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34001
Genome-wide identification of the bHLH gene family in Scutellaria baicalensis and their relationship with baicalin biosynthesis under drought stress
Published 2025-01-01“…Gene duplication events were analyzed, and cis-element analysis was conducted to explore regulatory factors. The expression patterns of these genes in different tissues and under drought stress were investigated using transcriptome data and qRT-PCR analysis. …”
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34002
Ultrasound May Suppress Tumor Growth, Inhibit Inflammation, and Establish Tolerogenesis by Remodeling Innatome via Pathways of ROS, Immune Checkpoints, Cytokines, and Trained Immun...
Published 2021-01-01“…We used microarray datasets from the NCBI GEO DataSet repository and conducted comprehensive data-mining analyses, where we examined the gene expression of 1376 innate immune regulators (innatome genes (IGs) in cells treated with LIUS. …”
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34003
Soybean and avocado unsaponifiables: a review of their potential use in the treatment of osteoarthritis
Published 2025-01-01“…The literature review was conducted manually through Pubmed, Scopus and Web of Science (WOS) databases, covering studies from 2000 to 2022 with terms like “osteoarthritis,” “OA,” “animal models,” “ASU,” and “soy/avocado.” …”
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34004
Effectiveness of purple leaves (Graptophyllum pictum L. Griff) and hydroxyapatite as socket preservation biomaterials
Published 2025-01-01“…The study groups were as follows: Group 1: Ad-MSCs; Group 2: Ad-MSCs + αmem; Group 3: Ad-MSCs + osteogenic medium + 1 % nano-extract of Purple leaves & Hydroxyapatite; Group 4: Ad-MSCs + osteogenic medium + 2 % nano-extract of Purple leaves & Hydroxyapatite. Observations were conducted on days 7, 14, and 21. Results: The combination of nanosuspension extract of Purple leaves and hydroxyapatite significantly increased the expression of RUNX2, OSX, OPN,ALP and calcium deposition compared to other groups. …”
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34005
Network-wide effects of pallidal deep brain stimulation normalised abnormal cerebellar cortical activity in the dystonic animal model
Published 2025-02-01“…This study explores how pallidal DBS alters spatiotemporal pattern formation of neuronal dynamics within the cerebellar cortex in a dystonic animal model, the dtsz hamster. Methods: We conducted in vitro analysis using a high-density microelectrode array (HD-MEA) in the cerebellar cortex. …”
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34006
Duplex qPCR for detecting and differentiating porcine epidemic diarrhea virus GI and GII subtypes
Published 2025-01-01“…PCR is the most commonly used technique for PEDV diagnosis in practical clinics, however, reported works still suffer from shortcomings, for example, most of them cannot differentiate GI and GII subtypes, they suffer from low sensitivity, and some primer sequences are no longer able to match the mutant strains.MethodsTo address these issues, we conducted a comprehensive analysis by comparing the sequences of the PEDV S protein in the existing NCBI database with a recently isolated epidemic strain of PEDV, named SX0818-2022, of subtype GIIa from Shanxi, China. …”
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34007
Dynamic analysis of growth characteristics, secondary metabolites accumulation, and an in-depth understanding of anthraquinones biosynthesis in Rubia cordifolia Linn.
Published 2025-01-01“…With the current depletion of natural resources of R. cordifolia, it is critical to conduct cultivation studies on the R. cordifolia. …”
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34008
Sitravatinib in combination with nivolumab plus ipilimumab in patients with advanced clear cell renal cell carcinoma: a phase 1 trial
Published 2025-01-01“…Abstract We conducted a phase I trial to determine the optimal dose of triplet therapy with the tyrosine kinase inhibitor sitravatinib plus nivolumab plus ipilimumab in 22 previously untreated patients with advanced clear cell renal cell carcinoma. …”
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34009
Clinical Research Network: JHCRN Infrastructure and Lessons Learned
Published 2025-01-01“…As of August 2024, total 81 studies‐clinical trials, cohort studies, and comparative effectiveness research have been conducted, with funding from the NIH, private foundations, and industry. …”
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34010
Multiorgan proteomic analysis of infected animal models predict potential host factors for chikungunya virus
Published 2025-01-01“…Abstract Chikungunya virus (CHIKV) is a mosquito‐borne alphavirus that is primarily known for causing severe joint and muscle symptoms, but its pathological effects have extended beyond these tissues. In this study, we conducted a comprehensive proteomic analysis across various organs in rodent and nonhuman primate models to investigate CHIKV's impact on organs beyond joints and muscles and to identify key host factors involved in its pathogenesis. …”
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34011
“We need workable micronutrient data!”: a qualitative study assessing the need for integrated micronutrient data to support evidence-based decisions by Indian food system stakehold...
Published 2025-01-01“…A qualitative, descriptive study was conducted, with purposive sampling of stakeholders from state and national-level government, development agencies, non-governmental organisations, research institutes, private organisations, and academia. …”
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34012
High expression of SULF1 is associated with adverse prognosis in breast cancer brain metastasis
Published 2025-01-01“…Further investigation related to SULF1 was conducted using online databases such as Kaplan–Meier Plotter and cBioPortal. …”
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34013
Incidence and pathological features of IgA nephropathy before and during the COVID-19 pandemic
Published 2025-02-01“…In this study, we analyzed kidney biopsy results from two medical institutions, covering the timeframe from January 2016 to May 2023. We conducted statistical analyses on various glomerular diseases according to their corresponding pathological diagnoses. …”
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34014
The Dutch-translated cultural competence assessment scale for nurses: Cross-cultural adaptation and validation
Published 2025-06-01“…We used a cross-sectional design and conducted the study in two phases. Nurses from all over the Netherlands were recruited through the newsletter of the Dutch nurses association and internal distribution by healthcare organisations. …”
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34015
Immunotargeting of Integrin αβ for Single-Photon Emission Computed Tomography and Near-Infrared Fluorescence Imaging in a Pancreatic Cancer Model
Published 2016-01-01“…After injection of 111 In-labeled probe to tumor-bearing mice, biodistribution, SPECT, autoradiography (ARG), and immunohistochemical (IHC) studies were conducted. After administration of ICG-labeled probe, in vivo and ex vivo NIR imaging and fluorescence microscopy of tumors were performed. …”
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34016
Evidence of Rehabilitative Impact of Progressive Resistance Training (PRT) Programs in Parkinson Disease: An Umbrella Review
Published 2020-01-01“…The PubMed, PEDro, Scopus, and Cochrane Library databases were searched from January 2009 to August 2019 for systematic reviews and meta-analyses conducted in English. The populations included had diagnoses of PD and consisted of males and females aged >18 years old. …”
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34017
Effects of repetitive thermal loads on microstructure and mechanical properties of potassium-doped tungsten alloy as plasma facing material
Published 2025-01-01“…Thermal load tests were conducted with a single-pulse duration of 1 s at absorbed power densities of 10, 13, 15 and 20 MW m ^−2 for 50 cycles at room temperature. …”
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34018
Naked-Eye Molecular Testing for the Detection of <i>Xylella fastidiosa</i> in Mallorca (Balearic Island) Almond Orchards by Colorimetric LAMP
Published 2025-01-01“…Following tissue homogenization, an alkaline treatment for target DNA extraction was conducted before the cLAMP test. The cLAMP assay was able to detect up to 100 CFU/mL of the <i>Xf</i> bacterial suspension diluted in healthy almond sap. …”
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34019
Diagnosis and management of de novo non-specific spinal infections: European Association of Neurosurgical Societies (EANS) Spine Section Delphi consensus recommendations
Published 2025-01-01“…Material and methods: A Delphi process was conducted with 26 experts from the European Association of Neurosurgical Societies (EANS). …”
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34020
Three-dimensional quantitative temporomandibular joint changes in skeletal class I malocclusion treated with extraction and non-extraction protocols: a comparative study of fixed o...
Published 2025-01-01“…Statistical analyses were conducted to compare the mean changes in intra- and inter-groups. …”
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