, Lauren Greenberg, Juliana da Silva, Nilesh Bhatt

“…A cross-sectional study was conducted in Gaza, Mozambique (August 2021–February 2022), including adults on first-line ART for ≥12 months who transitioned to TLD and had unsuppressed viral load (VL) ≥ 1000 copies/mL six months post-transition. …”
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Associations of lamplight exposure during sleep and sleep duration with attention-deficit/hyperactivity disorder among preschool children in China by Hui Jiang, Bin Yu, Yuanyang Liu, Hui Gao, Ruijuan Song, Siyue Tan, Shufen Han, Hui Zuo, Hui Zuo, Hui Zuo

“…IntroductionThis study aimed to examine the associations of exposure to light while sleeping at night and different sleep durations with attention-deficit/hyperactivity disorder (ADHD) among preschool children in China.MethodsA cross-sectional study including 4197 preschool children (2190 boys and 2007 girls) was conducted in 2021. Lamplight exposure during sleep and sleep duration were collected via a validated questionnaire. …”
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The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review by Theodoros Karampitsakos, Despoina Mavrogianni, Nikolaos Machairiotis, Anastasios Potiris, Periklis Panagopoulos, Sofoklis Stavros, Panos Antsaklis, Peter Drakakis

“…Methods: To address this issue, a literature review has been conducted on PubMed/Medline and Scopus databases for articles investigating the possible correlation between IL6, IL8, and MMP9 and preterm labor. …”
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The correlation between coagulation biomarkers, bone turnover markers, and bone mineral density in Chinese adults aged ≥ 50 years by Zhengming Wang, Rui Wang, Haiya Ge, Yong Gu, Sicheng Xian, Laijun Yan, Guoqing Du, Zhibi Shen, Shuaijie Lv, Hongsheng Zhan, Zhengyan Li

“…Finally, multivariable regressions were conducted to adjust for differences in demographics and comorbidities among groups. …”
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Heterogeneity of cancer-associated fibroblast subpopulations in prostate cancer: Implications for prognosis and immunotherapy by Chen Ding, Jiange Wang, Jie Wang, Jiqiang Niu, Zhikai Xiahou, Zhou Sun, Zhenzhen Zhao, Dongyang Zeng

“…Our analysis identified four predominant subsets: C0 IER2+, C1 ABCA8+, C2 ABI3BP+, and C3 MEOX2+. We conducted comprehensive gene expression profiling to construct a robust prognostic model reflecting the clinical relevance of these subpopulations. …”
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Evaluating NfL and NTproBNP as predictive biomarkers of intracranial injuries after mild traumatic brain injury in children presenting to emergency departments by Anne-Cécile Chiollaz, Virginie Pouillard, Michelle Seiler, Céline Habre, Fabrizio Romano, Céline Ritter Schenck, Fabian Spigariol, Christian Korff, Fabienne Maréchal, Verena Wyss, Lyssia Gruaz, Joan Montaner, Jean-Charles Sanchez, Sergio Manzano

“…We aim to assess the performances of two routinely used biomarkers in other fields: the neurofilament light chain protein (NfL), and the N-terminal prohormone of brain natriuretic peptide (NTproBNP), to safely discharge children without intracranial injuries (ICIs).MethodsA prospective multicenter cohort study was conducted, enrolling children suffering from mTBI, both with and without imaging during their acute management in the PED. …”
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