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Potential Azo-8-hydroxyquinoline derivatives as multi-target lead candidates for Alzheimer's disease: An in-depth in silico study of monoamine oxidase and cholinesterase inhibitors...
Published 2025-01-01“…Cognitive dysfunction in Alzheimer's disease results from a complex interplay of various pathological processes, including the dysregulation of key enzymes such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and monoamine oxidase B (MAO-B). …”
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302
Fuzzy Adaptive Prescribed Performance Fault-Tolerant Control for HFVs with Fixed-Time Convergence Guarantee
Published 2022-01-01“…Fuzzy logic systems (FLSs) are employed to handle unknown dynamics, and minimal learning parameter (MLP) technique is incorporated into the design for the purpose of alleviating computation burden. Closed-loop stability is rigorously proved via Lyapunov stability theory, and simulation results are eventually given to validate the effectiveness of the proposed control strategy.…”
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303
Properties of the wormhole model in de Rham–Gabadadze–Tolley like massive gravity with specific matter density
Published 2025-01-01“…The complexity factor of the proposed model is also discussed.…”
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304
Model for Vaccine Design by Prediction of B-Epitopes of IEDB Given Perturbations in Peptide Sequence, In Vivo Process, Experimental Techniques, and Source or Host Organisms
Published 2014-01-01“…In a recent work, we introduced a new quantitative structure-property relationship theory for the study of perturbations in complex biomolecular systems. …”
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305
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Fast Atomic Charge Calculation for Implementation into a Polarizable Force Field and Application to an Ion Channel Protein
Published 2015-01-01“…Here, we present a very fast computational quantum mechanical method, the Bond Polarization Theory (BPT). …”
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307
Numerical Studies of the Gas-Solid Hydrodynamics at High Temperature in the Riser of a Bench-Scale Circulating Fluidized Bed
Published 2012-01-01“…The hydrodynamics of circulating fluidized beds (CFBs) is a complex phenomenon that can drastically vary depending on operational setup and geometrical configuration. …”
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308
A Diversified Spectrometric and Molecular Docking Technique to Biophysical Study of Interaction between Bovine Serum Albumin and Sodium Salt of Risedronic Acid, a Bisphosphonate fo...
Published 2018-01-01“…The formation of a BSA-RSN complex was confirmed from UV-Vis spectroscopy. The static type of quenching shown for RSN to BSA was verified from Stern–Volmer and modified Stern–Volmer equations. …”
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309
Effect of Axial Vibration on Sliding Frictional Force between Shale and 45 Steel
Published 2018-01-01“…Meanwhile, a friction coupling model was established based on the Hertz contact theory and Dahl model. The corresponding computational program was developed in Matlab/Simulink environment. …”
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310
Binary plant rhizome growth-based optimization algorithm: an efficient high-dimensional feature selection approach
Published 2025-01-01“…This paper introduces an innovative intelligent optimization algorithm, the Plant Root Growth Optimization (PRGO) algorithm, inspired by the structure of plant rhizomes and the way they absorb nutrients.In the algorithm, the plant rhizomes are divided into two categories, the taproot and the fibrous root.the growth process of the taproot plants is associated with the global exploration search, and the growth process of the fibrous root plants relates to the local exploitation search.The global asymptotic convergence of the algorithm is proved by applying Markov’s correlation theory, and simulation results using CEC2014 and CEC2017 test sets show that the proposed algorithm has excellent performance.Moreover, a binary variant of this algorithm (BPRGO) has been specifically crafted in this research to tackle the complexities of high-dimensional feature selection issues. …”
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311
A Guide to Light-Cone PDFs from Lattice QCD: An Overview of Approaches, Techniques, and Results
Published 2019-01-01“…For more than half a century, there has been a joint experimental and theoretical effort to obtain these partonic functions. However, the complexity of the strong interactions has placed severe limitations, and first-principle information on these distributions was extracted mostly from their moments computed in Lattice QCD. …”
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312
Quantum Speedup of the Dispersion and Codebook Design Problems
Published 2024-01-01Get full text
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313
Advancements in Physics-Informed Neural Networks for Laminated Composites: A Comprehensive Review
Published 2024-12-01“…Physics-Informed Neural Networks (PINNs) integrate physics principles with machine learning, offering innovative solutions for complex modeling challenges. Laminated composites, characterized by their anisotropic behavior, multi-layered structures, and intricate interlayer interactions, pose significant challenges for traditional computational methods. …”
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314
Variation-Difference Method of Calculation of Layered Rubber-Metal Vibration Isolators Used for Protection of Reinforced Concrete Buildings from Anthropogenic Vibration
Published 2024-02-01“…Variation-difference method (VDM) is the closest to the finite element method (FEM) in terms of its computational capabilities. It is possible to create program modules that repeatedly and automatically solve three-dimensional problems of elasticity theory taking into account the changed geometry of the vibration isolator: the dimensions of the product, the location of perforations within the rubber layers, as well as the thickness of the rubber layer and other parameters important for obtaining an effective technical solution for vibration isolation of buildings. …”
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315
Study of thermal performance of a solar collector-based hydraulic system
Published 2023-06-01“…It is possible to obtain missing experimental data using interpolation, extrapolation and similarity theory.…”
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316
STUDY OF COMPATIBILITY OF METHODS AND TECHNOLOGIES OF HIGH-LEVEL PROTOCOLS AND ERROR-CORRECTING CODES
Published 2024-12-01“…Polar codes have since been integrated into 5G systems due to their efficiency and low complexity, marking a milestone in modern coding theory. …”
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317
Decompositions of Circulant-Balanced Complete Multipartite Graphs Based on a Novel Labelling Approach
Published 2022-01-01“…Graph theory is extremely important in complex systems, particularly in computer science. …”
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318
Targeting necroptosis in MCF-7 breast cancer cells: In Silico insights into 8,12-dimethoxysanguinarine from Eomecon Chionantha through molecular docking, dynamics, DFT, and MEP stu...
Published 2025-01-01“…This study presents the first computational exploration of SG-A interactions with key necroptotic proteins-RIPK1, RIPK3, and MLKL-through molecular docking, molecular dynamics (MD), density functional theory (DFT), and molecular electrostatic potential (MEP) analyses. …”
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319
Neural activity responsiveness by maturation of inhibition underlying critical period plasticity
Published 2025-01-01Get full text
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320
The decoupling of moduli about the standard embedding
Published 2025-01-01“…Abstract We study the cohomology of an elliptic differential complex arising from the infinitesimal moduli of heterotic string theory in the supergravity approximation. …”
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