Immune aging and infectious diseases by Ruochan Chen, Ju Zou, Jiawang Chen, Ling Wang, Rui Kang, Daolin Tang, Sihan Zhou, Xiuyuan Hao

“…Cellular senescence exacerbates these issues by releasing pro-inflammatory factors, further perpetuating chronic inflammation. Moreover, comorbidities, such as cardiovascular disease and diabetes, which are common in older adults, amplify immune dysfunction, while immunosuppressive medications further complicate responses to infections. …”
Get full text

Esophageal Intramural Pseudodiverticulosis: A Rare Endoscopic Finding by Luciana Lopes de Oliveira, Fred Olavo Aragão Andrade Carneiro, Elisa Ryoka Baba, Thiago Guimarães Vilaça, Dalton Marques Chaves, Everson Luiz de Almeida Artifon, Eduardo Guimarães Hourneaux de Moura, Paulo Sakai

“…This was a typical endoscopic finding of esophageal intramural pseudodiverticulosis, a benign and rare condition, related to chronic esophagitis and others comorbid states, such as gastroesophageal reflux disease or infectious esophagitis, diabetes mellitus, alcohol consumption, and achalasia. …”
Get full text

Diagnosis of Dilated Cardiomyopathy: Patient Reaction and Adaptation—Case Study and Review of the Literature by Solomis Solomou, Maria Stavrou, Justin Marley

“…Depression is a common comorbid condition in patients with heart failure. …”
Get full text

Pathologic complete response following low-dose radiation for advanced oral cavity cancer in a patient with human immunodeficiency virus by Amy B. Leming, Andrea L. Johnston, Greg A. Krempl, Evan J. Fowle, Daniel J. Morton, Christina E. Henson

“…Abstract Background Advanced squamous cell carcinoma (SCCa) of the oral cavity is often not amenable to curative-intent therapy due to tumor location, tumor size, or comorbidities. Case presentation A 51-year-old male patient with human immunodeficiency virus and on highly active antiretroviral therapy (HAART) presented with a cT4aN2c SCCa of the tongue. …”
Get full text

Myelodysplastic Syndrome with Transfusion Dependence Treated with Venetoclax by Waqas Jehangir, Alexander Karabachev, Taimoor Jahangir, Elvira Umyarova

“…Hematopoietic cell transplantation is potentially the only curative option; however, treatment is often unavailable due to age and comorbidities. Hypomethylating agents, azacitidine and decitabine, and the immunomodulatory agent, lenalidomide, are the only FDA approved medications for the treatment of MDS, all of which are noncurative. …”
Get full text

The connection between climate change and perinatal mental health by Jennifer L. Barkin, Jennifer L. Barkin, Sanne van Rhijn, Sanne van Rhijn, Chloe M. Johnson

“…Mood and anxiety disorders are among the leading comorbidities during pregnancy and the postpartum period, and they are associated with significant familial and societal burdens. …”
Get full text

Comparative Quality of Laparoscopic and Open Cholecystectomy in the Elderly Using Propensity Score Matching Analysis by Kazuaki Kuwabara, Shinya Matsuda, Koichi Benjamin Ishikawa, Hiromasa Horiguchi, Kenji Fujimori

“…The demographics, cholecystitis severity, comorbidities, complications, and admission and discharge Barthel Index (BI) scores of patients with benign gallbladder diseases were analyzed. …”
Get full text

Convalescence. Some comments about COVID-19 by Alfredo Darío Espinosa Brito, Alfredo Alberto Espinosa Roca

“…It insists on the factors that can influence convalescence: the characteristics of each person (biological, psychological, social, cultural and spiritual); the "state of seriousness" that the patient had in the acute phase of the disease and whether there was a need for admission to intensive care; adverse effects of medications and other procedures carried out during care and comorbidities.…”
Get full text

Reviewing the current treatment approaches for bullous pemphigoid – analysis of literature by Julia Nowak, Agnieszka Najdek, Daria Oleksy, Dawid Komada, Urszula Kaczmarska, Aleksandra Woźniak, Michał Jakub Cioch, Marcin Mycyk, Kamil Hermanowicz, Katarzyna Doman

“…BP significantly impacts patients’ quality of life due to painful, pruritic skin lesions and is associated with a higher prevalence of psychiatric comorbidities, such as schizophrenia. BP increases the risk of complications, including pulmonary embolism and pneumonia, and is linked to high mortality. …”
Get full text

Intramuscular Adipose Tissue, Sarcopenia, and Mobility Function in Older Individuals by Robin L. Marcus, Odessa Addison, Leland E. Dibble, K. Bo Foreman, Glen Morrell, Paul LaStayo

“…Method. 109 older adults with a variety of comorbid disease conditions were examined for thigh muscle composition via MRI, knee extensor strength via isometric dynamometry, and mobility function. …”
Get full text

Pertussis Vaccination for Adults: An Updated Guide for Clinicians by Kay Choong See

“…Although traditionally associated with children, pertussis is increasingly prevalent among adults, particularly those with comorbidities or weakened immune systems, where it can lead to severe complications. …”
Get full text

Epidemiological and Pathogenic Relationship between Sleep Apnea and Ischemic Heart Disease by Carlos Carpio, Rodolfo Álvarez-Sala, Francisco García-Río

“…Moreover, chronic intermittent hypoxia and oxidative stress have an important role in the pathogenesis of coronary disease and are also fundamental to the development of atherosclerosis and other comorbidities present in coronary artery diseases such as lipid metabolic disorders. …”
Get full text

An approach to a geropsychiatric assessment by Sandeep Grover, Ajit Avasthi

“…This involves understanding the signs and symptoms [S], Additional Diagnosis- comorbid physical and psychiatric diagnosis [A], level of functioning, frailty, falls, forceful acts-abuse, forensic issues [F], collecting extra information pertaining to nutritional status, the environment in which the patient is living, constipation, urinary symptoms (incontinence/retention), and weight loss [E], understanding the ongoing stressors, suicidality, substance use disorder, sleep-related issues, sexual history, supervision of medication, safety issues, social support, spirituality and religiousness [S] and collecting the treatment history [T]. …”
Get full text

Is Exploration of Alternate Immune Pathways Needed in Hidradenitis Suppurativa? A Case of Atopic Dermatitis and Concurrent Hidradenitis Suppurativa Responding to Dupilumab by Sean McCormack, Noor Tazudeen, Benjamin C. Garden

“…We describe a patient with atopic dermatitis (AD) and comorbid HS, both of which improved several months into treatment with dupilumab. …”
Get full text

Extramedullary Solitary Plasmacytoma with Anaplastic Features of the Nasopharynx by Parikshit Padhi, Radwa El-Behery

“…He was treated with radiation alone given his comorbidities. Given there are no treatment guidelines, we would like to highlight this rare case and discuss different potential management options such as radiation, chemotherapy, surgery, or a combination of different modalities.…”
Get full text

Effectiveness of Cognitive Behavioral Therapy Techniques on Anxiety and Depression in Cancer Patients by Cem Soylu

“…Depression and anxiety are generally considered to be the most important psychopathological comorbidities of cancer patients and experienced by approximately one-third of cancer patients. …”
Get full text

Fungal Infections: Their Diagnosis and Treatment in Transplant Recipients by David H. Van Thiel, Magdalena George, Christopher M. Moore

“…The choice of a prophylactic agent should be based upon its ease of administration, lack of adverse effects, reduced likelihood of potential drug interactions, and its efficacy in patients with established risk factors and comorbid disease processes that include renal, hepatic, and chronic pulmonary disease. …”
Get full text

Rates of Tobacco Use Disorder, Pharmacologic Treatment, and Associated Mental Health Disorders in a Medicaid Claim Review Among Youth in Indiana, USA by Corey McBrayer DO, FAAP, Fangqian Ouyang MS, Zachary Adams PhD, Leslie Hulvershorn MD, Matthew C. Aalsma PhD

“…Mean age was 16.4 with 40% female. 1232 of the 6541 charts contained a TUD diagnosis equating to 1848 visits. A comorbid diagnosis of ADHD, cannabis use, and conduct disorder were more common in males (3.9% vs 1.3% in females; 3.4% vs .8%; and 2.8% vs .8%; P < .05). 808 scripts were provided to 152 of the 1232 youths, with 4.7% of those scripts a nicotine replacement product. …”
Get full text

Love Addiction - Current Diagnostic and Therapeutic Paradigms in Clinical Psychology. by Marilena Giovanna Maglia, Ines Lanzafame, Maria C Quattropani, Pasquale Caponnetto

“… # Methods From 30 November 2021 to July 2022 a review was conducted aimed at identifying the current diagnostic paradigms associated with this new behavioral dependence, investigating in depth what has not yet emerged, searching for strong and weak correlations with related theoretical constructs, comorbidities, investigate which evaluation scales are currently used and outline a guiding design that allows you to move between current scientific discoveries, searching for relevant studies in the databases PubMed, National Center for Biotechnology Information (NCBI), PsycINFO, MDPI, APA, ScienceDirect, and ReserchGate…”
Get full text

Clostridium subterminale Septicemia in a Patient with Metastatic Gastrointestinal Adenocarcinoma by Kevin M. Trapani, Leigh J. Boghossian, Elizabeth Caskey

“…Extensive GI and oncologic workup demonstrated multiple comorbidities and a primary GI cancer, which likely caused a breach in the GI mucosa and C. subterminale entrance into the bloodstream. …”
Get full text