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  1. 31161

    Analysis of the efficacy of MALDI-TOF MS technology in identifying microorganisms in cancer patients and oncology hospital environment by Grażyna Czeszewska-Rosiak, Iwona Adamczyk, Agnieszka Ludwiczak, Piotr Fijałkowski, Paweł Fijałkowski, Magdalena Twarużek, Michał Złoch, Dorota Gabryś, Wioletta Miśta, Andrzej Tretyn, Paweł Piotr Pomastowski

    Published 2025-01-01
    “…Rapid diagnostics of microbes in hospitals are crucial for promptly identifying infections, enabling timely and appropriate treatment. The study was conducted to evaluate the effectiveness of the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI TOF MS) technology in the microbial profiling of hospital environments and patient samples. …”
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  2. 31162
  3. 31163
  4. 31164
  5. 31165

    Novel (Q)SAR models for prediction of reversible and time-dependent inhibition of cytochrome P450 enzymes by Sadegh Faramarzi, Arianna Bassan, Kevin P. Cross, Xinning Yang, Glenn J. Myatt, Donna A. Volpe, Lidiya Stavitskaya

    Published 2025-02-01
    “…The 2020 FDA drug-drug interaction (DDI) guidance includes a consideration for metabolites with structural alerts for potential mechanism-based inhibition (MBI) and describes how this information may be used to determine whether in vitro studies need to be conducted to evaluate the inhibitory potential of a metabolite on CYP enzymes. …”
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  6. 31166

    DIGITAL INFORMATION’S INFLUENCE ON FORMING TOURISM EVENT IMPRESSIONS: THE INTERPLAY OF GENDER AND TOURISM TYPES by Amany E. SALEM, Thowayeb H. HASSAN, Mahmoud I. SALEH, Mostafa A. HASSANIN, Hassan Marzok Elsayed MAHMOUD, Ashraf Mohamed ANAS, Hadeel Sa'ad AL-HYARI, Hisham Mohammad AL-SMADI, Yasmine E. HAMZA

    Published 2024-09-01
    “…This study explores how perceptions of digital information vary across different tourism experience types (adventure, leisure, cultural) and examines the complex interactions between digital information perception and tourism engagement. A survey was conducted among tourists actively participating in various tourism types to collect data on their digital information consumption habits and their influence on their overall perceptions. …”
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  7. 31167

    The SGLT-2 Inhibitors and their Role in the Treatment of Heart Failure - A Review of Literature by Silvia Ciraolo, Agnieszka Kulczycka-Rowicka, Joanna Wojda, Katarzyna Lesiczka-Fedoryj, Anna Walczak, Zuzanna Kościuszko, Adam Sobiński, Matylda Czerwonka, Katarzyna Kurza, Julianna Podolec

    Published 2025-02-01
    “… • Research materials and methods: A comprehensive literature review was conducted, analyzing clinical trials, guideline documents, and mechanistic studies on SGLT2 inhibitors. …”
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  8. 31168

    The interplay between persistent pathogen infections with tumor microenvironment and immunotherapy in cancer by Si Chen, Caihong Yao, Na Tian, Chunying Zhang, Yuemei Chen, Xuting Wang, Yue Jiang, Tonghao Zhang, Tingting Zeng, Yali Song

    Published 2024-09-01
    “…Additionally, it seeks to investigate the effects of these infections on specific immune checkpoints and identify potential targets for immunotherapy. Methods We conducted searches, readings, and detailed analyses of key terms in databases like PubMed and Web of Science to evaluate the impact of chronic infections by pathogenic microorganisms on the immune microenvironment. …”
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  9. 31169

    Association between bacterial presence in urinalysis and hypertension during pregnancy in women at Margono Hospital, Purwokerto: A single-center study in Indonesia by Dina Marlina, Aditya Utomo, Putri Nadhira Adinda Adriansyah, Herman Sumawan, Budi Handono, Muhammad Alamsyah Aziz

    Published 2025-01-01
    “…Methods: This study was conducted at Margono Hospital, Indonesia; the study included all pregnant women who delivered in 2022–2023, applying specific exclusion criteria. …”
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  10. 31170

    A MULTICENTER STUDY OF BENIGN PROSTATIC HYPERPLASIA PATIENTS UNDERGOING TRANSURETHRAL RESECTION OF THE PROSTATE IN INDONESIA: A DESCRIPTIVE ANALYSIS by Besut Daryanto, Kurnia Penta Seputra, Paksi Satyagraha, Taufiq Nur Budaya, Fauzan Kurniawan Dhani, Deddy Rasyidan Yulizar, Marta Hendry, Andrie Rhomdhon, Yudi Ambeng, Ryan Akhmad Adhi

    Published 2025-01-01
    “…Material & Methods: This study is a descriptive cross-sectional study conducted at four provinces  in Indonesia. Patient data were collected from January 2021 to December 2023, including all patients diagnosed with BPH and who underwent TURP. …”
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  11. 31171

    Bicyclic peptide-enhanced covalent inhibitor of SARS-CoV-2 3CL protease by Qian Wang, Yanhui Wang, Jian Li, Hong Liu, Shiyu Chen

    Published 2024-10-01
    “…Medicinal chemistry optimization was conducted to improve the potency of these peptides. …”
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  12. 31172

    Similarities and differences in physiological adaptation to cadmium interactions with nitrogen levels between two aquatic iris life forms in urban wetlands by Zhenzuo Lei, Yuan Jiang, Yanqiong Meng, Yiyong Li, Yucong Li, Tao Hu, Yanjun Ma

    Published 2025-01-01
    “…In this study, pot experiments were conducted to investigate the effects of nitrogen (N) on the adaptation strategies of two evergreen and deciduous aquatic iris life forms under cadmium (Cd) stress. …”
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  13. 31173

    Impacts of different pig slurry application methods on soil quality indicators in a maize-soybean cropping sequence in the Sub-humid Pampas of Argentina by Vanesa Pegoraro, Cristian Cazorla, Omar Bachmeier, Tomás Baigorria, Mónica Boccolini, Jimena Ortiz, Claudio Lorenzon, Susana Hang, Marta Zubillaga

    Published 2020-09-01
    “…Treatments with PS and/or FM showed lower values in pH than C in both crops, and higher electrical conductivity only in maize. SS treatment showed higher Pe on soybean, indicating a maintenance of the P levels with respect to those in MF and C. …”
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  14. 31174

    Protective effects of resveratrol and naringenin against nonylphenol-induced oxidative stress in rats by Haitham S. Elewa, Dawlat A. Salama, Mohamed S. Hikal, Mohamed F. Abd El hamid, Mohamed H. Eid, Fatma M. A. Khalil, Muayad S. Albadrani, Khaled Abdelaal, Ahmed I. El-Tokhy

    Published 2025-01-01
    “…Resveratrol (RES) and Naringenin (NG) are phytochemicals possessing antioxidant properties and estrogenic activity. This study was conducted to investigate the toxicity of NP and the mitigating effects of RES and NG on NP toxicity in rats. …”
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  15. 31175
  16. 31176

    Practical Implications in Contemporary Dental Aesthetics—Shade Selection Assessment Using Intraoral Scanners by Alice Arina Ciocan Pendefunda, Cristina Gena Dascalu, Sebastian Bahrim, Cristina Iordache, Odette Luca, Magda-Ecaterina Antohe

    Published 2025-01-01
    “…The purpose of the study is to assess the accuracy of the shade selection feature of intraoral scanners (CEREC Omnican, 3Shape TRIOS) in comparison with an already established method—the VITA Easyshade V spectrophotometer (VE)—and test if there is any significant difference between the three devices. <b>Methods:</b> To conduct this in vitro study, the VITA Classical shade guide was used. …”
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  17. 31177

    Effect of ectoparasite Ichthyophthirius multifiliis on the histopathology and gill and gut microbiota of goldfish (Carassius auratus) by Xialian Bu, Xialian Bu, Xianqi Peng, Xianqi Peng, Lei Huang, Lei Huang, Yu Zhao, Jinbiao Jiao, Jinbiao Jiao, Jian Zhu, Jing Chen, Jing Chen, Xiaohong Huang, Xiaohong Huang, Aqin Zheng, Aqin Zheng, Huantao Qu, Jiayun Yao, Jiayun Yao

    Published 2025-02-01
    “…Meanwhile, 16S rRNA gene amplicon sequencing was conducted to analyze the difference of gill and gut microbiota between I. multifiliis-infected and uninfected goldfish.ResultsHistopathological examination revealed that I. multifiliis has induced significant damage to the gills of goldfish, characterized by lamellae fusion, cell hyperplasia, cell hyperaemia, inflammatory infiltration, necrosis and desquamation. 16S rRNA gene sequencing result showed that alpha and beta diversity of gill microbiota was significantly reduced in the I. multifiliis-infected group, while no significant changes were observed in gut microbiota. …”
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  18. 31178

    Experimental research on remote non-contact laser vibration measurement for tunnel lining cavities by Hongyun Yang, Yu Xie, Zhi Lin, Lin Li, Xiang Chen, Wanlin Feng, Honglin Ran, Li He

    Published 2025-01-01
    “…In this study, concrete slabs with different parameter cavities were selected as the research object, and experiments on remote detection using Laser Doppler Vibrometry were conducted. During the experiments, the vibration parameters of the concrete surface were measured for cavities of varying sizes and depths, filled with different materials, and under different detection distance conditions. …”
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  19. 31179
  20. 31180

    Long-Term efficacy and safety analysis of secukinumab in the treatment of pediatric generalized pustular psoriasis: a real-world study by Lu Xing, Lingsheng Long, Tao Wu, Lingrui Yin, Li Yu, Jingnan Wu, Danchen Li, Limin Miao, Hong Shu

    Published 2025-12-01
    “…Purpose: To evaluate the long-term efficacy and safety of secukinumab in pediatric patients with generalized pustular psoriasis (GPP).Materials and methods: A retrospective study was conducted from July 2021 to July 2024, including 10 children with GPP. …”
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