Understanding barriers and facilitators to non-pharmaceutical chronic pain research engagement among people living with chronic pain in the UK: a two-phase mixed-methods approach by Daniel Baker, Kirralise Hansford, Anna E Crossland, Catherine Preston, Kirsten J McKenzie

“…The greatest facilitator identified was ‘improved accessibility’, which related to the accessibility of the research environment, the type of research being conducted and accessible advertisement of the research within trusted settings. …”
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Clinical trials since 2020 of rapid anti-suicidal ideation effects of ketamine and its enantiomers: a systematic review by Sumra Sajid, J. John Mann, Michael F. Grunebaum

“…Abstract Background Suicide is a global public health problem with few empirically supported treatments. Methods We conducted a systematic review of clinical trials (CT) since 2020 of racemic ketamine or one of its enantiomers’ (R/S) potential to reduce suicidal ideation or behavior (SIB). …”
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Exploring the Causal Relationship and Molecular Mechanisms Between Fasting Insulin and Androgenetic Alopecia: A Mendelian Randomization Study with Bioinformatics Analysis by Ding X, Bai Z, Wang W, Gu Y, Li Z, Fan Y

“…In this study, a Mendelian randomization (MR) analysis was utilized to discover the causal associations between FI and AGA.Methods: Genome-wide association study (GWAS) data for FI and AGA were retrieved, and bidirectional MR analysis was conducted. FI-associated genes were identified through expression quantitative trait loci (eQTL) analysis, with enrichment analysis and a protein-protein interaction (PPI) network used to explore potential pathways and core genes.Results: Forward MR analysis revealed a significant causal relationship between elevated FI levels and AGA (P=0.027, OR=43.944). …”
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Frameshift variation in the HMG-CoA reductase gene and unresponsiveness to cholesterol-lowering drugs in type 2 diabetes mellitus patients by Esmat Khaleqsefat, Khder Hussein Rasul, Ramiar Kamal Kheder, Sonia Baban, Jamil Baban

“…Biochemical tests were conducted, followed by genetic analysis to identify mutations in the HMGCR gene. …”
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Aedes-borne arboviral human infections in Europe from 2000 to 2023: A systematic review and meta-analysis by Nadja Hedrich, Maria Bekker-Nielsen Dunbar, Martin P. Grobusch, Patricia Schlagenhauf

“…Methods: This systematic review was conducted in accordance with PRISMA guidelines and registered in Prospero (CRD42023360259). …”
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London Rocket (<i>Sisymbrium irio</i> L.) as Healthy Green: Bioactive Compounds and Bioactivity of Plants Grown in Wild and Controlled Environments by Tarik Chileh-Chelh, Tatiana Pagan Loeiro da Cunha-Chiamolera, Miguel Urrestarazu, Mohamed Ezzaitouni, Rosalía López-Ruiz, Cinthia Nájera, Miguel Ángel Rincón-Cervera, José Luis Guil-Guerrero

“…In this study, we analyzed the leaves of wild <i>S. irio</i> plants and those grown in controlled environments (GCE) with varying electrical conductivities (EC) and light spectra. Plants were assessed for growth, phenolic content, vitamin C, antioxidant activity, glucosinolates, and antiproliferative effects against HT-29 human colorectal cancer cells. …”
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Cytomorphology, osmotic fragility, glucose-6-phosphate dehydrogenase and oxidant/antioxidant status in postparturient haemoglobinuria in dairy cattle and buffaloes by A. I. Hassanin, M. H. Karam, N.-E. M. Aref

“…Complete history and clinical examination were conducted. Blood samples were collected and prepared accordingly to assess complete blood count (CBC), reticulocyte count, cytomorphology of RBCs, osmotic fragility, erythrocytic G6PD, GSH-Px, blood phosphorus (P), calcium (Ca), para-thormone (PTH), MDA and NO. …”

Ensemble machine learning models for lung cancer incidence risk prediction in the elderly: a retrospective longitudinal study by Songjing Chen, Sizhu Wu

“…Proposed method could also be used in predicting the risk of other chronic diseases to help conduct intervention and reduce incidence.…”
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Macroinvertebrates composition as determinants of larval abundance in the dragonfly Miathyria marcella in tropical wetlands by M.I. Moreno Pallares, M.A. Bonilla Gómez, G.H. Guillot Monroy, A.C. Torregroza-Espinosa

“…In addition, a correlation analysis was conducted between macroinvertebrate composition and Miathyria  marcella larval abundance.FINDINGS: A total of 2586 larvae, and 12925 individual macroinvertebrates were collected, distributed in 25 orders and 58 families. …”
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Patient-Centric Structural Determinants of Adherence Rates Among Asthma Populations: Exploring the Potential of Patient Activation and Encouragement Tool TRUSTR to Improve Adherenc... by Asim Zia, Arthur Brassart, Sheila Thomas, Fen Ye, Judith J. Stephenson, C. Daniel Mullins, Christopher A. Jones

“…Fourteen additional SEMs were estimated to lateralize TRUSTR findings and conduct sensitivity analysis. **Results:** HIRD data reveal mean adherence rate of 59% (standard deviation (SD) 29%) for PDC and 58% for MPR (SD 36%). …”
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Comparative Study on Recovery and Post-Operative Analgesic Efficacy from Fentanyl- Versus Dexmedetomidine-Based Anesthesia in Head and Neck Cancer Surgery by Liza Mohanty, Ravi Kumar, Deepak Tugave, Anagha Agrawal, Sejal Patel, Monika Tanwar, Lalit Patil

“…Materials and Methods: A randomized controlled trial was conducted with 120 patients undergoing head and neck cancer surgery. …”
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Perspectives of push-pull-mooring effects on a desire for switching to alternative crops among tobacco farmers in Thailand: A qualitative study by Chakkraphan Phetphum, Artittaya Wangwonsin, Atchara Prajongjeep, Saksin Simsin

“…Methods Semi-structured interviews were conducted with 34 tobacco farmers expressing a desire to transition to other crops in two communities in Thailand. …”
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Machine learning-based interpretation of non-contrast feature tracking strain analysis and T1/T2 mapping for assessing myocardial viability by Amir GhaffariJolfayi, Alireza Salmanipour, Kiyan Heshmat-Ghahdarijani, MohammadHossein MozafaryBazargany, Amir Azimi, Pirouz Pirouzi, Ali Mohammadzadeh

“…A retrospective analysis was conducted on 79 patients with myocardial infarction (MI) 2–4 weeks post-event. …”
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Lived experiences and perspectives of women who had undergone perinatal loss in Nairobi county, Kenya: a qualitative study by Emily Wanja Kaburu, Christopher O Aimakhu, Thomas Matenjwa Kamau, Michael Omondi Owor

“…This study aimed to shed light on the experiences of bereaved women to come up with effective interventions and combat the stigma associated with perinatal loss.Methods The study used a qualitative research design employing a descriptive phenomenological approach targeting women of reproductive age who had experienced perinatal loss within the previous 3 years. The study was conducted in three subcounties of Nairobi. Purposive sampling was used to identify and recruit 22 women to participate in focus group discussions. …”
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Predictors of frequency of CF care in the US Cystic Fibrosis Foundation Patient Registry. by Alexandra C Hinton, Edmund H Sears, Jonathan B Zuckerman, Sara Lopez-Pintado

“…<h4>Objective</h4>To determine sociodemographic and disease-related factors predictive of visit frequency in pwCF and to assess how these effects vary across the lifespan.<h4>Methods</h4>We conducted an observational cohort study using data from 2004-2016 for pwCF aged 6-60 years in the US Cystic Fibrosis Foundation Patient Registry. …”
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Survival status and determinants of under-five mortality in Sudan: Evidence from the Multiple Indicator Cluster Survey 2014 by Huda Mohamed Mukhtar AHMED, Hiba Abbas Omer ELKARIB, Mutaz Fikri Mohamed Osman DIGNA

“…Methods: Data by the Multiple Indicator Cluster Survey conducted in 2014 by the Central Bureau of Statistics (CBS) and the Federal Ministry of Health, Sudan, were collected. …”
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Mme de Graffigny and the Archduchess: Indirect Correspondence between the Court and 'le monde' by Kelsey Rubin-Detlev

“…This essay examines two very different three-way correspondences in which private letters operate in a semi-public sphere and in which the relationship between private conduct and public image is at stake. Both involve the daughters of Maria Theresa of Austria (1717–1780): first, the epistolary triangle formed by the prominent French writer Mme de Graffigny, her friend Mme Copineau and Archduchess Maria Elisabeth; and, second, that of Maria Theresa, the dauphine and then queen of France Marie-Antoinette, and the Austrian ambassador to Paris, Florimond Claude, comte de Mercy-Argenteau. …”
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Unveiling user identity across social media: a novel unsupervised gradient semantic model for accurate and efficient user alignment by Yongqiang Peng, Xiaoliang Chen, Duoqian Miao, Xiaolin Qin, Xu Gu, Peng Lu

“…Extensive experiments conducted on four pairs of real datasets demonstrate the superiority of our approach. …”
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AI predicting recurrence in non-muscle-invasive bladder cancer: systematic review with study strengths and weaknesses by Saram Abbas, Rishad Shafik, Naeem Soomro, Rakesh Heer, Rakesh Heer, Kabita Adhikari

“…A systematic literature search was conducted, focusing on the statistical robustness and algorithmic efficacy of studies. …”
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Experience, access and utilisation of fertility care for infertile men within the biomedical sector in urban Bangladesh: protocol for a qualitative study by Papreen Nahar, Gitau Mburu, Sohana Shafique, Priya Satalkar-Götz, Foyjunnaher Sultana

“…This study aims to provide insights into the lived experience of male infertility, the availability and access of infertility services for men within the biomedical sector in Bangladesh and the potential willingness of men to use home-based semen testing.Methods and analysis This qualitative study will be conducted in Dhaka and Khulna districts in Bangladesh over 18 months (late 2023–2025). …”
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