Kidney disease among adults on tenofovir-based second-line antiretroviral therapy in Dar es Salaam, Tanzania by Sabina F. Mugusi, Grace A. Shayo, Philip G. Sasi, Lulu S. Fundikira, Eric A. Aris, Christopher R. Sudfeld, Ferdinand M. Mugusi

“…Background: Kidney disease is a growing non-AIDS-related comorbidity among people living with HIV (PLWH). Tenofovir disoproxil fumarate (TDF) can result in proximal tubulopathy and acute tubular injury, whereas atazanavir/ritonavir (ATV/r) can cause interstitial nephritis and renal stones, both of which can lead to chronic kidney disease. …”
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Atrial Arrhythmias in Patients with Severe COVID-19 by Kai-Yue Han, Qi Qiao, Ye-Qian Zhu, Xin-Guang Chen, Xing-Xing Kang, Gao-Feng Zhang, Xun-Chao Cai, Yong Du, Jing Jin, Ruo-Min Di, Chen-Xi Yang, Feng-Xiang Zhang, Ying-Jia Xu

“…This prospective study included patients with COVID-19 treated at the Leishenshan Temporary Hospital of Wuhan City, China, from February 24 to April 5, 2020. Demographic, comorbidity, and arrhythmias data were collected from patients with COVID-19 (n = 84) and compared with control data from patients with bacterial pneumonia (n = 84) infection. …”
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Simultaneous vs Staged Procedures for Bilateral Total Knee Arthroplasty: Reduced Infection, Cost, and Readmission Rates Associated With Simultaneous Procedures by Aaron Singh, BA, Travis M. Kotzur, BS, Kathleen Lundquist, MD, Blaire C. Peterson, BS, William H. Young, MD, Chance C. Moore, MD, Frank Buttacavoli, MD

“…Quasi-Poisson regression was performed to assess total charges. Demographics and comorbidities, measured via Elixhauser Comorbidity Index, were controlled for in our analysis. …”
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Risk factors for and incidence of osteoporosis in patients with breast cancer by gender : a nationwide cohort study by Jin Ah Lee, Hye Sun Lee, Soyoung Jeon, Dooreh Kim, YoungJoo Lee, SooYun Bae, Woo-Chan Park, Chang Ik Yoon

“…Matching was performed at a 1:5 ratio, based on age, treatment modalities and Charlson Comorbidity Index scores [CCI], resulting in 294 males and 1,470 females.Before and after matching, females consistently showed higher osteoporosis prevalence than males (16.7% vs. 5.0% before, 27.6% vs. 4.8% after, p < 0.001). …”
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Development and validation of a nomogram to predict survival in septic patients with heart failure in the intensive care unit by Tong Tong, Yikun Guo, Qingqing Wang, Xiaoning Sun, Ziyi Sun, Yuhan Yang, Xiaoxiao Zhang, Kuiwu Yao

“…A nomogram model was developed to predict short-term survival probabilities, using 13 variables: age, pneumonia, endotracheal intubation, mechanical ventilation, potassium (K), anion gap (AG), lactate (Lac), activated partial thromboplastin time (APTT), white blood cell count (WBC), red cell distribution width (RDW), hemoglobin-to-red cell distribution width ratio (HRR), Sequential Organ Failure Assessment (SOFA) score, and Charlson Comorbidity Index (CCI). The C-index was 0.730 (95% CI 0.719–0.742) for the training set and 0.761 (95% CI 0.745–0.776) for the test set, indicating strong model accuracy, indicating good model accuracy. …”
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Assessment of Technology Readiness in Norwegian Older Adults With Long-Term Health Conditions Receiving Home Care Services: Cross-Sectional Questionnaire Study by Sverre Bergh, Jūratė Šaltytė Benth, Lisbeth Dyrendal Høgset, Britt Rydjord, Lars Kayser

“…The participants completed the Readiness and Enablement Index for Health Technology (READHY) instrument, assessments of well-being (World Health Organization-Five Well-Being Index [WHO-5]), and assessments of demographic and clinical variables (sex, age, education, living situation, comorbidity, use of digital devices, and use of IT). …”
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History of coronary heart disease increased the mortality rate of patients with COVID-19: a nested case–control study by Yaping He, Lei Xu, Tian Gu, Qiao Chu, Zhangsheng Yu, Botao Fa, Anqi Li, Ruijun Wu

“…Objective Evaluate the risk of pre-existing comorbidities on COVID-19 mortality, and provide clinical suggestions accordingly.Setting A nested case–control design using confirmed case reports released from the news or the national/provincial/municipal health commissions of China between 18 December 2019 and 8 March 2020.Participants Patients with confirmed SARS-CoV-2 infection, excluding asymptomatic patients, in mainland China outside of Hubei Province.Outcome measures Patient demographics, survival time and status, and history of comorbidities.Method A total of 94 publicly reported deaths in locations outside of Hubei Province, mainland China, were included as cases. …”
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Adrenal hemorrhage in neonates: Incidence, perinatal characteristics and follow-up outcomes by Tek-Jū Tân, Yi-Li Hung, Chung-Min Shen, Wu-Shiun Hsieh

“…Neonatal jaundice was the major comorbidity. All infants had spontaneous resolution of AH before 7 months of age.…”
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A Clinical Monitoring Program of COVID-19 Outpatients: A Prospective Cohort Study by Hossein Kasiri, Cyrus Mahjub, Mohammadreza Mazaeri, Fahimeh Naderi-Behdani, Aliyeh Bazi, Monireh Ghazaeian, Sahar Fallah

“…This study was designed to investigate the demographics and clinical characteristics and comorbidity of nonhospitalized COVID-19 patients. Methods. …”
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Level of Satisfaction Among Patients Using Insulin Administered by Pen vs Vial/Syringe. An Observational Prospective Study by Valladales-Restrepo LF, Delgado-Araujo AC, Oyuela-Gutiérrez MC, Ospina-Arzuaga HD, Machado-Alba JE

“…., Calle 105 No. 14-140, Pereira, Risaralda, 660003, Colombia, Email machado@utp.edu.coPurpose: To determine the satisfaction of patients with diabetes mellitus who used subcutaneous insulin application devices in Colombia.Patients and Methods: An observational prospective study of patients with diabetes mellitus receiving insulin treatment in Colombia. Sociodemographic, comorbidity and pharmacological data were taken from a drug dispensing database. …”
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Machine learning model and nomogram to predict the risk of heart failure hospitalization in peritoneal dialysis patients by Liping Xu, Fang Cao, Lian Wang, Weihua Liu, Meizhu Gao, Li Zhang, Fuyuan Hong, Miao Lin

“…Baseline moderate or severe renal disease, systolic blood pressure (SBP), body mass index (BMI), age, Charlson Comorbidity Index (CCI) score were strongly associated with HF hospitalization, whereas age, CCI score, creatinine, age, high-density lipoprotein cholesterol (HDL-C), total cholesterol, baseline estimated glomerular filtration rate (eGFR) were the most significant predictors of mortality. …”
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Predictors of treatment outcome in higher levels of care among a large sample of adolescents with heterogeneous eating disorders by Erin E. Reilly, Sasha Gorrell, Alan Duffy, Dan V. Blalock, Philip Mehler, Harry Brandt, Susan McClanahan, Kianna Zucker, Naomi Lynch, Simar Singh, Catherine R. Drury, Daniel Le Grange, Renee D. Rienecke

“…Around 50% of the sample reported reliable decreases in eating disorder symptoms at stepdown and discharge, with 30% of the sample reporting reliable reductions in depression and anxiety. Psychiatric comorbidity, primary diagnosis, age, and eating disorder symptoms at admission consistently predicted treatment-related change, although patterns in findings varied across symptoms. …”
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Sociodemographic and lifestyle predictors of incident hospital admissions with multimorbidity in a general population, 1999–2019: the EPIC-Norfolk cohort by Kay-Tee Khaw, Robert Luben, Shabina Hayat, Nicholas Wareham, Paul P Pharoah

“…The associations between comorbid conditions and mortality risk are well established; however, few prospective community-based studies have reported on prior risk factors for incident hospital admissions with multimorbidity. …”
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The Clinical and Economic Impact of Employees Who Are Care Partners of Patients with Multiple Sclerosis by Disease Severity by Barry Hendin, Richard A. Brook, Ian A. Beren, Nathan Kleinman, Cindy Fink, Amy L. Phillips, Carroline Lobo

“…**Discussion:** Employee care partners of patients with moderate/severe vs mild MS had more comorbidities (ie, hypertension, gastrointestinal disease, depression, and anxiety) and higher pharmacy costs. …”
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Bariatric Surgery in Moderately Obese Patients: A Prospective Study by M. Cerci, M. I. Bellini, F. Russo, D. Benavoli, M. Capperucci, A. L. Gaspari, P. Gentileschi

“…The role of bariatric surgery in this context is currently debated, reserved for patients with comorbidity, as an alternative to conservative medical treatment. …”
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Determinants of Diabetic Nephropathy among Diabetic Patients in General Public Hospitals of Tigray, Ethiopia, 2018/19 by Teklewoini Mariye Zemicheal, Degena Bahrey Tadesse, Hagos Tasew Atalay, Girmay Teklay Weldesamuel, Gebrewahd Bezabh Gebremichael, Haben Nuguse Tesfay, Teklehaimanot Gereziher Haile

“…More attention has to be also given for old aged diabetic patients, long duration since diagnosis of diabetes mellitus, hypertension, and other comorbidities.…”
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Functional Dependency as a Marker for Positive SARC-F Screen among Older Persons at the Emergency Department by Edward Chong, Eileen Fabia Goh, Wee Shiong Lim

“…We compared the area under receiver operating characteristic curves (AUC) to detect SARC-F+ for MBI, IADL, frailty, age, cognition and comorbidity. Results SARC-F+ patients were older (86.4±7.6 years), predominantly female (71.5%) and frail (73.9%), more dependent on walking aids (77.2%), and had lower premorbid MBI (median 90.0 [interquartile range 71.0–98.0]) and IADL (4.0 [2.0–5.0]) (both p<0.001). …”
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Systemic therapy a risk factor for glaucoma development and progression by A.M. Getmanova, A.Yu. Brezhnev, A.V. Kuroyedov, V.I. Baranov, A.S. Dvornikov

“…Glaucoma treatment, in particular, in elderly patients, is often accompanied by systemic comorbidities and the intake of multiple systemic drugs. …”
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Long-term Patency and Complications of Endovascular and Surgical Revascularization for Takayasu Arteritis by Jiyoung Shin, Ara Cho, Ahram Han, Sanghyun Ahn, Sangil Min, Seung-Kee Min

“…The mean follow-up duration was 147.7±111.6 months. The most common comorbidity was hypertension (n=42, 75.0%), followed by heart failure (n=12, 21.4%). …”
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Concordance between the Different Cardiovascular Risk Scores in People with Rheumatoid Arthritis and Psoriasis Arthritis by Cristina Gonzalez-Martin, Silvia Grande Morais, Sonia Pertega-Diaz, Teresa Seoane-Pillado, Vanesa Balboa-Barreiro, Raquel Veiga-Seijo

“…Measurements: sociodemographic, anthropometric variables of the disease, comorbidity, cardiovascular risk, and therapeutic management. …”
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