Decentralized clinical trials are better for the participants and for the planet: the case study of a double-blind randomized controlled trial in Singapore (PROMOTE study) by Lisa R. Fries, Nadia Khaled, Ivan Viveros Santos, Elvira Suniega-Tolentino, Motshewa Sesing, Melissa P. S. Toh, Chui Yuen Yang, Shiao Yng Chan, Shiao Yng Chan, Sara Colombo Mottaz

“…IntroductionNovel technologies have enabled the decentralization of many aspects of clinical trials, but little research has been done on the impact of these changes on the participant experience, trial operations, or the environment.MethodsA fully decentralized clinical trial conducted in Singapore is used as a case study to evaluate the operational outcomes, environmental impact (via life cycle assessment), and participants experience (qualitative interviews) of the decentralized model compared to a traditional study with in-person visits.ResultsThe decentralized study achieved high participant retention rates (97%) and high completion rates for clinical data, even for biological samples. …”
Get full text

A Seven-Year Retrospective Study on the Surveillance of Hepatitis B in Laos by Phimpha Paboriboune, Thomas Vial, François Chassagne, Philavanh Sitbounlang, Sengaloun Soundala, Stéphane Bertani, Davone Sengmanothong, Francois-Xavier Babin, Nicolas Steenkeste, Paul Dény, Pascal Pineau, Eric Deharo

“…A retrospective-descriptive cohort study was conducted on 3,857 HBV-infected patients. Information about infection status (viral load, VL), liver function (aminotransferases), and treatments was recorded. …”
Get full text

Management of Oro-Antral Communication: A Systemic Review of Diagnostic and Therapeutic Strategies by Gianna Dipalma, Angelo Michele Inchingolo, Irma Trilli, Laura Ferrante, Angela Di Noia, Elisabetta de Ruvo, Francesco Inchingolo, Antonio Mancini, Stefan Cocis, Andrea Palermo, Alessio Danilo Inchingolo

“…<b>Materials and Methods:</b> The systematic review was conducted following the PRISMA guidelines and registered on PROSPERO (CDR ID 623251). …”
Get full text

Styloid process phenotype and atheromatous plaque: Radiographic and bone density assessment in parathyroid disease by Adilia Mirela Pereira Lima Cid, Davi de Sá Cavalcante, Marcela Lima Gurgel, Ana Carolina Saraiva, Ana Alicia Sales Ricardo, Lúcio Mitsuo Kurita, Paulo Goberlânio de Barros Silva, Catarina Brasil d’Alva, Ana Rosa Pinto Quidute, Fabio Wildson Gurgel Costa

“…Material and methods: A cross-sectional case-control study was conducted with individuals diagnosed with PHPT (n = 25) and post-surgical hypoPT (n = 25). …”
Get full text

Tuberculous Otitis Media: A Mysterious Ailment by Saravana Selvan Velmurugan, Vivek Mariappan, Mohamed Siddique Samsudeen, Suresh Kumar Narayanan, Rhea Mathai, Tany James Maria

“…PTA revealed sensorineural hearing loss in 2 patients and conductive hearing loss in 1 patient. Treatment with regular ATT 4FDC (Anti Tubercular Treatment- Four Drug Combination) regimen was started as per weight band for 6 months. …”
Get full text

Assessment of the applied potential of sludge-derived hydrochar in terms of process parameters and product properties by Zhang, Chuang, Wang, Bingyu, Wang, Jixiang, Rong, Shaopeng,  Xie, Huifang, Qu, Hongxia, Feng, Yanfang

“…Evaluations of sludge characteristics in different regions and treatment processes were conducted, allowing HTC process parameters to be optimized in correlation with future resource utilization approaches. …”
Get full text

Autoantibodies to NR2A Peptide of the Glutamate/NMDA Receptor in Patients with Seizure Disorders in Neuropsychiatric Systemic Lupus Erythematosus by Yan Yang, Chao Yuan, Shu-qun Shen, Xue-er Wang, Qing-hua Mei, Wen-qing Jiang, Qin Huang

“…The present study was conducted to determine the serum levels of anti-NR2A antibodies in a large group of SLE patients, to investigate the possible correlation between the presence of the NR2A specific antibodies and NPSLE-related seizure disorders. …”
Get full text

Tribological degradation and corrosion of grinding disc wear contaminants in food by Segun Isaac Talabi, Ismaila Idowu Ahmed, Raheem Abolore Yahya, Taiwo Yahaya, Jeleel Adekunle Adebisi, Rasheedat Modupe Mahamood, Jamiu Kolawole Odusote, Mariam Kehinde Sulaiman, Lawrence Aderemi Olatunji, Sulaiman Abdulkareem

“…The aim of this study was to conduct qualitative and quantitative assessments of metallic contaminants in processed maize following wet and dry grinding operations, with discs from different manufacturing processes. …”
Get full text

Application of egg shell with fortified vermicompost in Capsicum cultivation: A strategy in waste management by Ishita Biswas, Debasis Mitra, Debanjan Mitra, Sourav Chattaraj, Ansuman Senapati, Abhinobo Chakraborty, Goutam Basak, Pradeep Das Mohapatra

“…Therefore, the present study has been carried out to assess the potentiality of the combination of ES with vermicompost (VC) and chicken feather protein hydrolysate (CFPH) on growth and yield improvement of Capsicum plants.Method A field study was conducted through randomized block design (RBD) with eight treatments having three replicates for each. …”
Get full text

An optimized method for AUV trajectory model in benthonic hydrothermal area based on improved slime mold algorithm by Chunmeng Jiang, Yiming Tang, Jianguo Wang, Wenchao Zhang, Min Zhou, Jiaying Niu, Lei Wan, Guofang Chen, Gongxing Wu, Xide Cheng

“…The simulation experiments were conducted in comparison with the artificial fish swarm algorithm (AFSA), the particle swarm optimization (PSO), and the compact cuckoo search (CCS). …”
Get full text

Evidence of vancomycin-resistant Staphylococcus aureus, multidrug-resistant S. aureus, and Enterococcus faecium-causing mastitis in Thailand and Cambodia by Sambo Na, Montira Intanon, Anyaphat Srithanasuwan, Wasana Chaisri, Witaya Suriyasathaporn

“…Disk diffusion tests were conducted for antibiotic susceptibility, and polymerase chain reaction was employed to detect AMR genes. …”
Get full text

Unravelling Lithium Interactions in Non-Flammable Gel Polymer Electrolytes: A Density Functional Theory and Molecular Dynamics Study by Nasser AL-Hamdani, Paula V. Saravia, Javier Luque Di Salvo, Sergio A. Paz, Giorgio De Luca

“…Furthermore, the second electrolyte demonstrated enhanced binding energies, implying greater ionic stability and conductivity relative to the first system. These findings offer insights into the Li⁺ transport mechanism at the molecular scale in the GPE by suggesting that lithium-ion transport does not occur by hopping between polymer functional groups but by diffusion into the solvent/counter anion system. …”
Get full text

The first multiple center prospective study of rhFSH CTP in patients undergoing assisted reproductive technology in China by Longmei Wu, Huayan Yin, Lingfang Guan, Guanjian Li, Junqiang Zhang, Qunshan Shen, Xiaoqing Ni, Chao Wang, Tianjuan Wang, Hao Geng, Chuan Xu, Yunxia Cao, Xiaojin He, Bing Song

“…A multi-center, open-label, randomized, positive-control, non-inferiority clinical trial was conducted. The study consisted of a phase III randomized design, with a 1:1 ratio favoring the rhFSH-CTP group over the control group. …”
Get full text

Case report: identification of novel variant in SLC26A2 gene and preimplantation genetic testing for monogenic disorders in preventing diastrophic dysplasia by Ziravard N. Tonyan, Yulia A. Nasykhova, Maria M. Danilova, Elena S. Shabanova, Olesya N. Bespalova, Igor Y. Kogan, Andrey S. Glotov

“…Case presentation This article presents a clinical case of preimplantation genetic testing for monogenic disorders (PGT-M) conducted for a family with two previous pregnancy losses due to diastrophic dysplasia in the fetus. …”
Get full text

Association between Visceral Fat and Bone Mineral Density in Both Male and Female Patients with Adult Growth Hormone Deficiency by Linman Li, Li Zhong, Xiaoya Zheng, Wenyi You, Yunting Wang, Jihui Yu, Xun Wu, Wei Ren, Gangyi Yang

“…In this study, we sought to investigate the relationship between various parameters of body composition and bone mineral density (BMD) as well as determine the role of visceral fat in determining the bone mass in patients with AGHD. Methods. We conducted a cross-sectional study on 57 patients with AGHD. …”
Get full text

Effects of the tide on the temporal and spatial physicochemical structure of the Kienké river estuary (South Atlantic Coast of Cameroon, Kribi) and its phytoplankton by Mama Anselme Crépin, Ghepdeu Gisele Flodore Youbouni, Fossi Tankoua Olivia, Bonga Manfred Desire, Abouga Bodo Willy Karol, Mandeng Thérésa Irma, Owona Edoa François Désiré, Tangko Noel Chuye, Ngoupayou Ndam Jules Rémi

“…The most sensitive parameters are as follows: a temperature ranging between 22.6°C and 31°C under the influence of atmospheric variations, electrical conductivity and salinity that are relatively high (0.22 < C. …”
Get full text

Low-Level Zoonotic Transmission of Clade C MERS-CoV in Africa: Insights from Scoping Review and Cohort Studies in Hospital and Community Settings by Andrew Karani, Cynthia Ombok, Silvia Situma, Robert Breiman, Marianne Mureithi, Walter Jaoko, M. Kariuki Njenga, Isaac Ngere

“…We also analyzed data from four cohort studies conducted in camel-keeping communities between 2018 and 2024 involving camel keepers, camel slaughterhouse workers, and hospital patients with acute respiratory illness (ARI). …”
Get full text

Dissecting the osmotic and oxidative stress responses in salt-tolerant and salt-sensitive wheat genotypes under saline conditions by Ulkar Ibrahimova, Javanshir Talai, Md. Mahadi Hasan, Irada Huseynova, Vaseem Raja, Anshu Rastogi, Hamideh Ghaffari, Marek Zivcak, Xinghong Yang, Marian Brestic

“…The current experiments were conducted on five wheat (Triticum aestivum L.) genotypes with contrasting salt tolerance capacities - Mirbashir 128, Gobustan, Gyzyl bughda, Fatima, and Zirva 80 under salinity stress caused by 150 mmol NaCl. …”
Get full text

Peripheral versus central cannulation of VA-ECMO for primary graft dysfunction after heart transplantation: A systematic review and meta-analysis by Eduard Ródenas-Alesina, MD, Aleix Olivella, MD, Ani Orchanian-Cheff, MiST, Farid Foroutan, PhD, Yasbanoo Moayedi, MD, MSc, Vivek Rao, MD, PhD, Filio Billia, MD, PhD, Heather J. Ross, MD, MHSc, Ana Carolina Alba, MD, PhD, Natasha Aleksova, MD, MSc

“…Background: Severe primary graft dysfunction (PGD) after heart transplantation (HT) is a major cause of death and requires veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Methods: We conducted a systematic review and meta-analysis including studies of adult HT recipients who required VA-ECMO for PGD to determine whether a peripheral or central configuration was associated with higher mortality. …”
Get full text

Mono-HOPE Versus Dual-HOPE in Liver Transplantation: A Propensity Score-Matched Evaluation of Early Graft Outcome by Dominik Thomas Koch, Dominik Thomas Koch, Micol Tamai, Malte Schirren, Malte Schirren, Moritz Drefs, Moritz Drefs, Severin Jacobi, Severin Jacobi, Christian M. Lange, Christian M. Lange, Matthias Ilmer, Matthias Ilmer, Matthias Ilmer, Hanno Nieß, Hanno Nieß, Bernhard Renz, Bernhard Renz, Jens Werner, Jens Werner, Markus Guba, Markus Guba, Dionysios Koliogiannis, Dionysios Koliogiannis

“…A retrospective analysis was conducted on 183 LiTx recipients, with 90 receiving mono-HOPE and 93 receiving dual-HOPE grafts. …”
Get full text