AI-based tumor-infiltrating lymphocyte scoring system for assessing HCC prognosis in patients undergoing liver resection by Zhiyang Chen, Tingting Xie, Shuting Chen, Zhenhui Li, Su Yao, Xuanjun Lu, Wenfeng He, Chao Tang, Dacheng Yang, Shaohua Li, Feng Shi, Huan Lin, Zipei Li, Anant Madabhushi, Xiangtian Zhao, Zaiyi Liu, Cheng Lu

“…Given the heterogeneous outcomes in patients with HCC undergoing liver resection, this study aims to develop an AI-based system to quantify CD8+ TILs and assess their prognostic value for patients with HCC. Methods: We conducted a retrospective multicenter study on patients undergoing liver resection across three cohorts (N = 514). …”
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Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins by Maria Angelica Freitas-Cortez, Fatemeh Masrorpour, Hong Jiang, Iqbal Mahmud, Yue Lu, Ailing Huang, Lisa K. Duong, Qi Wang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Bo Wei, Wai-Kin Chan, Kevin Lin, Jie Zhang, Efrosini Tsouko, Shonik Ganjoo, Hampartsoum B. Barsoumian, Thomas S. Riad, Yun Hu, Carola Leuschner, Nahum Puebla-Osorio, Jing Wang, Jian Hu, Michael A. Davies, Vinay K. Puduvalli, Cyrielle Billon, Thomas P. Burris, Philip L. Lorenzi, Boyi Gan, James W. Welsh

“…We worked with cell lines including PD1-sensitive, PD1-resistant, B16F10, and QPP7 glioblastoma cells, and conducted in vivo studies in syngeneic 129 Sv/Ev, C57BL/6, and conditional knockout mice with Rora deletion specifically in CD8+ T cells, Cd8 cre;Rora fl mice. …”
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Development and validation of an explainable machine learning model for mortality prediction among patients with infected pancreatic necrosisResearch in context by Caihong Ning, Hui Ouyang, Jie Xiao, Di Wu, Zefang Sun, Baiqi Liu, Dingcheng Shen, Xiaoyue Hong, Chiayan Lin, Jiarong Li, Lu Chen, Shuai Zhu, Xinying Li, Fada Xia, Gengwen Huang

“…A benchmarking test, involving nested resampling, automatic hyperparameter tuning and random search techniques, was conducted to select the ML model. Sequential forward selection method was employed to select the optimal feature subset from 31 candidate subsets to simplify the model and maximize predictive performance. …”
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A China dataset of soil properties for land surface modelling (version 2, CSDLv2) by G. Shi, W. Sun, W. Shangguan, Z. Wei, H. Yuan, L. Li, X. Sun, Y. Zhang, H. Liang, D. Li, F. Huang, Q. Li, Q. Li, Y. Dai

“…As the soil profiles used in this study mainly originate from the Second National Soil Survey of China, conducted during the 1970s and 1980s, they could provide new perspectives on soil changes, together with existing maps based on soil profiles from the 2010s. …”
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Safety of a co-designed cognitive behavioural therapy intervention for people with type 1 diabetes and eating disorders (STEADY): a feasibility randomised controlled trialResearch... by Marietta Stadler, Natalie Zaremba, Amy Harrison, Jennie Brown, Divina Pillay, Jacqueline Allan, Rachael Tan, Salma Ayis, Emmanouela Konstantara, Janet Treasure, David Hopkins, Khalida Ismail

“…Baseline mental health data (Structured Clinical Interview for DSM-5, SCID-5RV), and secondary biomedical outcomes (HbA1c; glucose time in range; TIR) and person-reported outcome measures (PROM: Diabetes Eating Problems Survey-Revised, DEPS-R; Eating Disorder Examination Questionnaire Short, EDE-QS; Type 1 Diabetes Distress Scale, T1DDS; Generalised Anxiety Disorder Assessment, GAD-7; Patient Health Questionnaire, PHQ-9; Impact of Diabetes Profile, DIDP) were collected. Analyses were conducted as intention-to-treat. ClinicalTrials.gov NCT05140564. …”
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Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade by Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

“…Methods Flow cytometric, Western blotting, proteomics analysis, analysis of public database data, genetically modified cell line models, T cell coculture, crystal violetstaining, ELISA, metabonomic and clinical tumour samples were conducted to assess the role of EDEM3 in immune escape and itsmolecular mechanisms. …”
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Artificial intelligence contouring in radiotherapy for organs-at-risk and lymph node areas by Céline Meyer, Sandrine Huger, Marie Bruand, Thomas Leroy, Jérémy Palisson, Paul Rétif, Thomas Sarrade, Anais Barateau, Sophie Renard, Maria Jolnerovski, Nicolas Demogeot, Johann Marcel, Nicolas Martz, Anaïs Stefani, Selima Sellami, Juliette Jacques, Emma Agnoux, William Gehin, Ida Trampetti, Agathe Margulies, Constance Golfier, Yassir Khattabi, Olivier Cravéreau, Alizée Renan, Jean-François Py, Jean-Christophe Faivre

“…It was a single-center study conducted in radiation department at the Lorraine Cancer Institute. …”
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Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) by Junyu Yan, Kai Luo, Bo Wang, Jiaxin He, Can Li, Jiang Zhou, Wenhao Lai, Xin Zhou, Jingwei Ye, Mingzhu Pan, Yingbing Su, Weihua Gao, Kai Guo, Chengmin Zhao

“…The current study was conducted to investigate the influences of dietary compound acidifier (CA, Formic acid (45 %), malic acid (0.3 %), Fumaric acid (0.6 %) and Succinic acid (0.6 %), Biomin Feed Additives (Shanghai) Ltd) on the growth, anti-oxidation, immunity, and intestinal health of channel catfish (Ictalurus punctatus). …”
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Influence of Exposure to Different Green Rooftop Spaces on Stress Restoration of College Students by Zhixiong ZHUO, Liang DONG

“…Field measurements are conducted during the daytime on a sunny and windless day, with no significant difference between the physical environments of different green rooftop spaces. 35 college student volunteers participate in the experiment, all of whom are daily users of green rooftop space. …”
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Study on the status of liver function abnormalities and its related factors in patients with severe mental disorders in Shanghai community by ZHANG Yixuan, CHEN Chunmei, ZHU Youwei, ZHU Yi, HE Siyuan, LIU Yanli, WANG Na, CAI Jun, XIE Bin, ZHANG Weibo

“…Questionnaire survey, physical examination and laboratory tests were conducted to obtain their demographic characteristics and liver function indicators such as alanine aminotransferase (ALT) and total bilirubin (TBil). …”
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La datation des aqueducs lyonnais : un état des lieux by Aldo Borlenghi, Catherine Coquidé

“…As a result, a global analysis was needed.For the Mont d’Or aqueduct, a single excavation conducted around 30 years ago near the entry into Lyon (52-54 rue de la Favorite) brought to light a sherd of Drag 15/17 type terra sigillata pottery in the canal foundation trench. …”
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Gambaran Profil Lipid pada Pasien Sindrom Koroner Akut di Rumah Sakit Khusus Jantung Sumatera Barat Tahun 2011-2012 by Fitri Zahara, Masrul Syafri, Eti Yerizel

“…Descriptive research has been conducted with a a cross-sectional study and a retrospective approach using medical record about the result of lipid profile test (total cholesterol, HDL, LDL, and triglycerides) at the heart hospital of West Sumatera to describe the lipid profile in patients with ACS in 2011-2012. …”
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A Predictive Model for Pulmonary Aspergillosis in ICU Patients: A Multicenter Retrospective Cohort Study by Li Y, Ren X, Wang Q, Shen S, Li Y, Qian X, Tang Y, Jia J, Zhang H, Ding J, Song Y, Zhang S, Wang S, Xu Y, Jiang Y, He X, Dai M, Zhong L, Xiong Y, Pan Y, Wang M, Shao H, Cai H, Huang L, Wang H

“…This study aimed to develop a risk prediction model for IPA by integrating clinical and microbiological characteristics.Methods: This retrospective study was conducted in adult intensive care units (ICUs) of 17 medical centers in China. …”
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Stability Analysis of Dry Yield of Z. multiflora Boiss. under Drought Stress and Mycorrhizal Fungi Symbiosis by Ashraf Aghababapoor Dehkordi, Sadollah Houshmand, Shahram Mohammady

“…Methods: This study was conducted on eight Z. multiflora ecotypes collected from Safashahr, Neyriz, Khanekhore, and Fasa from Fars Province, ‎ Fooladshahr, Baharestan, and Kolahghazi from Isfahan Province, and Qasreghand from Sistan and Baluchestan Province. …”
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Normative Database of Spatiotemporal Gait Metrics Across Age Groups: An Observational Case–Control Study by Lianne Mobbs, Vinuja Fernando, R. Dineth Fonseka, Pragadesh Natarajan, Monish Maharaj, Ralph J. Mobbs

“…By doing so, we aim to enhance the clinical utility of gait analysis in diagnosing and managing health conditions. Methods: We conducted an observational case–control study involving 313 healthy participants. …”
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HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in... by Augustine T Choko, Elizabeth L Corbett, Nigel Stallard, Hendramoorthy Maheswaran, Aurelia Lepine, Cheryl C Johnson, Doreen Sakala, Thokozani Kalua, Moses Kumwenda, Richard Hayes, Katherine Fielding

“…<h4>Methods and findings</h4>An adaptive multi-arm, 2-stage cluster randomised trial was conducted between 8 August 2016 and 30 June 2017, with antenatal care clinic (ANC) days (i.e., clusters of women attending on a single day) as the unit of randomisation. …”
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Perbedaan Rerata Kadar Soluble Fms-Like Tyrosine Kinase-1 (Sflt-1) Serum pada Penderita Early Onset, Late Onset Preeklampsia Berat / Eklampsia dan Kehamilan Normal by Laila Rahmi, Rahmatina B. Herman, Yusrawati .

“…</em><em> </em><em>This study was conducted in Dr. M. Djamil hospital, dr. Reksodiwiryo </em><em>TK. …”
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Performance evaluation of four cascade impactors for airborne ultrafine-particle (UFP) collection: the influence of particle type, concentration, mass, and chemical nature by E. Eckenberger, A. Mittereder, N. Gawlitta, N. Gawlitta, J. Schnelle-Kreis, J. Schnelle-Kreis, M. Sklorz, D. Brüggemann, R. Zimmermann, R. Zimmermann, A. C. Nölscher

“…However, their small mass presents challenges for sampling and chemical characterization methods. Therefore, we conducted a comprehensive characterization and comparison of four cascade impactors suitable for separating and collecting UFPs – namely, the 120R Micro-Orifice Uniform Deposit Impactor (120R MOUDI-II), ultraMOUDI, electrical low-pressure impactor (ELPI), and personal nanoparticle sampler (PENS) – under controlled laboratory conditions and in a field application.…”
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The role of teachers and administrators in supporting the adaptation of students with special needs in mainstream high schools by Amir Mahmood, Xiao Huang, Nadia Rehman

“…In addition, the study was conducted within a specific context and population, which may limit the generalizability of the findings to other settings. …”
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homeRNA self-blood collection enables high-frequency temporal profiling of presymptomatic host immune kinetics to respiratory viral infection: a prospective cohort studyResearch in... by Fang Yun Lim, Hannah G. Lea, Ashley M. Dostie, Soo-Young Kim, Tammi L. van Neel, Grant W. Hassan, Meg G. Takezawa, Lea M. Starita, Karen N. Adams, Michael Boeckh, Joshua T. Schiffer, Ollivier Hyrien, Alpana Waghmare, Erwin Berthier, Ashleigh B. Theberge

“…The remote (decentralized) study framework enables conduct of large-scale population-wide longitudinal mechanistic studies. …”
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