Comparative Outcomes of Meropenem–Vaborbactam vs. Ceftazidime–Avibactam Among Adults Hospitalized with an Infectious Syndrome in the US, 2019–2021 by Marya D. Zilberberg, Brian H. Nathanson, Mark A. Redell, Kate Sulham, Andrew F. Shorr

“…Their mean [SD] Charlson comorbidity scores did not differ (3.6 [2.5] vs. 3.5 [2.5], <i>p</i> = 0.403). …”
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Incidence of chronic wounds in Singapore, a multiethnic Asian country, between 2000 and 2017: a retrospective cohort study using a nationwide claims database by Nicholas Graves, Kelvin Bryan Tan, Orlanda Q Goh, Ganga Ganesan, Yi Zhen Ng, Keith Harding

“…We aimed to estimate the incidence trend of a multiethnic Asian population.Design Retrospective cohort study.Setting Singapore’s nationwide claims database.Participants Singaporeans and permanent residents.Outcomes Patients were identified by International Classification of Disease, Ninth Revision, Australian Modification (ICD-9-AM) and ICD-10-AM codes from all admissions between 2000 and 2017, and categorised according to aetiology: venous, arterial, diabetic and pressure. Comorbidities were extracted from a national database of Charlson Comorbidity Index scores.Results Between 2000 and 2017, 124 023 wound-related claims among 86 631 patients were identified. …”
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Emotion dysregulation in adolescents is normalized by ADHD pharmacological treatment by Krisztina Kondi, Mária Takács, Evelyn Kovács-Posta, Claudia Szajli, Tünde Sebők-Welker, János M. Réthelyi, Nóra Bunford

“…Abstract Background Attention-deficit/hyperactivity disorder (ADHD) is associated with emotion dysregulation (ED) and in ADHD, beyond ADHD and comorbidity severity, ED confers increased risk for negative outcomes. …”
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Mortality Predictive Value of APACHE II and SOFA Scores in COVID-19 Patients in the Intensive Care Unit by Mohammad Taghi Beigmohammadi, Laya Amoozadeh, Forough Rezaei Motlagh, Mojgan Rahimi, Maziar Maghsoudloo, Behzad Jafarnejad, Babak Eslami, Mohammad Reza Salehi, Kazem Zendehdel

“…Among 204 severe COVID-19 patients, 114 patients (55.9%) expired and 169 patients (82.8%) had at least one comorbidity that 103 (60.9%) of them did not survive (P=0.002). …”
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Association of Albumin‐To‐Creatinine Ratio With Diabetic Retinopathy Among US Adults (NHANES 2009–2016) by Han Dai, Ling Liu, Weiwei Xu

“…Comprehensive evaluation of renal function and glycaemic control biomarkers, considering age‐ and comorbidity‐specific patterns, could improve DR risk prediction and management. …”
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Economic and Clinical Impact of Stroke and Warfarin Use for Patients with Non-valvular Atrial Fibrillation by Li Wang, Elyse Fritschel, Onur Baser

“…Despite the similarity in Charlson Comorbidity Index scores compared to non-stroke controls, stroke patients significantly higher clinical outcome rates during follow-up for acute coronary syndrome (ACS), ischemic attack, major and minor bleeding patients (p-values<0.0100), and the total cost incurred was nearly three times greater ($33,506 vs. $13,921, p-values<0.0001). …”
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Comparative effectiveness of laparoscopic versus open colectomy in colon cancer patients: a study protocol for emulating a target trial using cancer registry data by Semaw Ferede Abera, Gabriele Robers, Anika Kästner, Ulrike Stentzel, Kerstin Weitmann, Wolfgang Hoffmann

“…As the cancer registry data do not cover BMI, comorbidity, and previous abdominal surgery for non-malignant indications, the potential for residual confounding arising from these factors is a limitation of this study. …”
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Combination of age-adjusted d-dimer, platelet distribution width and other factors predict preoperative deep venous thrombosis in elderly patients with femoral neck fracture by Yunsong Li, Pengkai Cao, Tianyi Zhu, Yaqi Wang, Fengkai Wang, Liang Li, Xiangdong Liu, Yanrong Zhang

“…Demographic, injury, comorbidity, and laboratory variables were analyzed using univariate and multivariate approaches. …”
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Multi-disciplinary treatment of broncho-esophageal fistula in a high-risk single-lung patient by Rune Haaverstad, Kjell Ovrebo, Lorentz Sandvik, Håvard Seland, Gunnar Reksten Husebø, Vegard Skalstad Ellensen, Marit Farstad, Eivind Strandenes, Rajinder Sharma, Marianne Øksnes, Anders Kjellevold Storesund, Solveig Moss Kolseth

“…She had autoimmune comorbidity, a single lung, vocal cord paralysis and an extremely hostile thorax. …”
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Does it take the joints to stretch a mind? The ADHD and General Joint Hypermobility connection by Julia Kacperczyk, Witold Czyż, Michalina Wójcikiewicz, Filip Arczewski, Karol Dziedzic, Julia Kulbacka, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka

“…This paper investigates recently discovered links between ADHD and symptoms of joint hypermobility, and focuses on the prevalence of generalized joint hypermobility, as well as ADHD comorbidity in connective tissue-related conditions, such as Ehlers-Danlos syndrome and hypermobility spectrum disorder. …”
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Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (N = 19) by Carlijn de Roos, Julia Offermans, Samantha Bouwmeester, Ramón Lindauer, Frederike Scheper

“…There was no dropout (0%) and no adverse events were reported.Conclusions: The findings provide preliminary evidence of the safety, feasibility, and efficacy of six sessions of EMDR therapy for reducing paediatric PTSD and comorbidity in young children aged 1.5–8 years and, at the same time, decreasing parenting stress. …”
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Undernutrition risk and obesity increase the risk of osteosarcopenia in Mexican adults aged 50 and over: a prospective cohort study by Isabel Omaña-Guzmán, Ashuin Kammar-García, Luis Miguel Gutierrez-Robledo, Oscar Rosas-Carrasco

“…The final model was adjusted for sex, age, comorbidity, education, physical activity, and cognitive impairment.ResultsA total of 304 participants with two evaluations (baseline and follow-up) were included in the study. …”
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Median and Ulnar Neuropathy Assessment in Parkinson’s Disease regarding Symptom Severity and Asymmetry by Nilgul Yardimci, Ozlem Cemeroglu, Eda Ozturk, Gülsüm Gürlü, Esra Şahin, Saliha Bozkurt, Tugba Cengiz, Gulderen Karali, Hasim Cakirbay, Atilla İlhan

“…While increasing evidence suggests comorbidity of peripheral neuropathy (PNP) and Parkinson’s disease (PD), the pathogenesis of PNP in PD is still a debate. …”
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Statin prescriptions and progression of advanced fibrosis risk in primary care patients with MASLD by Andrew D Schreiner, William P Moran, Jingwen Zhang, Patrick D Mauldin, Justin Marsden, Mulugeta Gebregziabher, Chelsey A Petz, David G Koch, Chloe Bays

“…We developed Cox regression models for the time to a high-risk FIB-4 score with statin therapy as the primary covariate and adjusting for baseline fibrosis risk, demographic and comorbidity variables.Results The cohort of 1238 patients with MASLD was followed for a mean of 3.3 years, with 47% of patients receiving a prescription for a statin, and 18% of patients progressing to a high-risk FIB-4. …”
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Clinical Outcomes of COVID-19 and Impact on Disease Course in Patients with Inflammatory Bowel Disease by Panu Wetwittayakhlang, Farah Albader, Petra A Golovics, Gustavo Drügg Hahn, Talat Bessissow, Alain Bitton, Waqqas Afif, Gary Wild, Peter L Lakatos

“…Age ≥55 years (odds ratio (OR): 11.1, 95% CI: 1.8–68.0), systemic corticosteroid use (OR: 4.6, 95% CI: 0.7–30.1), active IBD (OR: 3.8, 95% CI: 0.7–20.8), and comorbidity (OR: 4.9, 95% CI: 0.8–28.6) were factors associated with severe COVID-19. …”
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Identifying Complex Scheduling Patterns Among Patients With Cancer With Transportation and Housing Needs: Feasibility Pilot Study by Allan Fong, Christian Boxley, Laura Schubel, Christopher Gallagher, Katarina AuBuchon, Hannah Arem

“…We apply the scheduling complexity algorithm to scheduling data from 38 patients with breast cancer enrolled in a 6-month comorbidity management intervention at an urban hospital in the Washington, DC area that serves low-income patients. …”
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Short-term outcome of endovascular stenting for symptomatic vertebrobasilar stenosis by Mohamed Abdel moneim Abdo Tolba, Mohammed Alaswad, Mohamed Mohamed Tawfik, Ahmed Zaki Akl, Mona Ali Eissa, Hala El-khawas, Hani Mahmoud Zaki Eldin, Mohamed Khaled Ahmed Elewa

“…The most prevalent comorbidity was a previous transient ischemic attack (TIA) in 15 patients (88.2%), followed by hypertension in 12 patients (70.6%), diabetes and hyperlipidemia in 10 patients each (58.8% for both). …”
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Quick sequential organ failure assessment score combined with other sepsis-related risk factors to predict in-hospital mortality: Post-hoc analysis of prospective multicenter study... by Ryo Ueno, Takateru Masubuchi, Atsushi Shiraishi, Satoshi Gando, Toshikazu Abe, Shigeki Kushimoto, Toshihiko Mayumi, Seitaro Fujishima, Akiyoshi Hagiwara, Toru Hifumi, Akira Endo, Takayuki Komatsu, Joji Kotani, Kohji Okamoto, Junichi Sasaki, Yasukazu Shiino, Yutaka Umemura

“…A logistic regression model was used to assess the predictive value of qSOFA for in-hospital mortality in models based on the following combination of predictors: 1) qSOFA-Only; 2) qSOFA+Age; 3) qSOFA+Clinical Frailty Scale (CFS); 4) qSOFA+Charlson Comorbidity Index (CCI); 5) qSOFA+lactate levels; 6) qSOFA+Age+CCI+CFS+lactate levels. …”
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Factors influencing therapeutic efficacy of denosumab against osteoporosis in systemic lupus erythematosus by Sung-Hwan Park, Seung-Ki Kwok, Wan-Uk Kim, Ji Hyeon Ju, Jiwon Yang, Youngjae Park, Jennifer Jooha Lee

“…Objective Osteoporosis is a common comorbidity in patients with SLE, and bone loss in patients with SLE has a multifactorial aetiology. …”
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Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial by Xue Gao, Lu Liu, Mei-Rong Pan, Hai-Mei Li, Yu-Feng Wang, Xue-Ying Liu, Zhong-Fang Fu, Qiujin Qian

“…Introduction Emotional disorders are highly prevalent among adolescents, with a high rate of comorbidity. Convenient and effective treatment options are needed to reduce costs and improve effectiveness. …”
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