Upregulated GSDMB in Clear Cell Renal Cell Carcinoma Is Associated with Immune Infiltrates and Poor Prognosis by Yuanshan Cui, Zhongbao Zhou, Yumeng Chai, Yong Zhang

“…Functional enrichment analyses were conducted by utilizing the “ClusterProfiler” package. …”
Get full text

Identification of ubiquitination-related key biomarkers and immune infiltration in Crohn’s disease by bioinformatics analysis and machine learning by Wei Chen, Zeyan Xu, Haitao Sun, Wen Feng, Zhenhua Huang

“…Additionally, the correlation between key genes and immune infiltration was assessed, and Gene Set Enrichment Analysis (GSEA) of key genes was conducted. The efficacy of key genes was validated using ROC curves in an external dataset, and their expression was confirmed in LPS-induced Caco-2 cells through RT-qPCR. …”
Get full text

Tongue Muscle Training App for Middle-Aged and Older Adults Incorporating Flow-Based Gameplay: Design and Feasibility Pilot Study by Kuan-Chu Su, Ko-Chiu Wu, Kuei-Ru Chou, Chia-Hsu Huang

“…ResultsThrough exploratory factor analyses, a 2-factor (operation and immersion) structure was confirmed to have an adequate model fit (χ²36PP=PP ConclusionsOur research supports the further development of a gaming app to aid older adults with tongue muscle training and measure flow using physiological and psychological signals to enhance training accuracy and feasibility. Next, we aim to conduct a randomized pilot trial, improve app functions, offer alternative rehabilitation options, and encourage long-term participation. …”
Get full text

Relationship between physical activity and depressive symptoms in stroke survivors: a cross-sectional study of 1,140 individuals by Yihao Wang, Jiali Chen, Yanwei Zou, Mengshu Yang, Xiaoyun Kong, Ling Wang, Jingyuan Xue, Ci Dong

“…Patients: 1,140 stroke survivors from NHANES, assessing depressive symptoms through the Patient Health Questionnaire-9 (PHQ-9) conducted via family interview or a mobile examination centre examination. …”
Get full text

Inhibitory properties of a latent inhibitor after its compound preexposure with several novel stimuli: evidence from human conditioning by Unai Liberal, Gabriel Rodríguez, Paula Nogueiras, James Byron Nelson, Geoffrey Hall, Geoffrey Hall

“…To examine whether this phenomenon generalizes to humans, we conducted two experiments using a video game-based conditioning paradigm. …”
Get full text

Postoperative Outcomes in Prepectoral Versus Retropectoral Immediate Implant-based Breast Reconstruction Across Body Mass Index Categories by Gauthier Zinner, MS, Jérôme Martineau, MD, Giang Thanh Lam, MD, Daniel Correia, MS, Daniel F. Kalbermatten, MD, PhD, Carlo M. Oranges, MD, PhD

“…A monocentric retrospective analysis was conducted on patients who underwent mastectomy and IBBR from January 2018 to December 2023. …”
Get full text

Career Motivation in the Process of State Regulation of Youth Employment by Natalya Stativka, Anna Batiuk

“…A vast majority of research works on professional motivation and career development were conducted by scientists from the fields of pedagogy, psychology and social economy. …”
Get full text

Application of rock phosphate enriched composts increases nodulation, growth and yield of chickpea by Allah Ditta, Juma Muhammad, Muhammad Imtiaz, Sajid Mehmood, Zheng Qian, Shuxin Tu

“…Methods To investigate the effect of different combinations of RP and compost (0:100, 25:75, 50:50, 75:25 and 100:0) and time of application (30, 15, 7, 3 and 0 days before sowing), each was conducted in two consecutive pot experiments while, the rate of application (100–1000 kg ha−1) was investigated under field conditions, in comparison to control (recommended P fertilizer). …”
Get full text

A case report: interstitial pneumonia following treatment of gastric cancer with sintilimab in combination with S-1 by Pei Zhu, Qingming Sun, Sheng Xu, Wanhui Dong

“…The treatment was discontinued, and after receiving adequate glucocorticoid therapy, the pulmonary lesions showed slight improvement.ConclusionThis case provides a clinical reference, indicating that prior touse of sintilimab in combination with S-1 antitumor regimen, a comprehensive baseline assessment should be conducted, including blood routine examination, enzyme tests, and pulmonary imaging examination, with close monitoring of the patient’s pulmonary condition. …”
Get full text

Expression of some circulating microRNAs as predictive biomarkers for prognosis and treatment response in glioblastoma by Elham Ali, Marwa Adel Ahmed, May A. Shawki, Lobna R. Ezz El Arab, Mohamed K. Khalifa, Menha Swellam

“…This study investigated how miR-29a, miR-106a, and miR-200a affect the prognosis of GBM patients. This study was conducted on 25 GBM patients and 20 healthy volunteers as a control group. …”
Get full text

Adsorption characteristics of metronidazole on CoZr-LDH and its GO nanocomposite: Experimental and theoretical study by Edris Jamshidi, Fateme Fathabadi, Faranak Manteghi, Rahime Eshaghimalekshah

“…This study emphasizes the potential of GO-enhanced CoZr-LDH for effective removal of metronidazole, addressing its status as a critical pollutant in wastewater.To comprehensively study the adsorption process in CoZr-LDH and CoZr-LDH/GO, theoretical analyses were conducted using Monte Carlo computational method. This approach, known for simulating numerous particle trajectories and statistical averaging, allowed for an in-depth examination of adsorption mechanisms under various conditions. …”
Get full text

Development of a brief screening measure of unmet supportive care needs (SCNS-P&C-6) in caregivers of people with high-grade glioma by Jill Chen, Joanne M. Shaw, Haryana M. Dhillon, Georgia K. B. Halkett, Emma McDougall, Anna K. Nowak, Rachel Campbell, for the BRAINs Program Investigators

“…Supplementary analysis was conducted at two timepoints (T1 & T2) on the final selected items to identify caregivers indicating no needs on the screening items but reported a need on the original SCNS-P&C, suggesting they would be “missed” by the screening items. …”
Get full text

Characteristics and outcomes of secondary acute lymphoblastic leukemia (sALL) after multiple myeloma (MM): SEER data analysis in a single-center institution by Jing Jia, Jiahui Yin, Chuanying Geng, Aijun Liu

“…This study aimed to elucidate the clinical features and outcomes of patients with sALL after MM. Methods: We conducted this population-based study using the Surveillance, Epidemiology, and End Results (SEER) database and retrospectively reviewed patients with sALL following MM treatment at our institution. …”
Get full text

Development and application of a dietary program to reduce sugar intake using a living lab approach in Korea: an intervention study by Jung-Hyun Kim, Min Sook Kyung, Seul Ki Choi

“…The dietary program was conducted in two phases; start and next levels. The start level included a pre-assessment of dietary behaviors and participation in educational platforms, whereas the next level included activities using educational platforms, tailored mission and feedback, and pre- and post-surveys. …”
Get full text

PENGEMBANGAN INSTRUMEN TES KETERAMPILAN PEMECAHAN MASALAH PADA KONSEP USAHA DAN ENERGI DI SMA by Putri Eka Lestari, Andik Purwanto, Indra Sakti

“…Kata Kunci: Instrumen tes, Keterampilan Pemecahan Masalah, Usaha (Kerja) dan Energi  ABSTRACT  This research was aimed to develop test instrument that was valid and reliable for student problem solving skills on the concept of work and energy. This research was conducted with a 4D development model which consisted of define, design, develop, and disseminate. …”
Get full text

Roles of Service Quality and Religiosity in Determining Customers’ Retention in Islamic Banks: Empirical Evidence from Southwestern Afghanistan by Ziarmal Abdullah, Salina Kassim, Shamsullah Shams, Sharofiddin Ashurov

“…It would be good to perform these studies because they are conducted similarly in other nations (such as the ASEAN countries). …”
Get full text

Influencing Factors of Resorption in Lumbar Disc Herniation by SHEN Xueqiang, LIU Jintao, YU Pengfei, DAI feng, ZHU Yu, JIANG Hong

“…Univariate analysis was conducted to find the indicators with statistical differences between the two groups, which were further analyzed by logistic regression to determine whether they were independent factors affecting the resorption of LDH.ResultsThe symptoms of 45 patients with resorption significantly improved, and of the 71 patients without resorption, 23 patients underwent surgery. …”
Get full text

Trends in Clinico-radiological and Laboratory Characteristics of All-Cause Meningoencephalitis in Western Rajasthan by Ravi Krishna Kanth, Samhita Panda, Sarbesh Tiwari, Taruna Yadav, Gopal Krishana Bohra, Ravi Shekar Gadepalli

“…Methods: This prospective, observational, and descriptive study was conducted from July 2021 to March 2023. Patients satisfying the case definition of “meningitis” and “encephalitis” were enrolled. …”
Get full text

PEDF Overexpression Ameliorates Cardiac Lipotoxicity in Diabetic Cardiomyopathy via Regulation of Energy Metabolism by Mao T, Wang Y

“…At week 24, assessments were conducted on cardiac hypertrophy, fibrosis, cardiac function, and alterations in energy metabolism. …”
Get full text

Comparative Analysis of Virology and Pathogenesis of SARS-CoV-2 and HIV Infections: Implications for Public Health and Treatment Strategies by Olebo DF, Igwe MC

“…Understanding their differences can enhance public health strategies and treatment approaches.Purpose: This narrative review compares the virology, transmission, immune responses, and clinical outcomes of SARS-CoV-2 and HIV to inform treatment strategies and public health interventions.Methods: A narrative review was conducted, synthesizing data from peer-reviewed literature and expert commentary from 2010 to 2024. …”
Get full text