Anti-Inflammatory Nutrition as a Pharmacological Approach to Treat Obesity by Barry Sears, Camillo Ricordi

“…From knowledge of the impact of these dietary nutrients on these various molecular targets, it becomes possible to develop a general outline of an anti-inflammatory diet that can offer a unique synergism with more traditional pharmacological approaches in treating obesity and its associated comorbidities.…”
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Transcatheter Tricuspid Valve Replacement: Current Options and Future Perspectives by Guido Del Monaco, Gianluca Mincione, Alessandro Sticchi, Bernhard Reimers, Antonio Colombo, Antonio Mangieri

“…Traditionally managed medically and surgically, transcatheter therapies are now an emerging option, especially in patients with prohibitive surgical risk due to age or comorbidities. Transcatheter tricuspid valve replacement (TTVR) is emerging as a potential solution for patients suffering from TR with positive clinical data supporting its use in a wide range of anatomies and clinical settings. …”
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Robotically Assisted Single Anastomosis Duodenoileal Bypass after Previous Sleeve Gastrectomy Implementing High Valuable Technology for Complex Procedures by Ramon Vilallonga, José Manuel Fort, Enric Caubet, Oscar Gonzalez, José Maria Balibrea, Andrea Ciudin, Manel Armengol

“…After previous sleeve gastrectomy, surgical treatments in order to complete weight loss or comorbidities improvements or resolutions are possible. …”
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Sinusoidal Obstruction Syndrome (SOS) in Multiple Myeloma with Renal Failure by Urvi A. Shah, Sengottuvel Viswanathan, Beamon Agarwal, Aditi Shastri, Ioannis Mantzaris, Murali Janakiram, Noah Kornblum, Ira Braunschweig, Amit Verma, Yang Shi, John Reinus, Olga Derman

“…Although, melphalan and cyclophosphamide cause SOS less commonly than alkylating agents such as busulfan, physicians must use caution when administering these drugs to patients with underlying comorbidities such as renal failure that may increase the likelihood of development of SOS. …”
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Invasive Microascus trigonosporus Species Complex Pulmonary Infection in a Lung Transplant Recipient by Kelly E. Schoeppler, Martin R. Zamora, Noelle M. Northcutt, Gerard R. Barber, Gayle O’Malley-Schroeder, Dennis M. Lyu

“…Despite this apparent improvement, the patient’s pulmonary status progressively declined in the setting of multiple comorbidities, ultimately leading to respiratory failure and death.…”
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Development of a Multimodal Analgesia Protocol for Perioperative Acute Pain Management for Lower Limb Amputation by Roberta De Jong, Alexander J. Shysh

“…These pain mechanisms are explored and a proposed protocol for multimodal analgesia is outlined taking into account the common patient comorbidities found in this patient population.…”
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The Pathophysiology and Management of Coprophagia: A Report of Two Cases and Literature Review by Heela Azizi, Tasmia Khan, Cecilia Canale, Jisha Kallikkadan, Ivan Leung, Alexa Kahn, Dina Rimawi, Shantale Williams, Chidubem Matthew Obegolu, Sharon Paul, Shazia Chaudhry, Chiedozie Ojimba, Kodjovi Kodjo, Olaniyi Olayinka, Oluwole Jegede, Ayodeji Jolayemi

“…However, critical questions remain, related to characterizing effective management, features of associated comorbidities, time to recovery of symptoms, sustainability of recovery, and the determinants of outcomes. …”
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Remission of Cognitive Deficits in Parkinson’s Disease: Recovery from a Nonamnestic Mild Cognitive Impairment or Psychiatric Symptoms Remission? by Jonas Jardim de Paula, Marco Túlio Gualberto Cintra, Débora Marques Miranda, Maria Aparecida Camargos Bicalho, Edgar Nunes Moares, Leandro Fernandes Malloy-Diniz

“…The case report highlights the importance of controlling clinical comorbidities on the assessment and followup of mild cognitive impairment, especially on Parkinson’s disease.…”
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A Case of Emphysematous Osteomyelitis of the Midfoot: Imaging Findings and Review of the Literature by Marcela Mautone, Jessica Gray, Parm Naidoo

“…The organisms implicated in most cases of emphysematous osteomyelitis are anaerobes or members of the Enterobacteriaceae family. Significant comorbidities, such as malignancy and diabetes mellitus, frequently predispose to this condition, and high mortality rates have been reported. …”
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Frailty and the Risk of Polypharmacy in the Older Person: Enabling and Preventative Approaches by Martin C. Nwadiugwu

“…Frail older people have an inherent risk of polypharmacy due to the need to treat multiple comorbidities, thus leading to various negative effects on their health due to the adverse actions from the drugs. …”
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gas-forming pyomyositis in an immunocompetent patient: a case report and review by Jee Young Lee, Gyu Min Kong

“…We herein present the first documented case of Salmonella -induced gas-forming pyomyositis of the iliacus muscle in a healthy young man with no underlying diseases or comorbidities. Additionally, we reviewed cases of gas-forming pyomyositis in the literature and cases of pyomyositis caused by Gram-negative bacteria in immunocompetent patients.…”
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Symposium on Obesity and Asthma –November 2, 2006 by Louis-Philippe Boulet, Qutayba Hamid

“…It includes an overview of the various aspects of the relationships between asthma and obesity with regard to animal models; genetic, hormonal and physiological determinants; influence of comorbidities (eg, sleep apnea syndrome); epidemiology; clinical and psychological features; and management of asthma in the obese population.…”
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Varicella Zoster Reactivation Following mRNA Vaccination: Two Case Reports and a Review of Cutaneous Adverse Events of COVID-19 Vaccines by Milissa Makhlouf, Jennifer Akl, Alfred Ammoury

“…These two cases are of an 80-year-old female patient with multiple comorbidities and a previously healthy 57-year-old male patient who experienced varicella zoster reactivation post-COVID-19 mRNA vaccine (Pfizer, New York City, New York, USA) following the first and second dose…”
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Idiopathic Extensive Abdominal Aortic Thrombosis with Extension to the Celiac Trunk and Mesenteric Arteries in a Previously Healthy Female by Naima Mustafa Abdi, Mohamad Shieb, Masoud Shafiei

“…This mandates having individualized treatment for each patient depending on the presentation, age, etiology of the thrombosis, and patient’s comorbidities.…”
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Kidney Disease and Youth Onset Type 2 Diabetes: Considerations for the General Practitioner by Allison B. Dart, Elizabeth A. Sellers, Heather J. Dean

“…There is evidence to suggest that youth with T2DM are affected by the same comorbidities and complications as adults diagnosed with T2DM. …”
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Management of Hypertension and Diabetes in Obesity: Non-Pharmacological Measures by Joseph M. Pappachan, Elias C. Chacko, Ganesan Arunagirinathan, Rajagopalan Sriraman

“…Recently, bariatric surgery has emerged as an important and very effective treatment option for obese individuals especially in those with comorbidities like hypertension and diabetes. Though there are few effective drugs for the management of obesity, their efficacy is only modest, and they should always be combined with lifestyle interventions for optimal benefit. …”
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Opioid Dependent and Pregnant: What Are the Best Options for Mothers and Neonates? by Annemarie Unger, Verena Metz, Gabriele Fischer

“…Ideally, early and closely monitored treatment in an interdisciplinary team approach including social workers, nurses, psychologists, psychiatrists, gynecologists, anesthesiologists, and pediatricians should be provided. The treatment of comorbid psychiatric conditions, the resolution of financial, legal, and housing issues, and the psychosocial support provided have a significant effect on optimizing pregnancy outcomes. …”
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The Management of Infection and Colonization due to Methicillin-Resistant Staphylococcus aureus: A CIDS/CAMM Position Paper by Andrew E Simor, Mark Loeb, the CIDS/CAMM Guidelines Committee

“…Several studies have confirmed that MRSA infection is associated with increased morbidity and mortality compared with infections caused by susceptible strains, even when the presence of comorbidities is accounted for. Treatment of MRSA infection is complicated by the fact that these organisms are resistant to multiple antimicrobial agents, so treatment options are limited. …”
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Tricuspid Regurgitation in the Setting of Cardiac Implantable Electronic Devices by Omar M. Aldaas, MD, Gary Ma, MD, Quan Bui, MD, Ryan R. Reeves, MD, Ulrika Birgersdotter-Green, MD

“…Cardiac implantable electronic devices (CIEDs) have been increasingly used in the management of various rhythm disorders amidst an aging population with more prevalent cardiovascular comorbidities. Although generally well-tolerated and safe, implantation of CIEDs may result in or worsen tricuspid regurgitation (TR), which is associated with a higher risk of morbidity and mortality. …”
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Roles of the Chemokine System in Development of Obesity, Insulin Resistance, and Cardiovascular Disease by Longbiao Yao, Oana Herlea-Pana, Janet Heuser-Baker, Yitong Chen, Jana Barlic-Dicen

“…This low-grade chronic inflammation is thought to link obesity to insulin resistance and the associated comorbidities of metabolic syndrome such as dyslipidemia and hypertension, which increase risk of type 2 diabetes and cardiovascular disease. …”
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