Intraoperative Management of Large Resuscitation-Associated Venous Air Embolism (VAE) for Emergent Neurological Surgery by Ryan S. D’Souza, Arnoley S. Abcejo, Matthew A. Sexton

“…Given her age, lack of preexisting cardiac comorbidities, hemodynamic stability, and critical cerebral herniation risk, further cardiac evaluation was deferred, and the patient was transferred to the operating room for emergent decompressive craniotomy. …”
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Hidradenitis Suppurativa in Kuala Lumpur, Malaysia: A 7-Year Retrospective Review by Moonyza Akmal Ahmad Kamil, Azura Mohd Affandi

“…A prompt recognition of HS is imperative, to screen for comorbidities and to initiate early treatment to reduce physical and psychological complications.…”
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Exploring mechanisms of insulin action and strategies to treat diabetes by Takayoshi Sasako

“…In the liver, insulin regulates endoplasmic reticulum (ER) stress response during feeding, whereas ER stress ‘response failure’ contributes to the development of steatohepatitis comorbid with diabetes. Not only the liver but also the proximal tubules of the kidney are important in the regulation of gluconeogenesis, and we revealed that insulin suppresses gluconeogenesis in accordance with absorbed glucose in the latter tissue. …”
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Renal Autotransplantation for Iatrogenic High-Grade Ureteric Stricture by Jose Soto Soto, Michael Phillips, Joseph Cernigliaro, William Haley

“…This was deferred, due to concern for progressive kidney failure associated with her comorbidities. A radionuclide Tc-99m MAG3 renal scan revealed differential perfusion as follows: 44% left kidney and 56% right kidney, with symmetrical uptake on the renogram phase and delayed excretion on the left, which were correctted following furosemide administration. …”
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Spontaneous Evisceration, or “Burst Abdomen,” in Patient with Prior Flood Syndrome Surgical Repair by Matthias Barden, Dustin Marinelli, Kirsten Cable

“…This patient likely suffered from delayed burst abdomen due to multiple comorbidities and postoperative complications.…”
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The Dynamics of the Relationship between Attention Deficit Hyperactivity Disorder and Alcohol Use Disorder by Sevda Acar, Yeliz Aktaş

“…Combining pharmacological and non- pharmacological interventions is crucial for enhancing patients’ quality of life and alleviating the impact of comorbid conditions. Early diagnosis and intervention play a pivotal role in the effective management of these disorders. …”
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Prevalence of reading difficulties and attention deficit hyperactivity disorder in a sample of Spanish prisoners by Almudena Giménez, Mariana Loredo, Blanca Monge, Pablo Sánchez, Javier López-Pérez

“…Finally, 67% of prisoners with poor reading, low phonological skills, or declared dyslexic exhibited comorbid symptoms of ADHD. This is taken as evidence that dyslexia itself may not be directly linked to involvement in antisocial behavior, but in combination with other conditions. …”
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A Review of Risk Factors and Predictors for Hemorrhagic Transformation in Patients with Acute Ischemic Stroke by Sneha E. Thomas, Noorine Plumber, Priyanka Venkatapathappa, Vasavi Gorantla

“…This review summarises how specific risk factors such as demographic factors like age, gender, and race/ethnicity, comorbidities including essential hypertension, atrial fibrillation, diabetes mellitus, congestive heart failure, and ischemic heart disease along with predictors like higher NIHSS score, larger infarction size, cardioembolic strokes, systolic blood pressure/pulse pressure variability, higher plasma glucose levels, and higher body temperature during ischemic event, lower low-density lipoprotein and total cholesterol, early ischemic changes on imaging modalities, and some rare causes make an individual more susceptible to developing HT. …”
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Survival Analysis of Diabetic Colorectal Cancer Patients on Metformin by Alex Brandon Wong, Ravi Patnaik, Li Ling Chaw, Shir Kiong Lu, Long Chiau Ming, Wen Han Chooi, Ya Chee Lim

“…Kaplan-Meier and multivariate Cox proportional hazard regression models were used to analyze the data, construct survival curves, and adjust for comorbidities. Of a total of 112 diabetic patients, 79 patients (70.5%) were on metformin, and 33 patients (29.5%) were on other antihyperglycemic medications. …”
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Retinopathy in Metabolic Dysfunction-Associated Steatotic Liver Disease by Myrsini Orfanidou, Stergios A. Polyzos

“…., influencing various organ systems beyond the liver and, thus, contributing to comorbidities. Characterized by excessive fat accumulation in the hepatocytes, MASLD is frequently linked to metabolic syndrome components, such as obesity, insulin resistance, dyslipidemia, and hypertension. …”
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Thrombosed Fetal Dural Sinus Malformation: A Case Report by Tayseer Al Muteri, Muna Al Rawahi, Felipe Moretti

“…Case Description: A 25-year-old woman, primigravida, with no comorbidities at 20 weeks and 1 day, underwent a detailed ultrasound followed by MRI. …”
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Are we Really Improving the Quality of Life after Hemiarthroplasty of the Hip in the Elderly? An Observational Study by T. Adarsh, Mruthyunjaya, C. S. Likhit, Nawab Akthar Khan

“…Conclusion: Results showed the need for improvisation of various aspects of postoperative care such as designated rehabilitation protocols, fall clinics, psychotherapy and relaxation, and geriatric care for associated comorbidities. Implementing such a comprehensive specialty care approach along with good surgery will improve the QOL to presurgical level.…”
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Medicine Dose Adjustment Practice and Associated Factors among Renally Impaired Patients in Amhara Regional State, Ethiopia by Tirsit Kestela Zeleke, Tilahun Yemanu Birhan, Ousman Abubeker Abdela

“…Number of medicines, number of comorbidities, and being unemployed were significantly associated with inappropriate dose adjustment. …”
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Is Less Surgical Treatment Possible in the Treatment of Degenerative Spine Diseases? Four-Year Follow-up Results of Foraminal Epidural and Facet Joint Injection Treatments by Yunus Kaçar, Derya Karaoğlu Gündoğdu

“…Aim The study aims to examine the long-term outcomes of foraminal epidural injection and facet joint injection therapies in patients over the age of 60 who have been recommended for surgical intervention for degenerative spinal diseases but have declined surgical treatment due to comorbidities, anesthesia risks, and surgical risks. …”
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A 16-Year-Old Male with Thoracic Compression following Posterior Spinal Instrumentation and Fusion for Marfan-Associated Syndromic Scoliosis by Mason Uvodich, Ross Barman, Adam Reitz, Matthew Sexton

“…Given the expansive phenotypic variations and comorbidities associated with Marfan syndrome, knowledge of perioperative risk factors and potential complications is essential. …”
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Atrial fibrillation and cognitive impairment: mechanisms, influencing factors, and prospects by Li-Juan Huang, Jian-Shu Chen, Yu-Zhe Song, Peng Chang

“…This high incidence of cognitive decline in AF patients may result from various mechanisms, including reduced cerebral perfusion, microembolism, decreased cardiac output, and chronic inflammation.MethodsThis review synthesizes current evidence on the relationship between AF and cognitive impairment, examines underlying mechanisms of cognitive decline in AF, and explores the roles of AF type, treatment approaches, left atrial characteristics, and associated conditions in cognitive function outcomes.ResultsCognitive outcomes in AF are further influenced by a range of factors, such as left atrial structural parameters, AF type and duration, anticoagulation use, catheter ablation, comorbidities, age, and gender.DiscussionThe review highlights the complex interplay between AF and cognitive impairment, emphasizing the importance of understanding the various mechanisms and factors that contribute to cognitive decline in AF patients. …”
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Comparison of Risks Factors for Unplanned ICU Transfer after ED Admission in Patients with Infections and Those without Infections by Jeffrey Che-Hung Tsai, Ching-Wan Cheng, Shao-Jen Weng, Chin-Yin Huang, David Hung-Tsang Yen, Hsiu-Ling Chen

“…These common risk factors included specific comorbidities, physiological responses, organ dysfunctions, and other serious symptoms and signs. …”
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Protective Role of Platelets in Myocardial Infarction and Ischemia/Reperfusion Injury by Kornela Hałucha, Alina Rak-Pasikowska, Iwona Bil-Lula

“…Additionally, the use of platelet-derived microparticles as possible markers of MI, with and without comorbidities, and their role in cardioprotection are discussed. …”
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Tumor Necrosis Factor-α and Interleukin-6: Potential Interorgan Inflammatory Mediators Contributing to Destructive Periodontal Disease in Obesity or Metabolic Syndrome by Roozbeh Khosravi, Khady Ka, Ting Huang, Saeed Khalili, Bich Hong Nguyen, Belinda Nicolau, Simon D. Tran

“…Obesity has been associated with increased comorbidities, such as coronary artery disease, diabetes, and destructive periodontal disease. …”
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Brain Oxygenation During Exercise in Different Types of Chronic Lung Disease: A Narrative Review by Stella Kritikou, Andreas Zafeiridis, Georgia Pitsiou, Ioannis Gkalgkouranas, Leonidas Kastritseas, Afroditi Boutou, Konstantina Dipla

“…These differences depend on the specific pathophysiology of the lung disease and the presence of comorbidities. Notably, reduced cerebral oxygenation during exercise in fibrotic-ILD has been linked with the development of dyspnea and early exercise termination. …”
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