Fully-integrated medical home for people with severe and persistent mental illness: A description and outcome analysis of a Medicare Advantage Chronic Special Needs Program by Robert Myers

“…This population also has a high incident of chronic comorbid disorders that not only drives up healthcare costs but also significantly shortens longevity. …”
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Improving Prognosis Estimation in Patients with Heart Failure and the Cardiorenal Syndrome by Husam M. Abdel-Qadir, Shaan Chugh, Douglas S. Lee

“…Conventional assessments of left ventricular function, renal clearance, and functional status can be complemented with identification of coexistent comorbidities, medication needs, microalbuminuria, anemia, biomarker levels, and pulmonary pressures to derive additional prognostic data that can aid management and provide future research directions for this challenging patient group.…”
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Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress by Phillip W. Gold, Rodrigo Machado-Vieira, Maria G. Pavlatou

“…Major depressive disorder (MDD) is a chronic, recurrent, and severe psychiatric disorder with high mortality and medical comorbidities. Stress-related pathways have been directly involved in the pathophysiology and treatment of MDD. …”
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Cardiac Arrhythmia in a Patient with Sickle Cell Anemia and Falciparum Malaria Treated with Intravenous Artesunate by Abdulrahman Hummadi, Sultan Mubarki, Ayel yahay, Awad Mohammed Al-Qahtani

“…Treatment of severe malaria with artemisinin derivatives in patients with comorbid conditions such as sickle cell anemia must be considered with precaution. …”
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Prosthetic Aortic Valve Stenosis in End-Stage Renal Failure by Michael Mao, Mirelle El Ters, Sunil Mankad, Mira Keddis, Soon Park, Qi Qian

“…Although renal failure is one of the known comorbidities associated with rapid progression of aortic stenosis, it is unclear whether hemodialysis alters the progression of prosthetic aortic valve stenosis. …”
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Bilateral Reverse Total Shoulder Arthroplasty with Soft Tissue Release for Bilateral Posterior Fracture Dislocation after Status Epilepticus by George El Rassi, Nabil Dib, Joseph Maalouly, Rita Moukarzel, Dany Aouad

“…We conclude, after reviewing the literature, that there is no straightforward algorithm for treating such patients and that a clear classification should take into account both bone quality and patient comorbidities which has yet to be developed.…”
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A Review of Eating Disorders and Suicide Risk in Adolescence by Ida F. Dancyger, Victor M. Fornari

“…Epidemiological surveys are summarized, including suicide rates, parasuicidal behaviors, associated risk factors, and comorbid psychopathology. Critical implications for the comprehensive assessment and treatment planning, including safety considerations, are discussed. …”
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Neck of Femur Fracture in a Patient with a Chronic Osteomyelitis of the Ipsilateral Foot by Anne-Carolin Döring, Anne J. H. Vochteloo, Kees van Doorn, Rianne M. H. A. Huis in ’t Veld, Anil Peters

“…Treating patients with this type of comorbidities is challenging; therapeutic dilemmas can be major. …”
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An Unusual Occurrence of Hepatic Granulomas and Secondary Sitosterolemia in Turner Syndrome by JayaKrishna Chintanaboina, Pragnesh R. Shah, Thomas R. Riley

“…Of the three patients, first patient underwent liver transplantation; second patient remained stable on immunosuppressants; and third patient died from complications of decompensated liver cirrhosis as she declined liver transplantation due to multiple comorbidities. One patient had sitosterolemia, a rare inherited autosomal recessive disorder of cholesterol metabolism, after she ingested β-sitosterol supplement and had worsening liver function tests and lipid panel. …”
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Giant Adult Mesenteric Lipoma: A Rare Cause of Chronic Abdominal Distention and Discomfort by Houssam Khodor Abtar, Fahed Kheireddine Abdallah, Rayan Said Lakkis, Jad Jamal Terro, Nathalie Haidar Ismail, Mohammad Ahmad Al Raishouni, Houssein Haidar Ahmad, Kassem Mohammad Jammoul

“…Hereby, we present a case of a 54-year-old male patient with multiple comorbidities who was suffering from chronic abdominal discomfort and gradual increase of his abdominal distention over many years without seeking any medical attention. …”
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An Unusual Case of Stercoral Perforation in a Patient with 86 cm of Small Bowel by Alfin Okullo, Ghiyath Alsnih, Titus Kwok

“…In view of the patient’s advanced age, comorbidities, and the absence of intraperitoneal faecal contamination, manual disimpaction followed by wedge resection and primary closure of the perforation was done. …”
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Letter to the Editor of Journal of Otolaryngology regarding “Risk of diabetes in patients with sleep apnea: comparison of surgery versus CPAP in a long-term follow-up study” by Nguyen Truong, Bao Sciscent, F. Jeffrey Lorenz, David Goldrich, Neerav Goyal

“…Abstract Obstructive sleep apnea (OSA) is associated with multiple chronic comorbidities with treatments including continuous positive airway pressure (CPAP), upper airway surgery (UAS), and hypoglossal nerve stimulation (HNS). …”
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Bile acids and incretins as modulators of obesity-associated atherosclerosis by Andrijana Kirsch, Juergen Gindlhuber, Diana Zabini, Elena Osto, Elena Osto

“…Obesity is one of the major global health concerns of the 21st century, associated with many comorbidities such as type 2 diabetes mellitus (T2DM), metabolic dysfunction-associated steatotic liver disease, and early and aggressive atherosclerotic cardiovascular disease, which is the leading cause of death worldwide. …”
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Clinical and epidemiological characteristics and outcomes of patients affected by COVID-19 in the Intensive Care Unit by Priscila da Silva Timoteo, Kleyton Santos de Medeiros, Francis Solange Vieira Tourinho

“…Variables analyzed included age, gender, race, comorbidities, signs and symptoms, length of hospital stay, use of mechanical ventilation, medications, infections, monitoring, invasive devices, positioning, diet, comfort, and clinical outcomes. …”
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IgG4-Related Lymphadenopathy Mimicking Mediastinal Lymph Node Metastasis of Lung Cancer on ¹⁸F-FDG PET/CT by Ting-Chun Tseng, Hung-Pin Chan, Daniel Hueng-Yuan Shen, Chang-Chung Lin

“…This case underscores the need for considering differential diagnosis of PET-positive lymphadenopathy, especially in patients with comorbid conditions that mimic or coexist with malignancy.…”
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Heart Rate in Hypertension: Review and Expert Opinion by Jamshed Dalal, Arup Dasbiswas, Immaneni Sathyamurthy, Srinivasa Rao Maddury, Prafulla Kerkar, Sandeep Bansal, Joy Thomas, Sankar Chandra Mandal, Soura Mookerjee, Sivakadaksham Natarajan, Viveka Kumar, Nishith Chandra, Aziz Khan, R. Vijayakumar, J. P. S. Sawhney

“…(ix) It still remains unclear whether reducing HR in HTN without comorbidities alters the CV and mortality outcomes.…”
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Retrospective cross-sectional study on bronchiectasis in adult Aboriginal Australians: disease characteristics and comparison with ethnically diverse global bronchiectasis registry... by Timothy Howarth, Subash Heraganahally, Claire Gibbs, Lata Jayaram, Asanga Abeyaratne, Shiidheshwar J Ravichandran, Davaadorj Erdenebayar, Winnie Chen, Hubertus Jersmann

“…Smoking rates were higher at 85% compared with other registry cohorts (22–46%) as was the prevalence of comorbidities (97%): cardiovascular diseases (73%), diabetes mellitus (50%) and chronic obstructive pulmonary disease (83%) compared with other registry cohorts (4–32%; 6–14%; and 14–37%, respectively). …”
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Adaptive coping mechanisms use and associated factors among adult glaucoma patients attending the University of Gondar Comprehensive Specialized Hospital, Tertiary Eye Care and Tra... by Bisrat Misganaw Geremew, Biruk Fanta Alemayehu, Getenet Shumet Birhan, Biruk Lelisa Eticha, Mahtot Leykun Sisay, Woretaw Endalew Melese, Abebe Tilahun Mekonenne

“…Older age, urban residence, higher average family monthly income, moderate to severe visual impairment and the presence of ocular comorbidities were significantly associated with ACM. …”
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Differences in patients derived from otolaryngology and other specialties with sleep apnea by Constanza Salas, Jorge Dreyse, Andrea Contreras, Gonzalo Nazar, Constanza Astorquiza, Rodrigo Cabezon, Gonzalo Labarca, Jorge Jorquera

“…Abstract Background Snoring is a main concern in patients who consult an otolaryngologist (ENT physicians) and patients who have cardiovascular comorbidities or excessive daytime sleepiness who usually consult with other specialists. …”
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Prognostic signature of multimorbidity, geriatric syndromes and resources cluster in older in- and outpatients: a pooled secondary analysis with a 6-month follow-up by Thomas Benzing, Jill Stegemann, Anna Maria Affeldt, Luisa Mück, Anne Ferring, Laura Gerhards, Lena Pickert, Annika Bausch, Philipp Antczak, M Cristina Polidori

“…Based on a general linear model and a hierarchical clustering method, clusters of comorbidities, GS and GR were obtained.Results The study identified five clusters of GR-related GS, namely, psychosocial, iatrogenic, neurovegetative, sensorimotor and fluid dysbalance, along with two clusters related to GR, focusing on independence achievement and requirements- circumstances. …”
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