Fragment optimized chalcone derivatives targeting OmpA protein as a therapeutic approach against multidrug resistant Acinetobacter baumannii by Muhammad Naveed, Amina Abid, Tariq Aziz, Ayesha Saleem, Arooj Arshad, Khushbakht Javed, Hafiz Muzzammel Rehman, Ghulam Nabi, Mitub Al-harbi, Abdullah F. Alasmari

“…Additionally, ADMET (absorption, distribution, metabolism, excretion, and toxicity) analysis was conducted to assess the pharmacokinetic properties of the compounds. …”
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The effectiveness of ERCP in managing preoperative complications of choledochal cysts in children and its role in facilitating early surgical intervention by Tian Zhang, Wenjie Wu, Yijun Shu, Hao Weng, Mingzhe Weng, Ying Zhou, Xuefeng Wang

“…This study aimed to investigate the safety and effectiveness of ERCP in managing preoperative complications of choledochal cyst in children, as well as the timing for definitive surgery following ERCP.MethodsWe conducted a retrospective review of medical records for 68 pediatric patients who presented with complications of choledochal cyst, including pancreatitis and biliary obstruction combined with cholangitis. …”
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Prospectiva del desarrollo local. Caso: Sistema de Riego El Cenizo, Estado Trujillo, Venezuela by Ligia Nathalie García Lobo

“…The design was framed on an experimental design, through field research. It was conducted by a non-probability sampling rate to 35-intentioned owners or managers of SMEs at Táchira. …”
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Etiology, Risk Factors, and Antimicrobial Resistance in Recurrent Pyogenic Liver Abscesses: A Six-Year Analysis by Cui J, Liu Y, Fu H, Cui M, Li J, Bai Z, Li J

“…JinHua Cui,1 YaMan Liu,2 Hua Fu,1 MiaoHang Cui,1 JiZhong Li,3 ZiYu Bai,1 Jian Li1 1Department of Hepatobiliary Surgery, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, People’s Republic of China; 2Department of Gynaecology, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, People’s Republic of China; 3Department of Operating Room, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, People’s Republic of ChinaCorrespondence: Jian Li, Department of Hepatobiliary Surgery, Affiliated Hospital of Chengde Medical College, Chengde City, Hebei Province, People’s Republic of China, Email lijian111008@126.comAim: To perform a comparative analysis of the clinical data of patients with and without recurrent pyogenic liver abscess and explore the influencing factors, clinical characteristics, and pathogenic bacteria associated with the recurrence of liver abscesses.Patients and Methods: A retrospective analysis was conducted on 436 recently diagnosed patients with pyogenic liver abscess admitted to the Affiliated Hospital of Chengde Medical College between June 2017 and June 2023. …”
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Acceptability of telemedicine for early surgical site infection diagnosis after cesarean delivery in rural Rwanda: a qualitative study by Laban Bikorimana, Eve Hiyori Estrada, Anne Niyigena, Robert Riviello, Fredrick Kateera, Bethany Hedt-Gauthier, Vincent K. Cubaka

“…As the study timeline coincided with the beginning of the COVID-19 pandemic we additionally asked about their perceptions of telemedicine in this context . Methods We conducted qualitative, semi-structured in-depth interviews in Kinyarwanda among 26 individuals (14 women and 12 CHWs) who participated in the telemedicine intervention. …”
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Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways by Randa Ismail, Heba A. Habib, Aliaa F. Anter, Amr Amin, Gehan H. Heeba

“…Its potential liver and lung toxicity often limits its clinical effectiveness. We conducted this study to demonstrate the possible protective impacts of a natural galectin-3 (Gal-3) inhibitor, modified citrus pectin (MCP), against MTX-induced liver and lung toxicity and verify the potential signaling pathways of these suggested effects. …”
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Determinants of Neural Tube Defects among Newborns in Amhara Region, Ethiopia: A Case-Control Study by Abay Woday Tadesse, Ayesheshim Muluneh Kassa, Setognal Birara Aychiluhm

“…A case-control study design was conducted among 400 newborns (133 cases and 267 controls) who were born at randomly selected public hospitals. …”
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Challenges in Exercising the Right to Appeal – The Case of Slovenian Administrative Consultation by Polonca Kovač

“…For this purpose, an analysis of Administrative Consultation (AC), a legal clinic operating since 2009, was conducted. The study includes analyses of the content, complexity, and reasoning behind the occurring dilemmas as a ground for GAPA recodification. …”
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Undernutrition and Associated Factors among Under-Five Orphan Children in Addis Ababa, Ethiopia, 2020: A Cross-Sectional Study by Selam Shegaw Sewnet, Hunegnaw Almaw Derseh, Hanna Demelash Desyibelew, Netsanet Fentahun

“…An institution-based cross-sectional study was conducted in Addis Ababa from February 28 to March 28, 2020. …”
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The Effect of an Educational Application on The Quality of Life and Treatment Adherence in Mothers of Children with Congenital Heart Disease Undergoing Cardiac Surgery: A Randomize... by Mohammad Rajabi, Jamalodin Begjani, Reza Negarandeh

“…This study evaluated the impact of a mobile educational application on the QoL and TA in mothers of children with CHD undergoing cardiac surgery.Methods: This randomized clinical trial was conducted on 72 mothers of children with CHD referred for cardiac surgery to Children’s Medical Center Hospital, Tehran, Iran, from September 2023 to May 2024. …”
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Non-pharmacological interventions for the prevention of type 2 diabetes in low-income and middle-income countries: a systematic review of randomised controlled trials by K M Saif-Ur-Rahman, Md Shariful Islam, Anupam Sarker, Rina Das, Saraban Ether

“…The secondary outcome is to measure changes in glycated haemoglobin (HbA1c) level, weight/body mass index (BMI), fasting glucose level and 2-hour glucose from baseline of the included randomised controlled trials.Methods This review has been conducted following the standard systematic review guidelines. …”
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Evaluating body roundness index and systemic immune inflammation index for mortality prediction in MAFLD patients by Di Zeng, Qingyue Zeng, Shuangqing Li, Jiong Lu, Nansheng Cheng

“…A nationwide retrospective cohort study was conducted using data from the NHANES database (January 1999–December 2018), including patients diagnosed with MAFLD. …”
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The design of paper-based electroanalytical microfluidic device coupled with post-synthesized molecularly imprinted polymers (rGO/Au@Ag2S/PANI/polyacrylamide) for the detection of... by Mina Adampourezare, Karim Asadpour-Zeynali, Miguel de la Guardia, Jafar Ezzati Nazhad Dolatabadi

“…The fabricated device showed high sensitivity toward streptomycin, which was due to synergistic effects between catalytic properties, electrical conductivity of rGO/Au@Ag2S/anline /Polyacrylamide, and considerably increased numbers of imprinted sites. …”
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Impact of hospital readiness on patient safety incidents during the COVID-19 pandemic in Indonesia: health worker perceptions by Inge Dhamanti, Diah Indriani, Muhammad Miftahussurur, Eva Kurniawati, Cyrus Y Engineer

“…Objectives This study examined the impact of hospital readiness on patient safety from the healthcare workers’ perspective.Design The study employed a mixed-methods explanatory sequential design, with the quantitative phase taking precedence. We conducted an online survey of 235 healthcare workers at COVID-19 referral hospitals, followed by an interview with 11 participants from various hospital types.Setting COVID-19 referral hospitals in Indonesia.Participants Health workers working at COVID-19 referral hospitals.Measures Hospital ownership; hospital accreditation status; hospital readiness including incident management system, surge capacity, infection control and prevention, and human resource management; patient safety incident.Results According to the survey, 66.4% of the participants worked at a hospital owned by the provincial or district government, and 69.4% worked at a hospital which had received an excellent status accreditation. …”
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Validation and assessment of the arabic psychological first aid scale among physicians, nurses, and counselors in Jordan by Basma Eid Alshareef, Othman A. Alfuqaha, Ibraheem B. Maali, Khaled Amer

“…Descriptive, translation, validation process, and reliability were conducted. Results The translation process was satisfied. …”
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Vascularized composite allograft deceased donation in the United States by Wida S. Cherikh, Samantha M. Noreen, Alexandra Lewis, Sarah E. Booker, Jesse Howell, Erin M. Schnellinger, Jennifer L. Wainright, Christopher C. Curran

“…As the field continues to evolve and more data becomes available, further analyses need to be conducted to understand the demographics of VCA donors and the potential impact of VCA donation within the donation and transplant system.…”
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PROMISE: Prognostic Radiomic Outcome Measurement in Acute Subdural Hematoma Evacuation Post-Craniotomy by Alexandru Guranda, Antonia Richter, Johannes Wach, Erdem Güresir, Martin Vychopen

“…Initial scans were performed within 24 h of trauma, followed by routine postoperative scans to assess residual hematoma. We conducted radiomic analysis of preoperative and postoperative volumes, surface area, Feret diameter, sphericity, flatness, and elongation. …”
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Mechanical Strain-Mediated Tenogenic Differentiation of Mesenchymal Stromal Cells Is Regulated through Epithelial Sodium Channels by Hui Yin Nam, Malliga Raman Murali, Raja Elina Ahmad, Belinda Pingguan-Murphy, Hanumantha Rao Balaji Raghavendran, Tunku Kamarul

“…The present study was thus conducted to investigate the role of ENaC in human bone marrow-derived MSCs (hMSCs) tenogenic differentiation during uniaxial tensile loading. …”
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The relationship of body mass index with fasting blood glucose in type-2 diabetes mellitus by Rimadhani Ervina Tria, Mawardi Fitriana, Dewi Fitria Puspita, Purwanta Barkah Djaka, Sholikah Amanatus, Hutomo Muhammad Agita

“…Therefore, this research was conducted to investigate the relationship between body mass index (BMI) and fasting blood sugar (FBG) levels in type 2 diabetes patients at Umbulharjo 1 Public Health Center, Yogyakarta Province. …”
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Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy by Christopher R. Starr, Assylbek Zhylkibayev, Oleg Gorbatyuk, Alli M. Nuotio-Antar, James Mobley, Maria B. Grant, Marina Gorbatyuk

“…Glucose-sensing ChREBP and MondoA are transcriptional factors involved in the lipogenic, inflammatory, and insulin signaling pathways implicated in metabolic disorders; however, limited ocular studies have been conducted on these proteins. We aimed to investigate the potential role of ChREBP in the pathogenesis of diabetic retinopathy (DR). …”
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