Complications after endoscopic spine surgery - risk factors and preventive strategies by Joanna Olszak, Karolina Zalewa, Lidia Bartoszek, Dominika Orłowska, Wojciech Kapłan, Mikołaj Poleszczuk, Karol Poleszczuk, Alicja Milewska, Anna Czuba

“…Patient factors include age, comorbidities, and anatomical abnormalities of the spine. …”
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Advancing allergic rhinitis research through phenome-wide association studies: Insights from known genetic loci by Xingling Tan, MD, Zhouyouyou Xiao, MB, Yao Wen, MD, Han Liu, MD, Wei Yu, MD

“…Although genetic risk loci associated with AR have been reported, the connections between these loci and AR comorbidities or other diseases remain unclear. Methods: This study conducted a phenome-wide association study (PheWAS) using known AR risk loci to explore the impact of known AR risk variants on a broad spectrum of phenotypes. …”
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Association of Depression with Uncontrolled Hypertension in Primary Care Setting: A Cross-Sectional Study in Less-Developed Northwest China by Lin Wang, Nanfang Li, Mulalibieke Heizhati, Mei Li, Zhikang Yang, Zhongrong Wang, Reyila Abudereyimu

“…Hypertensive patients commonly experience comorbid depression, which is closely associated with adverse health outcomes. …”
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Relation of left atrial overload indices with prognostic endpoints in heart failure and preserved ejection fraction by Shiro Hoshida, Koichi Tachibana, Yukinori Shinoda, Tomoko Minamisaka, Masahiro Seo, Masamichi Yano, Takaharu Hayashi, Akito Nakagawa, Yusuke Nakagawa, Shunsuke Tamaki, Takahisa Yamada, Yoshio Yasumura, Yohei Sotomi, Shungo Hikoso, Daisaku Nakatani, Yasushi Sakata, OCVC‐Heart Failure Investigators

“…Stroke volume (SV)/left atrial volume (LAV), an index for LA volume overload, was a significant prognostic factor of re‐admission for heart failure in the multivariable Cox hazard analysis adjusted for comorbidities [hazard ratio (HR) 0.616, 95% confidence interval (CI) 0.430–0.882, P = 0.008]. …”
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The Silent Threat of Human Metapneumovirus: Clinical Challenges and Diagnostic Insights from a Severe Pneumonia Case by Rubens Carmo Costa-Filho, Felipe Saddy, João Luiz Ferreira Costa, Leandro Reis Tavares, Hugo Caire Castro Faria Neto

“…Methods: This case report describes a 68-year-old male who developed severe community-acquired pneumonia (CAP) caused by hMPV despite being immunocompetent and having no significant comorbidities. The diagnosis was confirmed via multiplex RT-PCR, excluding bacterial and viral coinfections. …”
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SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection by Richard C. Crist, Samar N. Chehimi, Saurabh S. Divakaran, Michael J. Montague, Sébastien Tremblay, Noah Snyder-Mackler, Martin O. Bohlen, Kenneth L. Chiou, Trish M. Zintel, Cayo Biobank Research Unit, Michael L. Platt, Halvor Juul, Guido Silvestri, Matthew R. Hayes, Dennis L. Kolson, Benjamin C. Reiner

“…Abstract Understanding the neurobiological mechanisms underlying HIV-associated neurocognitive decline in people living with HIV is frequently complicated by an inability to analyze changes across the course of the infection and frequent presence of comorbid psychiatric and substance use disorders. Preclinical non-human primate simian immunodeficiency virus (SIV) models help address these shortcomings. …”
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Serum sodium to chloride ratio and mortality on continuous ambulatory peritoneal dialysis: a multicenter retrospective study by Jiayin You, Sijie Gu, Ning Su, Xiaoran Feng, Fenfen Peng, Qingdong Xu, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Na Tian, Xianfeng Wu, Niansong Wang

“…Following adjustments for comorbidities and multiple covariates, individuals in the highest Na/Cl quartile (>1.42) exhibited lower all‐cause mortality (hazard ratio [HR] 0.63, 95% confidence interval [CI] 0.47–0.86) and cardiovascular mortality (HR 0.38, 95% CI 0.22–0.67) compared with those in the lowest quartile (<1.33). …”
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Association between platelet count and 30-day in-hospital mortality among intensive care unit patients with sepsis: a multicenter retrospective cohort study by Jun Wang, Pan Zhou, Xin Li, Li Zhou, Zhe Deng

“…Analyses were adjusted for demographics, clinical parameters, comorbidities, and treatments. Generalized additive models and two-piecewise linear regression were used to assess the relationship between platelet count and mortality.ResultsA U-shaped relationship was identified with an inflection point at 176 × 10⁹/L. …”
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Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes by Chinonso A. Nwakama, Romain Durand-de Cuttoli, Zainab M. Oketokoun, Samantha O. Brown, Jillian E. Haller, Adriana Méndez, Mohammad Jodeiri Farshbaf, Y. Zoe Cho, Sanjana Ahmed, Sophia Leng, Jessica L. Ables, Brian M. Sweis

“…These findings suggest that complex relationships between metabolic dysfunction and dissociable valuation algorithms underlying unique cognitive heuristics and sensitivity to opportunity costs can disrupt distinct computational processes leading to comorbid psychiatric vulnerabilities.…”
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Impact of Coronary Artery Disease and Diabetes Mellitus on the Long-Term Follow-Up in Patients after Retrograde Recanalization of the Femoropopliteal Arterial Region by Joanna Wojtasik-Bakalarz, Zoltan Ruzsa, Tomasz Rakowski, Andreas Nyerges, Krzysztof Bartuś, Agata Stanek, Dariusz Dudek, Andrzej Surdacki, Paweł Kleczyński, Stanisław Bartuś

“…The most relevant comorbidities in patients with peripheral artery disease (PAD) are coronary artery disease (CAD) and diabetes mellitus (DM). …”
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Impact of Obesity-Associated SARS-CoV-2 Mutations on COVID-19 Severity and Clinical Outcomes by Ana B. Martínez-Martinez, Alexander Tristancho-Baró, Beatriz Garcia-Rodriguez, Marina Clavel-Millan, Maria Pilar Palacian, Ana Milagro, Antonio Rezusta, Jose M. Arbones-Mainar

“…These results emphasize the importance of studying mutations within the broader context of comorbidities, other mutations, and regional factors to enhance our understanding of SARS-CoV-2 adaptation in high-risk groups. …”
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Environmental Pollutants as Emerging Concerns for Cardiac Diseases: A Review on Their Impacts on Cardiac Health by Vinay Kumar, Hemavathy S, Lohith Kumar Dasarahally Huligowda, Mridul Umesh, Pritha Chakraborty, Basheer Thazeem, Anand Prakash Singh

“…Comorbidities related to cardiovascular disease (CVD) and environmental pollution have emerged as serious concerns. …”
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Associations of personality traits with actigraphic sleep in middle-aged and older adults by Jill A. Rabinowitz, Yijun Zhou, Diefei Chen, Yiwei Yue, Darlynn M. Rojo-Wissar, Yang An, Sarah Wanigatunga, Jennifer A. Schrack, Vadim Zipunnikov, Eleanor M. Simonsick, Antonio Terracciano, Paul T. Costa, Luigi Ferrucci, Adam P. Spira

“…Adjusting for age, sex, race, education, depressive symptoms, comorbidities and interactions of these variables with time, greater extraversion was associated with higher sleep efficiency. …”
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Depression Increases Stroke Hospitalization Cost: An Analysis of 17,010 Stroke Patients in 2008 by Race and Gender by Baqar Husaini, Robert Levine, Linda Sharp, Van Cain, Meggan Novotny, Pamela Hull, Gail Orum, Zahid Samad, Uchechukwu Sampson, Majaz Moonis

“…Higher stroke cost among blacks may reflect the impact of comorbidities and the delay in care of serious health conditions. …”
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Early Efficacy of In Situ Fenestration with a Triple Chimney Technique for High-Risk Stanford Type A Aortic Dissection: A Single-Center Retrospective Study by Qingsong Wu, Heng Lu, Debin Jiang, Zhihuang Qiu, Javed Rashid, Linfeng Xie, Yue Shen, Liangwan Chen

“…This study included 24 patients who were treated by in situ fenestration with TCT for high-risk TAAD between January 2018 and December 2019. Multiple comorbidities or preoperative critical conditions rendered patients ineligible for open surgery, but all patients that were evaluated and considered had to undergo operation. …”
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Diastasis of Symphysis Pubis In 18-Years Old Female Patient Treated With Conservative Pelvic Binder: Case Report by Trisna Angga Basudana, Mifta Nurmalasari, Austana Nur Hafizh, Muhammad Hanun Mahyuddin

“…Considering the patient's young age and no comorbidities, it was assumed that the healing process would occur quickly, so conservative treatment was chosen first. …”
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Clinical Manifestations Associated with Overweight/Obesity in Puerto Ricans with Fibromyalgia Syndrome by Ruth M. Fred-Jiménez, Mariangelí Arroyo-Ávila, Ángel M. Mayor, Grissel Ríos, Luis M. Vilá

“…Sociodemographic features, FMS-related symptoms, tender points (per ACR criteria), comorbidities, and FMS treatment were examined. BMI was calculated and patients were grouped into two categories: BMI ≤ 24.9 kg/m2 (nonoverweight/obese) and BMI ≥ 25 kg/m2 (overweight/obese). …”
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Characterizing the medical and social complexity experienced by Inuit children and their families from Nunavut who access care at an urban Canadian tertiary level paediatric hospit... by Yipeng Ge, Amanda Mills, Victoria McCann, Sara Trincao-Batra, Deepti Reddy, Dennis Newhook, Richard J. Webster, Stephanie Sutherland, Melissa Weber, Radha Jetty

“…They had a median (IQR) of 12.5 (7.8, 18.0) comorbidities, 11 (8.0, 14.2) healthcare services accessed and 3 (2, 5) medications. …”
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Anatomical, functional, and blood-born predictors of severity of brachycephalic obstructive airway syndrome severity in French Bulldogs by Claudia Schmid, Claudia Schmid, Claudia Schmid, Aline R. Steiner, Léonie Spielhofer, Léonie Spielhofer, Meltem Galfetti, Meltem Galfetti, Nikki Rentsch, Nikolay Bogdanov, Johannes Vogel, Regina Hofmann-Lehmann, Regina Hofmann-Lehmann, Sonja Hartnack, Georgy Astakhov, Reinhard Furrer, Anna Bogdanova, Anna Bogdanova, Iris Margaret Reichler

“…Brachycephalic breeds suffer from respiratory distress known as brachycephalic obstructive airway syndrome (BOAS) and the multiple comorbidities associated with it. Targeted breeding toward a more BOAS-free phenotype requires accurate and least invasive detection of BOAS severity grades that are accessible and accepted by the breeders and kennel clubs. …”
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Red Blood Cell Distribution Width Predicts Pulmonary Hypertension Secondary to Chronic Obstructive Pulmonary Disease by Jie Yang, Chuanmei Liu, Lingling Li, Xiongwen Tu, Zhiwei Lu

“…Clinical data including demographic characteristics, comorbidities, and results of ultrasound scans, imaging examinations, and laboratory tests were recorded. …”
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