Efficacy of Anakinra for Various Types of Crystal-Induced Arthritis in Complex Hospitalized Patients: A Case Series and Review of the Literature by A. Aouba, S. Deshayes, L. Frenzel, A. Decottignies, C. Pressiat, B. Bienvenu, F. Boue, G. Damaj, O. Hermine, S. Georgin-Lavialle

“…We retrospectively analyzed the outcome of six patients affected with subacute crystal-induced arthritis who had received anakinra in second or third line therapy, including three patients with crowned dens syndrome and three others with gouty arthritis. Patients’ comorbidities, reasons for anakinra use and associated drugs, and outcomes were recorded. …”
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Hikikomori, a risk factor for life-threatening malnutrition: a case report of an emergency within the vulnerability by Nicola Artusi, Emanuele Russo, Gianmaria Valeri, Marzia Tecchiolli, Franco Cominotto

“…Hikikomori  syndrome  can  be  especially  dangerous  when  compounded  by  psychiatric  comorbidities  or  socioeconomic  vulnerabilities,  [2],  as  evidenced  by  an  alarming  increase  during  the  COVID-19  pandemic. …”
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Liver Transplantation in Alcohol-Associated Hepatitis. Benefits and Limitations of Psychosocial Selection and Support in Alcohol Relapse. The Experience of a Tertiary Center in Ita... by Luca S. Belli, Adelaide Panariello, Giovanni Perricone, Paola Prandoni, Raffaella Viganò, Chiara Mazzarelli, Chiara Becchetti, Sara Giacalone, Giovanna Donvito, Sara Conti, Paolo A. Cortesi, Elena Roselli, Gianpaola Monti, Marco Carbone, Luciano G. De Carlis, Luciano G. De Carlis, Mauro Percudani

“…From this experience emerged that psychiatric comorbidities are highly prevalent among patients with SAH and that their diagnosis/treatment contributed to mitigate the risk of alcohol relapse.…”
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Clinical Features and Rehabilitation Needs in Patients with Neuroinvasive West Nile Virus Infection: A Retrospective Analysis in an Area of High Incidence by Maria Chiara Maccarone, Francesco Piccione, Marina Munari, Noemi Faccin, Gianluca Regazzo, Luisa Barzon, Stefano Masiero

“…Data included demographics, comorbidities, length of hospital stay, days at PMR evaluation, and rehabilitation duration until discharge or death, alongside objective examination findings and Barthel Index scores. …”
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Healthcare access, attitudes and behaviours among Navajo adults during the COVID-19 pandemic: a cross-sectional study by Robin B Harris, Carmenlita Chief, Heidi E Brown, Rachelle L Begay, Priscilla R Sanderson, Breanna Lameman

“…Discussion themes revealed perceived disruptions of healthcare needs with acknowledgement that healthcare providers were supportive throughout the Navajo Nation quarantine.Conclusion Presence of comorbidities and living in multigenerational homes do not explain the disproportionate effects of COVID-19 among American Indian communities. …”
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Association between parity and gravidity & hypertension and blood pressure: protocol for a systematic review and meta-analysis by Sofia B Ahmed, Sonia Butalia, Magali Robert, Tyrone G Harrison, Sandra M Dumanski, Nabilah Gulamhusein, Badal S B Pattar, Jane A Schulz

“…Extracted data will include study and population characteristics, comorbidities, parity, gravidity, incidence of hypertension and changes in blood pressure, study quality and risk of bias. …”
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Role of Lipotoxicity and Contribution of the Renin-Angiotensin System in the Development of Polycystic Ovary Syndrome by Alexandre Connolly, Samuel Leblanc, Jean-Patrice Baillargeon

“…Polycystic ovary syndrome (PCOS) is a common and significant condition associated with hyperandrogenism, infertility, low quality of life, and metabolic comorbidities. One possible explanation of PCOS development is cellular dysfunction induced by nonesterified fatty acids (NEFAs), that is, lipotoxicity, which could explain both the hyperandrogenemia and insulin resistance that characterize women with PCOS. …”
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Muscle Strength, Physical Activity, and Functional Limitations in Older Adults with Central Obesity by Cassandra M. Germain, John A. Batsis, Elizabeth Vasquez, Douglas R. McQuoid

“…Logistic models were adjusted for age, education, comorbidities, and body-mass index and weighted. Results. …”
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Surviving prematurity: retrospective longitudinal study of multisystem consequences in preterm-born individuals from infancy to adolescence by Ruta Morkuniene, Ruta Levuliene, Vilmantas Gegzna, Egle Marija Jakimaviciene, Janina Tutkuviene

“…Conclusions The highest disease burden for preterm-born individuals occurred by age 7, with lower BW linked to greater health complexity and unique comorbidities.…”
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Impact of post-traumatic stress disorder on epileptogenic networks: a functional connectivity study by Lisa-Dounia Soncin, Sara Simula, Nicolas Hemmer, Hélène Mourre, Marie Arthuis, Julia Makhalova, Christian Benar, Sylvane Faure, Fabrice Bartolomei

“…Our study is the first to offer insights into the intricate dynamic linking PTSD and epilepsy and highlights the need for accounting for the influence of comorbidities on epileptogenic networks.…”
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Preclinical Evidences for an Antimanic Effect of Carvedilol by Greicy Coelho de Souza, Julia Ariana de S. Gomes, Ana Isabelle de Góis Queiroz, Maíra Morais de Araújo, Lígia Menezes Cavalcante, Michel de Jesus Souza Machado, Aline Santos Monte, David Freitas de Lucena, João Quevedo, André Ferrer Carvalho, Danielle Macêdo

“…Oxidative imbalance, alterations in brain-derived neurotrophic factor (BDNF), and mitochondrial dysfunction are implicated in bipolar disorder (BD) pathophysiology and comorbidities, for example, cardiovascular conditions. …”
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Stroke in Athletes with Atrial Fibrillation: A Narrative Review by Joana Certo Pereira, Maria Rita Lima, Francisco Moscoso Costa, Daniel A. Gomes, Sérgio Maltês, Gonçalo Cunha, Hélder Dores, Pedro Adragão

“…However, their stroke risk remains uncertain due to their younger age, higher cardiovascular fitness, and lower rate of comorbidities. Several key studies highlight that AF may increase the risk of stroke in endurance athletes, particularly those over 65. …”
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Risk Factors of Lymph Edema in Breast Cancer Patients by Haghighat Shahpar, Akbari Atieh, Ansari Maryam, Homaei Shandiz Fatemeh, Najafi Massoome, Ebrahimi Mandana, Yunesian Masud, Mirzaei Hamid Reza, Akbari Mohammad Esmaeil

“…Variables such as low educational level, body mass index (BMI), higher stage of disease, number of involved lymph nodes, comorbid diseases, trauma, infection, and the time after surgery showed significant correlation with the development of lymphedema. …”
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Physical activity in patients after bariatric surgery - a literature review by Martyna Śliwińska, Anna Podraza, Małgorzata Wirkijowska, Jakub Wirkijowski, Katarzyna Wójtowicz, Agata Walczak, Wiktoria Gajek-Flanczewska, Sebastian Flanczewski, Paulina Woźniak, Ewa Wietrzykowska, Dominika Sobolewska, Katarzyna Michalczyk-Fraszka

“… Introduction: Obesity is a growing global health concern, leading to severe comorbidities such as cardiovascular disease, diabetes, and depression. …”
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Ultrasound-Guided Multiple Peripheral Nerve Blocks in a Superobese Patient by Alper Kilicaslan, Ahmet Topal, Atilla Erol, Hale Borazan, Onur Bilge, Seref Otelcioglu

“…Morbid obesity is associated with an increased incidence of medical comorbidities and restricts the application choices in anesthesiology. …”
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Risk of Microvascular Complications and Macrovascular Risk Factors in Early-Onset Type 1 Diabetes after at Least 10 Years Duration: An Analysis of Three Population-Based Cross-Sect... by Thaddäus Tönnies, Anna Stahl-Pehe, Christina Baechle, Katty Castillo, Oliver Kuss, Rhuphine Yossa, Lena M. E. Lindner, Reinhard W. Holl, Joachim Rosenbauer

“…In early-onset type 1 diabetes, there exists a considerable risk of complications and comorbidities already in young ages. Future research should focus on prevention of diabetic complications in young patients and clarification of pathways of the associations found.…”
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Phenome-wide association network demonstrates close connection with individual disease trajectories from the HUNT study. by Martina Hall, Marit K Skinderhaug, Eivind Almaas

“…The HUNT sub-PheNet showing both genetically and co-observed diseases offers an interesting framework to study groups of diseases and examine if they, in fact, are comorbidities. We find that the HUNT sub-PheNet offers the possibility to pinpoint exactly which mutation(s) constitute shared cause of the diseases. …”
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Analysis of the risk of early postoperative complications after Bentall procedure by V.A. Tymoshenko, B.M. Todurov

“…Patients with prolonged stay in intensive care unit were characterized by significantly older age (p = 0.005), more frequent presence of comorbidities of arterial hypertension (p = 0.044) and significantly lower initial values of glomerular filtration rate (p = 0.045). …”
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Sex Differences in Lung Cancer Characteristics at Diagnosis: A Nationwide Register‐Based Study From the Faroe Islands (2015–2020) by Annika H. Lindenskov, Halla Potts, Marnar F. Kristiansen, Maria S. Petersen, Marin Strøm

“…Data on age, sex, civil status, cancer type, stage, smoking history, comorbidities, and performance status were extracted from electronic patient records. …”
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Characterization of the Care Process for Hypertensive People in a Polyclinic in Old Havana by Addys Díaz Piñera, Yamila Soler Carbonell, Nelsy Álvarez Mesa, Armando Rodríguez Salvá

“…The most frequent comorbidities were: diabetes mellitus with 21.4 % and chronic obstructive pulmonary disease and asthma in 9.4 %. 54.7 % of these people did not feel the need for care in the last year and only 45.3 % were seen in a follow-up consultation. 81.8 % had not had their blood pressure measured for more than a year, 89.3 % had indicated drug treatment, 86.2 % were controlled and 74.6 % adhered to the treatment. …”
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