Comprehensive analysis of lncRNAs and mRNAs revealed potential participants in the process of avian reovirus infection by Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Shaqiu Zhang, Jinkang Li, Mingshu Wang, Mingshu Wang, Mingshu Wang, Mingshu Wang, Renyong Jia, Renyong Jia, Renyong Jia, Renyong Jia, Shun Chen, Shun Chen, Shun Chen, Shun Chen, Mafeng Liu, Mafeng Liu, Mafeng Liu, Mafeng Liu, Dekang Zhu, Dekang Zhu, Dekang Zhu, Dekang Zhu, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Xinxin Zhao, Ying Wu, Ying Wu, Ying Wu, Ying Wu, Qiao Yang, Qiao Yang, Qiao Yang, Qiao Yang, Juan Huang, Juan Huang, Juan Huang, Juan Huang, Xumin Ou, Xumin Ou, Xumin Ou, Xumin Ou, Di Sun, Di Sun, Di Sun, Di Sun, Bin Tian, Bin Tian, Bin Tian, Bin Tian, Yu He, Yu He, Yu He, Yu He, Zhen Wu, Zhen Wu, Zhen Wu, Zhen Wu, Anchun Cheng, Anchun Cheng, Anchun Cheng, Anchun Cheng

“…In our study, we collected duck embryo fibroblasts 18 h post-infection with ARV and conducted transcriptome sequencing analysis. The analysis revealed that 3,818 mRNA expressions were up-regulated, 4,573 mRNA expressions were down-regulated, 472 long noncoding RNAs (LncRNAs) were up-regulated, and 345 lncRNAs were down-regulated. …”
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Epigenetics and Inflammatory Markers: A Systematic Review of the Current Evidence by Valentina Gonzalez-Jaramillo, Eliana Portilla-Fernandez, Marija Glisic, Trudy Voortman, Mohsen Ghanbari, Wichor Bramer, Rajiv Chowdhury, Tamar Nijsten, Abbas Dehghan, Oscar H. Franco, Jana Nano

“…We included studies conducted on humans that examined the association between epigenetic marks (DNA methylation and/or histone modifications) and a comprehensive list of inflammatory markers. …”
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Prevalence of Diabetic Foot Ulcer and Associated Factors among Adult Diabetic Patients Who Attend the Diabetic Follow-Up Clinic at the University of Gondar Referral Hospital, North... by Tesfamichael G. Mariam, Abebaw Alemayehu, Eleni Tesfaye, Worku Mequannt, Kiber Temesgen, Fisseha Yetwale, Miteku Andualem Limenih

“…An institutional-based cross-sectional study was conducted in Gondar University Hospital, Ethiopia, to investigate foot ulcer occurrence in diabetic patients. …”
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Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity by Yazhou Bao, Qian Zhang, Hai Zhu, Yong Pei, Yaning Zhao, Yixin Li, Peiyun Ji, Dandan Du, Hao Peng, Guangyuan Xu, Xiaodan Wang, Zhiyuan Yin, Gan Ai, Xiangxiu Liang, Daolong Dou

“…Methods: To investigate the impact of MET on enhancing plant immune responses, we conducted assays measuring defense gene expression, reactive oxygen species (ROS) accumulation, mitogen-activated protein kinase (MAPK) phosphorylation, and pathogen infection. …”
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Spireoside Controls Blast Disease by Disrupting Membrane Integrity of Magnaporthe oryzae by Xu Liting, He Kaiwei, Guo Chunyu, Quan Cantao, Ma Yahuan, Zhang Wei, Ren Lifen, Wang Long, Song Li, Ouyang Qing, Yin Junjie, Zhu Xiaobo, Tang Yongyan, He Min, Chen Xuewei, Li Weitao

“…However, only a small fraction of antifungal metabolites have been identified from the tens of thousands of known plant secondary metabolites. In this study, we conducted a metabolomic analysis on both blast-resistant (Digu) and -susceptible (Lijiangxintuanheigu) rice varieties to uncover novel metabolites that enhance blast resistance. …”
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Atlantic mackerel population structure does not support genetically distinct spawning components [version 2; peer review: 1 approved, 2 approved with reservations] by Imanol Aguirre-Sarabia, Alice Manuzzi, Dorte Bekkevold, Natalia Díaz-Arce, Jessica Gomez-Garrido, Teunis Jansen, Marta Gut, Tyler S. Alioto, Sonia Sanchez-Maroño, Martin Castonguay, Naiara Rodriguez-Ezpeleta, Paula Álvarez

“…Given its highly migratory behaviour for feeding and spawning, several studies have been conducted to assess differentiation among spawning components to better define management units, as well as to investigate possible adaptations to comprehend and predict recent range expansion northwards. …”
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Exploring BCL2 regulation and upstream signaling transduction in venetoclax resistance in multiple myeloma: potential avenues for therapeutic intervention by Rodrigo Fonseca, Yuan Xiao Zhu, Laura A. Bruins, Joseph Ahmann, Cecilia de Bonolo Campos, Esteban Braggio, Xianfeng Chen, Mariano Arribas, Susie Darvish, Seth Welsh, Erin Meermeier, Kiran K. Mangalaparthi, Richard K. Kandasamy, Greg Ahmann, J. Erin Wiedmeier-Nutor, Akhilesh Pandey, Marta Chesi, P. Leif Bergsagel, Rafael Fonseca

“…Abstract Investigating venetoclax (VTX) resistance in multiple myeloma (MM) is crucial for the development of novel therapeutic strategies to tackle resistance. We conducted a multi-omic characterization of established VTX-resistant isogenic human myeloma cell lines (HMCL) and primary MM patient samples pre- and post-VTX treatment. …”
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Thoracic Surgery Consultations in COVID-19 Critically Ill Patients: Beyond Conservative Approach by Yasser Aljehani, Sharifah A. Othman, Yousif Almubarak, Ayman Elbaz, Mohammed Sabry, Farouk Alreshaid, Hatem Y. Elbawab, Zeead M. Alghamdi, Mohammed Alshahrani

“…A retrospective study was conducted in an academic healthcare institute in the Eastern Province of Saudi Arabia. …”
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Flexible Bench-Scale Recirculating Flow CPC Photoreactor for Solar Photocatalytic Degradation of Methylene Blue Using Removable TiO2 Immobilized on PET Sheets by Doaa M. EL-Mekkawi, Norhan Nady, Nourelhoda A. Abdelwahab, Walied A. A. Mohamed, M. S. A. Abdel-Mottaleb

“…Immobilization of TiO2 on PET was conducted by dip coating process followed by exposing to mild heat and pressure. …”
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Waste heat recovery cycles integration into a net-Zero emission solar-thermal multi-generation system; Techno-economic analysis and ANN-MOPSO optimization by Pradeep Kumar Singh, Ali Basem, Rebwar Nasir Dara, Mohamed Shaban, Sarminah Samad, Raymond Ghandour, Ahmad Almadhor, Samah G. Babiker, Iskandar Shernazarov, Ibrahim A. Alsayer

“…Upon validating the primary components, the system is thoroughly evaluated in terms of energy, exergy, and economic performance, and a parametric study is conducted to assess the influence of key operational parameters. …”
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Tadalafil treatment for fetuses with early-onset growth restriction: a protocol for a multicentre, randomised, placebo-controlled, double-blind phase II trial (TADAFER IIb) by Hiroaki Tanaka, Yasuhiro Tanaka, Yoichi Aoki, Masayuki Endo, Tomoaki Ikeda, Shintaro Maki, Masafumi Nii, Kayo Tanaka, Satoshi Tamaru, Toru Ogura, Yuki Nishimura, Tomomi Kotani, Akihiko Sekizawa, Masahiko Nakata, Koji Nakamura, Kenji Nagao, Ichiro Yasuhi, Hiroshi Kawamura, Sho Takakura, Mayumi Kotera, Takafumi Ushida, Norihiko Kikuchi, Tadatsugu Kinjo, Mayumi Takano, Sachie Suga, Michi Kasai, Osamu Yasui, Yuka Maegawa, Shigeru Aoki, Yoshio Yoshida

“…To establish further evidence for the efficacy of tadalafil in this setting, we planned a multicentre, randomised, placebo-controlled, double-blind trial.Methods and analysis This trial will be conducted in 180 fetuses with fetal growth restriction enrolled from medical centres in Japan; their mothers will be randomised into three groups: arm A, receiving two times per day placebo; arm B, receiving one time per day 20 mg tadalafil and one time per day placebo and arm C, receiving 20 mg two times per day tadalafil. …”
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A phase-transited lysozyme coating doped with strontium on titanium surface for bone repairing via enhanced osteogenesis and immunomodulatory by Yu Zhang, Yu Chen, Yidan Shi, Hongkun Hu, Zhongyu Dai, Zhichen Liu, Xuanan Li

“…A series of cell and animal experiments were conducted to investigate the biological functions of PTL-Sr coatings.ResultsThe characterization indicates the successful preparation of PTL-Sr coatings. …”
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Adsorptive removal of toxic heavy metal and dyes from wastewater by rice husk (lignocellulosic biomass) derived activated biochar: A fixed-bed column adsorption study by Md. Mahmudur Rahman, Mohd. Maniruzzaman, Nor ealam, Parvej Mahmud, Sumiya Khatun, Md. Kaowsar Hossain, Md. Ismail Hossain, Md. Hasanuzzaman, Md. Ashraful Alam, Md. Al-amin, Bijoy Chandra Ghos

“…The experiments were conducted to optimize the effect of influential factors like concentration, flowrates, and bed height. …”
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Emotion dysregulation in youths with obsessive-compulsive disorder and its implication for treatment - An exploratory study from the TECTO trial: A protocol and statistical analysi... by Christine Lykke Thoustrup, Camilla Uhre, Valdemar Uhre, Melanie Ritter, Signe Vangkilde, Janus Engstrøm, Jane Lindschou, Christian Gluud, Anne Katrine Pagsberg, Markus Harboe Olsen

“…Analyses 1–4 will be conducted for all OCD participants and separately for the two treatment groups. …”
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Effect of non-contact induction heating on HA coatings and bone cement, an ex vivo study [version 2; peer review: 2 approved, 1 approved with reservations] by Robert Kamphof, Dr. Bart G.C.W. Pijls, Dr. Rob G.H.H. Nelissen, Jeroen Mesman-Vergeer, Dr. Giuseppe Cama

“…Methods Characterisation of hydroxyapatite coatings and adhesion strength tests were conducted according to standards set by the International Organisation for Standardisation (ISO 13779-2). …”
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A novel virtual inductor optimization methodology of virtual synchronous generators for enhanced power decoupling by Xin Zhang, Lijiao Gong, Yanjun Zhang, Xiaolei Ma, Lianshan Han, Santao Jiang, Weiji Zhou

“…Finally, a series of comparative experiments is conducted to demonstrate its superior dynamic, static performance and enhanced power decoupling characteristics. …”
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Morphological and Interfacial Engineering with a Surfactant Additive Toward High‐Performance Blade‐Coated Quantum Dot Light‐Emitting Diodes by Wei‐Zhi Liu, Hong‐Wei Duan, Shu‐Guang Meng, Dong‐Ying Zhou, Liang‐Sheng Liao

“…These modifications not only enhanced the conductivity of the PEDOT:PSS film due to the conformation changes, but also improved energy level alignment, leading to improved hole‐injecting properties and reduced driving voltages in QLED devices. …”
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Operation Effect Analysis of Dynamic Stabilizer Considering the Characteristics of Fasteners by CHEN Taimao, WANG Lihua, HUANG Hongyi, WANG Jiongli, ZHAO Zemin, JIANG Wei

“…［Objective］ Research is conducted on the influence and significance of the excitation frequency of the dynamic stabilization device and the mechanical characteristics of rail fasteners on the operation effect of the dynamic track stabilizer in order to provide some reference for the operation of the dynamic stabilizer. …”
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Associations of gut microbiota with disease development, disease activity, and therapeutic effects in patients with systemic lupus erythematosus by Junko Nishio, Hiroshi Sato, Eri Watanabe, Hiroaki Masuoka, Kotaro Aoki, Mai Kawazoe, Risa Wakiya, Soichi Yamada, Sei Muraoka, Shotaro Masuoka, Tomoki Hayashi, Satoshi Mizutani, Zento Yamada, Keiko Koshiba, Izumi Irita, Miwa Kanaji, Karin Furukawa, Nobuyuki Yajima, Hiroaki Dobashi, Wataru Hirose, Yoshikazu Ishii, Wataru Suda, Toshihiro Nanki

“…We compared new-onset SLE (NOSLE, n = 25), SLE in remission (RemSLE, n = 30), and healthy controls (HC, n = 30) cross-sectionally and conducted the first longitudinal analysis of NOSLE patients (n = 22) from pre-intervention to remission over 12 months. …”
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Dietary (poly)phenol intake is associated with cardiometabolic health parameters in adolescents by Emily P. Laveriano-Santos, Sara Castro-Barquero, Camila Arancibia-Riveros, Ruiz-León Ana María, Rosa Casas, Ramón Estruch, Patricia Bodega, Mercedes de Miguel, Amaya de Cos-Gandoy, Jesús Martínez-Gómez, Gloria Santos-Beneit, Juan M. Fernández-Alvira, Rodrigo Fernández-Jiménez, Rosa M. Lamuela-Raventós, Anna Tresserra-Rimbau

“…A cross-sectional study was conducted in 944 individuals aged 11–14 years enrolled in the SI! …”
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