Frequency and factors associated with loss to follow-up in newly diagnosed rheumatoid arthritis patient: a single-centre study by Sumariyono Sumariyono, Rudy Hidayat, Faisal Parlindungan, Suryo Anggoro Kusumo Wibowo, Anna Ariane, Johanda Damanik, Abirianty Priandani Araminta, Ryzkianty Annis Nurdin

“…The reasons for LTFU were distance from house to hospital constraints (76%), busy (56%), transportation constraints (38%), dissatisfaction with the outpatient clinic service (21%), lack of information about their disease (18%), having other comorbidities that compelled them to go to another department’s clinic (15%), difficulties understanding the clinic registration flow system (9%), and having minimal symptoms (6%). …”
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Randomised controlled trial comparing intraoperative cell salvage and autotransfusion with standard care in the treatment of hip fractures: a protocol for the WHITE 9 study by Mike Murphy, Nicholas Parsons, James Mason, Juul Achten, Duncan Appelbe, Edward Dickenson, Damian Griffin, Katy Mironov, Matthew Wyse, Amrita Athwal, Xavier Luke Griffin, Heather O'Connor

“…Hip fracture and the urgent surgery is associated with acute blood loss, compounding patients’ pre-existing comorbidities including anaemia. Approximately 30% of patients require a donor blood transfusion in the perioperative period. …”
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Doctor, what is my risk of bleeding after cardiac surgery while on combined anticoagulant with antiplatelet therapy? A validated nomogram for risk assessment by Haolong Han, Haolong Han, Hang Xu, Hang Xu, Jifan Zhang, Weihui Zhang, Yi Yang, Xia Wang, Li Wang, Dongjin Wang, Weihong Ge

“…BackgroundPatients with comorbid coronary artery disease and valvular heart disease usually undergo coronary artery bypass grafting alongside valve replacement or ring repair surgeries. …”
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Comparing the effectiveness, safety and tolerability of interventions for depressive symptoms in people with multiple sclerosis: a systematic review and network meta-analysis proto... by Amalia Karahalios, Allan G Kermode, Yvonne C Learmonth, Julia Lyons, Stephanie Campese, Alexandra Metse, Claudia H Marck

“…Background Comorbid depression is prevalent in people with multiple sclerosis (MS). …”
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The modern options of chronic hepatitis C antiviral therapy with daclatasvir: results of named patient program by V. T. Ivashkin, M. V. Mayevskaya, D. T. Abdurakhmanov, I. G. Bakulin, N. I. Geyvandova, M. L. Zubkin, S. N. Kizhlo, A. V. Kuznetsova, I. B. Latysheva, N. A. Mamonova, V. G. Morozov, O. I. Sagalova, Ye. V. Esaulenko, Ye. O. Lyusina

“…The options of antiviral therapy (AVT) in the stages of severe liver fibrosis and cirrhosis (LC) as well as in the patients with comorbidities for the long time were limited to the standard therapy by pegilated interferon (peg-IFN) in combination to ribavirin (RBV). …”
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Risk of SARS-CoV-2 infection among front-line healthcare workers in Northeast Brazil: a respondent-driven sampling approach by Thalia Velho Barreto de Araújo, Demócrito de Barros Miranda-Filho, Ricardo Arraes de Alencar Ximenes, Ulisses Ramos Montarroyos, Celina Maria Turchi Martelli, Maria de Fátima Pessoa Militão de Albuquerque, Wayner Vieira de Souza, Cresio Romeu Pereira, Cynthia Braga, Celia Landmann Szwarcwald, Paulo Roberto Borges de Souza-Junior, Morgana Nascimento Xavier, Clarice Neuenschwander Lins de Morais, Gabriela Diniz Militao de Albuquerque, Cristiane Bresani-Salvi, Carolline Araújo Mariz, Noemia Teixeira de Siqueira-Filha, Jadson Mendonça Galindo, Cláudio Luiz França-Neto, Jessyka Mary Vasconcelos Barbosa, Maria Amelia Sousa Mascena Veras, Luana Nepomuceno Gondim Costa Lima, Luciane Nascimento Cruz, Carl Kendall, Ligia Regina Franco Sansigolo Kerr

“…Nurses were older with more comorbidities (hypertension and overweight/obesity) than the other staff. …”
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A system‐based intervention to reduce Black‐White disparities in the treatment of early stage lung cancer: A pragmatic trial at five cancer centers by Samuel Cykert, Eugenia Eng, Paul Walker, Matthew A. Manning, Linda B. Robertson, Rohan Arya, Nora S. Jones, Dwight E. Heron

“…For the retrospective baseline, crude treatment rates were 78% for White patients vs 69% for Black patients (P < 0.001); difference by race was confirmed by a model adjusted for age, treatment site, cancer stage, gender, comorbid illness, and income‐odds ratio (OR) 0.66 for Black patients (95% CI 0.51‐0.85, P = 0.001). …”
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A descriptive study of blood pressure in people with self-reported substance use seeking health care in region F, Johannesburg, South Africa by K.E. Oladimeji, S. Gumede, A. Nyatela, S. Nonyukela, R. Mohale, S.T. Lalla-Edward, D. Dwarka

“…Independent factors associated with elevated blood pressure were increasing age - 30-39 years old (adjusted odds ratio (aOR) 2.78 [95 %CI 1.42–5.41], 40–49 years old (aOR 3.81 [95 %CI 1.95–7.46]), 50+ years (aOR 5.00 [95 %CI 2.45–10.20] and having comorbidities (aOR 2.35 [95 %CI 1.31–4.22]). Conclusions: Prevalence of elevated blood pressure was high and only a few of these were on anti-hypertensive treatment. …”
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Assessing the Comparative Efficacy and Safety of Warfarin and Rivaroxaban for Cancer Associated Thrombosis: Experience From a Resource Limited Setting by Abel Tenaw Tasamma, Tsegab Alemayehu Bukate, Abdulrahim Mehadi, Bereket Tagesse Handiso, Beniam Yohannes Kassa, Eman Omer Hassen, Zekarias Seifu Ayalew, Dawit Habtie Tegegne, Gebeyehu Tessema Azibte, Tigest Abebaw Zewdie, Tinsaye Zergaw Shihur, Yonas Degelo Geremamo, Yeabsira Dessalegne Mesfin, Rediet M. Alemayehu, Amanuel Kassu Asefa, Fozia Abdela, Addisu Melkie

“…The baseline mean (standard deviation) age of the patients was 48.4 (15.0) and 140 (69.7%) of them were female. 41.3% of the participants had one or more comorbidities, and the most common types of cancer were gynecologic (28.9%), hematologic (21.4%), and intra‐abdominal (16.9%). …”
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The blood pressure lowering effect of beetroot juice is impaired in periodontitis and recovered after periodontal treatment by Nydia Y. Sanchez-Orozco, Bob T. Rosier, Alondra Ruiz-Gutierrez, Fabiola Marquez-Sandoval, Alejandro Artacho, Lucrecia Carrera-Quintanar, Alex Mira

“…Future work should also aim to determine if nitrate prebiotic supplementation and/or tongue cleaning could improve the treatment of periodontitis and its associated comorbidities.…”
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Impact of Mandatory Preoperative Dental Screening on Infective Endocarditis in Patients Undergoing Surgical Valve Replacement by Lytfi Krasniqi, MD, Poul Erik Mortensen, MD, Emil Johannes Ravn, MD, Marlene Tofterup, MD, Henrik Nissen, MD, PhD, Christian Juhl Terkelsen, MD, PhD, DMSCi, Niels Holmark Andersen, MD, PhD, DMSCi, Ivy Modrau, MD, DMSCi, Kasper Stokbro, DDS, PhD, Jonas A. Povlsen, MD, PhD, Oke Gerke, MSc, PhD, DMSCi, Jesper Hallas, MD, DMSCi, Marie-Annick Clavel, DVM, PhD, Lars Peter Schødt Riber, MD, PhD, DMSCi, Jordi Sanchez Dahl, MD, PhD, DMSCi

“…Patients in the MPDS were older with higher rates of coexisting comorbidities. During a median follow-up of 2.6 years, 3.3% (n = 40) developed IE. …”
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Comparative Analysis of 95 Patients with Different Severity in the Early Outbreak of COVID-19 in Wuhan, China by Fang He, Xue-feng Ding, Meng Cao, Hai-ying Gong, Xiang-zhen Fu, Jie Luo, Kui Liu, Zhou-zhou Tian, Lin Luo, Yu-yuan Fan, Ting Li, Qian-Jing Yao, Xiao-ju Chen, Xiang-lin Duan, Li Chen, Li Jiang

“…Severe and critical cases were older, more likely to have shortness of breath, more likely to have underlying comorbidities, and more likely to have abnormal laboratory findings than common cases. …”
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Seasonal trends of pyogenic spondylodiscitis in Japan: a nationwide inpatient database study by Takayuki Motoyoshi, Takahisa Ogawa, Kazuyuki Fukushima, Satoshi Kutsuna, Haggai Schermann, Kiyohide Fushimi, Toshitaka Yoshii

“…Sepsis was the most common concomitant infection, occurring in 10.4 % of patients.The risk factors for in-hospital mortality were being elderly, male, having a low BMI, and high comorbidities. Among patients aged over 65, aspiration pneumonia and sepsis were risk factors for death throughout the year. …”
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Excessive daytime sleepiness and its predictors among type 2 diabetes mellitus patients at central ethiopia by Alemayehu Wondie, Mitiku Mammo Taderegew, Betemariam Girma, Atsede Getawey, Zufan Tessema, Ambaw Abebaw Emrie, Tamene Fetene Terefe

“…Age (AOR: 1.08; 95%CI: 1.03, 1.12), frequent snoring (AOR: 2.9; 95%CI: 1.24, 6.80), comorbid hypertension (AOR: 2.64; 95%CI: 1.17, 5.96), obesity (AOR: 2.7; 95%CI: 1.03, 7.13), and poor glycemic control (AOR: 6.68; 95%CI: 1.83, 24.41) were independently associated with Excessive daytime sleepiness among type 2 diabetes mellitus patients. …”
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Cohort profile: the Viral load Cohort North-East Lesotho (VICONEL) from 2016 to 2023 – cohort description, test volumes, predictors of viraemia and the road ahead by Tracy Glass, Frédérique Chammartin, Jochen Ehmer, Thomas Klimkait, Alain Amstutz, Josephine Muhairwe, Irene Ayakaka, Blaise Lukau, Jennifer Anne Brown, Lipontso Motaboli, Malebanye Lerotholi, Maurus Kohler, Kathrin Haenggi, Moliehi Mokete, Makobefo Gladys Chakela, Mpho Kao, Mathebe Kopo, Moleboheng Mokebe, Lorena Urda, Bienvenu Lengo Nsakala, Anna Klicpera, Nadine Tschumi, Niklaus Daniel Labhardt

“…Sex, age category/ART regimen core agent (combined variable), time since ART initiation and district were independently associated with viraemia.Future plans VICONEL offers potential for (1) further digitalisation and automation of results sharing at the client, facility and district/national level, (2) integration of additional clinical and diagnostic data, including comorbidities and drug resistance and (3) embedding randomised trials.…”
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Cardiac Abnormalities in Acromegaly Patients: A Cardiac Magnetic Resonance Study by Xiaopeng Guo, Jian Cao, Peijun Liu, Yihan Cao, Xiao Li, Lu Gao, Zihao Wang, Ligang Fang, Zhengyu Jin, Yining Wang, Bing Xing

“…Cardiac abnormalities are the most common and deadly comorbidities of acromegaly. Assessments using cardiac magnetic resonance (CMR) imaging in acromegaly patients are rare. …”
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Social determinants of financial stress and association with psychological distress among young adults 18–26 years in the United States by Anaiya Nasir, Umair Javed, Kobina Hagan, Ryan Chang, Harun Kundi, Zahir Amin, Sara Butt, Sadeer Al-Kindi, Sadeer Al-Kindi, Zulqarnain Javed, Zulqarnain Javed

“…Female, non-Hispanic Black and Hispanic, low income/low education, uninsured, non-citizen and comorbidities were associated with high FS burden. In fully adjusted models, high FS was associated with over 6-fold (OR = 6.17, 95% CI 4.43–8.61) higher risk of high PD.DiscussionOne in six young adults in the US experiences high FS, which portends high risk of PD. …”
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Nasopharyngeal carriage of Staphylococcus aureus in a rural population, Sierra Leone by Lisa Maria Kleine, Emmanuel Marx Kanu, Tobias Grebe, Desmond Mohamed Sesay, Henning Loismann, Maxwell Sesay, Tom Theiler, Viktoria Rudolf, Alexander Mellmann, Laura C. Kalkman, Martin P. Grobusch, Frieder Schaumburg

“…Except for past use of antimicrobials (p = 0.019), no specific risk factors such as comorbidities including hemoglobin variants were associated with S. aureus nasopharyngeal colonization. …”
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Association between fasting blood glucose and psychotic symptoms in Chinese patients with first-episode drug-naïve major depressive disorder by Xingzhi Xia, Hanxu Deng, Wei Ren, Lin Yang, Yingzhao Zhu, Yaozhi Liu, Junjun Liu, Xueli Zhao, Fengnan Jia, Xiangdong Du, Xiangyang Zhang

“…Additionally, interaction and stratified analyses were performed based on gender, educational background, marital status, presence of comorbid anxiety, and history of suicide attempt. Results Multivariate logistic regression analysis showed that FBG was positively associated with the risk of PD in FEDN MDD patients (OR = 1.68, 95% CI: 1.31 to 2.13; P < 0.05). …”
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The Characteristics of Self-Reported Symptomatic by Individuals with Mild COVID-19 during Omicron Pandemic in China: Cross-Sectional Online Survey by Xiang Liu, Xiaoling Wei, Xiangju Xing, Ling Lu, Min Chen, Yumei Zhao, Shuang Zhou, Ting Feng, Li Wang, Chengling Luo, Jing Xia, Jun Zhang, Banghong Liao, Kui Wu, Wei Yao, Changzheng Wang

“…In addition, women experienced a significantly higher prevalence of symptoms than men, but there was no significant difference in the severity of most symptoms. The presence of comorbidities did not increase the incidence or severity of symptoms in those with mildly infected individuals. …”
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