Experiences of ‘traditional’ and ‘one-stop’ MRI-based prostate cancer diagnostic pathways in England: a qualitative study with patients and GPs by Fiona M Walter, Stephanie Archer, Willie Hamilton, Samuel William David Merriel, John McGrath, Alice S Forster, Hashim Uddin Ahmed, David Eldred-Evans

“…Objectives This study aimed to understand and explore patient and general practitioner (GP) experiences of ‘traditional’ and ‘one-stop’ prostate cancer diagnostic pathways in England.Design Qualitative study using semi-structured interviews, analysed using inductive thematic analysisSetting Patients were recruited from National Health Service (NHS) Trusts in London and in Devon; GPs were recruited via National Institute for Health Research (NIHR) Clinical Research Networks. Interviews were conducted in person or via telephone.Participants Patients who had undergone a MRI scan of the prostate as part of their diagnostic work-up for possible prostate cancer, and GPs who had referred at least one patient for possible prostate cancer in the preceding 12 months.Results 22 patients (aged 47–80 years) and 10 GPs (6 female, aged 38–58 years) were interviewed. …”
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Seedling Stage Corn Line Detection Method Based on Improved YOLOv8 by LI Hongbo, TIAN Xin, RUAN Zhiwen, LIU Shaowen, REN Weiqi, SU Zhongbin, GAO Rui, KONG Qingming

“…Comparative tests were conducted to evaluate multiple backbone networks within the YOLOv8 framework, and ablation studies were performed to validate the enhancements made in YOLOv8-G.…”
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Recipient and instructor perspectives of an adapted exercise-based fall prevention programme for adults aged 50+ years with vision impairment: a qualitative study nested within a r... by Lisa Keay, Lindy Clemson, Helen Nguyen, Lisa Dillon, Kirsten Bonrud Jakobsen, Jodi Martin, Frances Tinsley

“…Therefore, the purpose of this study, nested within an ongoing randomised controlled trial (RCT), is to document the adaptation of an existing fall prevention programme and investigate the perspectives of instructors involved in delivery and the older adults with vision impairment receiving the programme (recipients).Design We documented programme adaptations and training requirements, and conducted semistructured, individual interviews with both the instructors and the recipients of the programme from 2017 to 2019. …”
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Impact of solid fuel use on asthma prognosis and consistent peak expiratory flow changes: Evidence from China by Yuexi Chen, Shuojia Xie, Xirong Chen, Xiaowen Zhong, Linhang Yang, Weitong Lin, Junfeng Huang, Ruchong Chen

“…This investigation endeavors to conduct an integrative cross-sectional and longitudinal study to examined the link between solid fuel utilization and asthma. …”
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Development of quality indicators for hand osteoarthritis care – Results from an European consensus study by Daniel H. Bordvik, Yeliz Prior, Rachael Bamford, Francis Berenbaum, Mathilda Björk, Thalita Blanck, Barbara Slatkowsky Christensen, Krysia Dziedzic, John Edwards, Nazemin Gilanliogullari, Carol Graham, Ida K. Haugen, Margreet Kloppenburg, Hellen Laheij, Marco J.P.F. Ritt, Tanja Stamm, Anne Therese Tveter, Nina Østerås, Ingvild Kjeken

“…Cognitive debriefing interviews with Norwegian and UK hand OA patients were conducted to ensure clarity. Results: Our initial literature search provided 1670 articles, with none describing relevant QIs. …”
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Protective Role of Genistein in Acute Liver Damage Induced by Carbon Tetrachloride by Nalan Kuzu, Kerem Metin, Adile Ferda Dagli, Fatih Akdemir, Cemal Orhan, Mehmet Yalniz, Ibrahim Hanifi Ozercan, Kazim Sahin, Ibrahim Halil Bahcecioglu

“…A histopathological examination was conducted. Results. Liver tissue MDA levels were found significantly lower in group 3, in comparison to group 2 (P<.05). …”
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TAS2R38 genotype and CRS severity in children with cystic fibrosis by Elena Cantone, Antonella Tosco, Angela Sepe, Valeria Raia, Rossella Negri, Alice Castaldo, Chiara Cimbalo, Paolo Pezzella, Mario Brandon Russo, Giusi Grimaldi, Claudio Di Nola, Luigi Greco

“…Background: Cystic fibrosis is a heterogeneous disease whose severity and symptoms largely depend on the functional impact of mutations in the cystic fibrosis transmembrane conductance regulator gene. Other genes may also modulate the clinical manifestations and complications associated with cystic fibrosis. …”
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Persistence of gastrointestinal symptoms in irritable bowel syndrome and ulcerative colitis: study protocol for a three-arm randomised controlled trial (SOMA.GUT-RCT) by Ansgar W Lohse, Bernd Löwe, Kerstin Maehder, Yvonne Nestoriuc, Antonia Zapf, Eik Vettorazzi, Viola Andresen, Sina Hübener, Luisa Peters

“…Our primary hypothesis is that persistent gastrointestinal symptoms in UC and IBS can be improved by modifying dysfunctional symptom expectations and illness-related anxiety using expectation management strategies.Methods and analysis To assess the extent to which persistent somatic symptoms are modifiable in adult patients with UC and IBS, we will conduct an observer-blinded, three-arm randomised controlled trial. …”
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Higher incidence of postoperative complications in patients with simultaneous patellar tendon and anterior cruciate ligament ruptures following single surgery: a case series and li... by Hao-ran Su, Xi Gong, Cheng Wang, Hai-jun Wang, Yi-Tian Gao, Jian Wang, Yong Ma, Jian-quan Wang, Wei-li Shi

“…However, due to the limited cases, the design of previous studies was mostly case report with varying conclusions regarding recommended surgical strategy selection, the optimal surgical strategy remains a subject of debate. Methods We conducted a retrospective case series and literature review, including 10 cases from local institution and 27 cases from 17 studies. …”
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Bidirectional association between physical activity and depression: the “Como Vai?” cohort study by Bárbara Sutil da Silva, Debora Tornquist, Andrea Wendt, Andréa Dâmaso Bertoldi, Elaine Tomasi, Maria Cristina Gonzalez, Renata Moraes Bielemann, Inácio Crochemore-Silva

“…This is a cohort study called “Como Vai?” (How are you?), conducted by older population representative sample of the city of Pelotas-Rio Grande do Sul. …”
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Mycological Profile and Associated Factors Among Patients with Dermatophytosis in Astana, Kazakhstan by Alma Aimoldina, Ainura Smagulova, Gulnar Batpenova, Nellie Konnikov, Togzhan Algazina, Zulfiya Jetpisbayeva, Dinara Azanbayeva, Darkhan Amantayev, Vladimir Kiyan

“…Statistical analysis was conducted using SPSS version 26. The overall prevalence of dermatophytosis in the cohort was 30.4%. …”
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Assessment of Seismic Vulnerability for a Hospital Building Using Field Data and Various Numerical Analyses Considering Bidirectional Ground Motion Effects by Alireza Kharazian, Arianna Guardiola-Villora, Juan José Galiana-Merino, Sergio Molina, Gonzalo Ortuño-Sáez, Juan Luís Soler-Llorens, José Antonio Huesca-Tortosa, Igor Gómez, David Montiel-López

“…Furthermore, the study carefully selects ground motion records representing two limit states—Damage Limitation (DL) and Severe Damage (SD)—to conduct an extensive seismic analysis. In each limit state applied to the structure, there are 14 bidirectional ground motions with components alternately directed along the two principal directions of the building. …”
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Serum 25(OH)D Level and Parathyroid Hormone in Chinese Adult Population: A Cross-Sectional Study in Guiyang Urban Community from Southeast of China by Zhang Qiao, Shi Li-xing, Peng Nian-chun, Xu Shu-jing, Zhang Miao, Li Hong, Zhuang Hui-jun, Gong Ming-xian, Zhang Song, Wang Rui, Hu Ying, Zhang Jing-lu, Chen Shuang

“…Design and Participants. We conducted a cross-sectional evaluation in the General Community in Guiyang by cluster sampling method. …”
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Performance of sulfur/steel slag composite matrix in removing nitrate from surface water with low-carbon content by PENG Xianchun, ZHENG Lili, LU Haoran, WANG Zhefeng, ZHU Zheng, LIANG Wenyan

“…Anaerobic bottle batch experiments were conducted to compare the denitrification performance of sulfur/steel slag and sulfur/limestone systems. …”
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The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells by Shuhd Bin Eshaq, Jalal Taneera, Shabana Anjum, Abdul Khader Mohammed, Mohammad H. Semreen, Karem H. Alzoubi, Mohamed Eladl, Yasser Bustanji, Eman Abu-Gharbieh, Waseem El-Huneidi

“…Additionally, functional experiments were conducted in INS-1 cells, a rat β-cell line, to elucidate the role of Ahr in β-cell biology. …”
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The impact of oxidative balance on all-cause and cause-specific mortality in US adults and cancer survivors: evidence from NHANES 2001–2018 by Juan Wu, Yingdong Han, Menghui Yao, He Zhao, Zhikai Li, Tiange Xie, Yun Zhang, Xuejun Zeng

“…Stratified analyses were conducted to further refine the findings. Results During a mean follow-up of 9.1 years, 5,092 deaths occurred. …”
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Kinetic and Photochemical Disequilibrium in the Potentially Carbon-rich Atmosphere of the Warm Jupiter WASP-69 b by Nidhi Bangera, Christiane Helling, Gloria Guilluy, Patricio Cubillos, Luca Fossati, Paolo Giacobbe, Paul Rimmer, Daniel Kitzmann

“…We utilize nonequilibrium gas-phase simulations to conduct a parameter study for vertical diffusion strength, local gas temperature, and C/O ratio. …”
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Extremely early initiation of vasopressors might not decrease short-term mortality for adults with septic shock: a systematic review and meta-analysis by Cheng-Hsin Ma, Jack Healy, Ebrima Kinteh, Cheng-Chin Ma, Ching-Fang Tiffany Tzeng, Eric H. Chou, Chin-Chieh Wu, Shih-Chieh Shao, Kuan-Fu Chen

“…Methods A systematic review and meta-analysis were conducted by searching PubMed, Embase, and Cochrane databases. …”
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Improving Autonomous Vehicle Cognitive Robustness in Extreme Weather With Deep Learning and Thermal Camera Fusion by Mehmood Nawaz, Sheheryar Khan, Muhammad Daud, Muhammad Asim, Ghazanfar Ali Anwar, Ali Raza Shahid, Ho Pui Aaron HO, Tom Chan, Daniel Pak Kong, Wu Yuan

“…This is evident from tests conducted on two public datasets (FLIR and TarDAL) and one private dataset (CUHK).…”
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Role of nasal microbiota in regulating host anti-influenza immunity in dogs by Jinzhu Geng, Yuhao Dong, Hao Huang, Xia Wen, Ting Xu, Yanbing Zhao, Yongjie Liu

“…Also, the majority of these studies have been conducted on murine models, and it remains unclear how far these findings can be extrapolated from murine models to other animals. …”
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