Insufficient gene expression and lost gene regulatory network may underlie the mechanism of Hirschsprung Disease in 5p–syndrome by Yizhao Luan, Peng Li, Yuanyuan Luo, Hong Zhang, Xiaochun Zhu, Yan Zhang, Aihua Yin, Qiang Wu, Chengwei Chai

“…However, the genetic basis of many specific phenotypes, including the co-occurrence of Hirschsprung Disease (HSCR), have yet been clarified. Here, we conducted a study on two patients with CDC and HSCR using whole genome sequencing (WGS) analyses. …”
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Development of a model for detection and analysis of inclusions in tomographic images of iron castings using decision trees by Dorota Wilk-Kołodziejczyk, Aleksandra Nowotny, Izabela Krzak, Adam Tchórz, Krzysztof Jaśkowiec, Marcin Małysza, Adam Bitka, Mirosław Głowacki, Marzanna Książek, Łukasz Marcjan

“…On these images, objects can be identified that can be considered as graphite precipitates or indicate the presence of a defect in the casting. Research conducted in this area is described, based on experimental data that allows to determine whether the indicated components present in the casting are graphite precipitation. …”
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Is Everyone Beating Around the Bush?: A Qualitative Study Examining the Status of Shared Decision-Making Between Veterans Affairs Providers and Surgical Patients in the ICU by M. Andrew Millis, MD, MPH, C. Ann Vitous, MA, MPH, Cara Ferguson, BS, Maedeh Marzoughi, BS, Erin Kim, BS, Sarah E. Bradley, PhD, MPH, CPH, Ashley Duby, MS, Pasithorn A. Suwanabol, MD, MS

“…Qualitative interviews were conducted with providers who provide ICU-level care to surgical patients in Veterans Affairs hospitals. …”
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Exploring the general practitioners’ perception of the inter-professional care of rheumatoid arthritis patients (GEPRA—II): a qualitative interview study by Anne-Laure Yailian, Audrey Janoly-Dumenil, Emmanuelle Vignot, Aurélie Fontana, Charline Estublier, Cyrille Confavreux, Roland Chapurlat, Claude Dussart, Humbert de Freminville

“…Methods A qualitative semi-structured study using face-to-face or telephone interviews was conducted. Eligible participants included French GPs referring patients with RA. …”
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Single-cell sequencing uncovers the mechanistic role of DAPK1 in glioma and its diagnostic and prognostic implications by Tian-Hang Yu, Yan-Yu Ding, Yan-Yu Ding, Si-Guo Zhao, Jie-Hui Zhao, Yu Gu, Dong-Hui Chen, Fang Zhang, Wen-Ming Hong, Wen-Ming Hong

“…BackgroundWe conducted an investigation into the characteristics of single-cell differentiation data in gliomas, with a focus on developing DAPK1-based prognostic markers to predict patient outcomes. …”
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Which Positions Optimize Pelvic Floor Activation in Female Athletes? by Elena Sonsoles Rodríguez-López, Luz María Martín-Márquez, María Barbaño Acevedo-Gómez, África López-Illescas, María Benito-de-Pedro, Cristina Ojedo-Martín

“…Methods: An observational and descriptive study was conducted with twenty-five female rugby players. Surface electromyography was used to evaluate the PFMs in five different body positions under stable and unstable conditions. …”
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The relationship between cognitive function and neuropsychiatric disorders with quantitative electroencephalogram (qEEG) on long COVID syndrome patients by Yetty Ramli, Pukovisa Prawiroharjo, Winnugroho Wiratman, Eric Tenda, Nurhadi Ibrahim, Damar Susilaradeya, Abdi Reza, Jennifer Agatha, Rejoel Siagian, Hazrina Fauhan, Florencia Evelyn, Yoshikazu Ugawa, Prasandhya Yusuf

“…Methods: This cross-sectional study compared patients with long COVID to those who had recovered from COVID-19 without residual symptoms using quantitative electroencephalogram (qEEG) analysis. We conducted qEEG analyses, and Montreal Cognitive Assessment (MoCA) and Self-Rating Questionnaire (SRQ) tests on participants. …”
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The Observed Phase Space of Mass-loss History from Massive Stars Based on Radio Observations of a Large Supernova Sample by Itai Sfaradi, Assaf Horesh, Rob Fender, Lauren Rhodes, Joe Bright, David Williams-Baldwin, Dave A. Green

“…This sample comprises both archival data and our new observations of 99 CCSNe conducted with the AMI-LA radio array in a systematic approach devised to constrain the mass loss at different stages of stellar evolution. …”
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Prevalence and impact of pelvic floor dysfunctions on quality of life in women 5–10 years after their first vaginal or caesarian delivery by Alba González-Timoneda, Nerea Valles-Murcia, Paula Muñoz Esteban, María Sol Torres López, Elisa Turrión Martínez, Patxi Errandonea Garcia, Lola Serrano Raya, Francisco Nohales Alfonso

“…Objective: Our aim was to investigate late prevalence, risk factors, and the impact on quality of life of PFD in women after their first vaginal or caesarian birth. Methods: We conducted an ambispective cohort observational study. …”
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Food Grade Nanofiber of Polylactic Acid by Electrospinning: Physicochemical Characterization of Solutions and Parameters of the Technique by Dalila Fernanda Canizales-Rodríguez, Francisco Rodríguez-Félix, José Agustín Tapia-Hernández, Carmen Lizette Del-Toro-Sánchez, Saúl Ruíz-Cruz, Santiago P. Aubourg, Daniela Denisse Castro-Enríquez, Carlos Gregorio Barreras-Urbina, Silvia Elena Burruel-Ibarra, José Luis Pompa-Ramos, Lorena Armenta-Villegas

“…The main objective of this work was to obtain food grade nanofibers (FGNs) of PLA (FGN-PLA) by electrospinning, for which different food grade solutions (FGSs) of PLA (FGS-PLA) concentrations with food grade solvent acetone (FGSA) were made and characterized via viscosity, density, conductivity, surface tension measurements, and rheological properties, and to correlate its effect on the FGN-PLA production by electrospinning as well as the effect of technique process parameters (distance from needle to collector plate and flow rate) on fiber characteristics was investigated. …”
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Prevalence of Hepatitis C Virus Among Hospitalized Patients in a Tertiary Hospital in Italy: The Basis for a National Screening Assessment Model? by Giulia Morsica, Massimo Locatelli, Gema Hernandez-Ibarburu, Francesca Rusconi, Alba Segovia-Hilara, Davide Di Napoli, Matteo Moro, Salvatore Mazzitelli, Hamid Hasson, Federico Esposti, Roberts Mazzuconi, Antonella Castagna

“…A retrospective study of hospitalized patients (PTs) tested for HCV Ab for 5 years (from January 2017 to December 2022) in San Raffaele hospital was conducted according to age categories: birth year group before 1947 (patients older than 76 years old), birth year group 1947–1968, birth year group 1969–1989, and two other groups with birth year groups 1990–2000 and 2001–2022 (with patients younger than 33 years old) using the TriNetX platform. …”
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Research on F10.7 Index Prediction Based on Factor Decomposition and Feature Enhancement by Shuainan Yan, Yanmei Cui, Bingxian Luo, Liqin Shi, Yanxia Cai

“…We incorporate additional features such as the soft X-ray flare index (FI _SXR ), magnetic type of the active region (new_Mag), and X-ray background flux (XBF) to enhance the understanding of the underlying physical processes of solar activity. Our experiments, conducted using advanced forecasting models on the SG-F10.7-All data set, validate the efficacy of our proposed strategy. …”
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Development of High Dietary Fiber Cereal Bar as Emergency Food Product and The Chemical-Microbiological Properties and Nutritional Content by Ani Radiati, Sumarto Sumarto, Fahmi Hafid, Emma Kamelia, Lia Nurcahyani, Dini Mariani, Siti Badriah, Tjahja Muhandri

“…Chemical analysis included dietary fiber, carbohydrates, protein, fat, minerals, and vitamins while the microbiological analysis covered total plate count (TPC) and detection of pathogenic bacteria such as Escherichia coli, Salmonella, and Staphylococcus aureus in accordance with food safety standards from the Indonesian Food and Drug Authority (BPOM). The testing was conducted from November 3–15, 2023, at PT Saraswanti Indo Genetech laboratory, Indonesia. …”
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The Canadian Bronchiectasis and Nontuberculous Mycobacteria Registry: a study protocol by Christina S. Thornton, Nicole Boechler, Vidhi Desai, Ranjani Somayaji, Swathi Purighalla, Sarah Brode, Theodore K. Marras, Ryan Cooper, Maeve Smith, Julie Jarand

“…While the most substantial cohort studies have been conducted in Europe and the USA, Canada also faces considerable challenges. …”
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Florfenicol Resistance in Enterobacteriaceae and Whole-Genome Sequence Analysis of Florfenicol-Resistant Leclercia adecarboxylata Strain R25 by Yuanyuan Ying, Fei Wu, Chongyang Wu, Yi Jiang, Min Yin, Wangxiao Zhou, Xinyi Zhu, Cong Cheng, Licheng Zhu, Kewei Li, Junwan Lu, Teng Xu, Qiyu Bao

“…The agar dilution method was conducted to determine the minimum inhibitory concentration (MIC) for florfenicol, and polymerase chain reaction (PCR) was performed to detect florfenicol resistance genes. …”
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Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment by Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon

“…However, specific virally-encoded epitopes and their corresponding immune responses are not fully defined.Methods To understand the OPSCC immune landscape, we conducted a comprehensive single-cell analysis of HPV16+ and HPV33+ primary tumors and metastatic lymph nodes. …”
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Viral diversity in wild rodents in the regions of Canaã de Carajás and Curionopólis, State of Pará, Brazil by Adriana Freitas Moraes Monteiro, Adriana Freitas Moraes Monteiro, Fábio Silva da Silva, Ana Cecília Ribeiro Cruz, Ana Cecília Ribeiro Cruz, Sandro Patroca da Silva, Alice Louize Nunes Queiroz, Livia Medeiros Neves Casseb, Livia Medeiros Neves Casseb, Livia Carício Martins, Livia Carício Martins, Daniele Barbosa de Almeida Medeiros, Daniele Barbosa de Almeida Medeiros

“…Subsequently, nucleotide sequencing and bioinformatics analyses were conducted on 14 selected samples to characterize the virome. …”
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Cochlear Implantation in Single-Sided Deafness and Asymmetric Hearing Loss: 12 Months Follow-up Results of a European Multicenter Evaluation by Thomas Wesarg, Antje Aschendorff, Regina Baumgaertel, Julia Böttcher, Liesbeth De Coninck, Ingeborg Dhooge, Ann Dierckx, Thomas Klenzner, Philipp Schörg, Georg Sprinzl, Freya Swinnen, Nicolas Verhaert, Annelies Vermeiren, Simone Volpert, Andrzej Zarowski, Arne Ernst

“…Methods: A prospective longitudinal study at 7 European tertiary referral centers was conducted including 19 SSD and 16 AHL subjects undergoing cochlear implantation. …”
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Detection of corrosion on silvered glass reflectors via image processing by Florian Wiesinger, Sarah Baghouil, Estelle Le Baron, Romain Collignon, Filipa Santos, Teresa C. Diamantino, Isabel Catarino, Jorge Facão, Cristina Ferreira, Soraia Páscoa, Florian Sutter, Aránzazu Fernández-García, Johannes Wette

“…The technique is developed by experts from different laboratories (OPAC, AGC, CEA and LNEG), which subsequently conduct two Round Robin experiments on corroded solar reflectors for validation. …”
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Sample Tracking Tool: A Comprehensive Approach Based on OpenArray Technology and R Scripting for Genomic Sample Monitoring by Giulia Trastulli, Giulia Calvino, Bruno Papasergi, Domenica Megalizzi, Cristina Peconi, Stefania Zampatti, Claudia Strafella, Carlo Caltagirone, Emiliano Giardina, Raffaella Cascella

“…Furthermore, its ability to accurately detect identical and different samples was evaluated through a simulation test conducted on an additional 100 samples. <b>Results</b>: In total, 55 probes achieved a call rate ≥90% and were subjected to the sample matching process performed by an R tool specifically developed. …”
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