Neuroprotective effects of quercetin on hippocampal CA1 neurons following middle cerebral artery ischemia‒reperfusion in male rats: a behavioral, biochemical, and histological stud... by Mehran Mahyar, Erfan Ghadirzadeh, Pedram Nezhadnaderi, Zahrasadat Moayedi, Parniyan Maboud, Arvin Ebrahimi, Ali Siahposht-Khachaki, Narges Karimi

“…Various assessments, including brain water content, the rotarod test, the Bederson neurological score, the Morris water maze (MWM) test, the shuttle box test, histopathological evaluations, and measurements of interleukin-10 (IL-10) and interleukin-1β (IL-1β) levels, were conducted across the groups. Results Compared with control rats, 5 and 10 mg/kg quercetin-treated rats presented significant improvements in brain water content, neurological function, and motor function and improved performance in the MWM and shuttle box tests. …”
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Screening of two efficient phosphorus-solubilizing bacteria, strain X42 (Bacillus_A_bombysepticus) and strain G62 (Bacillus velezensis) for their ability to promote Gan Nan navel o... by Wenyuan Zhao, Tao Peng, Haojie Cao, Huimin Huang, Shuijing Yu

“…Furthermore, whole-genome sequencing of the two strains was conducted, and by comparing data from 31 housekeeping genes, strain X42 was preliminarily identified as Bacillus bombysepticus, and strain G62 was identified as Bacillus velezensis. …”
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Volume contracted state, mortality and functional outcomes in patients with acute ischaemic stroke due to large vessel occlusion by Risheng Xu, Max Wintermark, Gregory W Albers, Jeremy J Heit, Adam A Dmytriw, Adrien Guenego, Yasmin Aziz, Kambiz Nael, Benjamin Pulli, Victor Urrutia, Dhairya A Lakhani, Tobias D Faizy, Argye Hillis, Vivek Yedavalli, Dylan Wolman, Licia P Luna, Elisabeth B Marsh, Hamza Adel Salim, Janet Mei, Vaibhav Vagal, Aakanksha Sriwastwa, Raf Llinas, Hanzhang Lu, Mona N Bahouth

“…This study investigates the association between VCS and clinical outcomes in patients with AIS due to large vessel occlusion (LVO).Methods A retrospective cohort study was conducted involving 298 patients with LVO-AIS from two comprehensive stroke centres. …”
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Acceptability and Attitude towards a Mobile-Based Home Exercise Program among Stroke Survivors and Caregivers: A Cross-Sectional Study by Amreen Mahmood, Vevita Blaizy, Aparajita Verma, Joel Stephen Sequeira, Dola Saha, Selvam Ramachandran, N. Manikandan, Bhaskaran Unnikrishnan, John M. Solomon

“…A cross-sectional study was conducted among 102 participants to understand their attitude and acceptability towards mobile-based home exercise program. …”
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The Age–Velocity Dispersion Relations of the Galactic Disk as Revealed by the LAMOST-Gaia Red Clump Stars by Weixiang Sun, Han Shen, Biwei Jiang, Xiaowei Liu

“…Using nearly 230,000 red clump stars selected from LAMOST and Gaia, we conduct a comprehensive analysis of the stellar age–velocity dispersion relations (AVRs) for various disk populations, within 5.0 ≤ R ≤ 15.0 kpc and ∣ Z ∣ ≤ 3.0 kpc. …”
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Amniotic fluid microbiota and metabolism with non-syndromic congenital heart defects: a multi-omics analysis by Wenli Xu, Lu Li, Hong Kang, Meixian Wang, Yanqun Liu, Guicun Wang, Ping Yu, Juan Liang, Zhen Liu

“…Methods and results A case-control study was conducted with 17 cases diagnosed with non-syndromic CHDs (CHDs group) and 34 controls without congenital anomalies (control group) at a ratio of 1:2. …”
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Evaluation of Serum Leucine-Rich Alpha-2 Glycoprotein as a New Inflammatory Biomarker of Inflammatory Bowel Disease by Tetsuhiro Yoshimura, Keiichi Mitsuyama, Ryosuke Sakemi, Hidetoshi Takedatsu, Shinichiro Yoshioka, Kotaro Kuwaki, Atsushi Mori, Shuhei Fukunaga, Toshihiro Araki, Masaru Morita, Kozo Tsuruta, Hiroshi Yamasaki, Takuji Torimura

“…A large-scale well-designed study should be conducted in the future to more accurately reveal the clinical significance of LRG in patients with IBD.…”
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Overexpression of OsDUF868.12 enhances salt tolerance in rice by Hao Chen, Jiale Wan, Jiali Zhu, Ziyi Wang, Caiyao Mao, Wanjing Xu, Juan Yang, Yijuan Kong, Xiaofei Zan, Rongjun Chen, Jianqing Zhu, Zhengjun Xu, Lihua Li, Lihua Li

“…A series of experiments, including RT-qPCR, Agrobacterium-mediated transient transformation in tobacco for localization analysis, phenotypic characterization, physiological and biochemical index measurement, and leaf staining, were conducted to investigate the function of OsDUF868.12 under salt stress. …”
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Assessing the association between tourism and the alcohol urban environment in Barcelona: a cross-sectional study by Xisca Sureda, Manuel Franco, Susanna Puigcorbé, Joan R Villalbí, Marina Bosque-Prous, Ester Teixidó-Compañó, Montserrat Bartroli, Albert Espelt

“…We explore with a valid instrument in a large city whether there is an association between high tourism pressure and a greater presence of alcohol-related elements in the urban environment.Design Observational ecological study.Setting The study was conducted in Barcelona during 2017–2018.Participants We assessed urban exposure to alcohol by performing social systematic observation using the OHCITIES Instrument in a stratified random sample of 170 census tracts within the city’s 73 neighbourhoods.Primary and secondary outcome measures For each census tract we calculated the density of alcohol premises, and of promotion in public places per 1000 residents. …”
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Breast cancers with neuroendocrine differentiation: Retrospective case studies series from a single institution based on the 2019 WHO classification by Youngkyung Jeon, Ji-Yeon Kim, Jin Seok Ahn, Young-Hyuck Im, Kyuehee Choi, Sun Young Jeong, Yeji Jung, Jaeyeon Jang, Dae-Ho Choi, Joohyun Hong, Hyo Jung Kim, Soo Youn Cho, Yeon Hee Park

“…Based on the updated classification of the NEN, we conducted a case series using the Clinical Data Warehouse platform of SMC. …”
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Visual electrophysiological assessment of children with poor response to treatment for functional amblyopia by Dong-Qing Yuan, Wei-Wei Zhang, Liu-Wei Gu, Qing-Huai Liu

“…Spectral domain-optical coherence tomography (SD-OCT) and multifocal electroretinography (mfERG) were conducted to analyze the macular retinal thickness and the first-order response P1 ring of the mfERG in the amblyopic eye (AE) compared to the fellow good eye (GE). …”
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Age-specific abnormal glucose metabolism in HIV-positive people on antiviral therapy in China: a multicenter case-control study by Lijun Xu, Mengsha Chen, Chunhui Yan, Xiaofeng Li, Xiaoli Ni, Minghang Zhou, Weiwei Xu, Junfang Xu, Shigui Yang

“…This study aims to investigate the impact of HIV infection on AGM, including insulin resistance (IR), impaired fasting glucose (IFG), and diabetes mellitus (DM).Methods A multicenter case-control study was conducted in Zhejiang province, China. After matching, the study included 1030 people living with HIV (PLWH) and 1030 people living without HIV (PLWTH). …”
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Salidroside promotes pro-angiogenesis and repair of blood brain barrier via Notch/ITGB1 signal path in CSVD Model by Tu Zhilan, Zhang Zengyu, Jin Pengpeng, Yang Hualan, Li Chao, Xi Yan, Guo Zimin, Hou Shuangxing, Li Weiwei

“…Subsequently, the MRI, pathomorphism, as well as Morriss water maze test were conducted to determine CSVD-related indicators. 8 weeks post-surgery, animals were randomly administered SAL, DAPT, ATN161 or saline.The aim was to explore the protective effects of SAL in CSVD as well as its possible mechanism. …”
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Practice and factors affecting informed consent among healthcare workers for major surgical procedures at Gurage zone hospitals, South Ethiopia, 2022: a facility-based cross-sectio... by Haimanot Abebe, Bitew Tefera Zewudie, Yibeltal Mesfin, Shegaw Geze Tenaw, Daniel Tsega, Bogale Chekole, Zebene Mekonnen, Shegaw Tesfa Mengist, Agere Aynalem, Tadele Lankrew, Yihenew Sewale, Muche Argaw, Tadesse Sahle

“…Objective This study aimed to assess the informed consent practice process and associated factors among healthcare workers for major surgical procedures at Gurage zone hospitals, in 2022.Methods and materials Institution-based cross-sectional study was employed.Settings This study was conducted in Gurage zone hospitals.Participants All healthcare workers who have been working in Gurage zone hospitals of surgical, operation rooms and obstetrics/gynaecology wards had exposure to patients who had undergone surgery during the study periodOutcome The primary outcome of the study was the practice of informed consent practice among healthcare workers in Gurage zone hospitals.Result A total of 448 study participants were involved in this study giving a response rate of 98%. …”
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Molecular Characterization of a Multidrug-Resistant Klebsiella pneumoniae Strain R46 Isolated from a Rabbit by Fei Wu, Yuanyuan Ying, Min Yin, Yi Jiang, Chongyang Wu, Changrui Qian, Qianqian Chen, Kai Shen, Cong Cheng, Licheng Zhu, Kewei Li, Teng Xu, Qiyu Bao, Junwan Lu

“…A conjugation experiment was conducted to assess the transferability of the resistance plasmids. …”
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Changes in Methylation Patterns of Tumor Suppressor Genes during Extended Human Embryonic Stem Cell Cultures by Kyung Min Kang, Jeoung Eun Lee, Ji Eun Park, Hyunjin Kim, Hee Yeon Jang, Minyeon Go, Dong Ryul Lee, Sung Han Shim

“…While studies on embryonic stem cells have been actively conducted, little is known about the epigenetic mechanisms in human embryonic stem cells (hESCs) in extended culture systems. …”
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Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection [version 2; peer review: 2 approved] by Raasti Naseem, Sara Pretorius, Nicola Howe, Clare Lendrem, Cameron Williams, Enitan D Carrol, Philip Pallmann

“…The platform will assess their comparative clinical effectiveness and cost-effectiveness relative to current standard of care. Preliminary work, conducted under a Health Technology Assessment Application Acceleration Award, provided key evidence to optimise the design of the PROTECT platform. …”
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The effects of psychosocial and economic factors on the quality of life of patients with end-stage renal disease and their caregivers in Klang Valley, Malaysia: protocol for a mixe... by Norhayati Ibrahim, Sin Yee Chu, Ching Sin Siau, Noh Amit, Rozmi Ismail, Abdul Halim Abdul Gafor

“…Despite the current circumstances, there are very few studies in Malaysia that have explored the psychosocial factors, specifically on the economic impact of the management of ESRD.Methods and analysis This two-phase sequential explanatory mixed-methods design, incorporating a quantitative design (phase I) and a qualitative study (phase II), is to be conducted in 4 government hospitals and 10 other non-governmental organisations or private dialysis centres within Klang Valley, Malaysia. …”
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Influence of sediment additions on the mechanical behavior of fiber-reinforced concrete in aggressive environments by Louafi Goudih, Hamid Sellaf, Benamar Balegh, Ali Meksi, Adda Hadj Mostefa, Mohamed Elamine Dahamni

“…The performance of such concrete was evaluated through compressive strength tests conducted for 28 days. Durability was assessed by exposing the concrete to chemical attacks from hydrochloric acid (HCl), sulfuric acid (H₂SO₄), and sodium sulfate (Na₂SO₄) solutions. …”
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Maintaining Fat-Free Mass and Muscle Mass during obesity therapy with Incretin-Mimetic Drugs by Dariusz Popiela, Karina Urbańska, Łukasz Stojak, Mateusz Grego, Filip Kwiatkowski, Mateusz Baczewski, Katarzyna Grego, Witold Czyż

“…This study aims to analyze current information about strategies that minimize the loss of FFM and MM and muscle function and consider using methods to prevent muscle atrophy in patients treated for obesity with other methods, such as diet, exercise, and bariatric surgery, to form a holistic approach for patients treated with IMDs. This review was conducted by searching scientific publications on PubMed, Google Scholar, and Clinicaltrials.gov databases. …”
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