Managing cardiovascular events, hyperglycemia, and obesity in type 2 diabetes through microRNA regulation linked to glucagon-like peptide-1 receptor agonists by Xiaolei Miao, Maryam Davoudi, Zahra Alitotonchi, Ensieh Sadat Ahmadi, Fatemeh Amraee, Ashraf Alemi, Reza Afrisham

“…Since recent evidence underlines the epigenetic role of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in the management of these comorbidities, this study compared the effects of these agents, namely liraglutide, semaglutide, dulaglutide, and exenatide, on miRNA regulation in the management of T2DM. …”
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Safety and effectiveness of different modes of labor induction among pregnant women delivering at referral hospitals in Dar es Salaam, Tanzania: a cohort study by Emmanuel Erasto, Martine A. Manguzu, Goodluck G. Nyondo, Manase Kilonzi, Alphonce Ignace Marealle, Ritah F. Mutagonda

“…Results Of the 322 women included, 198 (61.5%) were at term, and 210 (65.2%) had comorbidities. Overall, 80% of women achieved SVD following induction. …”
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Preventing epileptogenesis by interaction between inositol isomers and proteins by Lia Tsverava, Luka Kharkhelauri, Vincenzo Lagani, Giorgi Gamkrelidze, Veriko Bokuchava, Tamar Kiguradze, Merab Kokaia, Revaz Solomonia

“…All studied inositol isomers express long‐term beneficial effects on KA‐induced SRS and the associated comorbidities. Inositols can be successfully used in the future for translational research. …”
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Safety of vancomycin-loaded cement spacers for treating gram-positive periprosthetic joint infections in two-stage resection arthroplasty among patients with renal insufficiency by Yu-Chih Lin, Chih-Hsiang Chang, Chih-Chien Hu, Yung-Chieh Liang, Pang-Hsin Hsieh, Sheng-Hsun Lee, Sheng-Hsuan Lin

“…The study assessed comorbidities, renal function, specifics of the spacers, and vancomycin concentrations in joint fluid and blood. …”
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Anticancer Role of PPARγ Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes by P. J. Simpson-Haidaris, S. J. Pollock, S. Ramon, N. Guo, C. F. Woeller, S. E. Feldon, R. P. Phipps

“…However, longer survival is accompanied by increased incidence of comorbidities due, in part, to drug side effects and toxicities. …”
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Urinary Incontinence: Its Assessment and Relationship to Depression among Community-Dwelling Multiethnic Older Women by Luciana Laganà, David William Bloom, Andrew Ainsworth

“…Of the various mental health problems identified in the literature as being comorbid with UI, the most notable one continues to be depression. …”
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Alterations of amino acids in older adults with Alzheimer’s Disease and Vascular Dementia by Xin Ma, Xin-Meng Wang, Guo-Zhang Tang, Yi Wang, Xue‑Chun Liu, Shuai-Deng Wang, Peng Peng, Xiu-Hong Qi, Xin-Ya Qin, Yue‑Ju Wang, Chen-Wei Wang, Jiang-Ning Zhou

“…However, no significant distinction was found between healthy controls and VD patients. Considering comorbidities, cystine levels were higher in AD than in VD among non-diabetic patients, but not in those with diabetes. …”
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Internal Carotid Artery Aneurysm Mimicking Peritonsillar Abscess by Jacek Brzost, Anna M. Cyran, Martyna Waniewska, Miroslaw J. Szczepanski

“…The patient had a history of recent upper airway infection and cardiovascular comorbidities, including hypertension and ischaemic stroke complicated by extensive neurologic deficits. …”
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Sclerema Neonatorum in a Term Infant: A Case Report and Literature Review by Gloria Nakalema, Walufu Ivan Egesa, Patrick Kumbowi Kumbakulu, Martin Nduwimana, Amnia Diaz Anaya, Mirembe Stephen Kizito, Daniel Kavuma

“…This condition is peculiar to preterm neonates, especially those with comorbidities such as sepsis, congenital anomalies, congenital heart disease, and gastrointestinal and respiratory diseases. …”
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An Infected, Noncoronary, Bare Metal Stent Presenting as a Right Groin Abscess by Madiha Khan, Youssef Mourad, Alan Zeitlin, Martine Alice Louis, Syed Ali Rizvi, Kelly L. Cervellione

“…The patient was not an ideal candidate for explantation and bypass due to significant medical comorbidities and underwent local debridement and long-term antibiotic management instead. …”
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Candida associated infra-inguinal prosthetic vascular graft infection: A case report by Ahmet Deniz Kaya, Esma Nur Metin Kaya, Ihsan Alur

“…In the patients with comorbidities and who will undergo redo-surgery, excessive care should be given in terms of graft infections. …”
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Current Antibiotic Treatment and Outcome for Lower Respiratory Tract Infections by Alasdair P MacGowan, Tracey Halladay, Andrew M Lovering

“…Duration of hospital stay is a good marker of costs for hospital providers and may be affected by age. marital status and comorbidities. Antibiotic choice may have an impact on the duration of hospital stay by increasing side effects, predisposing patients to hospitalacquired infection or reduced clinical efficacy. …”
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Jacobsen syndrome associated with Shone’s complex: a case report by Andressa Brum, Larissa Valéria Laskoski, Fabiana Gonçalves de Oliveira Azevedo Matos, Luciana Paula Grégio d’Arce

“…Thus, the child is being monitored at a Craniofacial Anomalies Center with a multi-professional team in order to monitor her development and treat the associated comorbidities.…”
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An Unusual Cause of Acute Upper Gastrointestinal Bleeding: Acute Esophageal Necrosis by Nikhil R. Kalva, Madhusudhan R. Tokala, Sonu Dhillon, Watcoun-Nchinda Pisoh, Saqib Walayat, Vishwas Vanar, Srinivas R. Puli

“…The patients are usually older and are critically ill with shared comorbidities, which include atherosclerotic cardiovascular disease, diabetes mellitus, hypertension, chronic renal insufficiency, and malnutrition. …”
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Delayed bladder perforation due to screw loosening after pelvic ring injury surgery: a case report by Hyun-Chul Shon, Ho-Won Kang, Eic-Ju Lim, Jae-Young Yang

“…Genitourinary injuries are common comorbid injuries that have been reported to occur in 5% to 6% of all pelvic ring injuries. …”
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Pediatric Plastic Bronchitis: Case Report and Retrospective Comparative Analysis of Epidemiology and Pathology by Rebecca Kunder, Christian Kunder, Heather Y. Sun, Gerald Berry, Anna Messner, Jennifer Frankovich, Stephen Roth, John Mark

“…Further discussion is focused on the epidemiology of plastic bronchitis and a systematic approach to the histologic classification of casts. Comorbid conditions identified in this study included congenital heart disease (8), pneumonia (3), and asthma (2). …”
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An Uncommon Case of Plasma Cell Mucositis of the Tongue in a Young Man by Alessandro Antonelli, Fiorella Averta, Federica Diodati, Danila Muraca, Ylenia Brancaccio, Chiara Mignogna, Amerigo Giudice

“…This disease rarely manifests itself on the tongue, especially in young patients with no comorbidities. The management of PCM is mainly aimed at reducing the symptoms, and in our report, the treatment involved the use of systemic prednisone with an improvement of the quality of life. …”
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The Migraine-Ischemic Stroke Relation in Young Adults by Alessandro Pezzini, Elisabetta Del Zotto, Alessia Giossi, Irene Volonghi, Paolo Costa, Giorgio Dalla Volta, Alessandro Padovani

“…In the present paper, we will review epidemiological studies, discuss potential mechanisms of migraine-induced stroke and comorbid ischemic stroke, and pose new research questions.…”
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Nutrigenomic Functions of PPARs in Obesogenic Environments by Soonkyu Chung, Young Jun Kim, Soo Jin Yang, Yunkyoung Lee, Myoungsook Lee

“…Understanding the changes in obesogenic environments as a consequence of PPARs/nutrient interactions may help expand the field of individualized nutrition to prevent obesity and obesity-associated metabolic comorbidities.…”
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COVID-19 and Mucormycosis Coinfection: How Challenging It Is by Niranjan Nayak, Erum Khan, Debadatta Panigrahi

“…Diabetes mellitus though happens to be an independent risk factor both for severe COVID-19 and mucormycosis, administration of steroids is attributed as a precipitating factor for acquiring the comorbid condition. This opportunistic fungal infection is highly angioinvasive in nature because of which, clinical outcome of infection is invariably poor, especially with rhinocerebral or rhinoorbitocerebral variety of mucormycosis. …”
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